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PubMed1992

Clinical implications of vergence adaptation.

Placement of a prism in front of an eye results in a change in the tonic position of the eyes, a shift in the forced fixation disparity curve, and a shift in fusional amplitudes. These changes remain in effect as long as motor fusion is maintained. Elimination of fusion by occlusion or by removal of the prism results in a slow movement of the eyes back to the preprism position. This phenomenon, known as prism adaptation or slow fusional vergence, has important clinical implications in maintaining binocular vision with anisometropic prescriptions, age-related physiological changes in the positions of the eyes, blinking, high phorias, etc. Vergence adaptation is useful in explaining previous discrepancies between alternate and unilateral cover test, pre- and postorthoptic ACA ratios, stimulus and response ACA ratios, changes in phorias after orthoptics, and the observation of patients "eating up prism." Vergence adaptation anomalies have been implicated in causing asthenopia. Adaptation has been shown to change after orthoptic therapy. This paper reviews the clinical findings associated with vergence adaptation.

Adaptation, Ocular↗
PubMed1992

Treatment options in intermittent exotropia: a critical appraisal.

Clinical opinions regarding treatment of intermittent exotropia (IXT) vary widely and there is controversy as to which treatment modality is most successful. This paper reviews the clinical literature related to five different treatment modalities used for IXT: overminus lens therapy, prism therapy, occlusion therapy, extraocular muscle surgery, and orthoptic vision therapy. Based upon review of 59 studies of treatment of IXT, and using each author's stated criteria for success, the following pooled success rates were revealed: over-minus lens therapy (N = 215), 28%; prism therapy (N = 201), 28%; occlusion therapy (N = 170), 37%; extraocular muscle surgery (N = 2530), 46%; and orthoptic vision therapy (N = 740), 59%. Success rates for IXT surgery differed depending upon whether a functional (43%) or cosmetic (61%) criterion was used to evaluate treatment success. These pooled success rates must be viewed carefully because nearly all the studies suffer from serious scientific flaws such as small sample sizes, selection bias, inadequately defined treatments and success criteria, absence of statistical analysis, and results reported in a manner that makes interpretation difficult. These problems indicate the need for a careful, circumscribed, and well controlled clinical trial to study the efficacy of different treatment modalities in remediating IXT.

Contact Lenses↗
PubMed1974

Eye defects of mentally handicapped children.

Among 171 children who received routine ophthalmic and orthoptic examinations as part of their evaluation for suspected or known developmental handicap it was found that there was an unusually high incidence of ocular defects. Especially prevalent were high refractive errors (52%) and squints (40%), but there were also a number of other serious eye defects ranging from nystagmus and cataracts to microphthalmos.Because of this high incidence of eye defects it was considered essential that ophthalmic and orthoptic examinations should be part of the routine evaluation of developmentally handicapped children by the team of workers in an assessment centre.

Cataract↗
PubMed2000

The effectiveness of preschool vision screening by health visitors.

The aim of this study was to determine the effectiveness of preschool vision surveillance by health visitors in Warrington, a district with a secondary community orthoptic service. Of the 2041 children screened by health visitors at 3-3 1/2 years 12% were referred to the orthoptist for further assessment. Sixty-three per cent of these required more than one examination by the orthoptist and 28% were subsequently referred to an ophthalmologist for further assessment. Amblyopia was detected in 11 children, 5 had squints without amblyopia, and in addition 25 children had significant refractive errors. A retrospective review of the records of children identified with amblyopia following a school entry medical at 5 years was undertaken to detect possible failure of the earlier health visitor examination (i.e. false negatives at age 3-3 1/2 years). Possible failure of early screening was found in only two children, one of whom had a minor defect only (6/9). Vision screening for children aged 3-3 1/2 years by health visitors is an effective alternative to primary screening by orthoptists. However, the use of health visitors in this role is contrary to current national guidelines. The findings suggest that using health visitors to screen vision in preschool children makes efficient use of existing routine checks and may be the best use of orthoptic time.

Child, Preschool↗
PubMed1996

Methodology for a randomised controlled trial of preschool vision screening. A new approach with the 'ALSPAC' project.

We present the methodology of a population-based Randomised Controlled Trial, comparing an intensive programme of primary preschool vision screening by orthoptists with the usual non-specialist screening. The aims of the trial are to compare the effectiveness and costs of intensive orthoptic screening with non-specialist measures. The orthoptic screening programme will be evaluated both as a composite package and in terms of the screening value of the individual tests at specific ages. This trial is nested within a large population-based longitudinal study. Additional demographic and developmental data on the children in the trial are therefore available. The results of the trial will be used to help clarify which methods of preschool ophthalmic population screening are best in terms of disease detection and cost efficiency.

Amblyopia↗
PubMedDate not supplied

Effectiveness of laser in situ keratomileusis with the Nidek EC-5000 excimer laser for pediatric correction of spherical anisometropia.

PURPOSE: To determine the effectiveness of laser in situ keratomileusis (LASIK) for correction of spherical anisometropia in patients under 18 years of age. METHODS: Thirty-eight patients (58 eyes) with myopic spherical anisometropia and spherical antimetropia were treated. Group 1 included 31 eyes of 20 children (9 to 15 yr) and Group 2 included 27 eyes of 18 children under 18 years old (16 to 17 yr). The difference in refraction between the two eyes in Group 1 was an average 5.95 D and in Group 2, 6.92 D. The operations were performed with the Nidek EC-5000 eximer laser and the Hansatome Chiron Vision HT-230 microkeratome. The procedure was performed under local anesthesia. Patients were followed for 18 months. Occlusion therapy was started 2 weeks postoperatively and continued for 3 to 4 months. Ten patients suffered from strabismus; they received orthoptic therapy. RESULTS: Uncorrected visual acuity (UCVA) and best spectacle-corrected visual acuity (BSCVA) improved after LASIK. The difference in refraction between the two eyes was reduced as was the angle of strabismus. Binocular vision improved in one patient and simultaneous vision improved in three patients (vision in these patients was monocular before treatment). CONCLUSIONS: LASIK with the Nidek EC-5000 excimer laser and the Hansatome Chiron Vision HT-230 microkeratome, together with occlusion and orthoptic therapy for pediatric correction of spherical anisometropia, may be an effective procedure that facilitates increased visual acuity and improved binocular vision. LASIK appears to be a safe surgical procedure for children over 9 years of age.

Adolescent↗
PubMed1987

[Convergent strabismus in children. Clinical aspects and treatment].

The classification of convergent strabismus of the child, "esotropies", is mainly based upon the age of appearance. It is indeed fundamental to distinguish the early esotropies where the recovery of binocular vision is impossible and the orthoptic reeducation unnecessary, from the late forms where orthoptic reeducation and treatment could achieve the recovery of the binocular vision.

Child, Preschool↗
PubMed1982

[Primary divergent strabismus: Reflections after thiry years experience of treatment (author's transl)].

Certain specific points concerning the treatment of divergent strabismus are discussed, particular emphasis being placed on the importance of the sensorial element, which must be restored to normal levels in order to obtain complete recovery. Orthoptic reeducation is a highly effective necessary stage, and should be attempted in all its forms. Excellent or good results have been obtained in 85 p. cent of cases, 1 half of these by the use of orthoptic exercises alone.

Humans↗
PubMed1995

A new protocol for the optometric management of patients with reading difficulties.

Research by Evans et al. (Ophthal. Physiol. Opt. 15, 481-487, 1995) has demonstrated a correlation between visual processing and ocular motor factors in people with specific reading difficulties (dyslexia). In addition, research by Wilkins et al. (Ophthal. Physiol. Opt. 14, 365-370, 1994) has shown that some people with dyslexia will benefit from a reduction of perceptual symptoms of discomfort and distortion if they use individually prescribed coloured filters. Three examples of the dyslexic patients who attend at the Institute of Optometry clearly demonstrate the importance of full investigation of ocular function, including the assessment of the effect of colour on visual perception. All three patients presented with similar symptoms of asthenopia when reading. Symptoms were alleviated for the first patient by use of orthoptic treatment of an exotropia with intermittent suppression. With the second patient, ocular motor functions were found to be within acceptable limits and relief of symptoms was obtained by the prescribing of lenses of a specific chromaticity. For the third patient, both orthoptic intervention and the use of specifically tinted lenses were necessary to relieve the visual difficulties that were being experienced. By taking advantage of recent research and developments in optometric instrumentation, it is possible for some of those with dyslexia to receive considerable benefit from optometric intervention.

Adolescent↗
PubMed2000

Vertical and cyclotorsional deviations following peribulbar anesthesia.

BACKGROUND: Motility disorders may occur consecutive to peribulbar anesthesia. The underlying pathology is still debated. The aim of the study was to contribute to the discussion by a meticulous orthoptic examination of a series of patients. METHODS: In a series of 16 patients with diplopia after peribulbar anesthesia, measurements of the angle of squint in the nine directions of gaze, Bielschowsky's headtilt test and motility analysis were performed. The findings were discussed with regard to the possible types of muscular lesions. RESULTS: Hypotropia and deorsoadduction accompanied by relatively small cyclotropia were found in all cases. Bielschowsky's head-tilt test mostly revealed neutral findings. CONCLUSION: The findings were discussed under the hypothesis of a fibrotic muscular change in the superior oblique and inferior rectus muscle. This hypothesis turned out to be concordant with the orthoptic measurements, implying that treatment of the disorder should consist in low-dosage recession of the fibrotic muscles, which in our experience was rewarding.

Aged↗
PubMed2007

Long-term results of surgery in childhood glaucoma.

PURPOSE: The aim of this study is to assess the functional results and morphological parameters in children surgically treated for glaucoma. METHODS: Data from 43 patients and 68 eyes who were operated in our department between 1990 and 2002 were collected. This retrospective trial included primary congenital glaucoma (n=36), and secondary glaucoma (n=7) in Rieger-Axenfeld syndrome and Sturge Weber syndrome. Intraocular pressure (IOP), axial length of the eyeball, visual acuity, refractive errors and orthoptic status were analysed. RESULTS: The age of patients at the first surgery was 6.0 +/- 5.3 months (range 0.7 to 28.0 months). The mean period of follow-up was 57.3 +/- 36.8 months (6.0-161.0). The mean number of surgical procedures performed on one eye was 2.5 +/- 2.4 procedures (1-11). The mean IOP before the first surgery was 31.0 +/- 7.9 mmHg (17.5-52.0), and was 15.0 +/- 3.9 mmHg (7.0-28.0) at the last visit. 49 eyes (72.1%) did not need any further medical treatment after the last surgical procedure. The IOP was 18 mmHg or lower without medication in 29 eyes (42.6%) after just one surgical procedure (21 trabeculotomy, 8 combined trabeculotomy/trabeculectomy with or without mitomycin-C). At the first examination, the mean axial length of the eyeball was 22.6 +/- 1.8 mm (the mean normal value at this age is 20.3 +/- 0.7 mm), and was 24.4 +/- 2.0 mm at the last visit (the mean normal value at this age is 22.2 +/- 0.6 mm). The best corrected visual acuity at the last visit was 0.25 +/- 4.6 lines; the normal range of visual acuity at this age is from 0.4 +/- 4.0 lines to 0.8 +/- 3.0 lines. Visual acuity was 0.32 or more in 53.0% of the eyes. Visual acuity was lower than 0.1 in only 15.2% of the eyes. Myopia was present in 57.4% of the eyes with a mean spherical equivalent of -6.1 +/-3.9 dioptres. 15 patients (34.9%) developed strabismus. 22 patients (51.2%) were treated with part-time occlusion. Binocular function as assessed with the Lang-1 test was positive in 17 of 30 patients (56.7%). CONCLUSIONS: Although a good long-term IOP-control can often be achieved in childhood glaucoma, the visual acuity remains below the normal range in most cases despite close orthoptic follow-up.

Alkylating Agents↗
PubMed1996

Poly(L-lactide) implants for repair of human orbital floor defects: clinical and magnetic resonance imaging evaluation of long-term results.

PURPOSE: The purpose of this study was to evaluate the long-term outcome of repair of orbital floor defects in patients with resorbable as-polymerized poly(L-lactide) (PLLA) implants and to determine whether these patients showed symptoms that could be indicative of the presence of a late tissue response. PATIENTS AND METHODS: Six patients (four women, two men; mean age, 39 years; range, 18 to 67 years) treated with PLLA implants for orbital floor fractures were recalled for follow-up examination after a period ranging from 3 1/2 to 6 1/2 years. The examination consisted of an interview and a physical examination, including an ophthalmologic and orthoptic consultation. For evaluation of the orbital tissues, coronal spin echo T1- and T2-weighted magnetic resonance images (MRIs) were made through both orbits. RESULTS: None of the patients reported any problems in the years preceding the follow-up examination that might have indicated complications. Clinical examination of the operative sites revealed no abnormalities. At ophthalmologic and orthoptic consultation, normal eye function, without diplopia or restriction of motility, was found in all patients. The MRIs showed no indication of an abnormal or increased soft tissue reaction in the orbital region. CONCLUSIONS: Based on the results of this study, it can be concluded that PLLA orbital floor implants have the potential for successful use in repair of human orbital floor defects.

Adolescent↗
PubMed1992

Ocular manifestations of Noonan syndrome.

Noonan syndrome is a genetic condition inherited in an autosomally dominant manner, characterised by congenital heart disease, short stature, abnormal facies and the somatic features of Turner's syndrome, but a normal Karyotype. The ophthalmological and orthoptic findings on 58 patients with Noonan syndrome are reported. External features were hypertelorism (74%), downward sloping palpebral apertures (38%), epicanthic folds (39%) and ptosis (48%). The orthoptic examination revealed strabismus in 48%, refractive errors in 61%, amblyopia in 33%, and nystagmus in 9% of cases. Sixty-three per cent of cases had anterior segment changes consisting of: Prominent corneal nerves (46%), anterior stromal dystrophy (4%), cataracts (8%) and panuveitis (2%). Fundal changes occurred in 20% of the study group, including optic nerve head drusen, optic disc hypoplasia, colobomas and myelinated nerves. Forty-seven per cent required non surgical treatment and a further 16% had undergone surgery for strabismus or ptosis. Only three patients had no visual defects. With such a high incidence of ophthalmic abnormalities it is clearly important that children with Noonan syndrome are screened by an ophthalmologist at an early age.

Adolescent↗
PubMed1996

Preschool vision screening: a prospective comparative evaluation.

We have reviewed the results of a pilot study of preschool screening by orthoptists for vision defects which was introduced in Newcastle in 1987. We have compared the visual outcomes, at age 7 years, of children who were screened at age 3 years by either orthoptists, health visitors or general practitioners in three matched, geographically defined cohorts. Manifest, large angle strabismus presented at the same age, and in roughly equal numbers in each cohort. Orthoptic screening detected many more cases of amblyopia associated with microtropia and anisometropia, but the b overall amblyopia prevalence at age 7 years was similar in each cohort. This study does not provide evidence to support the nationwide introduction of primary orthoptic preschool vision screening, and highlights the need for a prospective treatment trial of amblyopia associated with microtropia and anisometropia.

Amblyopia↗
PubMed2002

Psychosocial and clinical determinants of compliance with occlusion therapy for amblyopic children.

AIMS: The objective of this study was to determine the extent that psychosocial and clinical variables influence parental compliance with occlusion therapy (eye patching) in children with amblyopia. METHODS: Children (n = 151) receiving occlusion therapy (eye patching) for the treatment of amblyopia were recruited from five orthoptic clinics in Bristol, UK. Parents completed a questionnaire based on Rogers' (1983) Protection Motivation Theory (PMT). The parents (n = 105) were also followed up 2 months later. Clinical data, including measures of visual acuity, were also recorded. Compliance with eye patching was assessed through self-report accounts of parents. Stepwise regression analyses were used to determine the factors predictive of compliance with eye patching. RESULTS: Self-reported compliance with eye patching at study entry revealed that only 54% of parents were achieving orthoptists' recommendations to patch their child. Perceived self-efficacy was positively associated with compliance and perceived prohibition of the child's activities were negatively associated with compliance. At follow-up, past behaviour accounted for the largest proportion of explained variance in patching behaviour followed by response efficacy, and prohibition of the child's activities. CONCLUSION: The present findings may serve to inform interventions aimed at enhancing current orthoptic practice to improve compliance in amblyopic children. The importance of 'self-efficacy' and past behaviour suggests that consultations with parents exhibiting higher levels of success with patching may elicit strategies that could be shared with parents experiencing difficulties with patching their children. In addition, it is possible that the perceived efficacy of the treatment could be enhanced if orthoptists emphasised evidence of improvements in visual acuity which may, in turn, foster the maintenance of eye patching.

Amblyopia↗
PubMed2000

[Vertical diplopia after cataract operation].

PURPOSE: Presentation and analysis of patients with vertical diplopia appearing after cataract surgery in retrobulbar anesthesia. SUBJECTS AND METHODS: Between 1990 and 1998 9 Patients with vertical diplopia following cataract surgery in retrobulbar anesthesia were studied in our Orthoptic Department. Each patient had complete orthoptic examination with Hess-screen-test. Additionally, some patients underwent neuroradiologic imaging and forced-duction testing. RESULTS: We subdivided the patients in a group of 4 patients with hypertropia and of 5 patients with hypotropia of the operated eye. All hypotropias were left-sided. Seven patients showed an overaction of the involved muscle without regression. Seven patients underwent surgery of a vertical muscle. Only 1 patient needed prismatic therapy postoperatively. The other 2 non-operated patients were satisfied with prisms alone. CONCLUSIONS: The proposed pathogenesis of vertical diplopia in these cases is fibrosis and contracture of the injured muscle, which could be due to anesthetic myotoxicity after direct injection into the muscle or to an intramuscular hemorrhage. On the other hand hypertropia could be a result of placement of bridle sutures. We discuss prevention and therapy of such complications.

Aged↗
PubMed2002

[Amblyopia of the fellow eye in assumed unilateral congenital fibrosis syndrome].

BACKGROUND: Amblyopia of the ptotic eye in spite of head posturing and of the fellow eye in ptosis with motility disorders are well known. We emphasize the importance of exact ophthalmological and orthoptic examinations to avoid amblyopia in both ptosis and fellow eye, even in cases of mild ptosis, especially if they are combined with motility disorders. PATIENT: A 5 year-old girl presented to our outpatient clinic because of ptosis of the left eye and hypertropia of the right eye. Visual acuity of the right eye was 0.32 and of the left ptotic eye 1.0. Cycloplegic retinoscopy showed + 2.0 sphere in both eyes. Ocular motility showed a mild reduction of elevation of the left eye in ad- and abduction. This led to the diagnosis of congenital fibrosis syndrome of the inferior rectus muscle of the left eye. Due to the preferred fixation with the left ptotic eye and the consecutive deviation of the fellow eye amblyopia of the right eye had developed. Occlusion therapy of the left eye resulted in an improvement of visual acuity of the right eye to 0.9 and centralisation of fixation within one month. CONCLUSION: Even children with mild ptosis, especially in combination with motility disorders, require a complete ophthalmological and orthoptic examination to avoid amblyopia also of the fellow eye.

Blepharoptosis↗
PubMed1997

[Photoscreening for early detection of amblyogenic eye changes].

BACKGROUND: Congenital and early acquired ocular changes impairing the optic input induce amblyopia when left untreated. Amblyopia treatment must start early to be efficient. Therefore it seems necessary to employ screening tests in preverbal childhood. PATIENTS AND METHODS: The reliability of two commercially available photoscreening devices, the "Visiscreen 100" (Vision Research Corp.) and the "MTI-Photoscreener" (Medical Technology Inc.), was tested. 180 children from a kinder-garten and 120 infants from our outpatient clinic were screened. The results were compared to the findings of a full ophthalmologic and orthoptic examination. RESULTS: The efficacy of the photoscreening depended on the skill of the examiner and on the age of the children tested. The rate of interpretable photographs was 94% in the older group and 63.3% in the infants. The mean sensitivity for detection of amblyogenic factors was 63% in the older and 80% in the infant group. The mean negative predictive value was 90%, and 75%, respectively. CONCLUSION: Modern photoscreening techniques can help to detect amblyogenic factors in early childhood. However, in addition to the non-interpretable photographs, about 20% of the affected children are missed. Therefore, photoscreening cannot be recommended for countries with a high number of ophthalmologists, such as Germany. Instead, an ophthalmologic and orthoptic investigation in early childhood would be preferable.

Amblyopia↗