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PubMed2002

The 50 million missing women.

The epidemic of gender selection is ravaging countries like India & China. Approximately fifty million women are "missing" in the Indian population. Generally three principle causes are given: female infanticide, better food and health care for boys and maternal death at childbirth. Prenatal sex determination and the abortion of female fetuses threatens to skew the sex ratio to new highs. Estimates of the number of female fetuses being destroyed every year in India vary from two million to five million. This review from India attempts to summarize all the currently available methods of sex selection and also highlights the current medical practice regards the subject in south-east Asia.

Female↗
PubMed1988

Different patterns of biting attack employed by lactating female mice (Mus domesticus) in encounters with male and female conspecific intruders.

Attacks by resident lactating female mice were examined in a variety of situations. Relatively few attack bites to vulnerable body regions were seen when pairs of unfamiliar lactating females fought, establishing social status prior to communal nesting. Sexually naive male and female intruders were equally prone to attack by lactating females, but patterns of bite attack generated by them were very different; males received the more damaging attacks. More signs of "fear" were seen in the lactating females' responses to male rather than female intruders. Varied motivations may underlie attacks by lactating females directed to conspecific intruders. Defensive patterns of biting by lactating females are more consistently directed towards males, intruders that are more likely to harm or destroy the litter. Although attacks by females rarely thwarted infanticide by male intruders, the behavior may acutely protect parental investment.

Aggression↗
PubMed1993

Communal reproductive success in rats (Rattus norvegicus): effects of group composition and prior social experience.

We compared the reproductive success and maternal behavior of sibling pairs of female Long-Evans rats (Rattus norvegicus) housed together from birth (familiar) to that of pairs of unrelated females housed apart during development (unfamiliar). Sires either remained in the colonies through weaning of their pups or were removed before parturition. Familiar animals reared more pups to weaning, were more likely to share in caring for their pups, and were less likely to exhibit infanticide than were unfamiliar ones. The presence of males in cages with pups had no direct effect on the reproductive success of females, but female pairs housed with males spent less time than female pairs housed alone caring for pups together in a combined nest. Conflicting evidence for communal rearing in populations of wild rats may reflect differences in the genetic relatedness or early social experience of female rats.

Animals↗
PubMed1979

Female transference and mate choice among Tana River red colobus.

Red colobus are one of a small number of primate species in which females have been reported to transfer between breeding groups more commonly than males. Several authors have hypothesised that in such species transference may serve to reduce the risk to females of producing offspring of lower fitness through inbreeding. The hypothesis offers no explanation of why females rather than males are responsible for outbreeding in these species, but remains plausible so long as male membership of breeding groups is relatively stable; for once members of one sex have evolved dispersal mechanisms reducing the risk of inbreeding, pressures on the other sex to do likewise will be lowered. Hence, if both sexes commonly migrate, the hypothesis is weakened. I describe here the membership dynamics of a group of Tana River red colobus, Colobus badius rufomitratus, which provide the first evidence of high rates of membership turnover by both sexes in primates, and speculate that the function of female transference in this case may be related to mate choice and the avoidance of infanticide.

Animals↗
PubMed1992

Communal nesting patterns in mice implicate MHC genes in kin recognition.

House mice (Mus musculus domesticus) form communal nests and appear to nurse each other's pups indiscriminately. Communal nesting probably functions to reduce infanticide, but it also makes females vulnerable to exploitation if nursing partners fail to provide their fair share of care. Kinship theory predicts that females will preferentially form communal nests with relatives to minimize exploitation and further increase inclusive fitness. Here we provide evidence from seminatural populations that females prefer communal nesting partners that share allelic forms of major histocompatibility complex genes. Such behaviour would lead to the selection of close relatives as communal nesting partners. Although criteria for the demonstration of kin recognition are currently embroiled in controversy, this is the first vertebrate study to meet Grafen's restrictive requirements: discrimination is based on genetic similarity at highly polymorphic loci, incidental correlations due to relatedness are experimentally controlled, and strong reasons exist for expecting the assayed behaviour to be kin-selected.

Animals↗
PubMed1998

Acts, omissions, intentions and motives: a philosophical examination of the moral distinction between killing and letting die.

Health care professionals frequently justify moral decisions by appealing to the acts and omissions distinction and the principle of double effect. These principles are often quoted and criticised in the nursing literature, particularly in relation to active and passive euthanasia. Authors are, however, inclined to acknowledge the fact that they are a philosophical minefield, but fall short of providing a substantial critical analysis. Those who uphold the acts and omissions distinction claim that we are morally less responsible for our omissions than for our acts. The principle of double effect suggests that there is a moral distinction between direct and indirect intention and that we are morally less responsible for that which we intend indirectly. This article offers an examination of these often quoted, but sometimes little understood, principles and it is hoped that it will serve as a basis for debate. Since the intention is to challenge assumptions which can lull us into believing that our moral decisions can be justified by appealing to principles such as these, it is necessary to examine them critically and to go beyond a superficial grasp of the implications of such distinctions. There is a tendency to appeal to the acts and omissions doctrine and the principle of double effect in life and death situations such as euthanasia, infanticide and abortion, but are they valuable tools which should be used in moral decision making, or are they so flawed that they can seriously mislead us when it comes to hard cases? The conclusion reached in this paper is that there is no significant moral difference between an act and an omission, particularly within the context of killing and letting die, and that the principle of double effect encourages hypocrisy rather than honesty.

Double Effect Principle↗
PubMedDate not supplied

["Where the doctors (...) handled the women beastly (...)". The Marburg lying in hospital from the view of the women].

In the statement she made in 1864, the housemaid, Elizabeth Gunkel, accused of infanticide, is reported to have said that she would have preferred to have drowned herself rather than look for a lying in hospital in which to give birth to her child. Even though they were feared by pregnant women due to the dubious--and often fatal--experiments performed there, lying in hospital continued to be the only places left for unmarried, abandoned or poverty-stricken women under financial or moral pressure to resort to. The lecture supplies a graphic illustration of the dynamics of interplay taking place in the process of medicalization within the system in which pregnant women became involved--state, legal system, church, science, traditional life-styles. As such is given a vivid picture of the daily life of women in the 19th century who became pregnant not by choice--their fears, hopes, despair and resistance to an environment in which they saw little real chance for themselves.

Female↗
PubMedDate not supplied

[Sudden death of twins: botulism because of contamination by pap vegetables].

Botulism is caused by the blockage of the neural transmission in the cholinergic synapses by botulinum neurotoxin (BoNT) which is produced by Clostridium botulinum or other Clostridia. The classic form of botulism occurs after the ingestion of food contaminated by BoNT. The course of the infection can be asymptomatic, mild with subtle paralysis ("failure to thrive") oder severe with generalized paralysis ("floppy infant"). Infected infants can also die sudden and unexpectedly. These deaths often are attributed to Sudden Infant Death Syndrome (SIDS), unless a thorough postmortem examination reveals Botulism. The rate of fatal Botulism falsely attributed to SIDS is not known, because it is difficult in most cases to show the causal relationship between contamination, disease and death. We report the sudden and unexpected simultaneous death of twins of 22 months which could be attributed to Botulism. Contamination of food, colonization of the gut by Clostridia and infection with specific pathomorphological changes could be proven. The initial suspicion of infanticide could be excluded. lt could be shown, that Botulism is a potential cause of simultaneous unexpected deaths in twins.

Botulinum Toxins↗
PubMed1983

[History of contraception and a look to the future].

The desire to limit procreation is as old as mankind. The means to reduce the number of children has been abortion and infanticide rather than contraception. But contraceptive methods have been used already in prehistoric times. They were partly logical, partly illogical and ineffective. Definite improvements were made in 19th century and a more scientific approach began in the 20th century. In order to master the problems of population explosion in developing countries intensive financial and organizational efforts have to be made.

Christianity↗
PubMed2003

Progesterone receptors mediate male aggression toward infants.

Neuroendocrine mechanisms that mediate male aggression toward infants are poorly understood. Although testosterone is known to enhance aggression in other social contexts, evidence that it modulates aggression toward infants is equivocal. We have found that male progesterone receptor knockout (PRKO) mice exhibit no infanticidal behavior and little aggression toward young. Male PRKO mice also display significantly enhanced parental behaviors. In wild-type mice, blockade of PR induces a behavioral phenotype similar to that of the PRKO males, whereas progesterone exacerbates aggressive tendencies toward infants. Aggressive behaviors directed toward adult males, by contrast, are unaffected by progesterone, PR antagonism, or PR gene deletion. Previously thought to be of diminished importance in male animals, PRs play a critical and specific role in modulating infant-directed behaviors in male mice.

Aggression↗
PubMed1994

Satanism, ritual abuse, and multiple personality disorder: a sociohistorical perspective.

During the past decade in North America, a growing number of mental health professionals have reported that between 25% and 50% of their patients in treatment for multiple personality disorder (MPD) have recovered early childhood traumatic memories of ritual torture, incestuous rape, sexual debauchery, sacrificial murder, infanticide, and cannibalism perpetrated by members of clandestine satanic cults. Although hundreds of local and federal police investigations have failed to corroborate patients' therapeutically constructed accounts, because the satanic etiology of MPD is logically coherent with the neodissociative, traumatic theory of psychopathology, conspiracy theory has emerged as the nucleus of a consistent pattern of contemporary clinical interpretation. Resolutely logical and thoroughly operational, ultrascientific psychodemonology remains paradoxically oblivious to its own irrational premises. When the hermetic logic of conspiracy theory is stripped away by historical and socio/psychological analysis, however, the hypothetical perpetrators of satanic ritual abuse simply disappear, leaving in their wake the very real human suffering of all those who have been caught up in the social delusion.

Animals↗
PubMed1997

Intra-alveolar pulmonary siderophages in sudden infant death: a marker for previous imposed suffocation.

Staining for iron showed previously overlooked intra-alveolar siderophages widely distributed in the lungs of two pairs of siblings, all of whom had hospital admissions for apparent life-threatening events (ALTEs) before dying suddenly at home. A mother and babysitter were convicted of their murder and manslaughter respectively. There were no siderophages in the lungs of a fifth infant whose death was included in the murder charge but who had no ALTEs. Bleeding from mouth or nose was observed during six of ten previous ALTEs suffered by these children and three unrelated infants in the same care. Such external hemorrhage is well described in imposed infant suffocation which may be one aspect of "Munchausen syndrome by proxy" child abuse. Our findings imply that there may also be intrapulmonary hemorrhage and that intra-alveolar siderophages can be a marker for previous abuse. Retrospectively we found diffusely distributed intra-alveolar siderophages in the lungs of seven of 158 infants with diagnoses of SIDS. Siderophages in such numbers demand an explanation and if this is not provided by clinical history or other necropsy findings should cause suspicion of previous imposed suffocation and infanticide and require further enquiry. The lungs should be stained for iron in all cases of sudden infant death.

Asphyxia↗
PubMed1995

Oral bis(tri-n-butyltin) oxide in pregnant mice. I. Potential influence of maternal behavior on postnatal mortality.

Pregnant Swiss mice were treated with 0, 5, 10, 20, and 30 mg/kg body weight of bis(tri-n-butyltin) oxide (TBTO) on d 6-15 of gestation. At birth litters were normalized to eight pups, and postnatal evaluation of pup growth rate and behavioral observations of dams were carried out. Litters were sacrificed on postnatal days (pnd) 7, 14, and 21, to perform hematological analysis, in connection with another study. Dam weight gain was impaired in all the treated groups (except at the lowest dose level) in the late phase of gestation. A high incidence of anticipated or delayed parturitions, without any correlation with fetal mass, was observed in the treated groups. All the treated dams showed a significant increase in resorptions, and a decrease in body weight gain between gestational day (gd) 6 and pnd 1. At birth, only the 20 and 30 mg/kg dose groups showed reduced litter size and reduced pup weight. Body weight gain reduction of pups persisted in wk 1 of life only in the 10 and 20 mg/kg dose groups. In addition, the maternal weight trend was affected during the lactation period in the higher dose groups. Postnatal death rate and growth rate of treated pups were affected by an altered maternal behavior; pups, apparently viable and with normal weight, were found often scattered throughout the cage with signs of wounds, and the percentage of dams that had not built a nest increased in the 10, 20, and 30 mg/kg dose groups. Total absence of parental care was noted in many litters, and many infanticidal events were reported. Our results seem to confirm low TBTO embryofetotoxicity, and strongly support the assumption that TBTO's toxicity to the mother is much stronger than its embryo-fetotoxic potential. Most of the reproductive parameters examined in this study were unaffected in the low-dose group, while some indices, such as gestation length and maternal weight gain between gd 6 and pnd 1, were markedly altered also at the 5 mg/kg dose level and appear to be sensitive parameters in assessing maternal toxicity.

Administration, Oral↗
PubMed2002

Sexual mimicry in hyenas.

Genital masculinization in female spotted hyenas has been widely explained as an incidental consequence of high androgen levels. High androgen levels, in turn, were supposed to be favored because they led to adaptive aggressive behavior. Incidental androgenization is no longer a tenable hypothesis, however, because genital masculinization has been shown to proceed in the absence of androgenic steroids. Thus, an alternative hypothesis is required. The genitals of spotted hyena females are not simply masculinized, but exhibit a detailed physical resemblance to the male genitalia. In the absence of satisfactory alternative explanations, we propose that selection may have favored sexual mimicry in females because they are more likely than males to be targets of aggression from other females. Male-like camouflage could theoretically be protective in three contexts: neonate sibling aggression, infanticide by conspecific females, and interclan territoriality. Current data suggest that if sexual mimicry is important, its effects are strongest among infants.

Aggression↗
PubMed2006

Female receptivity, embryonic diapause, and superfetation in the European badger (Meles meles): implications for the reproductive tactics of males and females.

The European badger Meles meles is thought to mate throughout the year with two mating peaks occurring in late winter/spring and summer/autumn. After mating, fertilized ova enter embryonic diapause (delayed implantation) at the blastocyst stage, which lasts up to eleven months. Even if mating is successful, however, the estrous cycle may continue during embryonic diapause, which suggests that female badgers are capable of superfetation (conception during pregnancy). This may increase female fitness by facilitating polyandry, and reduce the risk of infanticide by resident males through paternity confusion. Detailed understanding of female receptivity, specifically the association of superfetation with embryonic diapause, may explain field observations of seemingly inconsistent reproductive tactics of male badgers with regard to, for instance, whether or not they guard mates or defend territories. The combination of embryonic diapause and superfetation may occur in other mustelids; if so, the sociobiology of mustelids will need reevaluating, and the Mustelidae may prove to be a good model taxon for studies of sexual conflict in the reproduction of eutherian mammals.

Animals↗
PubMed1997

Postpartum mood disorders: clinical perspectives.

Mood disorders are common in women. A prepregnancy personal history of mood disorder (bipolar or major depression), premenstrual syndrome, or (possibly) postpartum blues places a woman at high risk for a postpartum exacerbation of symptoms. Untreated or unrecognized postpartum mood disorders can lead to serious psychologic and social consequences, in some cases even leading to suicide or infanticide. Women at risk for postpartum mood disorders need to be referred for psychiatric consultation before pregnancy and parturition. Informed, professional collaboration offers the best opportunities for prevention, as well as the earliest recognition and treatment of emergent symptoms.

Affective Disorders, Psychotic↗
PubMedDate not supplied

Gin Lane: did Hogarth know about fetal alcohol syndrome?

Medical historians have searched for evidence that the characteristics of fetal alcohol syndrome (FAS) were recognized long before its modern description in 1973. This search has often focused on the 'gin epidemic' in 18th century London, and especially William Hogarth's Gin Lane, which some authors allege reflects an awareness of the facial characteristics of the syndrome. While the 'gin epidemic' undoubtedly resulted in the increased birth of weak and sickly children, claims about Hogarth's awareness of the stigmata of the FAS are unfounded. The birth of weak and sickly children, and the high infant mortality rates associated with this period, long preceded the 'gin epidemic' and were primarily due to disease, starvation, exposure, and deliberate infanticide.

Alcohol Drinking↗
PubMed1995

Daily patterns of pituitary prolactin secretion and their role in regulating maternal serum progesterone concentrations across pregnancy in the Djungarian hamster (Phodopus campbelli).

Profiles of serum prolactin (PRL) and progesterone (P4) were determined in repeatedly (every 2 h) sampled female Djungarian hamsters (Phodopus campbelli) over a 24-h period on Days 3, 6, 9, 12, and 15 of the 18-day pregnancy. The first half of pregnancy was characterized by significant surges of PRL within a 2-h period around dawn (0500 h) and dusk (1900 h), with some females also showing a weak midday surge at 1300 h. By Day 9, dusk and midday surges were absent, but the dawn surge remained at its initial amplitude. On Day 12, no PRL surges were seen. Resumption of both the dusk and dawn PRL surges occurred on Day 15 of gestation. Considerable interindividual variability in the amplitude of PRL surges, the timing of PRL surges, and the number of surges per day was detected and would complicate any assessment of PRL levels based on single samples per female. Serum P4 concentrations were 8-10 ng.ml-1 before doubling on Day 15. A 3-day treatment of 50 and 300 micrograms bromocryptine (CB 154; on Days 13-15) effectively suppressed PRL during late pregnancy (Day 15) but did not alter serum P4 concentrations or interfere with parturition. Therefore, surges of PRL are not an essential luteotropic stimulus during late gestation. Compared to oil-injected controls, CB 154-treated females had a higher incidence of infanticide postpartum. Growth rates of the pups, mammary gland development, and successful delivery of milk to pups, however, did not differ between groups. Further studies will be required to determine the function of late-gestation PRL surges.

Animals↗