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Ossifying fibroma.

Our experience includes seven cases of ossifying fibroma. The condition also appears in the literature under diagnostic names such as congenital fibrous dysplasia, congenital osteitis fibrosa, congenital fibrous defect of the tibia, and osteofibrous dysplasia of the tibia and fibula. The lesions develop in childhood and are located in the diaphysis of the tibia, or fibula. Of seven patients, we performed wide excision with free vascularized fibular graft in five cases, wide resection of the distal one-third of the fibula in one case, and curettage and bone graft in one case. Two of the patients who had wide excision with free vascularized fibular graft had recurrence. One case of recurrence occurred where incomplete wide excision with free-vascularized fibular graft was performed because the lesion was too close to the distal epiphysis of the tibia. One of the patients who had curettage and bone graft also had recurrence. It was concluded that children who have an ossifying fibroma requiring surgery can safely be treated with wide excision with or without free-vascularized fibular graft.

Adolescent↗

Desmoplastic fibroma of the frontal bone.

Desmoplastic fibroma is a benign but locally aggressive tumor arising usually from the mandible, pelvis and long bones with a potential for recurrence. We report a case of desmoplastic fibroma of the frontal bone in a young male.

Actins↗

Non-functioning ovarian fibroma with extensive calcification: case report.

A case of a non-functioning ovarian fibroma with extensive calcification in a young Ugandan female is described. Ovarian fibromas occasionally may be bilateral and associated with benign ascites and pleural effusion called Meigs' syndrome or related to a rare hereditary condition known as Gorlin's syndrome. Rarely if functioning, the tumour may produce hormones to cause diabetes mellitus or hypoglycaemia or secrete carbohydrate antigen 125 to clinically simulate ovarian carcinoma.

Adult↗

Testicular fibroma of gonadal stromal origin with minor sex cord elements: clinicopathologic and immunohistochemical study of 2 cases.

OBJECTIVE: To report the histologic and immunohistochemical features of 2 cases of intratesticular fibromatous tumors. RESULTS: Microscopically, these tumors were composed of short, randomly interweaving fascicles of spindle cells dispersed within a fibrocollagenous stroma. A sex cord component was detected in one case by microscopic examination and in both cases by immunohistochemical study using MIC2 and anti-inhibin antibodies. CONCLUSIONS: The presence of minor sex cord elements, morphologically or by immunohistochemistry, suggests that these fibromatous tumors are related to and are a subset of sex cord-stromal tumors. Intratesticular fibromatous tumors, of which 11 other cases lacking sex cord elements have been reported, could be considered as the testicular equivalent of ovarian fibroma. These tumors could then be referred to as testicular fibroma of gonadal stromal origin, with or without minor sex cord component.

Adolescent↗

Nonossifying fibroma. Four cases and review of the literature.

Nonossifying fibroma is a benign, lytic lesion that occurs in young children and adolescents. Radiographically, the lesion is multilocular and sharply demarcated. It often occurs at the metaphyseal region of long bones of the lower extremity and is usually eccentrically located. Four cases of nonossifying fibroma occurring during the past 7 years are presented with a review of the literature.

Adolescent↗

[Cardiac fibroma: a successfully operated case and a review of the literature (author's transl)].

A case of cardiac fibroma in a three years old child successfully operated on is presented. The tumor was localized on the interventricular septum and was provoking an obstacle in the outflow of the right ventricle. The preoperative diagnosis was formulated by angiocardiography. A year after the operation, the hemodynamic control showed that he interventricular pressures were normal. The problems and the importance of an early diagnosis are emphasized in patients affected by cardiac fibroma. Surgical indication, technical aspects related to the operation, the immediate and more long-term results from surgical operation of this kind of pathology, with reference to the data taken from the literature, are discussed.

Angiocardiography↗

Large ovarian cellular fibroma during pregnancy mimicking a lipid cell tumor.

Lipid cell tumors are extremely rare tumors of the ovary which are usually malignant when larger than eight centimeters. Fibromas, on the other hand, are the most common type of benign ovarian solid tumors. Neither one of these tumors are known to be accelerated by the pregnant state. We report a case of a healthy 15-year-old female who was found to have an ovarian mass during pregnancy. This fibroma weighed more than 3,800 grams and mimicked a lipid cell tumor. Cesarean section and unilateral oophorectomy resulted in a good outcome for both mother and child.

Adenocarcinoma↗

Giant central ossifying fibroma of the mandible: report of case.

A case is presented of a patient with a giant ossifying fibroma of the mandible that had been diagnosed earlier as fibrous dysplasia. Surgical resection of the tumor and involved bone was chosen as the mode of treatment because of the extent of the lesion and continued infection. Surgeons should be aware that ossifying fibroma is a very distinct possibility in large growing lesions in age groups older than is deemed compatible with fibrous dysplasia.

Diagnosis, Differential↗

Cemento-ossifying fibroma and benign cementoblastoma.

Cementum is a calcified dental tissue that covers the roots of teeth and is part of the periodontium. Its function is to help anchor the teeth in their sockets within the alveolar bone of the jaws. Two benign mesenchymal odontogenic tumors are uniquely distinguished by elaboration of cementum or cementum-like material: cemento-ossifying fibroma and benign cementoblastoma (true cementoma). Cemento-ossifying fibroma, which is also termed periodontoma, is characterized by production of cementum and bone in a fibrous stroma. It is a painless, slow-growing tumor usually detected in the third and fourth decade of life and is more common in women. The mandible is its site of predilection. Benign cementoblastoma is intimately associated with the roots of teeth, most commonly mandibular molars. It affects young patients, usually under the age of 20 years. Pain is a common symptom in addition to bone expansion. Benign cementoblastoma bears considerable histologic resemblance to osteoblastoma.

Adolescent↗

[Osseous desmoid fibroma of the mandible, a propos of 1 case].

Osseous desmoid fibromas, analagous with soft tissue desmoid fibromas, are rare tumors with exceptional localization in the mandible, revealed by: -tumefaction and trismus in usually very young subjects; -the radiological picture is that of lysis with relatively well defined limits, but with no double outline, with possible cortical rupture and aberrant lacunae far from the main focus which explains possible recurrences of this tumor which is nevertheless benign. The main histological danger is confusion with a differenciated fibrosarcoma. Mandibular resection which is frequently necessary should ensure stable recovery.

Adult↗

[Cemented fibroma of the maxillary sinus].

Cementifying fibroma is a benign fibro-osseous lesion with dental origin. We describe a case of cementifying fibroma of the maxillary sinus, an unusual location for this tumor.

Adult↗

Aggressive ossifying fibroma of the maxilla: review of the literature and report of case.

A case of a large aggressive ossifying fibroma of the maxilla has been presented. Review of the literature shows the literature shows the difficulty in establishing a definitive diagnosis through any single diagnostic modality. Much of this is due to the confusion surrounding classification of the tumor. Adjunctive radiographic and nuclear medicine diagnostic aids were utilized, as were clinical, laboratory, and histopathologic studies, in resolving the diagnostic questions posed by this large and aggressive tumor. Surgical intervention through conservative enucleation produced few operative or postoperative difficulties and minimal residual deformity. Differentiation of ossifying fibroma from other benigh and malignant neoplasms as well as fibrous dysplasia is important in the correct management of this lesion.

Adolescent↗

Fibroma of tendon sheath involving the patellar tendon.

Fibroma of tendon sheath is a benign soft-tissue tumor that usually arises in association with tendons or ligamentous structures. We describe, what is, to the best of our knowledge, the first reported case of fibroma of tendon sheath involving the patellar tendon.

Adult↗

[Unusual case of calcified renal fibroma].

The renal fibroma is an extremely rare event that takes its origin from parenchima, from the peri-renal tissues or from the renal capsule. A case of renal fibroma of a rarely met medullary origin is described.

Adult↗

[Left ventricular reconstruction after excision of a large fibroma].

The authors report the case of a 15 year old boy with a large left ventricular fibroma discovered after a series of syncopal episodes due to obstruction to ejection. The first attempt to remove the fibroma in Columbia was only partially successful. In view of the risk of death associated with this type of tumour, it was decided to offer the patient complete excision after a full morphological and functional evaluation of myocardial function and the consequences of the tumour on mitral valve function and on the coronary circulation. The operation was performed under cardiopulmonary bypass and aortic clamping by conventional surgery, associated with reconstruction of the cardiac free wall with a large patch of autologous pericardium which was necessary to avoid cardiac transplantation, the ultimate sanction in this indication.

Adolescent↗

Calcified intramural fibroma of the left ventricle.

A calcified intramural fibroma of the left ventricle in a 20-yr-old patient with a severe chest pain was studied. The chest film showed a cardiac silhouette with a prominent left border, and a large calcification inside. Surgical removal was impossible. The histological examination demonstrated a typical fibroma.

Adolescent↗

[Solitary pleural fibroma: report of two cases and review of the literature].

The pleural fibroma is an uncommon tumor of pleura. Its Diagnosis is guided by chest imaging and confirmed by surgery and histological exam. We respectively report two observations of solitary pleural fibroma in 68 and 27 old years patients. The authors expose the circumstances of discovery and present clinical features, diagnosis explorations and therapeutical methods. Prognosis depends primary on histological findings and malignant recurrences are possible.

Adult↗

Acute abdomen due to torsion of a pedunculated mesenteric fibroma.

A case history of a boy with an acute abdomen due to torsion of a pedunculated mesenteric fibroma is presented. A review of the literature shows that only a relatively small number of mesenteric fibromata have been reported. In these cases the tumor was described as growing between the two leaves of the mesentery. The symptoms these tumors gave usually were due to the size of the tumor and compression of adjacent organs. The present case is unusual because of the pedunculated nature of the fibroma and its presentation as an acute abdomen.

Abdomen, Acute↗