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At least 487 records · Page 27Linked to original sources
PubMed2003

Vessel sealing using a pulsed bipolar system and open forceps.

We evaluated the vessel-sealing ability of one application of a pulsed plasma kinetic (PK) electrosurgical device on skeletonized vessels up to 7 mm in diameter to withstand sustained pressure of 300 mm Hg using bench and animal models. Forty-six porcine specimens and 66 abattoir vessels (112 total) were pressure tested after sealing with a pulsed PK system. Of these, 108 (96%) met the criterion of 300 mm Hg pressure held for 10 seconds without leaking. The PK system open forceps effectively closes vessels and maintains closure at a pressure level sufficient for clinical use. The device is more effective than clips, sutures, and staples.

Animals↗
PubMed1999

Molecular forceps from combinatorial libraries prevent the farnesylation of Ras by binding to its carboxyl terminus.

INTRODUCTION: Ras is one of the major oncogenes. In order to function properly it has to undergo post-translational processing at its carboxyl terminus. It has been shown that inhibitors of farnesyl transferase, the first enzyme in the processing chain, can suppress the transforming activity of oncogenic Ras. RESULTS: We have identified molecular forceps, branched peptidic molecules, from combinatorial libraries that bind to the carboxyl terminus of Ras and interfere with its farnesylation without inhibiting the farnesyl transferase. The active molecules were selected by a screening against the carboxy-terminal octapeptide of Ras. CONCLUSIONS: The implications of our findings are twofold. First, we demonstrate that it is possible to prevent enzymatic transformations by blocking the enzyme's access to its substrate using a synthetic small molecule to mask the substrate. Second, we show that it is feasible to derive molecules from combinatorial libraries that bind a specific epitope on a protein by selecting these molecules with the isolated peptide epitope.

Alkyl and Aryl Transferases↗
PubMed1991

Tracheo-oesophageal puncture without tears: the forceps technique.

Certain problems have been encountered using a rigid endoscopic technique for tracheo-oesophageal puncture in voice restoration following laryngectomy. An alternative method is described using a modified curved abdominal forceps which allows quicker and more predictable access to the puncture site.

Humans↗
PubMed2000

Percutaneous tracheostomy by forceps dilation: report of 162 cases.

A prospective, observational clinical study evaluated the safety of percutaneous single-step dilatational tracheostomy over a 43-month period. One hundred and sixty-two patients were deemed suitable for the procedure. The mean duration of tracheal intubation prior to tracheostomy was 6 days. The mean duration of the procedure was 9.3 min. Intra-operative complications occurred in 27 patients (16.6%), most of which were minor technical difficulties without morbidity. Postoperative complications, some of which were associated with morbidity, occurred in 16 patients. There were two deaths secondary to premature decannulation, one case of severe bleeding and five pneumothoraces. Long-term complications were assessed in 81 patients; there were four tracheal stenoses requiring surgery or laser therapy and seven patients with granulation tissue at the stoma site which did not require treatment. Forceps dilatational percutaneous tracheostomy appeared to be a convenient bedside procedure. However, complications do occur and further studies should address late sequellae, such as tracheal stenosis.

Adolescent↗
PubMed2002

Endoscopic removal of intravesical thermometer using a rigid nephroscope and forceps.

Intravesical thermometers are occasionally encountered in urologic practice. In the present paper, we describe the removal of a thermometer from the bladder of a woman who presented with irritable bladder symptoms. The thermometer was removed intact transurethrally using a rigid nephroscope and forceps, even though both ends of the thermometer were embedded in the bladder wall. Our retrieval technique may be of general use in such cases, and it should be attempted before resorting to open surgery.

Adult↗
PubMed2002

Computerized bipolar diathermy with scissors and forceps in cutaneous surgery.

BACKGROUND: Bipolar diathermy coagulates tissue as effectively as monopolar with less lateral tissue injury and no risk of interference with cardiac pacemakers or joint prostheses. OBJECTIVE: To test a novel computerized bipolar diathermy machine for combined cutting and coagulation in dermatologic surgery. METHODS: A divided cable was used to deliver current from a computerized bipolar diathermy unit to both scissors and forceps. The bipolar diathermy unit senses tissue contact with the instruments and starts automatically; a built-in microcomputer measures tissue impedance and automatically terminates the current when tissue coagulation is achieved. RESULTS: The equipment has been used successfully in more than 200 patients undergoing dermatologic surgery. The advantages were a reduced operating time and a more secure hemostasis. The microprocessor controlled bipolar diathermy unit minimized any tissue adherence to the instruments during use. CONCLUSION: We recommend the use of insulated scissors and computerized bipolar diathermy for safe and efficacious coagulation and cutting in dermatologic surgery.

Dermatologic Surgical Procedures↗
PubMed2003

Magill forceps extraction of upper esophageal coins.

BACKGROUND/PURPOSE: This study demonstrates a minimally invasive technique for upper esophageal coin extraction. METHODS: A retrospective review was conducted of 36 children who had upper esophageal coins extracted using a Magill forceps. RESULTS: All coins were removed without complication in approximately 45 seconds (33 on the first attempt, 3 on the second attempt). CONCLUSIONS: This technique minimizes instrumentation of the esophagus and is highly successful at removing coins lodged at or immediately below the level of the cricipharyngeus muscle.

Child, Preschool↗
PubMed2001

A novel approach to endoscopic colorectal mucosal resection using a three-channel outer tube and multiple forceps: an experimental assessment.

BACKGROUND AND STUDY AIMS: Colorectal endoscopic mucosal resection (EMR) has limitations both anatomically and technically when it is done using the conventional snare wire method. The aim of this study was to develop a new method and instrument for colorectal EMR. METHODS: A total of 21 EMR procedures were done using ten surgical specimens. Saline was injected into the normal submucosa of freshly resected colorectal specimens to prepare a pseudotumor. EMR was performed experimentally by employing a three-channel outer tube with three forceps and a colonoscope with a needle-type precutting knife. This method was assessed in terms of safety and the size of the resected specimens. RESULTS: Perforation occurred only twice in the initial stage of this study. The size of the specimens resected by EMR was 28-39 mm (long diameter 34.8+/-3.11), by 22-28 mm (short diameter 25.8+/-2.07). CONCLUSION: This method can achieve safety and en bloc mucosal resection to the submucosal layer. This novel approach may be promising for clinical application as a new form of endoscopic surgery.

Colonoscopes↗
PubMedDate not supplied

Yield of bronchial forceps biopsies in addition to nasal brushing for ciliary function analyses in children.

BACKGROUND: The diagnosis of primary ciliary dyskinesia (PCD) is unlikely, if ciliary beat frequency (CBF) is normal. The aim of this study was to test the diagnostic value of an additional bronchial biopsy in cases where nasal CBF are abnormal. PATIENTS, METHODS: In a paediatric bronchitis population nasal brush biopsies and bronchial forceps biopsies were taken. In both samples we measured CBF and compared results to nasal CBF of infants and children without respiratory disease. RESULTS: Patients with bronchitis (n = 31; 0.3 to 14.6 years; 10 girls) had a normal CBF in their nasal biopsies in 68 %, and in bronchial biopsies in 48 %, compared to the reference group (n = 72; 0.5 to 17.5 years; 23 girls). One patient had an abnormal nasal, but a normal bronchial ciliary activity. When cilia were beating at both sites (n = 14), nasal CBF agreed well with bronchial CBF (mean difference -0.78 Hz, 95 % confidence interval -1.81 Hz to 0.25 Hz). CONCLUSIONS: By adding the investigation of bronchial mucosa to the measurement of nasal CBF the diagnostic yield to exclude PCD was only improved from 68 % to 71 %. Consequently, if nasal ciliary activity is abnormal in infants and children with bronchitis, we do not recommend additional bronchoscopy to obtain another biopsy.

Adolescent↗
PubMed1980

Forceps biopsy of the bile duct under choledochoscopic control.

Forceps biopsy of the distal part of the common bile duct was performed in 27 patients with cholelithiasis, under choledochoscopic guidance during surgery. Significant choledochitis was diagnosed in 72 per cent of the patients, including two with carcinoma of the head of the pancreas. Two patients with carcinoma of the head of the pancreas underwent biopsy in an attempt to obtain evidence of neoplasm. Furthermore, one patient suspected of carcinoma of the left hepatic duct tributaries received the same treatment and the malignancy was confirmed. No complications occurred. The prime indication for biopsy is to prove the presence of malignancy at this region and to provide an index for the management of cholangitis combined with choledocholitiasis.

Adenocarcinoma, Papillary↗
PubMed1995

[An unusual case: vaginal foreign body (forceps) as an incidental finding during primary operation for breast cancer].

A 29 year-old patient was admitted for surgery because of two breast lumps. One of these was suspicious for malignancy by a mammogram and palpation. When her history was taken, the patient mentioned putrid vaginal discharge and denied any previous gynaecologic examination. After initial hesitancy, the patient agreed to have a pelvic examination. This revealed an oxydized iron rod protruding 2 cm out of the vagina. The object was identified by x-ray examination as one handle of iron forceps often used for cutting metal wires. The patient had been carrying this foreign body for fifteen years. She was not willing to relate any information about the cause of the manipulation or any eventual culprit. She was consistent and her personality was dominated by introverted behaviour. The foreign body was removed under the same anaesthesia as that used for the operation on the breast cancer.

Adult↗
PubMed2001

Successful en bloc resection of a large superficial gastric cancer by using sodium hyaluronate and electrocautery incision forceps.

BACKGROUND: The advisability of endoscopic mucosal resection (EMR) for treatment of large superficial gastric cancers has been challenged. For more reliable en bloc resection, a new method of EMR was developed that uses a viscous substance, sodium hyaluronate, and two newly designed devices. METHODS: A large superficial gastric cancer was treated with this new EMR technique. Sodium hyaluronate was injected into the submucosa and mucosal incisions were made with a needle-knife. The newly developed incision forceps and flat-ended transparent hood were used for submucosal incisions. RESULTS: The large cancer was successfully resected endoscopically as a single piece of mucosa 6 cm in diameter without complication. Histopathologic evaluation of the specimen confirmed that the resection was curative. CONCLUSIONS: EMR with sodium hyaluronate along with two new devices may be a reliable method for en bloc resection of large superficial gastric lesions.

Aged↗
PubMed2003

A new tumour forceps for use during removal of pineal region tumours.

A new forceps for grasping and cutting tumour in a narrow surgical field is described. The working length is 12 cm and the grasping element at the tip is 1 mm in diameter. To avoid damage to surrounding structures caused by pulling out the tumour, the grasping portion consists of two hollow cylinders with sharp edges that divides, rather than tears tissue.

Brain Neoplasms↗
PubMed2001

New ergonomic design criteria for handles of laparoscopic dissection forceps.

BACKGROUND: The shape of laparoscopic instrument handles can cause physical discomfort. This problem may be ascribed to a lack of standards for instrument design. In this study, new ergonomic requirements for the design of laparoscopic dissection forceps were created. Three representative handles (a Karl Storz [click-line] scissors handle, an Access Plus scissors handle, and an Aesculap cylindrical handle) currently available on the market were evaluated according to the new list of ergonomic criteria. MATERIALS AND METHODS: The handles were subjectively (questionnaire) and objectively (video analyses) tested in order to find out whether the new requirements are valid for the evaluation and design of instrument handles. RESULTS: The outcome of the subjective and objective tests matched the predictions by the new criteria list. New criteria were introduced (neutral wrist excursions), and existing general criteria were specified (e.g., a minimal contact area of 10 mm). Significant differences were found among the three handles. The Storz handle met 8 of the 10 requirements, the Access handle met 5, and the Aesculap handle met only 4. CONCLUSIONS: The new list of ergonomic requirements is a valid tool to determine the ergonomic value of a handle for laparoscopic dissecting tasks. It gains its strength from its specialized character. Significant differences were found among the three tested handles. Cylindrical handles were inferior to scissors handles.

Dissection↗
PubMed1997

Using 5-mm bipolar cutting forceps: a new multifunctional instrument.

The most technically challenging step in performance of esophagogastric fundoplication is division of the short gastric vessels that connect the splenic hilum to the gastric fundus. Consistent dependable coagulation and division of these vessels would be a significant advance that would make the procedure more widely available to patients, since it would provide surgeons with a safe technique for providing a reliable loose "wrap." Such an instrument has now become available and is called the "bipolar cutting forceps." One of the authors has recently used the tool (5-mm version) for the laparoscopic completion of five Toupet fundoplications and two gastrojejunostomies. The instrument functioned in both the locked and manual mode and provided effective bipolar coagulation and scalpel division of thick lesser curve and greater omental tissue. No bleeding was noted, and all procedures were completed without conversion to laparotomy. The notion that such a multifunctional instrument will lead to cost reductions is possible but yet unproven.

Electrocoagulation↗
PubMed1984

Hooked forceps.

A combined hooked forceps is presented which may be very useful for procedures performed without assistance.

Equipment Design↗
PubMedDate not supplied

Reprocessing of single-use endoscopic biopsy forceps and snares. One hospital's study.

Financial pressures imposed on hospitals by health maintenance organizations and insurers have prompted investigation into alternative procedures that reduce expenses while maintaining the high standards required for patient care. Although not necessarily mutually exclusive, these dual agendas pose a challenge for endoscopy managers charged with balancing the risks and benefits of reusable and disposable endoscopy instruments. Our endoscopy unit elected to evaluate the feasibility of reducing costs by using reprocessed single-use devices. Following the selection of a third party reprocessor and prior to using any reprocessed devices in the clinical setting, our facility decided to submit single use devices that had been used once for reprocessing and then have an independent laboratory test them for sterility. Although we followed a thorough, multi-disciplinary approach, our end result led us to conclude that the cleaning, reprocessing, and resterilization of single-use biopsy forceps and snares is a greater challenge than previously anticipated. Reprocessing of the single-use devices tested did not result in endoscopic instruments that met acceptable standards for sterility at our institution.

Alabama↗