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At least 469 records · Page 26Linked to original sources
PubMed1989

Interovarian relationship in the secretion of progesterone during the luteal phase of the capuchin monkey (Cebus apella).

In basal conditions, progesterone concentrations were similar in the ovarian veins of the ovary +CL (3211 +/- 526 ng/ml) and the ovary -CL (3165 +/- 554 ng/ml), but after blocking the blood flow between the ovary +CL and the uterus, the progesterone values in the vein draining the ovary -CL decreased to 1218 +/- 394 ng/ml (P less than 0.01). When [3H]progesterone was injected in the ovary +CL, the radioactivity appeared earlier and more concentrated in the vein draining the ovary -CL (30 sec, 0.53% of injected dose) than in the femoral vein (150 sec, 0.08% of injected dose). Removal of the ovary +CL was followed by a brief maintenance of peripheral progesterone within luteal-phase levels. The in-vitro progesterone production by a suspension of cells isolated from the corpus luteum was 47.5 +/- 12.8 ng/ml/2 h, whereas luteal-like cells isolated from the ovary -CL secreted 14.3 +/- 6.0 ng/ml/2 h (P less than 0.01) into the medium. We therefore suggest that the symmetrical and high secretion rate of progesterone by the ovaries of the capuchin monkey indicates a between-ovary communication system, and that the luteal-like tissue of the ovary -CL can produce relatively large amounts of progesterone.

Animals↗
PubMed1981

Note on delay-interval illumination effects on retention in monkeys (Cebus apella).

Two monkeys experienced with delayed matching to sample were given a 30-day baseline training period during which the delay interval was illuminated. Both subjects showed an increase in matching accuracy when shifted to dark delay intervals, and accuracy declined when the illuminated delay interval was reinstituted. These results, as well as earlier reports of facilitation of delayed matching behavior by dark delay intervals, support the view that the absolute level of delay-interval illumination can importantly affect visual retention in monkeys and may be indicative of significant differences in the retention mechanisms employed by monkeys and birds.

Animals↗
PubMed1999

Pharmacokinetics of orally administered desferrithiocin analogs in cebus apella primates.

The pharmacokinetic behavior of three iron chelators based on the desferrithiocin (DFT) pharmacophore, (S)-4, 5-dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid (desmethyldesferrithiocin, DMDFT, 2); (S)-4,5-dihydro-2-(2, 4-dihydroxyphenyl)-4-thiazolecarboxylic acid [4-(S)-hydroxydesazaDMDFT, 3); and (R)-2-(2-hydroxyphenyl)-4-oxazolinecarboxylic acid, the oxazoline analog of desazaDMDFT, 4, is described. Although 2 and 3 are comparably effective in inducing iron excretion upon oral administration, they exhibit markedly different plasma pharmacokinetics. Ligand 2 achieves a substantially higher plasma concentration than does 3, yet the renal clearance of these compounds is similar. The oxazoline analog 4 shows poor iron clearance when administered orally, although it remains in the plasma for extended periods. Chelator 4 demonstrates a marked capacity to bind to human serum albumin compared with the thiazoline derivatives. The possible implications for designing ligands for the treatment of transfusional iron overload are discussed.

Administration, Oral↗
PubMedDate not supplied

White-faced monkey (Cebus capucinus) ecology and management in neotropical agricultural landscapes during the dry season.

Habitat use by a C. capucinus troop was studied in an agricultural landscape during late dry season (March-April 1994) in northwest Costa Rica. Riparian forests, palm canals and living fence rows accounted for 82% of observations, significantly more than the other six habitats present. The study troop consumed 24 species of plants and five animals. Feeding concentrated on the introduced African oil palm (Elaeis guineensis) (33.6%) and mango (Mangifera indica) (27.2%), found mostly in palm canals and mango orchards respectively. The troop rested between 0930-1330 hr and fed and moved between 0530-0930 hr and 1330-1730 hr. Living fence rows were used as travel routes or corridors and less intensively for other activities.

Animals↗