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[Contact sensitization to pharmaceutic aids in dermatologic cosmetic and external use preparations].

From April 2001 to December 2002, a group of 514 patients (178 men, 336 women, average age 42.8 years) suffering from chronic eczema were tested by means of epicutaneous tests for contact hypersensitivity to selected auxiliary substances of dermatological external and cosmetic preparations. In 194 patients, the principal diagnosis was atopic eczema. Of the preservatives, the most frequently sensitizing agents were Thiomersal in 13.6%, phenylmercuric acetate in 7.8%, formaldehyde in 5.6%, Bronopol in 5.1%, chlorohexidine in 3.3%, dibromodicyanobutane/phenoxyethanol in 2.9%, chloroacetamide in 2.1%, Kathon CG and parabenes in 1.9%, imidazolidinyl urea and diazolidinyl urea in 1.4%, glutaraldehyde in 1.2%, DMDM-hydantoin in 1.0%, dichlorophen in 0.8%, sorbic acid, phenoxyethanol and triclosan in 0.6%, benzalkonium chloride, Quaternium-15 and chlorocresol in 0.4% and chloroquinaldol in 0.2% of the group of patients. Of antioxidizing agents, it was dodecyl gallate in 2.3%, butylhydroxyanisol in 1.2%, propyl gallate in 0.6%, butylhydroxytoluen in 0.4% of the group o patients and of emulsifiers, alcohols lanae in 5.1%, triethanolamine in 1.6% and propylene glycol in 0.4% of the group of patients. A complete list of contained substances in drug information sheets of both pharmaceutical and cosmetic preparations seems necessary particularly for patients suffering from eczema. The results of the test can serve as feed-back information for the manufacturers of both pharmaceutical and cosmetic preparations.

Adolescent↗

Do underarm cosmetics cause breast cancer?

Although animal and laboratory studies suggest a possible link between certain chemicals used in underarm cosmetics and breast cancer development, there is no reliable evidence that underarm cosmetics use increases breast cancer risk in humans. This article reviews the evidence for and against the possible link between breast cancer and underarm cosmetics and highlights the need for further research to clarify this issue.

Aluminum Hydroxide↗

[Endoscope-assisted thyroidectomy by chest approach with good cosmetic results].

OBJECTIVE: To explore the feasibility, safety, and cosmetic efficacy of endoscope-assisted thyroidectomy (EAT) by chest approach. METHODS: Fifty-one patients with single benign thyroid nodule < or = 4.0 cm in diameter, and without history of neck surgery or irradiation, 8 males and 43 females, aged 33.9 (18-64), underwent endoscope-assisted thyroidectomy by chest approach: a skin incision with the length of 4 cm was made in the chest, an endoscope was inserted, and subtotal or total thyroidectomy with the technique similar to that in conventional surgery was performed with naked eyes. RESULTS: Subtotal thyroidectomy was performed in 49 patients, and total excision of unilateral thyroid lobe plus isthmus lobectomy and contralateral partial lobectomy was performed on the other 2 patients. No patient was transferred to traditional surgery. Only one case showed palsy of recurrent nerve. Most patients expressed with the cosmetic results. CONCLUSION: EAT is a feasible and safe procedure with rather good cosmetic

Adolescent↗

[Dental ethics, esthetics and cosmetics].

By means of adhesive dentistry sound teeth can be made more beautiful without damaging tooth structure. This is called cosmetic dentistry. Within the dental profession there is a discussion about the following questions: is cosmetic dentistry real dentistry? Is it ethical to render cosmetic services to patients? In this article arguments are displayed to answer this question in a positive manner.

Adult↗

Laser abrasion for cosmetic and medical treatment of facial actinic damage.

Previous studies have shown the carbon dioxide (CO2) laser to be effective in the treatment of actinic cheilitis. After CO2 laser abrasion, normal skin and marked cosmetic improvement of the lip were noted. In our study, twenty-three patients were treated with CO2 laser abrasions for cosmetic improvement of facial lines and actinic changes. Pre- and postoperative histopathologic examinations were made on two patients. Preoperative examination of specimens from actinically damaged skin showed atypical keratinocytes in the basal layer of the epidermis, with overlying dense compact orthokeratosis and parakeratosis. Abundant solar elastosis was seen in the papillary dermis. Postoperative histologic specimens showed a normal-appearing epidermis with fibrosis in the papillary dermis and minimal solar elastosis (about four weeks after laser treatment). At present, various modalities are available for the regeneration of the aged skin, including chemical peels and dermabrasion. Significantly fewer complications were noted with CO2 laser abrasion than with these methods. Thus, CO2 laser abrasion can be useful in the cosmetic and medical treatment of the aged skin. Marked clinical and histologic improvement has been demonstrated.

Adult↗

Patients' perceptions of their cosmetic appearance more than ten years after radiotherapy for basal cell carcinoma.

Of 47 elderly patients treated by simple radiotherapeutic techniques for basal cell carcinomas, 12 are alive and free of disease more than 10 years after treatment. They were asked to rate their perception of the current cosmetic appearance of their lesions on a scale consisting of: excellent, very good, good, mediocre, and poor. Six of the 12 rated their cosmetic appearance as excellent, three considered it very good, and three called it good. Despite undeniable objective deterioration of the cosmetic appearance of irradiated basal cell carcinomas, patients appear to be pleased with the results.

Aged↗

Cosmetic contact lenses in the care of the child.

As their name implies, cosmetic contact lenses are used to hide or cover blemishes or disfigurements of the iris, cornea, or sclera. A wide variety of options are available to the optometrist in attempting to aid a child with an ocular disfigurement. The customized artist-painted scleral shell is ideal in many cases, but a surprising number of defects can be adequately camouflaged with corneal lenses presently available from laboratories. The future use of cosmetic soft lenses is promising, and since many conditions involving the need for optical correction are capable of provoking future visual disorders, infants today can look forward to better vision when a cosmetic contact lens is fitted early in life.

Child↗

[Cosmetic and functional diagnosis in vertical dysmorphisms of the face].

If it is accepted that 68 p. 100 of patients consulting for maxillofacial malformations do so for cosmetic reasons then the facial deformity must be taken into account in a similar manner to the maxillodental dysmorphism. A morphological cosmetic diagnosis must therefore be combined with a skeletal functional diagnosis. Just as teleradiographic techniques (Tweed-Sassouni-Delaire) contribute to the differention of the various types of vertical dysmorphism, photographic analysis procedures (Fomon-Broadbent and Mathews-Baud) are necessary for the study of anterior vertical abnormalities. A global diagnosis (functional and cosmetic) requires evaluation of results of these different examination techniques evaluation of establish the choice of operation responding to the wishes of the patient while respecting the occlusal criteria ensuring durability of results.

Adolescent↗

A cosmetically acceptable incision for the median sternotomy.

The median sternotomy incision has become the routine approach for most cardiac surgical procedures. This generally gives a poor cosmetic result. In certain patients, particularly those who are asymptomatic and undergoing short, low-risk procedures, cosmetic considerations are of relatively greater importance. We describe a transverse skin incision which gives adequate exposure for the median sternotomy. It has been used successfully in 40 female patients. This technique provides a cosmetically acceptable incision for the median sternotomy approach.

Adult↗

Marketing strategies for the cosmetic practice.

Appropriate marketing business systems need to be in place to attract and sustain a cosmetic dentistry patient base. Marketing for this sector is most effective when consistently patterned after businesses with high-end consumer services and products. Motivating patients of record and potential new patients to choose cosmetic dental services involves implementing both basic marketing and a series of cosmetic-specific marketing strategies. Consultants are valuable for the process of developing a strategic plan and making recommendations for developing new marketing business systems.

Advertising↗

Cosmetic result of lower midline laparotomy wounds: polybutester and nylon skin suture in a randomized clinical trial.

OBJECTIVE: To compare the cosmetic outcome of lower midline laparotomy scars using either nylon or polybutester suture for skin closure. METHODS: A randomized clinical trial compared polybutester skin suture with nylon for lower midline laparotomy wounds in 50 women undergoing gynecologic surgery. Scar hypertrophy, scar width, scar color, the presence of cross-hatching marks, and a total score were assessed in all patients at 18 months following surgery and compared by nonparametric statistical tests. RESULTS: The wounds closed with polybutester suture were significantly less hypertrophic than those closed with nylon. Regardless of the suture material used, the lower part of the laparotomy scar showed an inferior cosmetic result compared with the upper part underneath the umbilicus for scar hypertrophy, scar width, and the total scar score. CONCLUSIONS: Polybutester skin suture diminishes the risk of hypertrophic scarring because of its special properties allowing it to adapt to changing tensions in the wound. Increased closure tension of the skin in the midline region above the pubic bone may be caused by a relative immobility of the skin. Scar cosmetics in this area may be improved by extra subcuticular suture support.

Cicatrix↗

Considerations for cosmetic surgery in the black population.

The availability of cosmetic surgical procedures to the general public, especially blacks, has become increasingly widespread. Aesthetic surgeons should not be deterred from performing these procedures in blacks. The myth that all black patients develop keloids or dyspigmentation after surgery should be dispelled; however, in those patients with a history of keloid formation or hypertrophic scarring, elective cosmetic procedures should be either withheld or performed with extreme caution. In general, the cosmetic surgeon can proceed with surgery in blacks and attain good aesthetic results if the procedures are slightly modified when indicated to minimize pigmentary changes and scarring and to maintain ethnic congruency.

Black People↗

Comparison of cosmetic and physicochemical properties of six topical corticosteroid creams.

The cosmetic and physicochemical properties of six topical corticosteroid creams were evaluated and compared. The following creams were provided in blinded tubes: Elocon, Westcort, Lidex, Kenalog, Valisone, and Cutivate. The following properties were evaluated in vitro: stiffness (hardness), grittiness, color, odor, homogeneity (phase separation), pH, weight loss, and tackiness (stickiness). Samples of the creams were evaluated by light microscopy and scanning electron microscopy to identify particle and droplet distribution, particulate contamination, and microscopic homogeneity of the products. Cutivate ranked number 1 in each category and received the best overall score for each of the cosmetic and physicochemical properties evaluated. The cosmetic and physicochemical properties of Elocon, Westcort, Lidex, and Kenalog were found to be similar to one another with regard to overall score but inferior to Cutivate. Valisone was also good with regard to overall score but was ranked less acceptable due to a strong odor.

Administration, Topical↗

Comparison of automated and traditional minimum inhibitory concentration procedures for microbiological cosmetic preservatives.

Minimum inhibitory concentration (MIC) is used to test resistance of microorganisms against antibiotics and to test cosmetic preservatives. This research expanded traditional MIC with automation and application of colorimetric endpoint MIC. All experiments included common cosmetic preservatives and microorganisms used in testing preservative efficacy. An autodilutor using three 96-well microtiter plates processed 6 preservatives against 1 microorganism in 15 min. The unique tip design made it possible to accurately deliver viscous test materials that cannot be dispensed accurately with vacuum or fluid-filled systems. Tetrazolium violet, a redox indicator, provided a visual color change from clear to purple at the MIC. Optimum concentration of tetrazolium violet was 0.01% with addition of 0.2% glucose to Mueller-Hinton broth for both gram-positive and gram-negative bacteria. The colorimetric endpoint was evident after 24 h from previously cryogenically stored organisms that were thawed before use and after 4 h for 18-24 h broth cultures subcultured from agar plates. The autodilutor accurately pipetted viscous cosmetic products such as hand lotion and shampoo, which cannot be pipetted with a traditional micropipetter.

Azoles↗

The ageing face. Stemming the tide with cosmetic surgery.

Over the past decade there has been growing media focus on cosmetic surgery, with greatly increased public acceptance which has spread through all ethnic groups in our society, especially in second and third generation Australians. The acceptance and desire for male cosmetic surgery is also increasing but not at the level of their female counterparts. Increased requests for cosmetic surgery now cover all socioeconomic groups.

Aged↗

Creating facial harmony with cosmetic dentistry.

With the increased awareness that optimal cosmetic dentistry can have on self-image, self-esteem, and self-confidence, patients are no longer just wanting to close gaps or whiten their smiles. Patients are becoming very conscious of the size, proportion, and position of their teeth as related to their smile and face. By incorporating the art and science of cosmetic dentistry into our enhancement therapy, we are able to create excellent results on a consistent basis. This review explores the impact that cosmetic dentistry can have on creating facial harmony. The discussion demonstrates the importance of a proper esthetic diagnosis as well as a thorough bioesthetic evaluation of each patient. This review also stresses the importance of an objective and subjective assessment and how a detailed evaluation of each patient can help create harmonious and natural smiles.

Beauty↗

Ocular effects of cosmetic products and procedures.

Cosmetic products and procedures can produce adverse effects on the ocular surface, ranging from mild discomfort to vision-threatening conditions. Complications of skin and eye products can be related to allergy or toxicity, often attributable to perfumes. Complications of blepharoplasty may be associated with overcorrection, scarring, or uneven contour of the lid margins, conditions that can cause significant ocular surface disease until they are corrected. Ocular surface effects of botulinum toxin injection include dry eye syndromes and also epiphora. More serious complications occur (rarely) and are dose- and location-related. Adverse effects of micropigmentation procedures involve pathological processes or, simply, poor cosmetic results. In certain youth cultures, special-effect contact lenses and even decorative conjunctival implants have gained popularity, presenting a wide variety of dangers, often attributable to poor education about care and hygiene.

Cosmetic Techniques↗

The contributions of the European cosmetics industry to the development of alternatives to animal testing: dialogue with ECVAM and future challenges.

COLIPA (the European Federation of the Cosmetics Industry) represents 24 international companies and 2000 small and medium-sized enterprises. Together with ECVAM, COLIPA has been involved in the development and validation of alternative methods since the beginning of the validation efforts. The work of the Steering Committee on Alternatives to Animal Testing (SCAAT) is based on collaboration between companies, but also with academia, trade associations, the Scientific Committee on Cosmetics and Non-Food Products (SCCNFP), European Commission Directorates General, and ECVAM. Some success has been achieved, but some validation efforts have failed. One lesson is that the search for alternatives requires a lot of humility.

Animal Testing Alternatives↗