Lecithin depletion in liver mitochondria of rats fed a choline-deficient diet. Effect on beta-hydroxybutyrate dehydrogenase.
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Animals↗
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Further studies on choline deficiency and muscular dystrophy in rabbits.
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Animals↗
Tissue levels of acetyl choline and acetylcholinesterase in weanling rats subjected to acute choline deficiency.
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Acetylcholine↗
Effects of long-term alcohol administration on the development of fatty cirrhosis in choline-deficient rats.
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Alcoholic Intoxication↗
Influence of choline deficiency upon the hyperlipemia of alloxan-diabetic rats.
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Animals↗
[Mitochondrial and hepatocyte fat variations in early choline deficiency of the rat. Electron microscopy and quantitative histochemistry].
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Animals↗
Sequential renal changes in choline deficient weanling rats. Conventional and electron histochemistry.
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Acid Phosphatase↗
Pathogenesis of the renal injury in choline deficiency: the role of catecholamines and acetylcholine.
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Acetylcholine↗
Lipoperoxidation in the pathogenesis of renal necrosis in choline-deficient rats.
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Aldehydes↗
Labelling of liver and plasma lecithins after injection of 1-2-14C-2-demethylaminoethanol and 14C-L-methionine-methyl to choline deficient rats.
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Amino Acids↗
Hepatic ATP and triglyceride levels in choline-deficient rats with and without dietary orotic acid supplementation.
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Adenine↗
Renal function in the choline deficient rat.
Abnormalties in renal concentrating ability and free water reabsorption, and a diminished sodium excretion, glomerular filtration rate, and effective renal plasma flow were observed in adolescent rats which ingested a lipotrope deficient diet for 10 months.
Animals↗
Protein metabolism in the choline-deficient rat. II. Effects of age and sex on serum proteins.
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Animals↗
Pathogenesis of the cirrhosis produced by choline deficiency; escape of lipid from fatty hepatic cysts into the biliary and vascular systems.
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Choline Deficiency↗
Reticuloendothelial activity in choline-deficient or carbon tetrachloride-treated rats.
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Animals↗
Choline-deficiency fatty liver: relation of plasma phospholipids to liver triglycerides.
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Animals↗
Modification of the choline deficiency syndrome in the rat by somatotrophin and hydrocortisone.
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Adrenal Cortex↗
Effects of dietary choline deficiency on the mutagenic activation of chemical carcinogens by rat liver fractions.
Salmonella mutagenesis assays were used to evaluate the mutagenicity of several chemical carcinogens as mediated by liver S-9 fractions from rats fed a choline-supplemented (CS) or choline-devoid (CD) diet. The liver S-9 fraction from CD diet-fed rats was found to have a significantly decreased ability to activate 2-acetylaminofluorene (2-AAF), 2-aminoanthracene (2-AA) and 6-aminochrysene (6-AC), but not N-hydroxy-2-acetylaminofluorene (HO-N-2-AAF) and dimethylnitrosamine (DMN). The same liver S-9 fraction was also less effective in deactivating N-methyl-N1-nitro-N-nitrosoguanidine (MNNG) but not methylnitrosourea (MNU). A decrease (20%) in the cytochrome P-450 content was found in liver microsomes of CD diet-fed rats. Although it has been shown that feeding a CD diet to rats enhances chemical hepatocarcinogenesis, the data presented here suggest that CD diet does not increase the activation of the chemical procarcinogens tested.
Animals↗