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At least 469 records · Page 26Linked to original sources
PubMed1985

Recovery of contrast sensitivity following bilateral orbital decompression: a case report.

Contrast sensitivity (CS) was measured in a patient with bilateral optic nerve compression resulting from thyroid ophthalmopathy. Initially both right and left contrast sensitivity functions (CSF's) were markedly attenuated over the spatial frequency range measured. CS improved significantly after surgical decompression although distance visual acuities remained unchanged during most of the period of observation. Sensitivity to medium- and high-spatial frequencies remained attenuated compared to the level achieved by a normal group of subjects of a similar age decade.

Differential Threshold↗
PubMedDate not supplied

[Objective evaluation of contrast sensitivity by visual evoked potentials].

The Contrast Sensitivity Function (CSF) is ore often determined by a psychophysical method. To obtain an objective measurement of CSF, we used steady-state Visual Evoked Potential (VEP) with a real time technique. Contrast levels are higher for thresholds determined by VEP technique. Correlation between psychophysical and objective methods is quite good.

Contrast Sensitivity↗
PubMed2001

Contrast sensitivity following focal laser photocoagulation in clinically significant macular oedema due to diabetic retinopathy.

PURPOSE: To evaluate the influence of focal aser photocoagulation on contrast sensitivity in diabetic patients with clinically significant macular oedema (CSMO). METHODS: A prospective non-comparative interventional study was performed on a group of patients with CSMO at Dr Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi, a tertiary eye care centre. Thirteen diabetc patients (14 eyes) with CSMO and no history of prior photocoagulation were recruited for this study. Direct focal photocoagulation of all leaking microaneurysms was performed using an argon green laser (514 nm). A contact lens was used as a slit lamp delivery system. Evaluation of the best corrected Snellen visual acuity, contrast senstivity, slit lamp biomicroscopy, macular status on direct ophthalmoscopy and fluorescein angiography was carried out 1 month and 3 months after laser photocoagulation. RESULTS: Following direct focal laser photocoagulation, focal CSMO resolved completely in all but one eye, 4-8 weeks later, as seen on slit lamp biomicroscopy and/or fluorescein angiography. Post-treatment, visual acuity remained stationary in eight eyes, improved by one line in three eyes, by two lines in two eyes and by three lines in one eye. The mean +/- SD pretreatment and post-treatment decimal visual acuities were 0.49+/-0.30 and 0.59+/-0.28, respectively. The mean +/- SD pre-laser contrast sensitivity score was 121.3+/-83.6, which increased significantly to a mean +/- SD of 151.6+/-80.5 fo lowing direct focal photocoagulation. CONCLUSION: Focal argon laser photocoagulation in CSMO in diabetics helps in improving the contrast sensitivity and stabilizes the visual acuity. The changes in contrast sensitivity and visual acuity are independent of each other.

Contrast Sensitivity↗
PubMed2002

Effect of artificial tears on corneal surface regularity, contrast sensitivity, and glare disability in dry eyes.

OBJECTIVE: To investigate the effects of artificial tears on corneal surface regularity and visual function in dry eyes. DESIGN: Nonrandomized, comparative trial. PARTICIPANTS: Forty patients (40 eyes) with dry eyes with (group 1, n = 15 eyes) or without (group 2, n = 25 eyes) punctate epithelial keratopathy and a normal control group of 20 individuals (20 eyes) with no ocular abnormalities (group 3). METHODS: In both dry and normal eyes, the surface regularity index (SRI), surface asymmetry index (SAI), and potential visual acuity (PVA) were measured by computer-assisted videokeratography (TMS-1; Computed Anatomy, New York, NY). Spatial-contrast sensitivity and glare disability were also measured before and 1 minute after instillation of artificial tears. MAIN OUTCOME MEASURES: Differences in SRI, SAI, PVA, spatial-contrast sensitivity, and glare disability between groups, before instillation of tears, and within groups, after instillation of tears. RESULTS: Compared with group 3, eyes in group 1 had significantly worse SRI, SAI, PVA, and contrast sensitivity (incomplete glare disability data precluded analysis) before instillation of artificial tears. Differences in corneal surface regularity and visual function between groups 2 and 3 were not significant except for a significantly increased glare disability at low spatial frequency (1.5 cycles per degree [cpd]) in group 2. Significant improvement in SRI, SAI, PVA, and contrast sensitivity were observed after instillation of artificial tears in group 1. In groups 2 and 3, the only significant changes were improvement in glare disability at 1.5 cpd and worsening of the SRI, respectively. CONCLUSIONS: Tear film changes in dry eye patients may lead to irregularities on the corneal surfaces, causing glare disability. However, these changes may be too subtle in the early stages of dry eyes to be detected by corneal topography or contrast sensitivity measurements. Significant improvement in SRI, SAI, PVA, and contrast sensitivity were found after instillation of artificial tears in dry eyes with punctate epithelial keratopathy.

Adult↗
PubMed2002

[Characteristics of visual acuity and contrast sensitivity in students of different ages].

To investigate the peculiarities of the visual acuity and contrastive sensitivity 60 healthy pupils (120 eyes) of different ages (7-16) were examined with a help of the computer diagnostic program "Oculus-W" V95. The increase in both the visual acuity and the contrastive sensitivity with age have been shown, as well as the parametres of their normal levels for different ages have been determined. It makes estimating the functional state of the visual analyzer more exact. The processes of making the visual acuity and the contrast sensitivity in the schoolchildren have been proved to interdependent.

Adolescent↗
PubMed1988

Spatial contrast sensitivity: effects of age, test-retest, and psychophysical method.

Spatial contrast sensitivity was tested twice in normal subjects from five age groups by using each of two different psychophysical methods. Results obtained by the method of adjustment showed a decline in sensitivity with increasing age at all spatial frequencies. In contrast, the forced-choice procedure yielded results indicating an age-related decline predominantly at high spatial frequencies, with the magnitude of the decline being generally similar to that obtained earlier by a tracking method [Vision Res. 23, 689 (1983)]. The decline that we observed cannot be due to pupillary changes with age, since this factor was controlled. Moreover, we suggest that the high-spatial-frequency decline in contrast sensitivity, although it is comparatively small, is too large to be due to changes in lens density. We therefore suggest that a neural component is responsible. In addition, interactions among the age of the subject, the spatial frequency used, and the psychophysical method used suggest that the method of adjustment should be avoided for age-related studies of vision.

Adult↗
PubMed1990

Brightness discrimination and contrast sensitivity in chronic glaucoma--a clinical study.

The visual acuity, the difference in sensitivity of the two eyes to light (brightness ratio), and contrast sensitivity were assessed in 28 patients with chronic open angle glaucoma and compared with those of 41 normal controls of similar ages and visual acuity. The results obtained were related to the results of Tübingen visual field analysis in patients with glaucoma. Twenty-four of the 28 glaucoma patients (86%) had a significant disparity in brightness ratio between the two eyes. This was found to match the frequency of visual field loss. Moreover, there was a significant relationship between the interocular differences in brightness sense and the difference in the degree of visual field loss between the two eyes. Of the glaucoma patients 39% had sum contrast sensitivities outside the normal range for age-matched normal controls. No significant correlation was found between the interocular difference in brightness sense and the visual acuity or the interocular difference in sum contrast sensitivity. It is concluded that, in the presence of a normal visual acuity, the brightness ratio test warrants evaluation as a potential screening test for chronic open angle glaucoma.

Adult↗
PubMed1988

Effect of stimulus orientation on contrast sensitivity in Parkinson's disease.

We studied the effect of stimulus orientation on contrast sensitivity function in 21 patients with Parkinson's disease and in 10 normal subjects. This was done by measuring contrast sensitivity over a range of spatial frequencies for vertical and horizontal sine wave grating stimuli. There was a great test-retest consistency in normal subjects and patients. Fifteen of the 21 patients showed contrast sensitivity deficit in at least one eye. Orientation-specific loss was demonstrated in 17 of the 25 "affected" eyes. The most frequent type of orientation-specific loss was a notch defect, which preferentially affected the middle spatial frequencies. We attribute orientation-specific and spatial frequency-selective loss in Parkinson's disease to a functional disruption of neurons on the visual cortex.

Aged↗
PubMed1989

Sawtooth contrast sensitivity: decrements have the edge.

Mirror-image sawtooth waveforms (rapid-on and rapid-off) were used to test for differences in sensitivity to incremental and decremental stimuli. Temporal contrast sensitivity functions were measured for rapid-on and rapid-off sawtooths and for sine wave stimuli (for 2-26 Hz, mean retinal illuminance of 500 td, circular target of 1.8 deg, foveal). Rapid-off sawtooths yielded higher sensitivity than rapid-on sawtooths at low and middle frequencies. This advantage for detection of decremental lights was confirmed in an experiment in which contrast sensitivity was determined for the sum of a rapid-on and a rapid-off waveform added over the full range of phase angles. Our data, based on periodic rather than pulsed stimuli, broaden and strengthen the evidence that the visual system is more sensitive to decrements than to increments in light level.

Contrast Sensitivity↗
PubMed1992

Contrast sensitivity and reading through multifocal intraocular lenses.

Multifocal intraocular lenses are intended to increase depth of focus for patients with cataracts, but optical considerations predict reduced retinal-image contrast. We evaluated visual performance through multifocal intraocular lenses by measuring contrast sensitivity functions and reading speed for age-matched groups with multifocal and monofocal intraocular lenses and two normal control groups. Contrast sensitivity functions of the patients with multifocal lenses did not differ significantly for optical distances differing by 2.5 diopters, indicating substantial depth of focus. Normal and monofocal contrast sensitivity functions were nearly identical, and both were about a factor of two higher than multifocal contrast sensitivity functions. Patients with multifocal lenses showed deficits in reading speed only for low-contrast text (less than 30%) and small letters (0.2 degree and 1.0 degree).

Aging↗
PubMed2006

Abnormal neurological signs, visual contrast sensitivity, and the deficit syndrome of schizophrenia.

This study was designed to investigate the relationship between abnormal neurological signs, visual contrast sensitivity, and the deficit syndrome of schizophrenia. Visual contrast sensitivity for counterphase-modulated low spatial frequency gratings was measured in 32 non-deficit and 12 deficit schizophrenia patients and 20 healthy controls subjects. Abnormal neurological signs were evaluated with the Neurological Evaluation Scale (NES). Compared with the controls, patients with schizophrenia displayed impaired visual contrast sensitivity, which was associated with sensory integration deficits, as measured with the NES. The deficit syndrome was predicted by negative symptoms and sensory integration deficits. These results suggest that early-stage perceptual dysfunctions, which may reflect the abnormality of precortical magnocellular visual pathways, are related to a specific group of abnormal neurological signs.

Adult↗
PubMed1995

Test-retest variability and correlations between tests of texture processing, motion processing, visual acuity, and contrast sensitivity.

PURPOSE: To compare the test-retest variability (reliability) and the relations among clinical tests of texture and motion processing, visual acuity for high- and low-contrast letters, and the Pelli-Robson contrast sensitivity test. METHODS: In 20 normally sighted subjects, monocular visual acuity for letters of 96% and 11% contrast, Pelli-Robson contrast sensitivity, and motion-defined and texture-defined letter recognition thresholds were measured on each of two different days. RESULTS: Test-retest correlation coefficients were 0.75, 0.91, 0.61, 0.90, and 0.84 and bivariate test-retest regression slopes were 1.0, 1.1, 0.8, 1.0, and 1.2 for high- and low-contrast acuity, contrast sensitivity, and motion and texture processing, respectively. The inter-test correlations with both test and retest significant were as follows: visual acuity for high-contrast letters vs. visual acuity for low-contrast letters; and recognition threshold for texture-defined letters vs. acuity for letters of both high and low contrast. CONCLUSION: Test-retest variability for the tests of motion and texture processing were at least as low as for established clinical tests of high and low contrast acuity and contrast sensitivity. We conclude that these new tests offer a reliable means of obtaining clinical information which complements that provided by conventional tests with luminance-defined letters.

Adolescent↗
PubMed1992

Computerized Arden grating technique for the measurement of the contrast sensitivity function.

We developed a computerized contrast sensitivity function (CSF) measurement technique using a computer graphics board to reproduce Arden grating type stimuli. The reliability of the procedure was examined by evaluating the standard deviation of repeated test differences. The validity of the procedure was tested by comparison with both a manual method of adjustment technique and with Regan low contrast letter charts. The procedure has been performed at a number of exposure speeds to account for the effect of reaction time and attention of the results. The optimum exposure time for the procedure has been found to be greater than or equal to 22 s. As a result of the benefits of automation the test is quick, produces test-retest correlation coefficients for the five spatial frequencies tested which are similar to those for the method of adjustment procedure (0.76 to 0.91 for the computerized test, 0.66 to 0.88 for the signal generator measurements), and produces values which correspond closely with the method of adjustment measurement. It has the advantages of utilizing hardware already available in many computer systems, having a constant mean luminance across the screen, and having a constant and optimized presentation time.

Adult↗
PubMed1995

Comparison of visual evoked potential and psychophysical contrast sensitivity.

We measured contrast processing as a function of spatial and temporal frequency using three measurement techniques: psychophysical thresholds, visual evoked potential (VEP) thresholds and VEP amplitudes. Measurements were made using the same stimulus parameters and on the same group of subjects. The agreement among these functions depended upon the particular spatio-temporal stimulus employed and in general, there were more differences than similarities among these measures. For example, VEP derived functions (both amplitude and threshold) peaked at 4 c/deg, whereas, the psychophysical functions peaked at 1 c/deg. VEP amplitude functions were maximum at > or = 3.5 Hz, whereas both psychophysical and VEP sensitivity were maximum at < or = 2.5 Hz. VEP thresholds were broad and low pass in shape and in contrast, the psychophysical and VEP amplitude functions were band pass. In summary, comparisons among these measures of contrast processing must be made with caution.

Adult↗
PubMed2005

Contrast sensitivity for letter optotypes vs. gratings under conditions biased toward parvocellular and magnocellular pathways.

This study examined the extent to which letter optotypes and grating stimuli provide equivalent measures of contrast sensitivity under conditions designed to favor the magnocellular (MC) and parvocellular (PC) pathways. The contrast sensitivity functions (CSFs) of three visually normal observers were measured for Sloan letters and Gabor patches, using steady- and pulsed-pedestal paradigms to bias processing toward MC and PC pathways, respectively. CSFs for Gabor patches were low-pass for the steady-pedestal paradigm and band-pass for the pulsed-pedestal paradigm, in agreement with previous reports. However, CSFs for letters were low-pass for both testing paradigms. CSFs for letters restricted in frequency content by spatial filtering were equivalent to those for Gabor patches for both testing paradigms. Results indicate that conventional letter optotypes can provide a misleading measure of contrast sensitivity, especially under conditions emphasizing the PC pathway. The use of spatially band-pass filtered letters can provide a more appropriate evaluation of spatial contrast sensitivity while maintaining some of the potential advantages of letters.

Adult↗
PubMed2002

Multifocal glasses impair edge-contrast sensitivity and depth perception and increase the risk of falls in older people.

OBJECTIVES: To determine the extent to which multifocal glasses impair contrast sensitivity and depth perception at critical distances required for detecting hazards in the environment and whether multifocal glasses use increases the risk of falls in older people. DESIGN: One-year prospective cohort study. SETTING: Falls Laboratory, Prince of Wales Medical Research Institute. PARTICIPANTS: One hundred fifty-six community-dwelling people aged 63-90. MEASUREMENTS: Contrast sensitivity, depth perception, accidental falls. RESULTS: Eighty-seven subjects (55.8%) were regular wearers of multifocal (bifocal, trifocal, or progressive lens) glasses. These subjects performed significantly worse in the distant depth perception and distant edge-contrast sensitivity tests in conditions that forced them to view test stimuli through the lower segments of their glasses. Multifocal glasses wearers were more than twice as likely to fall in the follow-up period than nonmultifocal glasses wearers (odds ratio (OR) = 2.29, 95% confidence interval (CI) = 1.06-4.92), when adjusting for age, poor vision, reduced lower limb sensation and strength, slow reaction time, and increased postural sway. Multifocal glasses wearers were also more likely to fall because of a trip (OR = 2.79, 95% CI = 1.08-7.22), when outside their homes (OR = 2.55, 95% CI = 1.14-5.70), and when walking up or down stairs (P <.01). The population attributable risks of regular multifocal glasses use were 35.2% for any falls, 40.9% for falls due to a trip, and 40.9% for falls outside the home. CONCLUSIONS: The study findings indicate that multifocal glasses impair depth perception and edge-contrast sensitivity at critical distances for detecting obstacles in the environment. Older people may benefit from wearing nonmultifocal glasses when negotiating stairs and in unfamiliar settings outside the home.

Accidental Falls↗
PubMed1997

Contrast sensitivity with silicone and poly(methyl methacrylate) intraocular lenses.

PURPOSE: To compare the optical performance of silicone intraocular lenses (IOLs) with that of conventional poly(methyl methacrylate) (PMMA) IOLs. SETTING: University hospital outpatient cataract clinic. METHODS: Ninety-one patients were randomly assigned to receive a PMMA IOL (n = 48 eyes) or a silicone IOL (n = 43 eyes). Contrast sensitivity was evaluated 4 months after surgery using the Vistech sinusoidal-grating chart and the Pelli-Robson letter sensitivity chart. RESULTS: No between-group differences were found using the Vistech test. Using the Pelli-Robson test, mean uncorrected contrast sensitivity was 1.59 log units +/- 0.13 (SD) in the PMMA group and 1.53 +/- 0.15 log units in the silicone group. Mean best corrected contrast sensitivity was 1.67 +/- 0.11 and 1.63 +/- 0.16, respectively. The differences between groups using the Pelli-Robson test were statistically significant (P < .05). No correlation was found between reduced contrast sensitivity and brownish discoloration or thickness of silicone IOLs or posterior capsule fibrosis. CONCLUSION: Contrast sensitivity was lower in patients with silicone IOLs than in those with conventional PMMA lenses.

Adult↗