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Perceptions of sedentary African-American women about continuous versus intermittent walking.

To meet current physical activity recommendations, a person may chose to adopt a continuous or an intermittent physical activity program, as long as they accumulate 30 minutes of moderate-intensity physical activity most days of the week. Sixty-four sedentary African-American women were surveyed to assess whether perceptions about continuous and intermittent walking programs differed. Specifically, we assessed whether perceptions of self-efficacy, outcome expectations, social support, and the environment varied with respect to walking programs. Results indicated that the women perceived higher self-efficacy for the intermittent walking program and associated this program with more favorable environmental factors (p < .05). However, they expected greater benefits from the continuous walking program (p < .05). Overall, 65% of the women reported that they would prefer to adopt the continuous walking program.

Adult↗

Caspase-independent programmed cell death with necrotic morphology.

Cell death is generally classified into two large categories: apoptosis represents active, programmed cell death, while necrosis represents passive cell death without underlying regulatory mechanisms. Recent progress revealed that caspases, a family of cysteine proteases, play a central role in the regulation of apoptosis. Unexpectedly, however, caspase inhibition occasionally turns the morphology of programmed cell death from apoptotic into necrotic without inhibiting death itself. In this article, we review different models of caspase-independent programmed cell death showing necrotic-like morphology, including our Ras-mediated caspase-independent cell death. Based on these findings, we suggest the existence of a necrotic-like cell death regulated by cellular intrinsic death programs distinct from that of apoptosis. Even though type 2 physiological cell death, or autophagic degeneration, has been recognized as a necrotic-like programmed cell death for a long time, the underlying molecular mechanisms have not been identified despite its physiological significance. This has been in part due to the previous absence of adequate caspase-independent cellular models to study, recent efforts may now help to elucidate these mechanisms.

Animals↗

An organization-environment framework for assessing program implementation.

Evaluations of health programs are typically conducted from a rational bureaucratic framework in which client change and client outcome are seen as logical outcomes of program activity. This paper proposes a theoretical framework for examining organizational consequences of program implementation. Factors in the internal environment (e.g., the hospital) and the external environment (e.g., the community) which contribute to the program's success or failure, are considered. Observational and structured interview data are used to compare two state funded perinatal projects, one an organizational "success" and the other a costly failure. Attributes of external environments which may be important to successful implementation include demand for services, provider competition, access to information, social beliefs, and professional commitment. Important features of the internal environment include host organization commitment and conflict, and structural attributes: complexity, formalization, centralization, and coordination. The paper concludes with theoretically-based questions which serve as guidelines for process evaluation.

California↗

Practice patterns for long-term follow-up of adult-to-adult right lobectomy donors at US transplantation centers.

Protocols used by transplant centers to care for donors after right hepatectomy for living donor liver transplantation are not well described in the medical literature. Our goal is to describe practice patterns for the long-term follow-up of adult-to-adult right lobectomy donors at US transplantation centers. All adult liver transplantation centers listed with the United Network for Organ Sharing were surveyed between October and November 2002. A transplant coordinator, hepatologist, or surgeon from each center completed a 10-item telephone questionnaire. Of 97 adult liver transplantation centers, 90 centers (92.8%) completed the survey. Ninety-six percent of participants were transplant coordinators; 2%, hepatologists; and 2%, surgeons. One thousand forty-four right lobectomies have been performed by 51 (56.7%) transplant programs (range, 1 to 101 per center). Thirty-eight percent of active programs have performed fewer than 10 donation right lobectomies. Fifty-one percent of programs have a transplant coordinator who works specifically with donors. Thirty-five programs (68.3%) have a formal follow-up protocol, and an additional 13 centers (14.4%) reported their usual follow-up patterns. Protocols ranged from no formal follow-up to visits every few weeks in the early postoperative period followed by evaluation every 6 months. Evaluation beyond 12 months is typically on an as-needed basis. Personal psychosocial support services after donation were unusual and included regular phone calls from the coordinator (5 centers), quality-of-life instruments (3 centers), scheduled follow-up with the psychologist (1 center), or a satisfaction survey (1 center). Several centers provided newsletters, combined donor-recipient support groups, recognitions parties, and certificates. There is significant variability in the long-term care of donors. Formal psychosocial support after donation is rare.

Adult↗

Helping oneself by helping others: evaluation of a service credit banking demonstration.

Between 1987 and 1990, the Robert Wood Johnson Foundation funded six service credit banking demonstration programs among the elderly in which participants delivered services in return for credits, entitling them to later service. This evaluation of the demonstrations found that these six sites successfully attracted elders for the delivery of household support services to a relatively old, frail population with potentially limited social networks. Evidence on the significance of the "credit" in attracting volunteers was mixed, but the programs have attracted new volunteers, and have not substituted for other volunteer activities. Program development has entailed considerable staff investment in volunteer support; programs are better understood as community membership organizations than as mechanical exchanges.

Aged↗

Evaluation of a culturally appropriate intervention to increase physical activity.

OBJECTIVE: To evaluate a culturally appropriate intervention to increase activity in overweight Mexican American women. METHODS: Participants were randomly assigned to a physical activity program or wait-list control. RESULTS: Treated participants were not more active than controls at 6 or 12 months. In addition, we found no significant differences in the proportion of individuals who met an objective criterion for physical activity from baseline to 6 months in the treatment or control groups. CONCLUSION: The intervention did not increase physical activity in this population. Differences in baseline activity and contamination of the control group may partially account for the outcome.

Adolescent↗

Teaching laparoscopic sterilization.

First-year obstetrics-and-gynecology residents participated in the attempted sterilization of 411 women by either Falope Ring application (FRA) or bipolar electrocoagulation (LTC). Ability to complete the procedure, as well as intraoperative and immediate postoperative complication rates, was reviewed. Characteristics that predisposed women to complications were assessed. Complications were more common in 165 women who underwent sterilization with FRA than in those who had LTC. Two FRA patients (0.9%) required laparotomy because of bleeding. In addition, failure to establish a pneumoperitoneum led to a minilaparotomy in one case. Nineteen FRA women (11.5%) experienced minor complications. The only major complications with the use of LTC were the need for minilaparotomy in two women in whom a pneumoperitoneum could not be established. Minor complications occurred in 4 of 227 LTC cases (1.8%). Current or past patient characteristics did not influence outcome except in the cases of failure to establish a pneumoperitoneum; those women were significantly heavier than others in this series. Limited experience in the instruction of FRA may have contributed to the higher complication rate and to the greater number of problems complicating sterilization with FRA as compared to LTC.

Electrocoagulation↗

Use of ethnography in the evaluation and targeting of HIV/AIDS education among Latino farm workers.

Ethnography can be utilized to assess the impact of HIV/AIDS education simultaneous with the implementation of program activities. An ethnographic analysis based on field methods adapted in a Michigan program that targets migrant farmworkers highlights responses to showings of a bilingual AIDS education video; the things to which migrants attend while they are interacting with the educator and each other in HIV education presentations; the tactics they employ to direct discussion when talking about HIV/AIDS, and the manner in which they use language to "distance" themselves from the topic of HIV infection and AIDS. Migrants in Michigan experience the same risks to health as farmworkers in other states; their pay is low, their hours are long, and the time they spend in the state is seasonal (summer). They engage in risk behavior while in the state (primarily consensual/contracted sex). Some migrants through use of drugs may come closer to exposure to the HIV virus outside the state than when they are working as migrants in Michigan.

Acquired Immunodeficiency Syndrome↗

Biological warfare in a historical perspective.

There are some early examples of biological warfare (BW), but in modern times it was used first for sabotage by Germany during WWI. Development of biological weapons on a military significant scale was initiated in several countries in the period between the world wars. During WWII, several countries had active programs such as the USA, UK, Canada, Germany, Japan and the Soviet Union. It was only Japan that on a fairly large scale used BW. The US program continued until 1969, when President Nixon took a decision to end it in connection with signing the BTWC. The Soviet Union had also continued its program after the war, and this was enhanced after signing the BTWC: in the 1980s the program consisted of around fifty facilities and involved around 60,000 people. The Soviet Union produced and maintained a large stockpile of BW-agents. After the collapse of the Soviet Union, and due to pressure from USA and UK, President Yeltsin issued a decree in 1992 banning continued offensive BW activity. However, there are still concerns of residual activity in Russia. Another program of concern is the Iraqi BW-program. After 10 years of UN inspections that were stopped in 1998, there are still many unanswered questions concerning the BW program. There was also a covert BW-program in South Africa that was terminated around 1993. There have also been a number of allegations of alleged use or possession. In addition, there are indications that 10-12 states are now trying to acquire BW, and this assessment is based on intelligence information, mainly from the USA. For example Iraq, North Korea, Iran, Syria, Sudan and Libya. Another aspect is the strong driving force of technology developments to promote this type of program, opening new risks for future potential military misuse.

Animals↗