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[Biological effects of suture materials].

Suture materials have some important biological effects which may influence the rate of early and late anastomotic complications. The risk of dehiscence is increased by those materials stimulating a local phlogistic reaction, therefore delaying the activation of the repairing process. Not absorbable sutures cause a chronic granulomatous reaction that may result in cicatricial stenosis. Experimental studies suggest surgical sutures to act as a nidus for adhesions and growth of exfoliated tumor cells. This property is greater for the natural and braided materials.

Anastomosis, Surgical↗

Clear-cell epithelial neoplasms of the large intestine.

We report four cases of primary clear-cell adenoma and adenocarcinoma of the large intestine. The neoplasms grossly resembled ordinary colonic adenomas and adenocarcinomas but microscopically were composed of uniform cells with optically clear cytoplasm. Mucin stains were negative, and the clear nature of the cytoplasm was due to glycogen accumulation. Areas of transition between normal colonic epithelial constituents and the clear-cell lesion were observed. Three of the four cases stained strongly positively for carcinoembryonic antigen. These lesions are apt to give rise to considerable diagnostic confusion and, in particular, resemble metastatic renal cell carcinoma. The usual strong positive carcinoembryonic antigen reaction is helpful in establishing this diagnosis.

Acid Phosphatase↗

RETICULUM CELL SARCOMA OF THE SMALL BOWEL AND STEATORRHOEA.

This series presents further evidence for an association between reticulosis of the intestine and steatorrhoea. Although some patients have a definite past history of gluten enteropathy, it seems likely that in certain patients the reticulosis itself is the primary cause of the steatorrhoea.

Ascorbic Acid↗

Small bowel schwannoma with diffuse subcutaneous lipomatosis. Case report and literature review.

A case of a small-bowel schwannoma with diffuse familiar lipomatosis is described. This case underlines the rarity of the neoplasm and its probably chance association with subcutaneous lipomatosis. The intestinal neoplasm was diagnosed preoperatively by upper gastrointestinal endoscopy and a small-bowel enema; computed tomography scan confirmed the intestinal lesion. Attention is focused on the morphological features of intestinal schwannomas and their biological behaviour.

Humans↗