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[A case of a large pyelic calculus composed only of ammonium urate].

The authors report a case of pure ammonium urate stone. It was a very large lightly radiopaque pelvic stone, which was extracted by pyelotomy and analysed by infra-red spectrography. The clinical history did not reveal a long history of chronic infections. The stone was diagnosed by urography performed after an acute urinary trad infection. Proteus mirabilis was found at one time, but only after the surgical operation. The blood and urinary laboratory check-up was normal. No case of such a large pure ammonium urate stone especially in adults, can be found in the literature. The pathogenesis is not obvious, and could not be explained without an abnormal urinary ammonia production during the development of the stone, but the lack of associated phosphate precipitation cannot be explained.

Adult↗

[Bladder calculus formed on chromic suture].

This is a description of a clinical case of a two-and-a-half year old male child who developed a urinary bladder stone seeded on chromic catgut used to suture of the bladder wall which was damaged in the course of the surgical repair of an inguinal hernia.

Catgut↗

[Otogenic brain abscess with rupture into the lateral ventricle].

We present a case of otogenic abscess of the brain that ruptured into the ipsilateral cerebral ventricle. All the diagnostic, surgical and postoperative procedures which led not only to saving this patient but also his complete recovery are described. Because there is a great difference between rupture of a cerebral abscess into a ventricle and rupture of the ventricle into an abscess, particularly with reference to the prognosis, the pathology of the two different complications is reviewed, based on the literature.

Brain Abscess↗

[Hemagglutinating properties of Proteus mirabilis strains isolated from clinical specimens].

Haemagglutinating properties of 345 P. mirabilis strains isolated from various clinical samples were determined. Red blood cells of different origin as human group 0, bovine, horse, sheep and rat were used for the study. For the detection of MS and MR/P haemagglutinins the haemagglutination reaction was run with and without D-mannose. On the other hand, for the detection of type MR/K haemagglutinins tanned human and bovine erythrocytes were used. The majority of tested strains (90.14%) was polyhaemagglutinating i.e. showed simultaneously the presence of two or three haemagglutinins. Only three strains of P. mirabilis (0.87%) did not agglutinate any of the erythrocytes used for the study. The majority of strains (95.83-100%) in specific groups of clinical materials showed the presence of MR/K+ while MR/P+ 45.45-93.75% of strains and MS+ 45.83-73.1% of tested strains. Out of P. mirabilis strains isolated from urine, faeces and blood the highest percentage possessed at the same time all three haemagglutinin types (MS+, MR/K+, MR/P+) or pattern MR/K+, MR/P+. Bronchial isolates had usually pattern MR/K+ (31.82%) and strains isolated from skin possessed haemagglutinins of pattern MR/K+, MR/P+ (50%) and MS+, MR/K+, MR/P+ (43.75%). Among strains expressing MR/P+ at 37 degrees C a great differentiation of spectrum activity against tested erythrocytes was seen. Undoubtedly, the majority of MR/P+ strains from specific groups of clinical materials (with the exception of urine) agglutinated sheep and horse erythrocytes with and without D-mannose. The majority of strains isolated from urine agglutinated sheep and bovine erythrocytes.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Brain abscess as a cause of infant hydrocephalus. Case report.

The authors report on a case of hydrocephalus caused by brain abscess in a four-months-old girl. After repeated punctures and antibiotics administration extirpation of abscess was necessary. The child recovered with only slight neurological deficit.

Brain Abscess↗

The effects of low voltage current on healing of thermal third degree wounds.

Bilateral third degree burns were created on the flanks of eight miniature swine. Each animal had one side treated daily with low intensity direct (LIDC) of 400 microamperes (muA) by contact electrode for 2 hours morning and afternoon until healing occurred. The polarity of the electrode was negative in 4 pigs and positive in 4 pigs. One group of 4 pigs had the eschar surgically removed 24 hours post burn. Weekly biopsies and cultures were taken of treated and control wounds. Results indicated: local treatment of 400 muA LIDC did not hasten or delay healing of thermal third degree burns; escharectomy hastened wound healing by 10 days, and superficial proteus infection occurred in 80% of all wounds.

Animals↗

Lecithinase activity of Proteus vulgaris.

Lecithinase production is described as a new biochemical property of P. vulgaris strains grown in a selective agar medium containing brilliant green, crystal violet and lecithin (BCL agar), the authors' own modification of egg-yolk culture medium. By using this BCL agar as a medium inhibiting the swarming growth of P. vulgaris cultures the authors succeeded in identifying 12 lecithinase-positive strains among the P. vulgaris isolates obtained from patients with Crohn's disease. Of 50 P. mirabilis strains tested in parallel none gave the positive test for lecithinase production in this medium.

Crohn Disease↗

[Preventive properties of the blood sera from persons vaccinated with a Proteus vaccine made from soluble antigen complexes].

In experiments of the passive protection of mice the protective properties of sera obtained from humans before and after their immunization with Proteus vaccine used as a monopreparation or in combination with staphylococcal toxoid and/or pyoimmunogen were studied. When introduced in a single subcutaneous injection, Proteus vaccine prepared from soluble antigenic complexes ensured an increase in the protective properties of sera. The second injection of the vaccine essentially enhanced the protective potency of the sera of the immunized donors. The therapeutic injection of Proteus vaccine ensured the essential increase of the protective properties of the sera. This increase could be experimentally detected within at least 25-30 days from the beginning of immunization. The immunization of volunteers with Proteus vaccine in combination with pyoimmunogen and adsorbed staphylococcal toxoid ensured the maximum increase of the protective properties of their sera.

Animals↗

Cold injury in early infancy.

Sixteen cases of neonatal cold injury, five of them fatal, were seen in the winter of 1974-75. The affected infants, who weighed from 2.5 to 3 kg. had developed symptoms when the ambient termperature was below 10 C. Few of them were referred as cases of hypothermia. Refusal to eat was the most common complaint and less often edema and/or apathy. No correlation was found between death and ethnic origin, sex, duration of illness or minimum temperature. Admission weight, however, tended to be lower in the infants who died. The consistent finding of thrombocytopenia and the suspected bleeding phenomena suggested that disseminated intravascular coagulation may have been a factor in the unfavorable outcome of some of the cases. Evidence supporting such a hypothesis and proposals for the prevention. Diagnosis and treatment of neonatal cold injury are presented.

Body Temperature↗

[Experimental comparison of Maxon and chromic catgut in suturing of the urinary bladder].

The new monofile absorbable suture material Maxon was compared with Chromic catgut in bladder suturing in rabbits. Comparisons were made after 1, 2, 4, 8 and 12 weeks. The rate of stone formation was mainly determined by the suture technique used and not so much by the suture material. This was demonstrated by the low number of stones formed after using extramucosal suturing technique. Once a suture, be it Maxon or Chromic catgut, comes in contact with urine, concrements may form and the new monofile properties of Maxon do not offer any advantages here. On the other hand, Maxon does not enhance stone formation either. E. coli or Proteus infections did not influence formation of stones. The histological examinations showed Maxon to cause fewer inflammatory reactions. Sutures with Chromic catgut caused inflammation of the bladder wall, subsiding after 4 weeks. An existing urinary infection did not appear to influence the inflammatory process. Maxon offers an advantage over Chromic catgut in extramucosal sutures causing fewer inflammatory reactions.

Animals↗