[Cardiac interval measurement in the diagnosis of tubal sterility].
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Evaluation of the infertile couple involves confirming the diagnosis of infertility based on history and a review of coital practices. A complete examination should include the following components: general evaluation, history, physical examination, assessment of ovulatory factor, tubal factor, peritoneal factors, uterine factors, and cervical factor, and assessment of male factor.
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Interstitial fallopian tube obstruction (IFTO) occurs in 15% of hysterosalpingograms (HSG) performed for infertility. Conventional HSG or laparoscopy may not differentiate cornual spasm or other temporary cause from true obstruction. We used transcervical cannulation of the proximal oviduct with a 3-F Teflon catheter and flexible guidewire 0.018 inch (0.043 cm) in diameter under hysteroscopic or fluoroscopic guidance to evaluate IFTO in 28 patients. Fluoroscopic catheterization techniques with selective salpingography demonstrated patency in 84% of obstructed tubes. Hysteroscopic cannulation with direct visualization by laparoscopy or laparotomy was successful in 92%. In one patient, perforation of the isthmus occurred without sequelae. Transcervical coaxial cannulation of the proximal oviduct is an effective method for evaluating cornual obstruction.
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There will be demonstrated a method in order to contrast the cavum uteri and the uterine tubes by means of a x-ray TV amplifier in combination with simultaneous intrauterine pressure monitoring. We could demonstrate that measuring the intrauterine pressure during continuous flow of radio-opaque material at hysterosalpingography results in additional informations about tubal patency.
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Hysterography and hysteroscopy are diagnostic techniques currently utilized in searching for intrauterine defects that can cause infertility. The purpose of this paper is to describe the basic procedures, discuss their indications and compare results obtained in the infertile patient.
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A series of 336 infertile patients were evaluated by tubal insufflation, hysterosalpingography, and laparoscopy. The treee procedures revealed patient tubes in 175 patients (52%) and occluded ones in 44 (13%) patients. Thus results with the three methods agreed in 219 patients (65%). False results of tubal insufflation were 18.5% (9.8% false negative and 8.6% false positive). False negative results of hysterosalpingography are 9.5% and false negative results of laparoscopy are 6.8%. Additional pelvic pathology detected by laparoscopy was seen 60 patients (17.8%). Pelvic adhesions (36 patients) and endometriosis (24 patients) were the pathologic processes most commonly missed by hysterosalpingography. Suspected pelvic pathology was corrected by laparocopy in nine cases (2.6%). Double evaluation, both by hysterosalpingography and laparoscopy was needed in 30% of the infertile patients, and therefore both methods should be considered supplementary. Provided that both hysterosalpingography and laparoscopy can be performed, tubal insufflation, since it gives no further information, should be abandoned or discrepant results rejected.
For a period of time routine hysterosalpingography and laparoscopy were carried out in every patient complaining of more than 2 years of primary infertility. The records of 433 such patients were retrospectively evaluated according to their clinical aspects. Complete agreement between the two diagnostic methods was found in 70.9% of this unselected population. Almost 50% of the population had some abnormalities in either hysterosalpingography or laparoscopy. According to the patient's past history, pelvic examination, and the duration of infertility, the unselected infertile population was classified into a) high risk infertility and b) low risk infertility. High risk infertility patients had (P less than 0.01) greater abnormal findings at both hysterosalpingography and laparoscopy. In this high risk group we recommend early laparoscopy and the postponement of hysterosalpingographic investigation for patients with suspected cornual occlusion or destruction of ampullary rugae (valuable in assessing tubal damage). Low risk infertility patients had (P less than 0.01) low abnormal findings at both hysterosalpingography and laparoscopy, and in these patients hysterosalpingography does not discriminate the group of higher abnormal laparoscopic findings. Hysterosalpingography can be initially indicated as a less invasive investigation in the low risk group. We conclude that clinical data are very valuable in the selection of infertile patients for early or late laparoscopy.
Cellular components in peritoneal fluid of infertile patients with and without endometriosis were evaluated in 102 patients with Wright's-Giemsa and Papanicolaou stains. The secretory activity of these cells was studied indirectly by assaying acid phosphatase, prostaglandin (PG) F2 alpha and PGE2 and complement components C3c and C4. The results showed that macrophages and lymphocytes were the dominant cells in peritoneal fluid of these patients. These cells were significantly increased in endometriosis patients, as compared with control subjects. In addition, peritoneal fluid acid phosphatase, PGF2 alpha and PGE2, and complement components C3c and C4 were significantly increased in patients with endometriosis. These cellular changes and their activation in peritoneal fluid may explain infertility associated with endometriosis.