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[Pseudomembranous rectocolitis].

The following conclusions were drawn from a study of 15 cases of pseudo-membranous coloproctitis (PMCP): PMCP was seen in subjects of both sexes and all ages. The causative agent was found in all antibiotic classes. Clinical signs comprised constant diarrhea, fever, abdominal pain, toxic shock and, more rarely, pseudo-occlusive, pseudo-perforative surgical evidence. Diagnosis involved visualization of pseudo-membranes by endoscopy. Lesions were most frequent in the left colon and increased in severity towards the distal end. Three stages were distinguished by histological examination: superficial necrosis of the mucous membranes, interruption of glands, complete necrosis of the mucous membrane. Without preparation the abdomen did not provide specific information; nor did barium enema which revealed lesions that were frequently diffuse but more marked in the left colon. Conventional coprocultures did not provide diagnostic information. Only a more sophisticated technique will be capable of detecting the pathogen currently considered to be the cause of PMCP: Clostridium difficile. The course of the disorder is generally satisfactory under medical treatment (parenteral feeding, vancomycin) but may sometimes call for surgery.

Cholestyramine Resin↗
PubMed1985

[Rectocolic endometriosis].

The authors distinguish two major varieties of rectocolonic endometriosis: the isolated benign sigmoid endometrioma which is difficult to distinguish from malignant lesions of the mucosa; the tendency to progressive stenosis is an indication for surgical excision of this lesion. Genital endometriosis which has spread to the intestinal tract. The genital and peritoneal lesions facilitate the diagnosis of the recto-sigmoid lesion. On the other hand, the intestinal involvement complicates the therapeutic. Low rectal involvement usually consists of endometriosis grafted to a perineal scar.

Endometriosis↗