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[Role of the genes in odontogenesis].

The authors suggest a genetic model of dental development. This model is based on chromosomal mapping of genes involved in odontogenesis. The role of X and Y chromosomes is updated.

Chromosome Aberrations↗

Phenomenological model of creep of dental amalgam.

Earlier work revealed that creep of a particular dental amalgam can be described by the model F(t) = F0 exp (t/t0)m. Here F(t) is the creep compliance at time t, whereas F0, t0 and m are constants of the model. In the previous study only three alloys were used. It was the aim of this study to investigate the factor alloy more thoroughly. After specimen preparation, the nineteen different amalgams were aged at 37 degrees C for either one day or one week. Then creep was determined at a temperature of 22.5 degrees C and a compressive stress of 117 MN/m2. F0 turns out to depend upon both the ageing time as well as on the choice of the alloy. As expected, t0 shows up substantial differences between the respective amalgams, whereas the differences between the two ageing are absent or relatively small. The factor alloy significantly influences m. However, the ageing time exerts no significant influence upon m.

Chemical Phenomena↗

A sociodental approach to assessing dental needs of children: concept and models.

OBJECTIVES: Traditional normative methods of assessing dental needs do not correspond to current concepts of 'health' and 'need'. Although there is dental research on quality of life, evidence-based practice, and oral behaviours, those concepts are rarely applied to dental needs estimation. Dental needs are usually calculated mainly from clinical data and are likely to be inaccurate. A structured comprehensive method for assessing dental needs is required. The objectives of this study are to develop and test a new sociodental system of needs assessment for overall dental needs of primary schoolchildren. Furthermore, normative and sociodental estimates of need are compared. DESIGN: The study developed a theoretical framework and pathway algorithms of sociodental needs assessment and applied them to assessing overall dental needs. Normative dental needs were assessed using standard normative criteria. The child oral impacts on daily performances (Child-OIDP) was used to assess oral impacts, and a self-administered questionnaire was used to obtain information on demographic variables and oral behaviours. Data were analysed according to the developed algorithms. SETTING: A cross-sectional survey in Suphanburi Province, Thailand. PARTICIPANTS: All 1,126 children aged 11-12 years in a town. MAIN RESULTS: The sociodental approach was acceptable and not costly. In all, 54.4% had normative need under the dental needs model for life-threatening and progressive conditions, but only 16.6% had high propensity-related need; the remaining 37.8% would require dental health education or oral health promotion (DHE/OHP) or both and appropriately adjusted clinical interventions. Under the basic model of dental needs, 45.1% had normative need. Two-thirds of them (30.9%) had impact-related need and the remaining 14.2% did not have oral impacts and therefore should only receive dental health education. Only one-third of those with impact-related need had high propensity and were suitable for evidence-based conventional treatments; the remaining two-thirds should receive DHE/OHP and alternative clinical interventions. CONCLUSIONS: A sociodental system of dental needs assessment was developed and tested on school children. It decreased the estimates of conventionally assessed dental treatment needs and introduced a broader approach to care.

Algorithms↗

The holographic storage of study models.

The storage and recall of dental study models pose major problems for orthodontists. This problem may be solved by taking holographic films of study models. A method is described for their fabrication and some preliminary measurements are reported. The image produced by this method has a measurable three-dimensionality which can be produced at a very reasonable cost.

Dental Records↗

Supernumerary molars in Anthropoidea, Adapidae, and Archaeolemur: implications for primate dental homologies.

The model of primate dental homologies and development recently proposed by Schwartz ('75, '78) is re-evaluated in view of documented exceptions to his account of postcanine supernumerary teeth in both anthropoids and prosimians. Schwartz concluded that catarrhines and living indriids retain only two true molars in each dental quadrant. As many as six molars on one side of the jaw can develop in rare instances in catarrhines, and supernumerary molars are also known for a wide range of other primates, including Cebidae, Adapidae, and subfossil Indriidae. Polydontia cannot be explained exclusively by atavistic development. More convincing explanations regard supernumerary teeth as the result of excessive growth of the dental lamina or localized twinning of tooth buds during early development. Conventional dental formulae of catarrhines and indriids including three permanent molars remain the most plausible.

Animals↗

Nociceptive behaviour induced by dental application of irritants to rat incisors: a new model for tooth inflammatory pain.

Animal models simulating acute human pulpitis are still lacking. The rat incisors present a particular situation where most of their innervation is considered to be unmyelinated and concentrated mainly in the tooth pulp. This study reports on a new model for dental pain induced by inflammatory agents applied to the tooth pulps of incisors. In different groups of rats, artificial crowns were fixed on the lower incisors, after cutting 1-2mm of their distal extremities. A volume of 7-10 microl of solutions of saline, capsaicin (1-10mg/ml) or formalin (2.5% or 5%) was injected in the crown cavity, and the nociceptive behaviour was quantitated following a devised scoring method of four scales. Intradental application of capsaicin produced nociceptive scores in the form of one plateau for 1-2h depending on the concentration used. Similar results were obtained with intradental application of formalin 2.5%. The one plateau of nociceptive scores obtained with formalin contrasts with the biphasic aspect of nociceptive behaviour described with the intradermal formalin test. This discrepancy could be attributed to a difference in the types of afferent fibres involved in each situation. Pretreatment with morphine (2 mg/kg) attenuated, in a naloxone-reversible manner, the nociceptive behaviour observed following intradental application of capsaicin. Pretreatment with meloxicam (a cyclo-oxygenase-2 inhibitor) exerted a less pronounced attenuation of the nociceptive scores when compared with morphine. These results provide evidence for the validity of the described model for the simulation of tooth pulp inflammatory pain in awake animals.

Analgesics, Opioid↗