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At least 469 records · Page 26Linked to original sources
PubMed2004

[Two cases of retroperitoneal liposarcoma arisen from perirenal fat tissue, which could not be diagnosed preoperatively].

We report two cases of retroperitoneal liposarcoma arisen from the perirenal fat tissue, which could not be diagnosed preoperatively. Case 1 is a 58-year-old male. He complained of left flank tumor. Computed tomography and magnetic resonance image showed a mass over 10 cm that contained fat components in the retroperitoneal space. The tumor was resected with left nephrectomy and histological examination revealed well differentiated liposarcoma. As adjuvant therapy, he received chemotherapy and 30 months has passed uneventfully. Case 2 is a 70-year-old male. Screening ultrasonography revealed incidental retroperitoneal tumor. With clinical diagnosis as non-functioning adrenal tumor, he received left nephrectomy. The pathological diagnosis was well differentiated liposarcoma, sclerosing type. No adjuvant therapy was performed. He has stopped visiting our clinic due to aggravation of heart disease. The characteristics of the images of the two cases were different despite the histological resemblance. This difference was considered to be due to the difference in the distribution of lipomatous tissue in each patient.

Adipose Tissue↗
PubMed1992

[Dedifferentiated liposarcoma. A clinico-pathologic study of 6 cases].

During a period of 15 years, 6 cases of dedifferentiated liposarcomas were found among 542 cases of adult soft tissue sarcomas, 77 of which were liposarcomas. They were huge tumors of the retroperitoneum, containing distinct areas of well-differentiated liposarcoma most often of sclerosing type and malignant fibrous histiocytoma or undifferentiated sarcoma most often of high grade malignancy. Immunohistochemistry on the dedifferentiated component showed a positivity with anti-vimentin and alpha-1-antichymotrypsin in 5 cases and with anti-alpha smooth muscular actin in 4 cases. Three patients developed local recurrence and a fourth one quickly died with bone metastasis. Other types of dedifferentiated sarcomas, the process of dedifferentiation and links between malignant fibrous histiocytoma and dedifferentiated sarcomas are discussed.

Aged↗
PubMed2005

[A case of retroperitoneal liposarcoma arising from the renal capsule].

We treated a case of retroperitoneal liposarcoma arising from the renal capsule by operation and adjuvant radiation. A 61-year-old woman was referred to our department for treatment of a right renal tumor revealed by computed tomography (CT). CT, magnetic resonance imaging and angiography demonstrated a large renal tumor with fat tissue, fed from the renal capsular artery. Right radical nephrectomy was performed on February 4, 2003. The tumor was diagnosed histopathologically as well differentiated liposarcoma arising from the renal capsule. The surgical margin was positive. Therefore, the patient was given 50 Gy of radiation postoperatively. There have been only 18 reports of liposarcoma arising from the renal capsule in Japan.

Female↗
PubMed2005

Primary mesenteric liposarcoma of jejunum: presentation like a cystic mass.

This report describes a rare case of intra-abdominal liposarcoma in a 67-year-old woman. The patient presented at Internal Medicine Unit in May 2004, to study of thyroid pathology. The clinical examination was normal, except for the finding of an asymptomatic mass in the abdomen. The patient knew the existence of tumor since time ago, but she confesses to have only occasional discomfort. In the abdominal ultrasonography a solid mass with large cystic component was detected but relation with other organs was not clear. Computed tomography revealed the presence of a mass with solid and cystic components, in contact with small intestine in the left side of abdomen. A complete resection of tumor arising from mesentery of jejunum was performed successfully with end to end anastomosis. The gross specimen was lobulated and measured 8.5 x 7.5 cm. The histopathology analysis showed proliferating lipoblasts with irregular nuclei on a myxoid background, with plexiform vascular pattern, characteristics belongs to myxoid type liposarcoma. The patient is alive and well one year after removal of tumor. The uncommon site and the exceptional cystic morphology of tumor are discussed, and so it must be included the primary mesenteric liposarcoma in the differential diagnosis of intra-abdominal tumors with cystic large areas.

Aged↗
PubMed2006

[A case of liposarcoma of the sigmoid colon mesenterium successfully treated with chemotherapy].

We report a case of postoperative recurrence of liposarcoma of the mesenterium successfully treated by chemotherapy using ifosfamide (IFM) and cisplatin (CDDP). A 58-year-old man presented with a strange feeling in the lower abdomen. Enhanced computed tomography showed enhanced non-epithelial tumor in the pelvic space. The tumor moved on palpation, so we diagnosed liposarcoma from the mesenterium, and resected the tumor on 22 August, 2002. The pleomorphic liposarcoma was 11 x 14 x 7 cm, growing from the mesenterium of the sigmoid colon, and weighed 640 g. We performed re-operation due to pelvic recurrence on 24 March, 2003. On 18 September of the same year, when we performed re-operation again for pelvic recurrence, there were so many recurrences on the mesenterium of small intestine that resection was impossible. We started chemotherapy 3 days later using 3.0 g/body IFM from 1 October 2003, together with 1,800 mg/body mesna for prevention of hemorrhage cystitis. We continued chemotherapy using 3.0 g/body/day IFM together with 1, 800 mg/body/day mesna on an outpatient basis, upon his weekly visit to the hospital. Patient remission was shown by abdominal enhanced computed tomography on 10 December. Some grade 2 alopecia and grade 2 leukopenia occurred, so we changed to chemotherapy once every two weeks. Then, it continued to decrease, without any side effects. The response appeared to be complete on computed tomography in August 2004, and we have been continuing the same chemotherapy without recurrence.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

[Mesocolon liposarcoma: a case report].

Liposarcoma is the second most common soft tissue sarcoma in adults after fibrosarcoma. Extremities and retroperitoneum are the most common sites. Intraabdominal and particulary mesocolic liposarcoma is a rare localisation. We report the case of a 64-year-old woman with a localized grade 1 liposarcoma of the right mesocolon treated by an extended right hemicolectomy. No further treatment was done because of the low grading and the disease-free margins. The patient is without any evidence of recurrence after one year.

Female↗
PubMed2006

[Local recurrence of spermatic cord liposarcoma: a case report].

A 46-year-old man had undergone radical high orchiectomy because of a tumor of the right spermatic cord. Pathological diagnosis was atypical lipomatous tumor. Six years later, he had asymptomatic swelling in his right groin. Local recurrence was suspected, and surgical resection of the tumor with a sufficient surgical margin was performed. Pathological diagnosis was well-differentiated liposarcoma, sclerosing type. Ten cases of recurrent spermatic cord liposarcoma, including the present case, have been reported in Japan. Because of the possibility of local recurrence, spermatic cord liposarcoma needs strict and long-term follow up.

Genital Neoplasms, Male↗
PubMed2006

[A case of myxoid liposarcoma in the right inguinal region: a case report].

We report a case of myxoid liposarcoma developed in the right inguinal region. A 45-year-old man visited our hospital with a chief complaint of painless right inguinal mass. He was diagnosed with right direct inguinal hernia for the first time and received a hernia repair. However, the size of the inguinal mass increased gradually after the operation. Then, the tumor was re-evaluated by imaging study such as ultrasonography, computed tomography and magnetic resonance imaging. A fatty mass 4.0 cm in diameter was demonstrated and the tumor was diagnosed as a liposarcoma preoperatively. In addition to the right high orchiectomy, surrounding fatty tissue was also removed at the time of the operation. Histological examination revealed a myxoid liposarcoma and the existence of several daughter regions outside the pseudo-capsule. Right spermatic cord and testis were intact. Postoperatively, he received 54 Gy dose of radiation therapy to right inguinal region for the prevention of the local recurrence of the disease.

Abdominal Neoplasms↗
PubMed2006

Giant mediastinal liposarcoma: a case report.

Liposarcomas are extremely rare in the mediastinum. They may achieve considerable size before causing any symptoms. Mediastinal liposarcomas may invade surrounding structures like the pericardium or the superior vena cava. Complete surgical excision is the optimal treatment in resectable cases. Excision of adjacent structures like the pericardium may be needed if the tumor infiltrates them. We report on a case of a giant liposarcoma of the mediastinum involving both hemithoraces and extending into the neck, which was successfully managed by complete surgical excision.

Humans↗
PubMed1991

Derangement of adipose tissue: a case report of multicentric retroperitoneal liposarcomas, retroperitoneal lipomatosis and multiple subcutaneous lipomas.

No aetiological factors are at present known in the pathogenesis of liposarcomas. Benign lipomatous disorders, such as lipomas and lipomatosis, generally do not predispose to the development of liposarcomas. A case is presented of a patient with multicentric retroperitoneal liposarcomas, associated with retroperitoneal lipomatosis and preceded by a long history of multiple subcutaneous lipomas. In the literature this combination has not been described. This rare combination of lipomatous disorders seems to indicate a common derangement of adipose tissue.

Humans↗
PubMed1990

Bone tumors of mixed origin: osteo-liposarcoma and osteo-rhabdomyosarcoma.

1. A complete perusal of the literature revealed twenty cases of primary liposarcoma of bone acceptable as such to the authors. These were tabulated as to location and age. 2. Eight cases of osteo-liposarcoma, primary in bone, were encountered in the literature and an additional case was reported by the authors. 3. The authors described for the first time in the literature a new primary tumor of bone of mixed origin: osteo-rhabdomyosarcoma. After careful perusal of the literature they added three additional cases: two cases, previously reported as primary rhabdomyosarcoma of bone, which on careful evaluation of the radiographs in said publications and the paucity of microphotographs they considered to be osteo-rhabdomyosarcomas, and the other case, previously reported as malignant mesenchymoma of the sternum following radiotherapy for breast cancer. 4. The authors prefer to classify these tumors (osteo-liposarcoma and osteo-rhabdomyosarcoma) as "Tumors of Mixed Origin" and not as "Malignant Mesenchymomas". 5. A complete review of the literature revealed 219 reported "dedifferentiated" chondrosarcomas, or chondrosarcomas "with additional mesenchymal component", among which only nine (9) contained a bona fide rhabdomyosarcomatous component. The rest exhibited other mesenchymal tumors as osteogenic sarcoma, fibrosarcoma, malignant fibrous histiocytoma, angiosarcoma, and undifferentiated sarcoma. The authors recommend to continue classifying these tumors as chondrosarcomas with additional mesenchymal component or even as "dedifferentiated" chondrosarcomas but not as malignant mesenchymomas.

Adolescent↗
PubMedDate not supplied

[Paratesticular liposarcoma of the spermatic cord].

Funiculus liposarcoma is a very uncommon tumor. Most cases have a low degree of malignancy. Inguinal orchiectomy with a wide local excision is the appropriate treatment. Liposarcoma presurgical diagnosis is very infrequent and ultrasonography is the method that can provide some help to locate it. Currently, chemotherapy indication is unclear. Due to recurrence, specially of local foci, being a possibility a periodical follow-up is necessary in these patients. Nowadays, local recurrences are treated with repeated ample local excisions and radiotherapy. This work reviews the literature and presents a new case of round cells liposarcoma of the funiculus.

Genital Neoplasms, Male↗
PubMed1990

Primary liposarcoma of the heart.

We report the eleventh illustrated case of primary liposarcoma of the heart in a 28-year-old man. The tumor arose from the mitral valve and the left ventricle and was revealed by a solitary brain metastasis 1 year before. The primary tumor and the metastasis were surgically removed. The cardiac and brain neoplasms were myxoid liposarcoma, as confirmed by histochemical, immunohistochemical, and ultrastructural studies. Although review of the literature points out the poor survival of patients with malignant liposarcoma of the heart, no recurrence or metastasis was observed after a 6-month follow-up.

Adult↗
PubMed1989

[Spontaneous rupture of a renal liposarcoma].

The authors describe a rare case of spontaneous rupture of a renal liposarcoma which imitated the clinical picture of an acute abdomen. Urgent transabdominal left nephrectomy was performed. The entire lower half of the kidney was altered by the tumour and ruptured and there was an extensive perirenal and retroperitoneal haematoma. The histological finding confirmed the presence of a primary renal liposarcoma. This is the first case of spontaneous rupture of a liposarcoma of the kidneys described in our literature and the second case in the world literature. The patient survives now for eight years after operation and is in a good condition.

Abdomen, Acute↗
PubMed1989

[The retroperitoneal liposarcoma: a case report].

A 62-year-old woman was admitted to our hospital because of a mass in the right abdomen. Ultrasonography, aortography and computed tomographic (CT) scanning revealed the right kidney displaced by a huge and avascular mass containing fatty tissue. Also magnetic resonance imaging (MRI) indicated that it was contained of lipomatous tissue and demonstrated the mass occupying the entire right abdominal cavity. The tumor including the right kidney was resected, following diagnosis of the retroperitoneal tumor. The exercised tumor measured 28 X 22 X 18 cm and weighed 2,010g. The histological diagnosis was well-differentiated liposarcoma. She has been healthy for three months following postoperative chemotherapy. Many reports have been made on the ultrasonographic and CT appearance of retroperitoneal liposarcoma, but few have been made on the MRI appearance. According to our case, imaging diagnosis by MRI also seems to be useful in making a histological diagnosis of liposarcoma.

Combined Modality Therapy↗
PubMedDate not supplied

Liposarcoma of pleural cavity with recurrence as malignant fibrous histiocytoma.

The case of a 54-year-old male, with a massive right pleural liposarcoma weighing over 3200 g, is presented. The tumor was found by light and electron microscopy to be of well-differentiated and pleomorphic subtypes, and it apparently represents the sixth reported case of liposarcoma primary to the pleura. Two years after excision of the primary tumor, it recurred as a neoplasm with histologic and ultrastructural features characteristic of malignant fibrous histiocytoma. The histogenetic and pathologic implications of the above findings are discussed, and the literature regarding intrathoracic liposarcoma and malignant fibrous histiocytoma is reviewed.

Cell Nucleus↗
PubMedDate not supplied

[Liposarcoma of the ischiorectal fossa, an unusual tumoral site].

The main locations of the liposarcoma, the most common of the soft tissue sarcomas, are the lower limbs and the retroperitoneal space. We report the case of a 58 year-old male patient presenting with a huge and painless mass of the left fossa ischiorectalis. Preoperative tests and CT-scan of the pelvis evoked the diagnosis of liposarcoma, laminating and lifting the rectum and bladder. Visceral walls were respected. The patient underwent a en-bloc excision of the tumour by a combined perineal and abdominal route. Pathological examination of the mass (1.7 kg) confirmed the diagnosis of well differentiated liposarcoma. No further treatment was initiated, but, because of the high risk of local recurrence, the patient has been placed under a close follow-up schedule.

Humans↗
PubMedDate not supplied

Cytologic features of well-differentiated sclerosing liposarcoma in aspirated samples.

The histologic, cytologic and ultrastructural features of two cases of a rare variant of liposarcoma, the well-differentiated sclerosing type, are presented. These tumors are characterized by lipoblasts (in different stages of development), atypical fibroblasts, multinucleated floret cells, lipocytes and delicate, dispersed collagen. The differential diagnosis includes other types of liposarcoma and three benign lipomatous lesions: the pleomorphic lipoma, the atypical lipoma and the spindle cell lipoma. The latter three neoplasms are composed of fibroblasts, lipocytes and coarse collagen and may have typical lipoblastlike or fibroblastic cells. Given the difficulty in distinguishing these lesions, both cytologically and histologically, the clinical presentation and the tumor location become essential in rendering the diagnosis of sclerosing liposarcoma.

Aged↗