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[The consumption of tranquilizers and "nervous problems" among rural workers].

"Attacks of bad nerves" appeared as a subject for study during an Inquiry into Referred Morbidity in 25 small villages of a rural area of the State of Espirito Santo, Brazil, which have subsisted by virtue of the labor needed for the harmsting of the coffee crops since the beginning of the century. Through the systematic sampling procedure, 93 adults were interviewed about health problems which had occurred in their families during the previous 48 hours and about their attitudes concerning these problems. "Attacks of nerves" or simply "nerves" were reported in the course of 28 (30%) interviews, resulting in 34 reports on the problem, proportionately distributed among settlers and owners of small properties; 14 were men and 20 women; all were rural workers. In 11 (32%) reports, over-work was quoted as the main course of "nerves", either due to its direct effects, or to the affliction related with the coexistence of great efforts to cope with responsibilities, and the small return on all their efforts. In 30 cases (88%) the use of at least one of the 26 psychotropic drugs mentioned was constant (being dauly in 68%). Dependence was explicit by confessed in 47% of them. The reference to "nerves pills" came first or even replaced the description of "attacks of nerves" in 18 (53%) of the interviews, reflecting the strong influence of medical practice and speech on the population.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[Brazil 500 years. A Jesuit anatomical nomenclature at the time of discovery].

The purpose of rendering easier for priests to hear confessions from Brazilian indians, in the beginning of the colonization of Brazil by the Portuguese, and in order to serve indians for better communication led Pero de Castilho, a jesuit born in Vila do Esp¿rito Santo, to prepare a list of names of parts of the human body. Such a list of tupi (language of the native indians) and portuguese terms of anatomical structures, in alphabetical order, seems to be the first Nomina Anatomica published in Brazil. Such a bilingual vocabulary constitutes a subsidy for the study of both languages spoken soon after the discovery of Brazil and represents a religious related document that contributes to the history of anatomy and medicine.

Anatomy↗

The cloning controversy.

Stem cell research has captured the imagination of many, including the scientific and medical community. But the medical community received a wake-up call early this year when a well-known researcher publicly confessed to deception. While the core question relates to honesty and integrity, it is equally necessary to examine the system that made such deception possible.

Cloning, Organism↗

Evangelical renewal therapy: a proposal for integration of religious values into psychotherapy.

The importance of incorporating religious values into psychotherapy that is used in treating the mental health needs of Evangelical Christians was examined. Rationality and pathology were analyzed from an Evangelical Christian perspective. Guilt was seen as the primary psychological consequence of self-defeating behaviors. Evangelical Renewal Therapy was offered in response to the apparent need for a religious psychotherapy that would focus on the mental health needs of Evangelical Christians. The Atheistic Ideation Complex purports that atheistic ideations as measured by the Atheistic Ideation Reference Scale lead to unwanted emotional consequences. Repentance, the process of change in Evangelical Renewal Therapy, is achieved through the analysis of moral action, rebuke, confession, prayer, recompense, and mortification through good works.

Combined Modality Therapy↗

Lessons from an English opium eater: Thomas De Quincey reconsidered.

Thomas De Quincey published his autobiographical Confessions of an English Opium Eater in 1821. The publication both fascinated and outraged its 19th-century readers. Heated debate followed on such topics as: the causality of opiate use; self-inflicted suffering and responsibility; the impact of availability and environment; therapeutic addiction; controlled use; the emergence of dependence; tolerance; withdrawal techniques; hazards; the impact of advertising. Many of these topics remain subjects of debate and causes for concern today. We would be well advised to study the questions and debates of a century and a half ago.

England↗

Biting of anthropophilic Culicoides fulvithorax (Diptera: Ceratopogonidae), a vector of Mansonella perstans in Nigeria.

Anthropophilic Culicoides were investigated in a rural community endemic for Mansonella perstans in Ijebu North area of western Nigeria between December 2003 and October 2004. Three hundred and fifty-nine adults of Culicoides fulvithorax collected by human bait in the morning were dissected for Mansonella perstans larvae, and 1.95% of infection rate was found. Seasonal abundance of C. fulvithorax was investigated by monthly biting rates, and showed that higher prevalence was observed in rainy season, with peak in September. Culicoides prevalence was positively correlated with rainfall and relative humidity, but not temperature. Human perceptions on the behavior of these biting midges were determined by interviewing 854 self-selected villagers, of which 86.5% of the interviewees confessed having experienced Culicoides bites. Between 76.5 and 99.1% of the various age groups complained body reactions to Culicoides bites. Itching was the most frequent body reaction. No interviewees associated Culicoides with transmission of any parasitic infections. The results showed need to adequately control Culicoides in the community.

Adolescent↗

[Study of hypertensive very elderly population admitted to a regional hospital].

OBJECTIVES: To analyse the characteristics of the hospitalized very elderly people (age equal or superior to 80 years) with hypertension (HT). PATIENTS AND METHODS: Prospective study including the patients with HT who need hospitalization in our medical institution. Data collected were: demographic, clinical parameters, factors of vascular risk, hygienic-dietetic strategies, pharmacological treatment, cause of hospitalization, and biochemical determinations. RESULTS: There were included 92 very elderly patients (71 women); they represent 14 % of total hospitalized people. Two third parts had not realized academic studies, being 60 % of rural origin. Almost the half (41 %) was diabetic, and 27 % had dyslipidemia. Overall 62 % had 4 or more factors of cardiovascular risk. The hospitalization was related to the HT in the half of the cases, and 61 % had already previously some cardiovascular event. The lifestyle modifications more frequent were: not to smoke (95 %), no alcohol (81 %), and diet without salt (75 %). Diuretics were the most frequent anti-hypertensive agent used. The global mortality was two times superior to the hypertensive population < 80 years in the same period. CONCLUSIONS: The very elderly hypertensive patients of our study are fundamentally women, of rural origin and without academic studies. The above mentioned hospitalization is attributable directly to the HT in the half of the cases. They are a population of high cardiovascular risk, with previous events cardiac and cerebral-vascular. They confess to realize frequently the hygienic-dietetic strategies recommended. The diuretics are the anti-hypertensive agents most used for the HT. Since it was of waiting for the mortality in this group it is high.

Aged, 80 and over↗

Induction of labour.

The only justification for adding to the extensive literature on induction of labour is to bring together relatively inaccessible but relevant data for the general reader. Some of these data refer to current practice, and some to patients' experiences. The conflicting value systems of some doctors and some patients are also discussed. The writer, a self-confessed armchair critic, makes some suggestions about ways of reducing disagreement about elective induction of labour.

Attitude to Health↗

After the layoffs, what next?

Harry Denton, the CEO in this fictional case study, has been caught off guard. As the head of Delarks, a venerable department-store chain in the Midwest, he has engineered a remarkable turn-around in only a year. Sales have rebounded, and Wall Street is applauding. Sure, a few trees were felled in the process--to make room for new growth, Denton had to clear out 3,000 pieces of what he privately refers to as "dead-wood"--but he'd saved the company. Didn't people understand that? Not exactly. When Delarks's head of merchandising defects to a competitor, Denton is shocked to realize that many of the survivors, in fact, have had it with him and with the company. The last straw was the recent closing of the Madison store, which Denton announced without warning to anyone--not even the company's head of HR, Thomas Wazinsky, a supposedly trusted adviser. In the wake of that coup, store employees from Wichita to Peoria are wondering, Are we next? The rumor mill says that many of them are considering leaving before Denton can inflict the next blow. And senior managers are not immune to the fear and anger. Even Wazinsky, one of the few links to Delarks's proud past, confesses to Denton, "I'll bet you're thinking of firing me." Denton has to act--and fast. He calls a "town meeting" for the 600 employees of the St. Paul store. The plan: rally the troops. Instead, Denton is routed. Angry questions are hurled at the CEO, and he is forced to beat a hasty retreat through the back door. Five experts offer advice on how to revive morale at the successful but troubled company.

Chicago↗

[Lethal child abuse (through the use of physical force) in the German Democratic Republic during the period 1 January 1985 to 2 October 1990. Results of a multicenter study].

UNLABELLED: No reliable data are available on cases of lethal child abuse (by active force) in the area of the former German Democratic Republic. In a multicenter study we therefore examined the police and court records for such cases occurring in the period 1 January 1985 to 2 October 1990 in the entire area of the former German Democratic Republic. RESULTS: The study center received information on 39 cases of lethal child abuse which correspond to approximately 7 cases per year. However, a low percentage of undetected crimes which cannot be determined more precisely has to be taken into consideration. Almost 40% of the victims were younger than 1 year, 73% of the victims showed indications of repeated ill-treatment. The effects caused by using direct blunt forces, against the head in particular, were by far the most frequent causes of death. The male contact person (the victim's father, brother or stepfather as well as the life companion of the child's mother in particular) killed the child in most of the cases. As far as it is known, 37% of the male/female offenders suffered from chronic alcoholism; 32% of the male/female offenders were under the influence of alcohol when the crime happened. 83% of the male/female offenders who were found guilty made a confession shortly after the crime had happened or during the interrogations. Almost all the male/female offenders were sentenced to prison (the duration of the imprisonment varied between one year and for life). Due to the considerably lower section rate compared to the one in the German Democratic Republic, it is to fear that each second fatal child abuse is not detected in the new federal states.

Adolescent↗

Role of doctors in prevention of torture.

Torture is taking place since time immemorial. Doctors can take important part in elimination of this social evil. Torture is deliberate, systematic or wanton infliction of physical or mental suffering by one or more persons to force another person or torture victim to make confession or giving information. Torture happens to occur in 3 forms--physical, mental and/or sexual. Doctors working in prisons, police or paramilitary/military forces are most likely to confront with torture and they should follow the medical ethics, codes and conventions in true sense. MCI, IMA, WMA should play their role in educating, motivating and supporting doctors in confronting torture. NHRC and IMA should co-operate each other to protect human rights.

Humans↗

[Examples for use of the STR systems in stain assessment with special reference to Y chromosome systems].

The authors describe 3 cases where Y-chromosomal systems were used for typing the biological traces. In the first case, a murder, for the major amount of cell material found on a dish towel (and analysed two years after the crime) female persons were excluded for the system amelogenin and Y-chromosomal systems. A brother of the victim could not be excluded for autosomal STR-systems. Upon confrontation with the results of the DNA-analysis (among other things), this brother confessed the murder of his sister some days later. He was found guilty by the court. In the second case described, a rape of two girls, many traces were analysed parallely with Y-chromosomal and autosomal PCR-systems. The objects where male DNA matching the suspect were found (a paper tissue, a sweat shirt and the knickers of the girls), also showed small amounts of alleles matching with the suspect for autosomal systems, while the major part in these systems was from the girls. The suspect was sentenced to many years imprisonment. In the third case, a possible rape of a young woman, a stained microscope slide of a vaginal swab had to be examined. Microscopically a few sperm heads could be seen in a surplus of leucocytes. The male proportion could be analysed only in the Y-chromosomal systems, not in the autosomal ones. For the frequency calculation of the Y-chromosomal allele combination the haplotype data bank of the Institute for Legal Medicine of the Humboldt university in Berlin was indispensable.

Adult↗

Signature murders: a report of the 1984 Cranbrook, British Columbia cases.

Two females, Denean Worms and Brenda Hughes, were murdered in separate events in Cranbrook, British Columbia in 1984 within three months of each other. Terrence Wayne Burlingham was found guilty of both murders and he appealed. The Supreme Court of Canada granted Burlingham a new trial in the Worms case, but no evidence from Burlingham's confession nor the murder weapon could be used. The Crown counsel requested an evaluation of the two murders to determine if they were committed by the same person. The analyses of those murders revealed that they were linked by a personal "signature" of the killer. The murder cases reported here demonstrate a control-oriented signature. The killer used a .410 shotgun as his method of control and death, engaged in overkill of each victim by shooting them twice in the head, and left the victims in sexually degrading positions. Another signature feature was the absence of typical wounds to the victims which would be expected from a serial sex offender. All of these characteristics, in combination, accounted for this killer's personal expression.

Adolescent↗

Petechiae of the baby's skin as differentiation symptom of infanticide versus SIDS.

The successive killing of three siblings by their biological mother at two-year intervals is described. The children were 367 days, 75 days and 3 years old. Although sudden infant death syndrome (SIDS) or interstitial pneumonia could not be ruled out as the cause of death in the two younger children, who were killed first, the third child exhibited discrete signs of violence in the mouth and throat area which were interpreted as proof of infanticide. All three children had petechiae of the skin of the face and throat, the upper thorax, the shoulders and the mucous membranes of the mouth. None of the children exhibited signs of a disease-related hemorrhagic tendency. After the mother was convicted of murdering the three-year-old boy by smothering in combination with compression of the thorax, she confessed to having killed the other two children in a similar manner. In the absence of hemostatic disease, the presence of petechiae of the skin extending over the entire drainage area of the Vena cava superior can be regarded as evidence of an increase in pressure in the thoracic cavity secondary to obstruction of the airways with simultaneous chest compression.

Asphyxia↗

Homicidal commotio cordis in two children.

This paper's objective is to describe two cases of fatal commotio cordis resulting from the deliberate striking of children's chests by adults with their fists. These deaths involve two male children, ages 3 years and 14 months. The clinical histories, events in the households prior to the deaths, behaviors of the children, autopsy findings, and investigation results are all similar. In both cases, fatal blows were delivered to the anterior chest with a closed fist. Both children collapsed immediately, unable to be resuscitated. Confessions were obtained in both cases by investigators soon after the children's deaths. Autopsies showed chest contusions in only one child, presumably due to knuckle impact. The cardiac rhythms noted by paramedics were ventricular fibrillation and asystole. Due to the lack of physical findings, an immediate and thorough investigation is critical. An accurate history of events preceding death must be obtained.

Child Abuse↗

God, mammon and the physician: medicine in England before the college.

Medieval medical practice has all too often been depicted by historians as ineffective, overpriced and riddled with superstition. Yet the physician, who boasted an impressive range of academic accomplishments, exercised considerable influence in political, religious and cultural affairs. How was this achieved? The overwhelming authority of the Church, in an age of high mortality, when life was generally painful as well as short, helps to explain an apparent paradox. For the practitioner, who was often also a priest, dealt with spiritual as well as earthly diseases, plumbing the recesses of men's souls while he examined their bodies. He was a confidant and mentor, offering advice on all aspects of the human condition. Since physical suffering was often regarded as a consequence of sin, confession loomed large in treatment. Indeed, the practice of both medicine and surgery was regulated by canon law, which looked beyond mere physical fitness to the quest for eternal salvation.

Cultural Characteristics↗

Oral chemotherapy for colorectal cancer: some economic considerations.

In the formal medical curriculum, little has been provided to prepare the clinician for an understanding of the economics of health care. The questions are often far more complicated than they initially appear to be, and the techniques and terminology used in evaluation of these questions are often foreign to many health-care providers. This brief essay, written by an author who confesses to being an economic layman, will attempt to discuss and clarify some terms and techniques used in the economic analysis of health care. In that context, and recognizing the limitations of the techniques available, an attempt will be made to address the question of the economic impact of oral fluorinated pyrimidines on the management of colorectal cancer.

Administration, Oral↗

Six months follow-up of patients with methamphetamine psychosis.

BACKGROUND: It has been nearly 50 years since the psychotic state caused by amphetamine was first reported. However, the prognosis of methamphetamine (MAP) psychosis and its relationship with chronic schizophrenia are still vague. Some authors preferred MAP psychosis model of schizophrenia, while other studies found difference between the two groups of patients in the aspects of negative symptoms. METHODS: In this study we followed 21 psychiatric inpatients with diagnosis of MAP psychosis. Schedule for affective disorders and schizophrenia (SADS), scale for assessment of negative symptoms (SANS) and global assessment scale (GAS) were used for evaluation of these patients during admission and six months after discharge. RESULTS: Seventeen patients were interviewed and eight of them confessed reuse of MAP. The follow-up examinations found decreased total scores of delusion and hallucination in SADS and increased GAS scores. The SANS scores of the MAP psychotic patients in this study were lower than moderate level. No significant change could be found for most SANS subcategory scores except some items. CONCLUSIONS: Most MAP psychotic patients followed in this study improved much in six months. The results of the SANS evaluation and the clinical course for six months indicated that the MAP psychosis is a psychotic disorder different from chronic schizophrenia.

Adult↗