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[Metacarpophalangeal calcifications in diffuse chondrocalcinosis. Radiologic study of ten cases (author's transl)].

The authors report ten cases of metacarpophalangeal calcifications in chondrocalcinosis. These calcifications are associated with a calcification of the triangular ligament of the wrist in the all cases. Cartilaginous calcifications of the wrist are found in 9 cases. Metacarpophalangeal calcifications concern mostly the third (9 cases) and the second (6 cases) metacarpophalangeal joint. They are present frequently on radial side (29 joints) rarely on cubital side (5 joints) with a calcification on radial and cubital side in 4 joints and a calcification on cubital side only in one joint. Calcic deposit concern almost the synovial and capsule, it is rarely cartilaginous one. The authors discuss the possibility of calcic deposit of the glenoidal fibrocartilage of the metacarpophalangeal joint.

Aged↗

Changes in the content of the fibrillar collagens and the expression of their mRNAs in the menisci of the rabbit knee joint during development and ageing.

The menisci are first seen as triangular aggregations of cells in the 20-day rabbit fetus. At 25-days, a matrix that contains types I, III and V collagens has formed. These collagens are also found in the 1-week neonatal meniscus, but by 3 weeks, type II collagen is present in some regions. By 12 to 14 weeks, typically cartilaginous areas with large cells in lacunae are found and by 2 years, these occupy the central regions of the inner two-thirds of the meniscus. The surface layers of the meniscus contain predominantly type I collagen. From 12 to 14 weeks onwards, there is little overlap between the regions with types I or II collagens, that is, these are discrete regions of type I-containing fibrocartilage and type II-containing cartilage. Types III and V collagens are found throughout the menisci, particularly in the pericellular regions. All the cells in the fetal and early neonatal menisci express the mRNA for type I collagen. At 3 weeks postnatal, cells that express type I collagen mRNA are found throughout the meniscus, but type II collagen mRNA is expressed only in the regions of developing cartilage. At 12- to 14-weeks, only type II collagen mRNA is expressed, except at the periphery next to the ligament where a few cells still express type I collagen mRNA. Rabbit menisci, therefore, undergo profound changes in their content and arrangement of collagens during postnatal development.

Aging↗