[Todor Margo--comparative anatomist and histologist of Serbian extraction (1816-1896)].
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Sepsis is an uncompensated bacteriemia with metastatic lesions in the form of purulent vasculites and perivascular necroses in septicemia and abscesses arising later at their sites in pyemia. Purulent resorptive fever differs from sepsis by the lack of metastatic lesions. Septic shock is caused by very acute toxicity in sepsis or purulent resorptive fever leading to disorders in microcirculation with increased permeability of vessel walls, secondary dystrophic and necrotic changes in the organs (lungs, kidneys, liver, heart).
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