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At least 487 records · Page 27Linked to original sources
PubMed1979

Computerized gas-liquid chromatographic method for content uniformity analysis of dicyclomine hydrochloride capsules and tablets.

An automated, computerized method is presented for the content uniformity determination of dicyclomine hydrochloride capsules and tablets, using up to 4 automatic sampler-equipped gas chromatographs interfaced with a minicomputer. A 3% OV-17 column is used with anthracene as an internal standard. Five sample injections are bracketed by standard mixtures containing about 90 and 110% of the labeled dicyclomine hydrochloride. Data are taken on-line simultaneously from each gas chromatograph and a computer-generated report is produced. Calculations use a BASIC program with linear fit of the 90 and 110% standard mixture. Individual tablet or capsule results are printed in milligrams and per cent declared, including summary calculations of average, high, low, standard deviation, and coefficient of variation. The GLC results are comparable (within 1%) to those obtained using the USP procedure.

Autoanalysis↗
PubMed1980

[Number of retinal ganglion cells and visual discriminative performance in split-chiasma rats].

The relationship between post-operative retention, learning and transfer of visual discriminative tasks and number of retinal ganglion cells undegenerated after chiasma section was analyzed with a multiple linear regression program, stepwise procedure. Post-op retention of an intensity discrimination task significantly depends on the number of retinal ganglion cells in the most spared eye. Post-op learning and transfer of an orientation discrimination task significantly depends on 1) the total number of undegenerated ganglion cells and 2) their uniform distribution in both eyes.

Animals↗
PubMed1995

Determining the optimal mix of exercise activities using mathematical programming.

Several mathematical programming models designed to develop optimal exercise programs are described. The models can be adapted to various individuals so that unique objectives and constraints can be met. The models can be used to design individualized exercise programs for a wide variety of people. Models can meet the needs of those who exercise for recreational purposes, athletic achievements and/or rehabilitative purposes. As the objectives of an exercise program and the constraints on it change over time, individuals must occasionally review the relevancy of the objective function and constraints. The model must then be updated so that the updated optimal exercise program can be designed. An illustrative example that deals with the development of an overall fitness program for individuals exercising for recreational reasons is described.

Exercise↗
PubMed1993

A national study of the efficiency of hospitals in urban markets.

Using a sample of 3,000 urban hospitals, this article examines the contributions of selected hospital characteristics to variations in hospital technical efficiencies, while it accounts for multiple products and inputs, and controls for local environmental variations. Four hospital characteristics are examined: hospital size, membership in a multihospital system, ownership, and payer mix (managed care contracts, percent Medicare, and percent Medicaid). Ownership and percent Medicare are consistently found to be related significantly to hospital efficiency. Within the ownership variable, government hospitals tend to be more efficient and for-profit hospitals less efficient than other hospitals. Higher percentages of Medicare payment are negatively related to efficiency. While not consistently significant across all five of the MSA size categories in which the analyses are conducted, possession of managed care contracts, membership in a multihospital system, and size all are consistently related positively to hospital technical efficiency. These variables are also all significant when the hospitals are examined in a combined analysis. Percent Medicaid was not significant in any of the analyses. Implications for policy and the need for methodological work are discussed.

Analysis of Variance↗