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[Difficulties in the diagnosis of secondary infectious endocarditis].

The paper is devoted to analysis of the case histories of 84 dead patients hospitalized to the Cardiosurgical Center for rheumatic heart disease in 1976-86. In 21 cases it was secondary infective endocarditis, unrecognized in 12 (57%) patients during life. Secondary infective endocarditis was shown to cause an increase in acute phase indices in 60% of the patients with acquired heart disease. Early diagnosis of disease made difficult the use of prednisolone in patients suffering from heart disease with a vague febrile state. Secondary infective endocarditis caused no specific changes of any of the studied indices. Its diagnosis should be based on a combined approach with account of rapid deterioration of a course of rheumatic heart disease and a therapeutic effect.

Adult↗

[Bacterial intracranial aneurysms associated with infectious endocarditis--report of 3 cases].

Three cases of bacterial intracranial aneurysms associated with infective endocarditis are reported. All of the patients were successfully treated by various combinations of cardiac surgery, neurosurgery and chemotherapy with antibiotics. Case 1: A 39-year-old female was admitted with the complaint of sudden onset of severe headache following persistent fever of several month's duration. CT scan revealed a left frontal old hematoma and angiography detected an aneurysm located in the frontal ascending branch of the left middle cerebral artery. After 2 weeks' antibiotic therapy, the second angiography showed the aneurysm to be decreased in size. The third angiography, performed 2 weeks after cardiac valve replacement for infective endocarditis, demonstrated complete resolution of the aneurysm. Case 2: A 19-year-old male entered hospital with high fever and chills. In addition to infective endocarditis, CT scan and angiography revealed an aneurysm arising from the distal portion of the left posterior cerebral artery. The patient was treated with high dose antibiotics and then his general condition improved. However, angiography examined 4 weeks after the initial study demonstrated the aneurysm to be apparently enlarged. Therefore, the aneurysm was excised before cardiac surgery. Repeated angiography after valve replacement showed no further aneurysm. Case 3: A 30-year-old female was admitted on the diagnosis of infective endocarditis and meningitis. CT scan showed abnormal density areas in the right frontal lobe and the left temporal lobe.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[Mycotic aneurysm of the pulmonary artery complicating infectious endocarditis].

The authors report the case of a 7 year-old boy, in whom a mycotic aneurysm of the lobar inferior left pulmonary artery had been found in the course of a staphylococcal endocarditis of the tricuspid valve. Surgical removal of the aneurysm was followed by a thrombosis of this artery. This is a rare complication after infective endocarditis. Analysis of literature data shows that the rupture of these aneurysms frequently occurs; therefore, systematic surgical treatment is recommended whenever the anatomic conditions make it possible.

Aneurysm, Infected↗