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[Conization and pregnancy--an analysis of various therapeutic measures for the prevention of premature labor].

In the period under review from 1/6/1980 to 31/3/1990 119 women with a state after conisation of the cervix have been delivered. For treatment of a resultant cervical incompetence there were used in 46% a cervical cerclage, in 7% a support pessary, in 20% the combination of cerclage: pessary and in 27% conservative measures. Retrospectively the final gestational week, the proportion prematured rupture of membranes, of prematurity and dates of the fetal outcome have been examined. The results demonstrate that a selection of patients has to be made with state after conisation according to the seriousness of the cervical incompetence giving the adequate indication for a conservative or active (cerclage and/or pessary) treatment referrend to pregnancy length and the uterine cervix findings. A general determination of only one treatment method for prophylaxis of therapy with state after cervix conisation is not advisable, be cause the results of all examined patient groups--after selection--were not significantly different.

Adult↗

[Pregnancy outcome after conization].

The outcome of pregnancy in 68 women with previously made conisation of the uterine cervix is presented. As a control group were 68 pregnancies which were the first in the protocol following the examined ones. Of 68 women of observed group there were 45 (66.2%) term deliveries, 10 (14.7%) preterm deliveries, and 13 (19.1%) spontaneous abortions, while in women of control group the results were 52 (76.5%), 6 (8.8%) and 10 (14.7%) respectively. This did not represent a statistical significance (chi 2 = 1.89; p less than 0.05). In the first desired pregnancy after conisation 43 (63.2%) women were resting in bed and taking medicaments, 20 (29.4%) had cervical cerclage, while in women of the control group there were 14 (20.6%) and 5 (7.4%), respective what represents statistically significant difference (chi 2 = 25.4; p less than 0.01; chi 2 = 11.3; df = 1, p less than 0.01). Of 43 women of observed group with resting and medicaments in pregnancy 33 (76.7%) had term deliveries, 8 (18.6%) preterm deliveries and 2 (4.7%) spontaneous abortions, while in 25 women without resting and no medicaments, the results were 13 (52%), 11 (44%), 1 (4%) respectively. This represents statistical significant difference (chi 2 = 4.42; p less than 0.05). In the control group of 54 women without resting and no medicaments, there were 45 (83.3%) term deliveries, 3 (5.6%) preterm deliveries and 6 (11.1%) spontaneous abortions, while in 25 women after conisation and no resting there were 13 (52%), 11 (44%), 1 (4%) respectively. This represents a statistical significance (chi 2 = 8.59; p less than 0.01). (ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[From Wertheim's radical abdominal hysterectomy to conization].

In surgical treatment of cancer of the uterine cervix, we were convinced for a long time that it is only by increasing the radicality that we can improve the result of the treatment. But it was only by massive application of some newer methods of detection of various forms of the uterine cervix that we changed that view. Largest changes, however, and different views as well, become evident in deciding on the methods of surgical treatment of the I A stadium. Concurrently with a demonstration of that process, illustrated by the experiences of 2603 Wertheim operations, performed at the Gyneacologic Clinic in Ljubljana, some unknown or wrongly shown historical facts of the surgical treatment of cancer of the uterine cervix are presented.

Female↗

[Experience with 1000 cases of conization of the uterine cervix].

Authors made a follow-up study of 1000 portio conisations. They analysed the early and late postoperative complications with special regard to the further obstetrical outcome. They valued the previous cytologic and colposcopic examinations on the basis of histologic diagnosis. It has been found that complications were neither frequent nor serious and had no unfavourable influence on further pregnancies. They found a higher ratio both of false positive and negative cytologic and colposcopic results then it is given by the literature. Authors come to the conclusion, that even in cases of anatomical portio alterations it's necessary the detailed histologic examinations, that for the portio conisation is a preferable method.

Cervix Uteri↗

[Laser conization in the treatment of early forms of cervical cancer].

High laser excision has been used as an organ-sparing method for early cervical cancer in 30 patients, admitted to the P. A. Herzen Gynecological Clinic. Mean age of the patients was 35.7 +/- 1.5 years. The stage of the disease corresponded to intraepithelial cancer in 15 patients, and to micro-invasive cancer in another 15. The patients were followed-up for 6 months to 2 years, there were no relapses or menstrual disorders. Complications included early postoperative bleedings in 4 patients (the operation was performed in the premenstrual days).

Adult↗

[Cervical conization in the diagnosis and treatment of cervical epithelial neoplasms].

Thirty-seven patients who underwent cone biopsy for cervical intraepithelial neoplasia (CIN) of varying gravity have been considered. The follow-up points to the therapeutic as well as diagnostic value of this intervention (92% success). Analysis of the responses provided by colpocytology in comparison with those provided by biopsy, evidences the poor diagnostic reliability of the pap-test with respect to intraepithelial lesions of the uterine cervix (under-estimated in 51% of cases compared to biopsy). Operation did not substantially modify patients' reproductive capability (5 pregnancies of which 3 developing, during the control period) an extremely important factor in view of the young age of patients (average 31 years).

Adult↗

[Electro-conization of the cervix uteri].

After having reported various opposite techniques for the treatment of dysplasia and in situ carcinomas of the uterine cervix, the authors present their experience with 125 cases of conisation, performed between 1984 and 1988. The electroconisation technique, performed in 88 cases, is compared with other conisation techniques: conisation with a cold scalpel, laser conisation. The use of a cold scalpel is simple and effective, but presents the disadvantage of peroperative (22.2% in our series) and secondary (7.4%) haemorrhages requiring preventive overlapping stitches which impede subsequent monitoring. Laser conisation seems long and tedious. On the contrary, electroconisation presents the advantage of being simple and quick, with very few peroperative (6.8%) or secondary (3.4%) haemorrhages, but two minor drawbacks: impeding pathological interpretations (1%), causing secondary stenoses which seem to be related to the height of the cone and not to the type of conisation.

Adult↗