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PubMed1988

Voluntary health agencies as target populations for epidemiologic research.

The ability of two voluntary health agencies to provide suitable target populations for epidemiologic research was explored in a pilot study of epilepsy. The results suggest that, properly approached, voluntary agencies offer advantage for this purpose. In the first agency (Group A), subjects were recruited by mail, producing a response rate of 15%. In the second agency (Group B), subjects were recruited by telephone, producing a response rate of 87%. A structured, precoded telephone interview about personal and family history of seizure disorders was administered to both groups of subjects. Subjects in Group A gave permission to contact a higher proportion of their eligible relatives than did those in Group B (73 vs 57%). Permission was obtained more often for relatives reported to have had seizures (Group A 86%, Group B 78%) than for other relatives. 89% of relatives contacted directly agreed to be interviewed. Consent forms for medical record review were signed and returned by 95% of Group A and 77% of Group B subjects. Diagnoses of etiology and seizure type of epilepsy based on the interview data agreed with diagnosis based on the medical records in most cases. In first-degree relatives of subjects with epilepsy, reported rates of epilepsy did not appear to be seriously biased.

Adult↗
PubMed1993

Effects on response rates and costs of stamps vs business reply in a mail survey of physicians.

In the general population, the use of stamps rather than business reply postage significantly improves response rates in mail surveys. Among physicians, however, a smaller effect might be anticipated due to their greater sophistication. An experiment was conducted to test the hypothesis that stamps would improve response rates and lower costs in a physician survey that included intensive follow up. In 1989, 380 physicians who reported providing primary care were surveyed. The protocol included two mailings, a postcard reminder, and two telephone reminders. Physicians were randomly assigned to receive a return envelope with a first-class stamp or an envelope that had been preprinted "business reply mail" in the first and second mailings. Response rates, calculated as completed surveys divided by eligible physicians, were 83.8 and 72.1% for stamps and business reply respectively, a difference of 11.7 percentage points (p < 0.01). Moreover, the total cost per completed survey was $11.18 for the physicians receiving stamps and $14.25 for the physicians receiving business reply. As in mail surveys of the general public, the use of first-class stamps on return envelopes both improves response rates and reduces cost in surveys of physicians.

Data Collection↗
PubMed1995

Timing payments to subjects of mail surveys: cost-effectiveness and bias.

Although mailed surveys are an important component of epidemiological research, results from mailed surveys are often suspect because of poor response rates and the potential for nonresponse bias. Previous work has demonstrated that paying subjects to complete questionnaires increases response rates, but this work has not well addressed the impact of the timing of incentives on total cost, cost effectiveness, and response bias. We surveyed 400 university employees about health benefits. By random allocation, half received a check for $5 along with the mailed survey, and the other half received the promise of $5 on return of a completed survey. The response rates for both groups were about the same (64 and 59%, respectively), but prepayment was less expensive in aggregate and less expensive per response. In addition, we found that subjects with lower salaries were more likely to respond when paid in advance. We conclude that prepayment may actually be less expensive and more cost effective than payment on completion, but that the timing of payment may influence the profile of respondents.

Adult↗
PubMed2006

Comparison of Web and mail surveys for studying secondary consequences associated with substance use: evidence for minimal mode effects.

OBJECTIVES: The present study examined the impact of using a Web survey vs. a more traditional mail survey on the reporting of secondary consequences associated with substance use by undergraduate students. METHODS: During the spring of 2001, a survey questionnaire was administered to a randomly selected sample of 7000 undergraduate students attending a large Midwestern research university in the United States. Sampled students were randomly assigned to a Web survey mode (n = 3500) or a mail survey mode (n = 3500). RESULTS: The majority of respondents experienced a secondary consequence of substance use in the past 12 months. Bivariate and multivariate results showed minimal differences between Web and mail survey modes in the reporting of secondary consequences associated with substance use. CONCLUSIONS: The present study provides evidence that Web surveys can be used as an effective mode for collecting data regarding secondary consequences among undergraduate college students. The present study suggests secondary consequences associated with substance use are highly prevalent among undergraduate students.

Adolescent↗
PubMed2006

Comparing web and mail responses in a mixed mode survey in college alcohol use research.

OBJECTIVE: This exploratory study examined potential mode effects (web versus U.S. mail) in a mixed mode design survey of alcohol use at eight U.S. colleges. METHODS: Randomly selected students from eight U.S. colleges were invited to participate in a self-administered survey on their alcohol use in the spring of 2002. Data were collected initially by web survey (n=2619) and non-responders to this mode were mailed a hardcopy survey (n=628). RESULTS: College students who were male, living on-campus and under 21 years of age were significantly more likely to complete the initial web survey. Multivariate analyses revealed few substantive differences between survey modality and alcohol use measures. CONCLUSIONS: The findings from this study provide preliminary evidence that web and mail surveys produce comparable estimates of alcohol use in a non-randomized mixed mode design. The results suggest that mixed mode survey designs could be effective at reaching certain college sub-populations and improving overall response rate while maintaining valid measurement of alcohol use. Web surveys are gaining popularity in survey research and more work is needed to examine whether these results can extend to web surveys generally or are specific to mixed mode designs.

Adolescent↗
PubMedDate not supplied

What do pediatric primary care providers think are important research questions? A perspective from PROS providers.

OBJECTIVE: To describe what pediatric primary care providers involved in the Pediatric Research in Office Settings (PROS) research network think are important yet inadequately addressed questions in pediatric primary care research. METHODS: A total of 1785 pediatric primary care providers in the PROS network were asked what they thought were important yet inadequately addressed areas of primary care research. We used a single, open-ended question in a mail survey. Written answers to this question were analyzed by qualitative methods to determine the main themes of interest to pediatric primary care providers. RESULTS: Overall survey response rate was 48.7%; the open-ended question yielded 1109 individual answers. Six lines of inquiry were identified as being important to these providers: (1) effective counseling techniques to use in anticipatory guidance; (2) strategies to prevent and treat obesity; (3) the effectiveness of well-child care; (4) ongoing management of patients with attention-deficit/hyperactivity disorder; (5) the role of the primary care provider in caring for children with mental health needs; and (6) optimal organization of office practices. CONCLUSIONS: The translation of research into practice may be improved by a better understanding of the needs and interests of those who see pediatric patients in the primary care setting.

Adult↗
PubMed2006

Complementing random-digit-dial telephone surveys with other approaches to collecting sensitive data.

Surveys of sensitive topics, such as the Injury Control and Risk Surveys (ICARIS) or the Behavioral Risk Factors Surveillance System (BRFSS), are often conducted by telephone using random-digit-dial (RDD) sampling methods. Although this method of data collection is relatively quick and inexpensive, it suffers from growing coverage problems and falling response rates. In this paper, several alternative methods of data collection are reviewed, including audio computer-assisted interviews as part of personal visit surveys, mail surveys, web surveys, and interactive voice response surveys. Their strengths and weaknesses are presented regarding coverage, nonresponse, and measurement issues, and compared with RDD telephone surveys. The feasibility of several mixed mode designs is discussed; none of them stands out as clearly the right choice for surveys on sensitive issues, which implies increased need for methodologic research.

Behavioral Risk Factor Surveillance System↗
PubMed2005

Impact of IRB requirements on a multicenter survey of prophylactic mastectomy outcomes.

OBJECTIVE: This study assesses the variability in requirements among six institutional review boards (IRBs) and the resulting protocol variations for a multicenter mailed survey. STUDY DESIGN AND SETTING: We utilized a cross-sectional mailed survey to gather information on long-term psychosocial outcomes of prophylactic mastectomy among women at six health maintenance organizations, all of which are part of the Cancer Research Network. In the context of this collaborative study, we characterized the impact of the different sites' IRB review processes on the study protocol and participation. RESULTS: IRB review resulted in site differences in physician consent prior to participant contact, invitation letter content and signatories, and incentive type. The review process required two to eight modifications beyond the initial application and resulted in unanticipated delays and costs. CONCLUSION: Site-to-site variability in IRB requirements may adversely impact scientific rigor and delay implementation of collaborative studies, especially when not considered in project planning. IRB review is an essential aspect of research but one that can present substantial challenges for multicenter studies.

Breast Neoplasms↗
PubMed2006

Match rate and positional accuracy of two geocoding methods for epidemiologic research.

PURPOSE: This study compares the match rate and positional accuracy of two geocoding methods: the popular geocoding tool in ArcGIS 9.1 and the Centrus GeoCoder for ArcGIS. METHODS: We first geocoded 11,016 Texas addresses in a case-control study using both methods and obtained the match rate of each method. We then randomly selected 200 addresses from those geocoded by using both methods and obtained geographic coordinates of the 200 addresses by using a global positioning system (GPS) device. Of the 200 addresses, 110 were case maternal residence addresses and 90 were control maternal residence addresses. These GPS-surveyed coordinates were used as the "true" coordinates to calculate positional errors of geocoded locations. We used Wilcoxon signed rank test to evaluate whether differences in positional errors from the two methods were statistically significantly different from zero. In addition, we calculated the sensitivity and specificity of the two methods for classifying maternal addresses within 1500 m of toxic release inventory facilities when distance is used as a proxy of exposure. RESULTS: The match rate of the Centrus GeoCoder was more than 10% greater than that of the geocoding tool in ArcGIS 9.1. Positional errors with the Centrus GeoCoder were less than those of the geocoding tool in ArcGIS 9.1, and this difference was statistically significant. Sensitivity and specificity of the two methods are similar. CONCLUSIONS: Centrus GeoCoder for ArcGIS for geocoding gives greater match rates than the geocoding tool in ArcGIS 9.1. Although the Centrus GeoCoder has better positional accuracy, both methods give similar results in classifying maternal addresses within 1500 m of toxic release inventory facilities when distance is used as a proxy of exposure.

Databases as Topic↗
PubMed2005

Small threat and contraband detection with TNA-based systems.

The detection of small threats, such as explosives, drugs, and chemical weapons, concealed or encased in surrounding material, is a major concern in areas from security checkpoints to UneXploded Ordnance (UXO) clearance. Techniques such as X-ray and trace detection are often ineffectual in these applications. Thermal neutron analysis (TNA) provides an effective method for detecting concealed threats. This paper shows the effectiveness of Ancore's SPEDS, based on TNA, in detecting concealed liquid threats and differentiating live from inert mortar shells.

Chemical Warfare↗
PubMed2005

A prospective study of the relationship between musculoskeletal or psychological complaints and muscular responses to standardized cognitive and motor tasks in a working population.

The present study sought to determine the relationship between musculoskeletal or psychological complaints and muscular responses to standardized cognitive and motor tasks. The prospective study design examined (i) whether complaint severity predicts muscular responses during standardized tasks and (ii) whether the muscular responses predict changes in complaint severity over one year. Musculoskeletal and psychological complaints were recorded by monthly reports the four months preceding and 12 months succeeding a work session in the laboratory; complaint-severity indices were computed from complaint-severity scores (intensity scorexduration score). Surface electromyography (EMG) was recorded bilaterally from the upper trapezius, middle deltoid, and forearm extensor muscles in 45 post-office workers (30 women) during two identical task series. Between the series, exhausting submaximal muscle contractions (25% of peak torque) were performed. In adjusted regression models, no relations between musculoskeletal complaints the last four months and muscle activity during the task series were found. However, psychological complaints the last four months predicted higher muscle activity levels and a steeper rise in muscle activity in the muscles not engaged in motor task performance. Sleep disturbance was the strongest individual predictor of increased muscle responses. In contrast, psychological complaints the last four months predicted lower EMG levels in the task-engaged muscle during the complex-choice-reaction-time tasks. None of the muscle-activity responses to the standardized tasks predicted changes in severity of musculoskeletal or psychological complaints over the subsequent one-year period. In conclusion, psychological complaints predict different responses in task-engaged and non-involved muscles during cognitive and motor tasks. Musculoskeletal complaints did not predict responses to the tasks.

Adult↗
PubMed2005

Application of hair-mercury analysis to determine the impact of a seafood advisory.

Following an official recommendation in the Faroe Islands that women should abstain from eating mercury-contaminated pilot whale meat, a survey was carried out to obtain information on dietary habits and hair samples for mercury analysis. A letter was sent to all 1180 women aged 26-30 years who resided within the Faroes, and the women were contacted again 1 year later. A total of 415 women responded to the first letter; the second letter resulted in 145 repeat hair samples and 125 new responses. Questionnaire results showed that Faroese women, on average, consumed whale meat for dinner only once every second month, but the frequency and meal size depended on the availability of whale in the community. The geometric mean hair-mercury concentration at the first survey was higher in districts with available whale than in those without (3.03 vs. 1.88 microg/g; P=0.001). The mercury concentration also depended on the frequency of whale meat dinners and on the consumption of dried whale meat. The 36 women who did not eat whale meat at all had a geometric mean hair-mercury concentration of 1.28 microg/g. At the time of the second survey, the geometric mean had decreased to 1.77 microg/g (P<0.001), although whale was now available in all districts. In comparison with previously published data on hair-mercury concentrations in pregnant Faroese women, these results document substantially lower exposures as well as a further decrease temporally associated with the issue of a stricter dietary advisory.

Adult↗
PubMed2005

Surgical management of stress urinary incontinence: a questionnaire based survey.

OBJECTIVES: To determine the trends in the surgical management of urinary stress incontinence amongst members of the International Urogynaecology Association (IUGA). DESIGN: Postal Questionnaire Survey. METHODS: 530 members of the International Urogynaecology association were sent a postal questionnaire regarding their practice in the surgical management of urinary stress incontinence. We also collected data on the demographic profile of members and the preferred primary and secondary continence procedures. OUTCOME: Consensus in the surgical management of urinary stress incontinence amongst members of the IUGA. RESULTS: Five hundred and thirty questionnaires were sent to IUGA members worldwide. Two hundred and seventeen questionnaires were received of which fifteen were from physiotherapists, so were excluded from our analysis. The overall response rate was 41%, and the useable response rate was 38%. Of the total results analysed (two hundred and two), one hundred and twelve (54%) were from teaching hospital, sixty-two (31%) were from district general hospitals and twenty-eight (14%) were from members in private practice. The preferred primary continence procedure was Tension Free Vaginal Tape (TVT) in one hundred and thirty four (68%) respondents. The preferred secondary continence procedure was colposuspension or Trans obturator tape in twenty-six respondents each (13%). CONCLUSIONS: Almost all respondents (97.1%) were skilled at performing either TVT or colposuspension, which have been identified as the preferred methods of surgical management by the NICE (National Institute of Clinical Excellence, UK). Although colposuspension has been identified as the gold standard surgical procedure in the management of stress incontinence, 16% of respondents were not performing colposuspension. There appears to be little evidence base to the surgical techniques in the management of stress urinary continence.

Adult↗
PubMed2005

Preimplantation sex selection demand and preferences in an infertility population.

OBJECTIVE: To determine the demand and preferences of infertility patients for sex selection and the method and sex they would choose, and to investigate the relationship between these choices and their demographic and socioeconomic characteristics. DESIGN: Cross-sectional survey. SETTING: University hospital-based fertility center. PATIENT(S): One thousand five hundred consecutive women who presented for infertility care. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Self-report questionnaire assessing the demand and preferences for sex selection. RESULT(S): Of respondents, 40.8% wanted to select the sex of their next child for no added cost. Of these patients, 45.9% had no living children and 48.4% had children all of one sex. After adjustment for observed predictors of gender preference, we found a significant preference for a female child among women who were older, not religious, willing to pay for sex selection, had more living children, had only sons, or had a diagnosis of male infertility. Nulliparous women did not significantly prefer one sex over the other. Among parous women, those with only daughters significantly desired to select a male child, whereas those with sons significantly desired to select a female child. In terms of the method of sex selection, 55.0%, 41.0%, and 4.0% of the patients would use sperm separation, preimplantation genetic diagnosis, or neither method, respectively. CONCLUSION(S): There is significant demand among infertility patients for preimplantation sex selection, with a significant portion of this demand coming from patients who do not have any children or have children all of one sex.

Adult↗
PubMed2005

Gender-related differences in general practice preferences: longitudinal evidence from the Netherlands 1982-2001.

The proportion of female doctors is increasing. Yet, there is little evidence that demonstrates changing career preferences over a long period, nor do we know the long-term impact of changing male-female ratios in medicine. We explored this within the GP profession. By means of a longitudinal cohort study (postal questionnaires) among all graduated GPs in the Netherlands between 1982 and 2001 we explored trends in career preferences and investigated whether practice preferences of men and women differ over the years. Preference of becoming a GP has significantly decreased among men. GPs prefer group practice more than solo practice. Female doctors were more likely to prefer a small practice and to associate. Men prefer to take over an established practice. Main reasons to abstain from practicing as a GP for men were having found another job or not having found a practice according to their preferences. Main reasons for women were having decided for another job and family life. We conclude that male and female GPs select differently on practice setting. Preferences change through the years but tend to converge. Gender differences are likely due to the circumstance that career choices for men are more influenced by fluctuating labour markets, while female choices are more based on family circumstances. We expect that as more women will become a GP the demand for small group practices will increase. Also, as many female GPs abstain from practicing after having finished a vocational GP training program it will be essential to create work facilities to keep them available for the GP labour market.

Adult↗
PubMed2006

Ethical issues in transnational "mail order" oocyte donation.

The rising demand for donor oocytes in developed countries has led to what is referred to as transnational or international oocyte donation, or the outsourcing of oocyte donation to poorer countries. In a further twist, frozen sperm from a recipient's partner can also be mailed to a foreign clinic to fertilize donor oocytes, and the resulting embryos are mailed back, cryopreserved, for transfer to the recipient. Among the numerous ethical concerns raised by this practice of mail order oocyte donation, the most obvious are that underprivileged women from poorer countries are often exploited; fertility physicians from richer counties abdicate responsibility for the welfare of donors; and responsibility could become an issue of contention if transmission of disease to the oocyte recipient or congenital defects in offspring born from such oocyte donation were to occur. Moreover, savings from utilizing donors from poorer countries ought to be shared with oocyte recipients.

Bioethics↗
PubMed2003

An investigation into low mail survey response rates of information technology users in health care organizations.

Surveys conducted by mail can result in a very low response rate raising the possibility of non-response bias that would question the validity of the findings. In this study, we compare the demographic profiles between the respondents and non-respondents, and conduct wave analysis as an alternative way to estimate the non-response bias among the information technology (IT) users in the health care industry. Our findings indicate that there is no significant difference among the respondents when considering the duration (early versus late) of response rate. Likewise, there was no significant difference when the available demographic characteristics (facility type and user's position) of those who responded were compared to the same characteristics of the sample. We were able to reach similar conclusion by using either of the proposed methods; analysis of demographic profiles of respondents versus non-respondents, and wave analysis. Thus our findings support the validity of the results from low response mail survey studies for IT users.

Community Participation↗
PubMed2004

The lack of a relationship between atopic dermatitis and nonmelanoma skin cancers.

BACKGROUND: Very little has been published on whether a relationship exists between atopic dermatitis (AD) and skin cancer. OBJECTIVE: The goal of this study was to investigate whether individuals with AD are more likely than other patients with dermatologic conditions to develop nonmelanoma skin cancer. METHODS: This was a case-control, mailed-survey study. RESULTS: Of those contacted, 69.8% (3207 of 4591) filled out the survey. Of the control patients, 18.4% (254) had a history of AD as defined by the United Kingdom Working Party diagnosis criteria and composed 13.7% (210) of the cases. The unadjusted odds ratio of AD to nonmelanoma skin cancer was 0.70 (95% confidence interval 0.57-0.85). After fully adjusting for age, sex, ethnicity, and topical steroid use the odds ratio was 0.78 (0.61, 0.98). Using different definitions of AD had little effect on this result. CONCLUSIONS: It does not appear that patients with a history of AD are more likely to develop nonmelanoma skin cancers than other patients with dermatologic conditions.

Aged↗