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State of the art in the treatment of gastric cancer: from the 71st Japanese Gastric Cancer Congress.

The recent literatures has few reports of the state of the art and latest results in the treatment of gastric cancer, although such information is necessary for conducting new clinical trials and for obtaining informed consent from patients. In the panel discussions at the 71st Gastric Cancer Congress of Japan (held in Tokyo, June 1999), 18 representative institutions and hospitals in Japan reported their latest results for the surgical treatment of gastric cancer, indicating the state of the art in the treatment of gastric cancer. Here we report a summary of these sessions.

Journal Article↗

Opening remarks SIVB congress 2001: opportunities and challenges in plant biotechnology.

U.S. Senator Christopher Bond joined Dr. Roger Beachy at the podium during the Society for In Vitro Biology's 2001 Congress Plenary Session on Opportunities and Challenges in Plant Biotechnology to Benefit Health and Sustainability, on June 17, 2001, in St. Louis, Missouri. Senator Bond presented an advocate's view regarding the benefits of plant biotechnology development. The strengths of the biotechnology regulatory system were extolled. The opportunities of this new technology to produce more and nutritionally superior food, additional plant-based medicines and vaccines, plant-based renewable sources of energy, and renewable industrial products were outlined. The benefits to the environment by adopting plant biotechnological innovations were discussed. Developing public policy regarding this new technology should be based on facts, science, and reason.

Biotechnology↗

The European Congress on Cobalt and Hard Metal Disease. Conclusions, highlights and need of future studies.

This article summarizes the present state of the art and some recommendations for solutions to problems identified by the European Congress on Cobalt and Hard Metal Disease on the basis of the papers and posters presented, as well as a round table discussion which produced several dominant questions and revealed areas of weakness and uncertainty. The round table discussion (chairman, Professor E. Capodaglio) focussed on the following aspects: (i) Monitoring (opinion leaders: R. Lauwerys, E. Sabbioni). (ii) Mechanisms of toxicity (opinion leaders: B. Nemery, N.L. Sprince, G. Scansetti). (iii) Health effects (opinion leaders: G. Nordberg, I.B. Andersen). (iv) Diagnosis/health surveillance (opinion leaders: G. Chiappino, S. Hernberg, S. Brown).

Cobalt↗

Congress objectives.

In 1993, the Viral Hepatitis Prevention Board (VHPB) recognized that selective vaccination of individuals at high risk from hepatitis B had failed to control the spread of hepatitis B. The Action towards Control of Hepatitis B as a Community Health Risk was therefore established to provide information and make recommendations on actions to take to combat hepatitis B in the community. The VHPB supports the World Health Organization (WHO) recommendation that universal hepatitis B vaccination for all infants and/or adolescents should be integrated into the national immunization programme in all countries by 1997. The VHPB met regularly throughout 1993 to consider the issues involved in implementing universal strategies and to develop practical solutions that can help all countries meet the WHO goal. During this congress the feasibility of implementing universal infant and/or adolescent vaccination strategies were explored by reviewing the seroprevalence data in Europe, development of cost-benefit models and progress in countries that have already implemented universal vaccination. With the delegates' input, resolutions were reached that will guide future action towards meeting the WHO goal and combating hepatitis B in the community.

Hepatitis B↗

A spatial analysis of voting on health care issues. United States House of Representatives, 86th Congress, First Session.

This study examines the spatial patterns of congressional voting on health issues. Thirteen roll call votes on health care issues occurring during the 1st Session of the 96th Congress are factor analyzed. This analysis shows that health care questions cluster around two major issues: health care regulation and health care spending. The factor scores for each Representative are mapped, and a regression model is developed relating health care voting to characteristics of the Representative, the Congressional district, and the hospitals in that district. The most important findings were: (1) support for both health care spending and regulation is strongest in the Northeast and upper Midwest. (2) Although Representatives from most of the Southern states are opposed to health care regulation, they generally favor health care spending. (3) Representatives from a few of the Southern states, however, do not fit this generalization. (4) Although Representatives from the Pacific Coast states are the strongest proponents of regulation, they are opposed to spending (5) Opposition to health care spending is particularly strong among Representatives from suburban districts.

Cost Control↗

Guidelines and policies on collection of biological specimens in the Philippines. Philippine Congress, International Convention on Biodiversity.

In October, 1993, 16 months after the United Nations approved the International Convention on Biodiversity held in Rio de Janeiro, June, 1992, the Philippine Congress ratified and adopted the Convention. This is a manifestation of the full support of the Philippines for the principles and policies adopted by the UN body on the conservation of biodiversity, sustainable development of biological resources and equitable sharing of benefits between users and owners of biodiversity resources. The Philippine scientific community has long recognized the need for and importance of a national guideline and policy with regard to the collection of plants and animals in the Philippines for scientific or commercial purposes. A series of consultative meetings were held by representatives of government agencies, non-government organizations, private organizations, academic and private persons concerned with biodiversity conservation to formulate national guidelines that regulate the collection of plant and animal specimens in the country. Guidelines were unanimously adopted by various government agencies and academia and a Memorandum of Agreement (MOA) was signed on September 28, 1990. Very recently a new document was drafted, specifically to serve as a guideline for those who desire to undertake sample collecting in the Philippines for biodiversity prospecting. The document is now being reviewed by government departments and agencies and will be presented to the President of the Philippines for signing as an Executive Order (EO). Once signed, this EO will serve as a national policy for bioprospecting in the country. The Philippines is one of the countries in Southeast Asia that has endorsed the adoption of regional guidelines on the collection of plant and animal organisms for drug development. The ASEAN Agreement on the Conservation of Nature and Natural Resources (1985). The Manila Declaration (1992) and lately, the Melaka Accord (1994), all of which were signed by various countries in Asia, are manifestations of this interest.

Ethics↗

Patient Education 2000: take-home messages from this congress.

A personal review is presented about the conclusions and highlights during the Congress on Patient Education 2000 (14 June 1994, Geneva, Switzerland). Attention is paid to differences between diseases concerning patient education. Further, a summary is presented of the discussion of quality of life, over-optimism, medical information supply, purpose of patient education, the need for discipline and the psychological problems due to wrong patient education.

Adaptation, Psychological↗

An overview of schizophrenia genetic research presented at the 1995 World Congress on Psychiatric Genetics, Cardiff.

The 1995 World Congress on Psychiatric Genetics was held in Cardiff, UK, from August 29th to September 1st 1995. Two hundred and forty-seven posters were presented wherein approximately 130 studies were on schizophrenia. An overview of them is reported here. The abstracts of these studies are published in Psychiatric Genetics (vol. 5, suppl. 1, 1995).

Chromosomes, Human, Pair 22↗

Clinical trials update from the joint European Society and World Congress of Cardiology meeting: PEP-CHF, ACCLAIM and the HHH study.

This article provides information and a commentary on trials relevant to the pathophysiology, prevention and treatment of heart failure, presented at the joint European Society and World Congress of Cardiology meeting held in Barcelona in September 2006. All reports should be considered as preliminary data, as analyses may change in the final publication. The PEP-CHF study suggests that perindopril improves symptoms and functional capacity and may reduce heart failure hospitalisations in patients with diastolic heart failure. Although immune modulation therapy failed to reduce the incidence of all-cause mortality and cardiovascular hospitalisations in the ACCLAIM study, the observed differences in outcome in some heart failure patients warrants further investigation. The HHH study failed to show a beneficial effect of telemonitoring over usual care in patients with heart failure but potentially important country interactions were observed.

Aged↗

The second National Institutes of Health International Congress on advances in uterine leiomyoma research: conference summary and future recommendations.

OBJECTIVE: To summarize the proceedings of the Advances in Uterine Leiomyoma Research: 2nd NIH International Congress, which was convened on February 24-25, 2005 by the Department of Health and Human Services (DHHS), National Institutes of Health (NIH) in Bethesda, Maryland. DESIGN: Scientific information was presented at a 2-day conference, which was a collaborative effort of agencies across the DHHS and members of the academic, clinical, and medical communities involved in uterine leiomyoma research. CONCLUSION(S): The conference brought together scientists in biomedicine, epidemiology, basic research, therapeutics, and translational medicine and fostered an exchange of scientific information among members of the uterine leiomyoma research and health care communities. This document summarizes this exchange and outlines research needs and recommendations for future research directions.

Animals↗

Use of lasers in vascular disease discussed at International Congress.

In general, most of the physicians at the International Congress III, whether they were vascular surgeons, cardiologists, or radiologists, agreed that lasers have their place in vascular medicine. They did acknowledge, however, that further refinements are required in the lasers themselves and in assessment techniques for vascular interventions of any type. Such technological advancements will demand continued changes in nurses' knowledge and skills.

Angiography↗

[Congress of the Association Française d'Urologie (AFU) 2004: prostate cancer management].

Prostate cancer was the subject of communications, round tables and plenary sessions at the 98th congress of the Association française d'urologie (AFU). We report the whole of the meetings on the subject by classifying them by categories: epidemiology and biological diagnosis, information to patients included in screening (recommendations of the ANAES), biopsies and IRM, radiotherapy, radical prostatectomy, brachytherapy, HIFU (High Intensity Focused Ultrasound), functional consequences and quality of life, treatment of PSA elevation, advanced cancer of the prostate, place of surgery in T3 cancers of the prostate, research.

Biopsy↗

The American Congress of Rehabilitation Medicine: where do we go from here?

This presidential address reflects on my last 2 years as president of American Congress of Rehabilitation Medicine (ACRM). It recognizes those individuals who have been of significant help and support. The address discusses choices I have made in my professional life including selecting physical medicine and rehabilitation as a subspecialty; committing to an academic career; and choosing to get involved in local, state, national, and international physical medicine and rehabilitation societies. I review my presidential speech of 2001 when I spoke about the path we choose-to succeed or not to succeed. ACRM has come a long way in trying to succeed but continued opportunities remain in obtaining financial security, increased membership, and cost-effective and efficient management. This address includes 11 suggestions designed not only to keep the organization viable but also to allow ACRM to succeed. These suggestions include a new commitment to our strategic plan and the implementation of prioritized goals, reorganization of ACRM's national office, and adherence to a realistic budget. Finally, we must continue to move the agenda of research in rehabilitation forward much more aggressively.

Humans↗

American Congress of Rehabilitation Medicine 75th anniversary.

Despite an explosive growth of rehabilitation programs for the disabled in the years following World War II, a national professional organization that could provide a forum for exchange of scientific information on an interdisciplinary basis about multiple disability concerns did not develop. Specialization of research, education, and practice in rehabilitation has increased markedly among basic scientists, engineers, nurses, occupational therapists, orthotists and prosthetists, physical therapists, physicians, psychologists, social workers, speech pathologists, and vocational counselors. This specialization... has caused many rehabilitation-related personnel to seek a central focus of professional interaction through interdisciplinary communication. The American Congress of Rehabilitation Medicine has undergone reorganization to invite multidisciplinary membership and participation in programs advancing the arts, sciences, and practices of rehabilitation medicine. This report reviews the methodology by which the reorganization was accomplished and records the progress made in restructuring membership, program, publications, and governance. The membership body is now multidisciplinary with full participation in the scientific forum on an interdisciplinary basis by those who are active in and contributing to the advance of medical rehabilitation services for the disabled.

Physical Therapy Modalities↗

Determination of numbers of lead-exposed American children as a function of lead source: integrated summary of a report to the U.S. Congress on childhood lead poisoning.

In 1986, the U.S. Congress [Section 118(f), Superfund Amendments and Reauthorization Act (SARA)] directed the Agency for Toxic Substances and Disease Registry to provide to it a quantitative assessment of the contributions of various sources of lead to childhood exposure. We provided both a quantitative response to the mandate and a critique of low-level lead sources for U.S. population segments. We also present here an integrated assessment of major and low-level lead sources. Significant sources of lead in childhood exposure include lead in paint, dust, soil, and drinking water. Approximately 6 million U.S. children less than 7 years old reside in the oldest housing, with highest exposure risk due to leaded paint. About 2 million in deteriorated units are at particularly high risk for exposure with ca. 1.2 million children in oldest, deteriorated housing estimated to have blood lead (PbB) levels above 15 micrograms/dl. Soil and dust lead are potential sources of exposure for 6-12 million children. Residential tap water lead is a measurable source for ca. 3.8 million children, of whom the U.S. EPA estimates ca. 240,000 have water-specific exposures at toxic levels. Leaded gasoline combustion mainly in past years has produced, and will continue to produce into the 1990s, significant numbers of exposed children with toxicologically elevated PbBs. For 1990, 1.25 million children will have their PbBs fall below 15 micrograms/dl. Food lead can cause significant exposure in certain cases.

Child↗

Prenatal and postnatal effects of low-level lead exposure: integrated summary of a report to the U.S. Congress on childhood lead poisoning.

This article provides an integrated summary of a report to Congress from the Federal government (ATSDR) on childhood lead poisoning in the United States, with particular reference to low-level lead exposure and its effects on the fetus and the preschool child. As mandated by Section 118(f)(1)(C) of the 1986 Superfund Amendments and Reauthorization Act (SARA), ATSDR has examined the full spectrum of human in utero and postnatal lead toxicity, with emphasis on low-level neurotoxicity and adverse impacts on growth indices in risk populations. Especially important has been assessment of the relative persistence of these effects in later life as discernible from a number of longitudinal studies now under way around the world. Included in the Congressional report were discussions of dose-effect and dose-response relationships using blood lead levels as the indicator of lead dose.

Child, Preschool↗

Hemophilia therapy innovation: development of an advanced category recombinant factor VIII by a plasma/albumin-free method. Proceedings of a Special Symposium at the XIXth Congress of the International Society on Thrombosis and Haemostasis, July 12-18, 2003, Birmingham, UK.

Replacement therapy for hemophilia A has evolved from the early use of whole blood, citrated plasma, and cryoprecipitate, to purified factor VIII (FVIII) concentrates, first derived from plasma, then produced by recombinant DNA technology. Recombinant FVIII (rFVIII) concentrates have provided improved safety for patients with hemophilia A since they significantly reduce the risk of transmission of blood-borne infections. Nevertheless, human- or animal-derived plasma proteins are still included at some step in preparation of all previously licensed rFVIII, thereby introducing the potential for transmission of human or animal pathogens. Anti-hemophilic factor (recombinant), plasma/albumin-free method (rAHF-PFM), a novel advanced category rFVIII produced without the addition of human or animal plasma proteins, has been developed with the goal of providing the greatest possible margin of safety to hemophilia patients. This report, based on a symposium of the XIXth International Society on Thrombosis and Haemostasis Congress, provides an overview of the rAHF-PFM development program as well as current findings from the global clinical evaluation of rAHF-PFM in pediatric and adult previously treated patients.

Adult↗

Frontiers of SLE: review of the 5th International Congress of Systemic Lupus Erythematosus, Cancun, Mexico, April 20-25, 1998.

OBJECTIVE: To review the recent advances in clinical and experimental research in systemic lupus erythematosus (SLE). METHODS: Review of the 5th International Congress of SLE that took place in Cancun, Mexico, on April 20-25, 1998. RESULTS: The main topics presented at the conference are summarized. These include new findings about the genetics of SLE due to fine mapping of the patients' genes and lupus mouse models, the nucleosome as a major autoantigen in SLE, serving as an immunogen for pathogenic T helper and B cells and contributing to the development of lupus nephritis, abnormalities of apoptosis as a cause of SLE, and apoptotic mechanisms as a cause of autoimmunization. Other topics included the pathophysiologic role of anti-endothelial cell antibodies in lupus with central nervous system involvement, vasculitis, the thrombotic diathesis associated with the antiphospholipid syndrome, induction of endothelial cell apoptosis and its regulation by the idiotypic network, the penetration of antinuclear antibodies to the cytoplasm and nucleus and the subsequent interaction with cellular organelles, and new aspects in the antiphospholipid syndrome, including animal models of the disease and the importance of antibodies to beta-2-glycoprotein-I and prothrombin. Advances in the clinical aspects of SLE included clinical manifestations, diagnosis, pregnancy and neonatal SLE, infections, hormones, and treatment. Additionally, four "Lectures of A Lifetime," entitled (1) What causes lupus? (2) From natural autoimmunity to autoimmune disease; (3) The idiotypic network and SLE; and (4) Late-stage morbidity and mortality in SLE-the role of accelerated atherosclerosis were presented. CONCLUSIONS: Recent advances provide new insights into the pathogenesis of SLE, as well as hope for novel therapeutic modalities and diagnostic measures. These offer the possibility of improving life quality and decreasing mortality from the disease and its complications.

Animals↗