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[Treatment of chronic skin ulcers in the elderly. Descriptive study on the use of a hydrocellular dressing].

INTRODUCTION: There are a wide variety of products to use to treat skin ulcers. Knowing the correct usage and application of each product aids in choosing the most appropriate for elderly patients. OBJECTIVE: To evaluate the use of a hydrocellular dressing and its clinical test results. METHODS AND MATERIALS: This descriptive, prospective study begun on 6/X/97 and finished on 1/XII/97 included all the moderate or severely oozing skin ulcers, those classified as stage II, III, or IV, among the elderly at a home for them. This study discarded ulcers which barely bled; however, regional or systemic infection-related ulcers were included. RESULTS: 20 skin ulcers were analyzed. At the start, these covered an average surface are of 11.76 cm2 (DT 14.44), with an average severity index of 23.79 (DT 35.81). At the end of this study, the average area was 7.92 cm2 (DT 12.11) and the average severity index was 14,60 (DT 27,18). 7 ulcers, or 35%, had epithelized completely. During the 768 day length of this study, 290 dressings were applied. 100% of these were evaluated as easy to apply and remove; patients indicated an absence of pain; no dressing was disjoined when changed and therefore left no residue in the injured area. CONCLUSIONS: The dressing studied is effective for local treatment of all types of skin ulcers, regardless of their condition; this dressing reduces the number of changes necessary, especially in curing oozing ulcers; and finally, this dressing is easy to apply and aids in keeping the patient in good spirits.

Bandages, Hydrocolloid↗

[Wound dressings in chronic wounds].

Hydroactive wound dressings retain exsudate in the wound region or incorporate wound exsudate by gel formation. They create the local environment for moist wound healing which is experimentally and clinically characterized by accelerated reepithelialization, inflammatory reaction and angiogenesis as well as reduced wound pain and wound infection rates. Clinically relevant product groups of hydroactive wound dressings (hydrocolloids and hydropolymers, semipermeable films, calcium alginates) are distinct as to chemical structure, physical properties and functional characteristics in local wound treatment. Between the product groups, there are considerable differences with respect to inflammatory reactions at the wound bottom, absorption of exsudate, occlusion properties, wound edge adherence, adaptability to the wound shape and material integrity of wound dressings. Experimental and clinical results of moist wound treatment by hydroactive wound dressings such as hydrocolloids and hydropolymers, semipermeable films or calcium alginates reveal a wide range of local response on the different types of dressings. They offer the opportunity of therapeutic differentiation. To elucidate the differential indication for different product groups of hydroactive wound dressings in local treatment of chronic wounds, additional experimental and clinical research is required.

Bandages↗

[Heel pressure ulcers. Comparative study between heel protective bandage and hydrocellular dressing with special form for the heel].

INTRODUCTION: The heels, together with the sacra area, are one of the most frequent spots where pressure sores appear here in Spain. Any preventive measure against pressure sores on heels needs be oriented towards two main objectives: effective relief of pressure and its compatibility with localized care and skin inspection in order to detect lesions early on at least once a day. PATIENTS, MATERIALS AND METHODS: The authors planned a comparative, multi-centered, open, labeled and controlled study in which patients were assigned to two groups receiving these treatments: one received traditional preventive pressure sore treatment and a protective bandage on their heels while the other used a special Allevyn Heel hydrocellular dressing to protect their heels. The patients took part in this study over an eight week period. The response variable used to determine the effectiveness of the preventive measure in this study was the appearance of pressure sores. RESULTS: At the beginning, 130 patients were included in this study, 65 in each one of the treatment groups. In the bandage group, 50 patients finished this study while 61 in the dressing group finished this study. The appearance of pressure sores in the protective bandage group occurred in 44% of the patients, 22 out of 50, while in the dressing group, the occurrence rate was 3.3%, 2 out of 61 patients with a value of "ji" squared p < 0.001. The risk factor to develop a pressure sore brought us a value of relative risk of 13.42 (IC 95%: 3.31-54.3) in the group wearing the protective bandage compared to the group wearing the dressing. COMMENTS: The results of this study allow us to accept as valid the alternate hypothesis that there exist significant statistical differences between both treatment methods in favor of the Allevyn Heel dressing instead of the protective heel bandage. The use of this dressing, even though it is more expensive a priori than the protective bandage, in terms of unit cost for the product, has proven to be more effective in preventing pressure sores, and cheaper than the protective bandage if we bear in mind these combination of variables: time of usage, application and removal.

Bandages↗

[Progress in the studies on hydrogel burn dressings].

Synthetic burn dressing remains the central theme for burn dressing development. The advantages and disadvantages of current available dressings were reviewed. As one of the most successful dressings, the hydrogel burn dressing, its combination with other materials and related progress in researches were presented in detail. Finally, the trend in development of synthetic burn dressing was presented.

Bandages, Hydrocolloid↗

[Hygienic and physiological aspects of changing dressings].

The dressing has an impact on wound healing. If we want to prevent impaired wound healing, exchange of dressings must be done with hygienic precautions and damage of the wound must be avoided. It is better to use for re-dressing single-use sterile dressings from the so-called set-system than dressings from sterile drums. Selection of dressings should depend on the stage of healing of the wound. If a major wound is uncovered and left so for a long time, this interferes with healing.

Bandages↗

[Hemostatic effects of Sorbalgon dressing after intranasal endoscopic surgery].

OBJECTIVE: To study the therapeutic effects of Sorbalgon dressing for hemostasis after intranasal endoscopic surgery. METHODS: Intranasal endoscopic surgery was performed in 50 patients with bilateral chronic nasosinusitis and nasal polyps, after which the hemostatic effect of Sorbalgon and Vaseline dressings and nasal cavity reaction were observed. RESULTS: Sorbalgon dressing resulted in milder nasal swelling and pain without obvious nasal hemorrhage and mucous membrane reaction, and the average time of nasal recovery was shorter in comparison with Vaseline dressing, which caused severe pain, obvious haemorrhage, and nasal mucous membrane swelling with prolonged nasal recovery. Three months after the operation, similar mucous membrane epithelialization was observed in the nasal cavity managed with the two dressings. CONCLUSION: Sorbalgon dressing has good hemostatic effect after intranasal endoscopic surgery.

Adult↗

Evaluation of a lipidocolloid wound dressing in the local management of leg ulcers.

OBJECTIVE: To evaluate the efficacy, tolerance and acceptability of Urgotul and DuoDERM E dressings in the local management of venous or mixed-aetiology leg ulcers. METHOD: This was a prospective multicentre randomised phase IV clinical trial conducted open-label in parallel groups. It involved 20 investigating centres, including hospital dermatology and vascular medicine departments, and private practices. Dermatologists and angiologists/phlebologists took part. Subjects were adult, non-immunosuppressed patients presenting with a non-infected, non-malignant leg ulcer of predominantly venous origin (ABPI > 0.8). Ulcers were between 4cm2 and 40cm2 in size, with granulation tissue covering more than 50% of their surface area. Ulcer duration ranged from three to 18 months. Patients were followed-up by the investigating physician for eight weeks on a weekly basis; this included clinical examination, wound area tracings and photographs. Nurses (hospital or visiting) assessed exudate volume and clinical appearance at dressing changes. RESULTS: Ninety-one patients were included: 47 in the Urgotul group and 44 in the DuoDERM E group. Baseline patient demographic data and wound characteristics were comparable in the two groups. After eight weeks of treatment wound surface area had reduced by a mean of 61.3% in the Urgotul group and 52.1% in the DuoDERM E group (NS); dressings were changed more frequently in the DuoDERM E group (2.54 +/- 0.57 times per week versus 2.31 +/- 0.45 in the Urgotul group, p = 0.047). Thirty-three local adverse events were recorded in 27 patients: 10 in the Urgotul group and 23 in the DuoDERM E group (p = 0.039). Nurses reported better acceptability for the Urgotul dressing, based on pain on removal, maceration and odour (p < 0.0001). CONCLUSION: Both dressings showed similar efficacy for the local treatment of venous leg ulcers. Nevertheless, medical and nursing staff reported better tolerance and acceptability for the Urgotul dressing.

Adult↗

[Therapeutic behavior of a hydrocolloid dressing. Its evolution in the treatment of acute and chronic dermal ulcers].

OBJECTIVE: Evaluate the behavior of a Sureskin II hydrocolloid dressing in the treatment of acute and chronic dermal ulcers in daily clinical practice. METHODS: By means of an observational, multi-centric, prospective, open study of a series of clinical cases on patients afflicted by acute and chronic ulcers. This study lasted through 20 dressing changes or until the ulcer was cured. During the initial visit, the characteristics of the lesion were evaluated; in continuation, the evolution of a lesion as dressings were changed was evaluated; and during the final visit, the professional team evaluated the final traits of the lesion along with the overall behavior of the dressing applied. RESULTS: This study evaluated 1080 patients whose average age was 72.3 years. At the conclusion of this study the investigators noticed that the size of these ulcers had significantly reduced from the start to the end of treatment. Epithelization increased from 43.2 to 71.9%. 98.3% of patients in this study considered this dressing brand easy to apply Seepage of exudation diminished from 31.77 to 14.6%. The presence of maceration, erythema and eczema also reduced from 29.2 to 12.5%, from 37.6 to 13.1% and from 9.7 to 6.3% respectively. The symptoms of infection or inflammation dropped from 22.6 to 7.6%. Patients' complaints of pain when their dressings were changed dropped 29.4%. 90.7% of these patients stated this treatment alleviated their symptoms and allowed them to carry on their daily activities in a normal fashion. CONCLUSION: The results of this study show that the use of Sureskin II is effective, therefore making it a first choice therapeutic option for treating patients suffering from acute and chronic dermal ulcers.

Acute Disease↗

Silver deposition and tissue staining associated with wound dressings containing silver.

Argyria is the general term used to denote a clinical condition in which excessive administration and deposition of silver causes a permanent irreversible gray-blue discoloration of the skin or mucous membranes. The amount of discoloration usually depends on the route of silver delivery (ie, oral or topical administration) along with the body's ability to absorb and excrete the administered silver compound. Argyria is accepted as a rare dermatosis but once silver particles are deposited, they remain immobile and may accumulate during the aging process. Topical application of silver salts (eg, silver nitrate solution) may lead to transient skin staining. To investigate their potential to cause skin staining, two silver-containing dressings (Hydrofiber and nanocrystalline) were applied to human skin samples taken from electively amputated lower limbs. The potential for skin discoloration was assayed using atomic absorption spectroscopy. When the dressings were hydrated with water, a significantly higher amount of silver was released from the nanocrystalline dressing compared to the Hydrofiber dressing (P <0.005), which resulted in approximately 30 times more silver deposition. In contrast, when saline was used as the hydration medium, the release rates were low for both dressings and not significantly different (silver deposition was minimal). Controlling the amount of silver released from silver-containing dressings should help reduce excessive deposition of silver into wound tissue and minimize skin staining.

Administration, Cutaneous↗

[Effect of silver nanoparticle dressing on second degree burn wound].

OBJECTIVE: To explore the influence of silver nanoparticle dressing on prevention of infection and healing of the second degree burn wound. METHODS: One hundred and ninety-one burn patients with second degree including superficial and deep burn wound were randomly divided into three groups. Group A including 65 cases was treated by silver nanoparticle dressing on wounds, and group B (63 cases) and group C (63 cases) were treated by 1% silver sulfadiazine cream and vaseline gauze on their wounds, respectively. Dressing was changed daily, and wound swab bacterial cultures were performed before and after dressing change, and also wound healing times were recorded in each patient. RESULTS: Group A and B were similar in their bacterium colonizations on wound after treatment with the silver nanoparticle dressing and 1% silver sulfadiazine cream, and they had a similar effect on reducing bacterium colonization on wound after treatment, while in vaseline gauze group bacterium colonization on wound increased after treatment. In group A the wound healing time of superficial second degree was significantly shorter than those in group B and group C (P < 0.01). In deep second degree wounds the healing time in group A was much shorter than that in group C (P < 0.01), but had no significant difference when compared with group B (P > 0.05). CONCLUSION: Silver nanoparticle dressing can be used on second degree burn wound and can decrease the risk of wound infection and accelerate wound healing.

Adult↗

[Application of carbon fiber dressing on burn wounds].

OBJECTIVE: To observe the effects of carbon fiber dressing on burn wounds. METHODS: Two hundreds and seventy seven burn patients were randomly divided into treatment group (group T) and control group (group C). The burn wounds were covered with carbon fiber dressing in T group, and with povidone iodine gauze in C group, respectively. The absorption capability of the dressing, inflammatory reaction and bacteria quantitation of wound tissues and wound healing time were observed, and biopsy of wounds were performed. RESULTS: The absorption capability of the dressing was higher, the wound inflammatory reaction was milder, and bacteria quantitation of wound tissues was lower in the group T than that in group C. The wound healing time in the group T was shorter than that in group C. CONCLUSIONS: Carbon fiber dressing is a new model dressing, it can absorb wound exudation, lessen inflammatory reaction and improve wound healing.

Adolescent↗

Biofilm hydrogel dressing: a clinical evaluation in the treatment of pressure sores.

A new dressing for chronic wounds, BioFilm hydrogel dressing, was compared to a hydrocolloid dressing (HCD) control in a clinical trial involving 90 patients and 129 Stage I and II wounds (defined by Enis and Sarmienti). The testing sites included both acute care and extended care facilities. A comparison of healing response and functional characteristics of both dressings was part of this assessment. Biofilm dressings demonstrated a healing advantage over the HCD. In addition, clinicians judged that the hydrogel dressings were easier to use and had superior fluid management capability and product integrity with minimal disruption to the healing wounds.

Adult↗

Calcium alginate topical wound dressings: a new dimension in the cost-effective treatment for exudating dermal wounds and pressure sores.

Sorbsan Topical Wound Dressing maintains a physiologically moist microenvironment that promotes healing and the formation of granulation tissue. In addition, Sorbsan is extremely absorbent, making it particularly useful for rapid and effective removal of exudate. Since Sorbsan can be rinsed away with saline irrigation, removal of the dressing does not interfere with healing granulation tissue, a factor that makes dressing changes virtually painless. Sorbsan also provides a physical barrier against inadvertent contamination of the wound. No adverse reactions to the dressing have been reported in any of the studies published to date. Sorbsan is also cost-effective because the frequency of dressing change is significantly reduced. These qualities add up to an ideal, easy to use dressing for moderate to heavily exudating wounds.

Alginates↗

Care of pressure sores: a controlled study of the use of a hydrocolloid dressing compared with wet saline gauze compresses.

An occlusive hydrocolloid dressing (Comfeel Ulcus) was compared with a conventional wet saline gauze dressing regarding the effect on ulcer cleansing and healing processes, experience of pain and the consumption of nursing time, in a controlled, randomized and partially single-blind study with parallel groups of long-stay patients with pressure sores. After a few weeks' treatment the relative decrease in ulcer areas with time was larger in the group treated with the hydrocolloid dressing. The difference was almost statistically significant at week 5 (p = 0.054) and definite at week 6 (p = 0.006). At week 6 the median remaining ulcer area in per cent of the initial area was 0% in the hydrocolloid dressing group and 31% in the group treated with saline gauze (p = 0.016). Analysis of the healing distribution function showed the hydrocolloid dressing to be more effective, although the overall difference was non-significant (p = 0.15). Care of the pressure sore took significantly less time with hydrocolloid dressings.

Aged↗

[Moist wound treatment with ointment dressings in surface skin defects].

The advantages of moist wound treatment by means of ointment gauze dressing are based on the following attributes of the marked tulle gras preparations: --easy to handle; storage without problem --the gauze dressings can be modeled easily even on difficult body contoures (for example in the face) --the gauze dressing can be changed easily --Synthetic tulle gras dressings do not fray so that no residues remain in the wound. Therefore the danger of adhesion with the wound can be minimized. --There is no congestion of secretions undermath the gauze dressing. --undisturbed healing: a presupposing factor for optimal cosmetic and therapeutic result. --Minimal danger of contact dermatitis by using paraffin gauze dressing without antiseptic additives.

Bandages↗

Detachable cast pylon technique for rigid dressings on below-knee amputee patients.

The attachment of a pylon and prosthetic foot to a postoperative rigid dressing can be beneficial in the management of a below-the-knee amputation. Recently, a rigid, removable dressing has been used to allow easy inspection of the stump during healing. The removal of the pylon and prosthetic foot at night, preventing unsupervised ambulation, is accomplished by a disconnecting mechanism, which is permanently attached to the end of the rigid removable dressing. This disconnecting mechanism adds to the bulk and weight of the rigid dressing, increasing the shear force on the stump. We are introducing the detachable cast pylon technique, in which a fabricated sleeve attached to the pylon is easily and completely attached and detached from a rigid dressing. It is lightweight, less bulky, easily fabricated, and inexpensive. It offers a quick disconnect system for either the Otto-Bock attachment plate or uniquely with PVC tubing. In addition, this technique affords consistency in shaping the stump, as the same rigid dressing can be used for both rest and training. Its intent is for in-hospital use or when ambulation is restricted to supervised situations.

Acetaminophen↗

[Non-comparative evaluation of a new hydrofiber dressing in the treatment of vascular ulcers].

OBJECTIVE: To evaluate the performance of the hydrofiber dressing in the treatment of leg ulcers. METHODS: Multicenter, open, non-comparative study of 23 patients with the mean age of 69.6 years. The mean duration of actual ulcer was 2.6 years. RESULTS: Twelve (55%) patients had marketed improvement in overall change in the condition on the wound and 5 (23%) patients had mild improvement. The majority of dressing changes were pain-free (63%). The dressing changes, application and removal, were easy 171 (99%) and 149 (87%). The mean dressing wear time was 2.4 days. The mean ulcer area at the start of the study was 2.730 mm2 and the final dressing change was 1.963 mm2. The median percentage reduction was 36%. CONCLUSION: The use of the non-occlusive hydrofiber dressing is suitable for the treatment of exudating leg ulcers.

Aged↗

A fibre-free alginate dressing in the treatment of split thickness skin graft donor sites.

BACKGROUND: Alginate dressings are gaining acceptance in would management although comparative published data with conventional treatment is inconclusive. AIMS: The aim of this randomised controlled study was to compare a fibre-free alginate dressing (Comfeel SeaSorb) with conventional treatment of standardised split-thickness skin graft donor sites in 17 patients regarding initial absorption of blood and healing. RESULTS: The alginate dressing absorbed 40% (P < 0.05) more blood, measured as total iron content of used dressings, during the first 10 post-wounding minutes than fine mesh gauze, resulting in less subsequent bleeding. Light microscopic examination of punch biopsies obtained from 10 wounds on post-operative day 6 demonstrated that nine wounds treated with the alginate dressing compared with seven wounds treated conventionally with paraffin-impregnated gauze (Jelonet) were completely epithelialized, a statistically non-significant difference (P = 0.46). CONCLUSIONS: In conclusion, the fibre-free alginate dressing showed increased initial blood absorption resulting in quicker haemostasis but showed no greater beneficial effect on epithelialisation of split-thickness skin graft donor sites compared with conventional topical treatment.

Absorption↗