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Iberian origins of New World horse breeds.

Fossil records, archaeological proofs, and historical documents report that horses persisted continuously in the Iberian Peninsula since the Pleistocene and were taken to the American continent (New World) in the 15th century. To investigate the variation within the mitochondrial DNA (mtDNA) control region of Iberian and New World horse breeds, to analyze their relationships, and to test the historical origin of New World horses, a total of 153 samples, representing 30 Iberian and New World breeds, were analyzed by sequencing mtDNA control region fragments. Fifty-four haplotypes were found and assigned to seven haplogroups. Reduced levels of variation found for the Menorquina, Sorraia, and Sulphur Mustang breeds are consistent with experienced bottlenecks or limited number of founders. For all diversity indices, Iberian breeds showed higher diversity values than South American and North American breeds. Although, the results show that the Iberian and New World breeds stem from multiple origins, we present a set of genetic data revealing a high frequency of Iberian haplotypes in New World breeds, which is consistent with historical documentation.

Americas↗

Research and development in 2000: directions and priorities for the world's poultry science community.

The challenges and targets facing the world's poultry science community in the immediate future are reviewed in the context of meeting the dietary needs for animal protein of the world population. The prior need to provide for the increasing demand for cereals, oil seeds, and grain legumes for human consumption is assessed at having a reasonable chance of success. If this need is met, the requirement for extra feed resources for increased poultry production targets is also assessed as having a reasonable chance of success. A major component of this equation is the prediction of improved efficiency of poultry production of a similar order to that of the last 50 yr arising from 1) extension of the 20th century revolution in poultry technology to over 50% of the world population compared with the present 20 to 25%; 2) recent advances in genetics, nutrition, health, housing, and husbandry still awaiting application in industry; 3) future applications from current and future research in molecular biotechnology, nutrition, health, and reproduction; and 4) the development of efficient, small-scale, extensive poultry production systems especially in countries where over 25% of the world population will still not be able to afford the products of a modern, intensive poultry industry, even in 50 yr. These challenges, targets, and predictions simply cannot be met unless the world's poultry science community increases its own efficiency, its professional initiatives to deal with the real challenges, and its social initiatives to influence socio-economic decisions on national and world stages.

Animal Husbandry↗

Disabled and elderly people in the First, Second and Third Worlds.

While disabilities occur in all societies, their causes and effects differ in the First (developed), Second (communist) and Third (developing) 'worlds'. Of the 500 million persons with disabilities, about 80% live in the Third World, and United Nations projections suggest that the proportion soon will be 90%. Two values, integration and normalization, may guide development of national policies in all three worlds. In addition, two design principles, accessibility and adaptability, may prove useful. It may also be that information-age technology will assist in disability prevention and rehabilitation, as well as in employment of individuals with disabilities. First World economics facilitate application of technology to meet special needs, Second World economies impede that, and Third World economies often cannot support it. The challenge for policy makers is to find ways of bringing together integration, normalization, accessibility and adaptability so as to help nations to fashion cost-effective solutions to their disability-related problems.

Aged↗

Pulmonary function after exposure to the World Trade Center collapse in the New York City Fire Department.

RATIONALE: On September 11, 2001, the World Trade Center collapse created an enormous urban disaster site with high levels of airborne pollutants. First responders, rescue and recovery workers, and residents have since reported respiratory symptoms and developed pulmonary function abnormalities. OBJECTIVES: To quantify respiratory health effects of World Trade Center exposure in the New York City Fire Department. MEASUREMENTS: Longitudinal study of pulmonary function in 12,079 New York City Fire Department rescue workers employed on or before 09/11/2001. Between 01/01/1997 and 09/11/2002, 31,994 spirometries were obtained and the FEV(1) and FVC were analyzed for differences according to estimated World Trade Center exposure intensity. Adjusted average FEV(1) during the first year after 09/11/2001 was compared with the 5 yr before 09/11/2001. Median time between 09/11/2001 and a worker's first spirometry afterwards was 3 mo; 90% were assessed within 5 mo. MAIN RESULTS: World Trade Center-exposed workers experienced a substantial reduction in adjusted average FEV(1) during the year after 09/11/2001 (372 ml; 95% confidence interval, 364-381 ml; p < 0.001) This exposure-related FEV(1) decrement equaled 12 yr of aging-related FEV(1) decline. Moreover, exposure intensity assessed by initial arrival time at the World Trade Center site correlated linearly with FEV(1) reduction in an exposure intensity-response gradient (p = 0.048). Respiratory symptoms also predicted a further FEV(1) decrease (p < 0.001). Similar findings were observed for adjusted average FVC. CONCLUSIONS: World Trade Center exposure produced a substantial reduction in pulmonary function in New York City Fire Department rescue workers during the first year after 09/11/2001.

Adult↗

World reconstruction in psychotherapy.

The purpose of this article is to articulate how we, as psychotherapists, can transform the worlds of our clients. In part one of the article, the concept of "world," the dynamics of how worlds operate, and the clinically relevant notions of "problematic worlds" and "impossible worlds" are explicated. In part two, therapeutic recommendations for helping clients to reconstruct their worlds are presented, with special emphasis on problems of grief post-traumatic stress disorder, and the experience of meaninglessness.

Adaptation, Psychological↗

Serum leptin in nonpregnant and pregnant women and in old and new world nonhuman primates.

Leptin is a hormone that is produced during mammalian pregnancy in the placental trophoblast and other tissues, including! fetal and maternal adipocytes. Synthesis of the polypeptide and the presence of its specific receptors throughout the human maternal fetoplacental unit suggest direct effects on conceptus growth and development. However, both the physiologic roles of leptin and the mechanisms regulating leptin synthesis in human pregnancy differ from those in laboratory and domestic species, necessitating the development of non-human primate research models. Therefore, we compared serum leptin concentrations in nonpregnant and pregnant women with those in both old world nonhuman primates (i.e., baboon, rhesus monkey, cynomolgus monkey) and new world nonhuman primates (i.e., squirrel monkey, titi monkey). As expected, maternal leptin levels were elevated in human and baboon pregnancies (P < 0.05 and P < 0.001, respectively). Levels in both species of old world monkeys were also greatly enhanced (P < 0.001). Although maternal serum concentrations were slightly elevated compared to nonpregnant levels in both species of new world monkeys, overall concentrations were dramatically lower than for either old world primates or humans. Results provide comparisons of serum leptin concentrations in pregnant and nonpregnant humans and baboons with those in both old and new world monkeys and further characterize these nonhuman primates as models for the investigation of leptin dynamics in pregnancy.

Animals↗

Phylogeny of Old and New World vultures (Aves: Accipitridae and Cathartidae) inferred from nucleotide sequences of the mitochondrial cytochrome b gene.

The molecular phylogeny of 11 Old World and 5 New World vultures was inferred from nucleotide sequences of the mitochondrial cytochrome b (cyt b) gene. According to this analysis carrion-feeding has evolved independently at least three times during evolution: 1.) In the New World vultures, which are clearly separated from vultures of the family Accipitridae; 2.) in the Neophron-Gypaetus clade which is positioned at the base of the Accipitrid tree and 3.) in the Gyps-Aegypius-complex which encloses the largest group of Old World vultures. Thus the genetic data clearly show that the carrion-feeding lifestyles and associated morphologies shared by New and Old World vultures are rather based on convergence than on close genetic relatedness. Employing the cyt b sequences of 12 other members of the Falconiformes and 10 members of the Ciconiiformes (sensu Sibley and Monroe, 1990) the phylogenetic relationship between the three clades of vultures and these other taxa was assessed. New World Vultures appear to share distant ancestry with storks but a close relationship is unlikely.

Animals↗

The changing role of the World Bank in global health.

The World Bank began operations on June 25, 1946. Although it was established to finance European reconstruction after World War II, the bank today is a considerable force in the health, nutrition, and population (HNP) sector in developing countries. Indeed, it has evolved from having virtually no presence in global health to being the world's largest financial contributor to health-related projects, now committing more than $1 billion annually for new HNP projects. It is also one of the world's largest supporters in the fight against HIV/AIDS, with commitments of more than $1.6 billion over the past several years. I have mapped this transformation in the World Bank's role in global health, illustrating shifts in the bank's mission and financial orientation, as well as the broader changes in development theory and practice. Through a deepened understanding of the complexities of development, the World Bank now regards investments in HNP programs as fundamental to its role in the global economy.

Global Health↗

The capitalist world-system and international health.

A number of world health problems which have been discretely considered in the past are viewed in this paper as interwoven with each other and with the functioning of the capitalist political-economic world-system. Thus, climactic explanations ("tropical medicine"), and even poverty when conceived in cultural terms or as a structural problem resident entirely within a single nation, are seen as inadequate for understanding any or all of the problems discussed briefly here: poor general health levels in peripheral and semi-peripheral nations, especially rising infant mortality rates in countries such as Brazil; comerciogenic malnutrition; dumping and exploitative sale of drugs, pesticides and other products banned or restricted in core nations; genocidal and other threatening approaches to population control; export of hazardous and polluting industry to peripheral and semi-peripheral nations; similar export of human experimentation; the sale of irrelevant, high medical technology to countries lacking basic public health measures, the "brain drain", and medical imperialism. Also discounted are moralistic inveighing, complaints about inadequate information and its transfer, discussions of bureaucratic bumbling or inter-agency politics and professional rivalries, various forms of victim-blaming, and other explanations and corrective approaches which ignore class structure and the control, distribution, and expropriation of resources in nations and the world-system. The framework suggests the importance of a worldwide cultural hegemony, including a medical cultural hegemony, established by and in the service of the ruling classes. Socialist-oriented nations which are quasi-independent of the capitalist world-system are seen as suffering less from its effects. This suggests that we should conceive of world socialist health and world capitalist health, rather than any kind of unified phenomenon called "international health".

Drug Industry↗

Global work force 2000: the new world labor market.

Just as there are global markets for products, technology, and capital, managers must now think of one for labor. Over the next 15 years, human capital, once the most stationary factor in production, will cross national borders with greater and greater ease. Driving the globalization of labor is a growing imbalance between the world's labor supply and demand. While the developed world accounts for most of the world's gross domestic product, its share of the world work force is shrinking. Meanwhile, in the developing countries, the work force is quickly expanding as many young people approach working age and as women join the paid work force in great numbers. The quality of that work force is also rising as developing countries like Brazil and China generate growing proportions of the world's college graduates. Developing nations that combine their young, educated workers with investor-friendly policies could leapfrog into new industries. South Korea, Taiwan, Poland, and Hungary are particularly well positioned for such growth. And industrialized countries that keep barriers to immigration low will be able to tap world labor resources to sustain their economic growth. The United States and some European nations have the best chance of encouraging immigration, while Japan will have trouble overcoming its cultural and language barriers.

Adult↗

Gender differences in navigating virtual worlds.

Navigation and wayfinding are key human factors in information processing and performance in the virtual worlds. Earlier studies have focussed on finding effective navigational aids that would support skilled wayfinding behavior of humans in large virtual worlds. Also, on a separate but related field there have been speculations that there exist biological differences between men and women's directional sense that leads to difference in performances on everyday spatial tasks in the real world. This paper focuses on findings of an experiment that was designed to elucidate the gender differences in navigating a dense, large virtual world namely the virtual Iowa State University (ISU) campus simulated in the projection based C2 virtual reality system. Equal number of subjects from both the genders with varied background (age, computer skills etc.) were assigned tasks that required them to navigate their way from one location to another within the school campus. Performance in the virtual world was studied in terms of time taken, distance traveled, number of wrong turns, number of times the subject got lost and navigation strategies/techniques used by the subjects. We conclude that there are reliable gender based differences in navigating large virtual worlds.

Adult↗

Declining world fertility: trends, causes, implications.

This Bulletin examines the evidence that the world's fertility has declined in recent years, the factors that appear to have accounted for the decline, and the implications for fertility and population growth rates to the end of the century. On the basis of a compilation of estimates available for all nations of the world, the authors derive estimates which indicate that the world's total fertility rate dropped from 4.6 to 4.1 births per woman between 1968 and 1975, thanks largely to an earlier and more rapid and universal decline in the fertility of less developed countries (LDCs) than had been anticipated. Statistical analysis of available data suggests that the socioeconomic progress made by LDCs in this period was not great enough to account for more than a proportion of the fertility decline and that organized family planning programs were a major contributing factor. The authors' projections, which are compared to similar projections from the World Bank, the United Nations, and the U.S. Bureau of the Census, indicate that, by the year 2000, less than 1/5 of the world's population will be in the "red danger" circle of explosive population growth (2.1% or more annually); most LDCs will be in a phase of fertility decline; and many of them -- along with most now developed countries -- will be at or near replacement level of fertility. The authors warn that "our optimistic prediction is premised upon a big IF -- if (organized) family planning (in LDCs) continues. It remains imperative that all of the developed nations of the world continue their contribution to this program undiminished."

Africa↗

[A world tailored for children and the young. The children and the young around us and the child and the adolescent within each of us].

UNLABELLED: Towards the end of the nineteenth century in America, a court that normally dealt with animal abuse found itself facing a very special problem: it had to discuss for the very first time a case of child abuse. It might seem a paradox to many that a matter of this nature should be discussed in a court set up for a quite different purpose, but it was not an error arising out of the lack of room in the civil court nor an error of competency: it happened to be the only place judged to be appropriate to discuss the rights of a child, mistreatment of whom was handled on a par with abuse of animals. In spite of the section expressly dedicated to children in the Universal Declaration of Human Rights of 1789, the world had to wait for the Geneva Convention of 1924 before the first declaration of children's rights was promulgated. There were five main principles: the right to a healthy psychophysical development, the right to be nourished, cared for, returned to a normal life if demoralised, looked after and aided in the case of orphans. But only with the international Convention of children's rights of New York in 1989 was it possible to draft a text for the full, more comprehensive protection of infancy, two centuries after the first pronouncement on the occasion of the universal declaration of human rights. Two centuries of struggles and growing awareness of the problem of children (and at the same time of women and mothers) in the world, two centuries that have produced all over the world the complete idea of the child as having rights and being an active part of contemporary society. But the examination of the current situation brings us to the main problem: if a virtuous circle is not established between rights, infant culture and duties of adults, then the declarations of this century will have to wait many years more before becoming a practical part of our society. What then should be done to make sure that the declarations and conventions on rights do not remain a mere expression of principles? There can be no evolution in children's living conditions, nor protection of their rights, if we do not create a culture of infancy based on two premises: the rights of children and the duties of adults with respect to children. Today an exact and comprehensive knowledge of the rights of children is necessary above all starting with their right to freedom, experience, opinion, equal opportunity for development and education, defence against all types of abuse, and their right to a family. But at the same time it is necessary to act in the area of the duties of parents and adults: the question is one of building up a cultural system that includes the rights whereby the prerogatives of children are matched with corresponding duties of adults, a culture of values that responsibilises adults by way of a process of personal awareness and parent training. The adult must find himself personally in harmony in his relationship with life so as not to compromise on child training: the idea of a vulnerable future must be avoided; a future that is insecure and defenceless for children and adolescents who are future adults. A third factor must cater for this, namely modern society whose task it is to build structures (interconnected by means of an interdisciplinary project and through the possibility that modern technology also offers them) to supply opportunities and laws that favour and protect the personality of both child and adult. In this case considerable value would be taken on by the drafting of a "Charter of Duties of adults with respect to children and adolescents" that favours the birth of new standards and national and international conventions aimed at a new conception of society understood as a set of several parts, children, adolescents, adults, each subject of rights. By this approach the commitment of individual associations, organisations and institutions would start a process of social development which as of today is the last and on]y real revolution possible to improve the conditions of life of the person as such, and not the person as such, and not only of the person as a citizen of one nation or another. IN CONCLUSION: no development is possible if we do not take steps as an international community to protect the first citizens of the world who are and always will bc children. 1n this sense, psychoanimation, which is a psychopedagogic-cultural intervention methodology based on a holistic approach and employs cognitive, creative, corporeal techniques to foster, in the individual and in the group, that ''growth'', that "awareness'', that "responsibility'' which have their "roots'' in self-awareness and in the possibility of acquiring cultural instruments that are scientifically and humanistically suitable to ''act'' individually and collectively, the "change'' in human societies sets itself the diffusion of a Culture of Infancy and of Adolescence as an objective. In fact for Psychoanimation that means: (''give soul to the soul'' employing all languages in interdisciplinary fashion for communication and social integration) in order to authentically permit knowledge, communication and exchange among human beings) the last ''possible revolution" is that connected with the success, all over the world, of a Culture of Infancy and of Adolescence. What is the possibility that this converts into: ''a world made to the measure of children'': the children around us and the chi]d within us!

Adolescent↗

The new world disorder.

On January 1, 1995, representatives from 76 countries signed the World Trade Organization charter, which for years had been part of a temporary trade agreement. The WTO's emergence as a fully empowered supranational body seemed to reflect the triumph of what the first President Bush had described as the "new world order." That order was based on two assumptions: that a healthy economy and a sound financial system make for political stability, and that countries in business together do not fight each other. The number one priority of U.S. foreign policy was thus to encourage the former Communist countries of Europe and the developing nations in Latin America, Asia, and Africa to adopt business-friendly policies. Private capital would flow from the developed world into these countries, creating economic growth. It sounded too good to be true, and so it proved. The new world order of Bush père and his successor, Bill Clinton, has been replaced by the new world disorder of Bush fils. Under the second Bush's administration, the economic and political rationale-behind the Washington consensus of the 1990s has unraveled, forcing a radical change in our perceptions of which countries are safe for business. Negotiating this new environment will require companies to more rigorously evaluate political events and more carefully assess the links between political, economic, and financial risk factors. They'll need to be more selective about which markets to enter, and they'll need to think differently about how to position themselves in those markets. The geopolitical events of the past year, the Bush administration's global war on terror, as well as ongoing convulsions in traditional political and economic relationships must be understood and managed by corporate leaders worldwide. With careful analysis, business leaders can increase their companies' visibility and better respond to the uncertainties of the new world disorder.

Capitalism↗

Changing the medical world order with technological advances: the future has only begun.

It is a great honor to contribute in a small way to this book which in a way celebrates the continued evolution of telemedicine in Kosova. I was privileged to visit this brave land on several occasions in the last years. Severe circumstances were repeatedly resolved through great personal and professional sacrifice. Revolutionary solutions have been applied where evolutionary development was simply too slow in the realization of a new land in a complex world. In some ways telemedicine is emblematic of such struggle and success. We aspire to world health when world peace is elusive and hunger haunts us in the midst of plenty. Telecommunications have made it easy to report the failings of medicine, the injustice of health care and the unmet promise of political endeavor. It is the promise of telemedicine to use those same channels of information to empower, unify and advance the cause of health rather than only report the failings. Telemedicine entails the use of telecommunications and information technology to support the delivery of health care at a distance. There are critics who believe telemedicine is a waste of precious resources, which are needed urgently for higher health priorities. Telemedicine is dismissed as an expensive irrelevance, another distraction from the real needs of medicine in a chaotic world. That is patently ridiculous. Telemedicine is a part of the wider phenomenon of information and information is arguably the strongest change agent in play for medicine and other societal elements as well. A well-informed public armed with the tools for self-determination and the evidence for efficient action cannot be corrupted. Telemedicine is a part of the great change information brings to the world order, a drastic change toward a better world of health and justice.

Delivery of Health Care↗

World population. Past, present and future trends.

The history of, and prospect for, world population growth is presented in this study. The study is based mainly on data compiled and published in the last years by the population Division, the Food and Agriculture Organisation, the International Labour Organisation of the United Nations and the World Bank. The population of the world grew from about 300 million at the beginning of the Christian era to half billion in 1650 to one billion in 1800, to two billion in 1927, to three billion in 1960, to four billion in 1974, and to five billion in 1987. According to the medium variant of the United Nations projections the population of the world will reach six billion in 1988, seven billion in 2010, eight in 2023, nine in 2050, and ten around 2100. This number demonstrate the acceleration growth rate of world population which is explained be the theory of demographic transition. In 1985 developing countries had 3663 million persons or about three-fourths of the total population of the world. According to medium variant of projection the less-developed areas would increase their population to 4845 person by the end of the century or by four-fifths of the total. In contrast the developed countries would increase from 1174 million persons in 1985 to only 1277 million in 2000. Examining estimates of total and per capita income we must be impressed with the wide difference between the wealthiest and the poorest countries. The developed countries having the highest average incomes have undergone industrialization and modernization of the economy; the developing countries with lowest incomes are those with a predominance of agriculture in most cases. Statistical data shows that the disparity between the prosperity of the industrial countries and the poverty of the preindustrial countries was increasing in the last two decades.

Age Factors↗

Molecular evidence for the importation of Old World Leishmania into the Americas.

A brief review of work carried out by the laboratory on the systematics of trypanosomatids during the last three years is given. The principal line of research has been on the taxonomy of New World Leishmania and one of the topics studied has been the determination of the autochthonous origin of certain Leishmania species found in the New World. Controversy exists as to whether the etiological agent of American Visceral Leishmaniasis is indigenous. Here, we present evidence from enzyme electrophoresis and schizodeme analysis indicating that L. chagasi has a recent origin and that it is similar to L. infantum. We also describe L. major-like isolates which have been found in the New World and present evidence suggesting that some of these populations may have been imported into the Americas. Reference strains from the subgenus Viannia are examined and compared with other Old World and New World species by enzyme electrophoresis. The results are analyzed numerically and we show that the Viannia species are a group of parasites indigenous to the New World that cluster separately from other Leishmania species. The numerical analyses also indicate that the subgenus forms a monophyletic group in contrast to the subgenus Leishmania which appears to be polyphyletic.

Americas↗

Parallel pathways in the retina of Old and New World primates.

Old-world simians are all trichromats, but in most new-world primates there is a polymorphism; males are dichromats but most females are trichromats. In the old world simian, luminance and red-green chromatic channels defined by psychophysical experiments have as a basis parasol ganglion cells of the magnocellular (MC) pathway and midget ganglion cells of the parvocellular (PC) pathway respectively. Small bistratified ganglion cells provide a basis for a blue-yellow chromatic channel, which should probably be considered a separate entity. In both dichromatic and trichromatic new-world animals, the MC pathway and the small bistratified, blue-yellow system seem anatomically and physiologically similar to those in their old-world relatives. The midget ganglion cells of the parvocellular pathway in trichromats are anatomically and physiologically similar to the old-world pattern. In dichromatic animals, they are anatomically similar and physiologically resemble those of trichromatic animals, except for the lack of chromatic opponency. We conclude that these three systems may from a basic pattern for the visual pathway of primates. However, the results from dichromats indicate that the evolution of trichromacy may be found to be more complex than presently supposed.

Animals↗