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Clostridium welchii food poisoning.
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Bacterial contamination of hospital food with special reference to Clostridium welchii food poisoning.
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[Comparative clinico-morphological characteristics of peace-time anaerobic infections].
Altogether 26 cases of anaerobic infection (AI) of various etiology were analysed. Local tissue ischemia and operations on gastrointestinal organs in patients with secondary immunodeficit conditions are the factors facilitating the development of AI. The distinction is made between clostridial AI with a rapidly progressing gaseous gangrene and the non-clostridial AI with a slower course of a serous-purulent phlegmoma. Anaerobic myositis is observed in all forms of AI. Depending on the localisation of AI, anaerobic cellulitis and fasciitis are mentioned which occur mainly in non-clostridial AI. The treatment of AI and the mechanisms of death are discussed.
Clostridium perfringens pleuropulmonary infection and septic shock: case report and population-based laboratory surveillance study.
We report a rare case of necrotizing pneumonia, empyema, and septic shock caused by Clostridium perfringens. Population-based laboratory surveillance was subsequently conducted that identified an annual incidence of invasive C. perfringens disease of 0.83 per 100,000 population with a striking age-related increased risk for acquisition.
Fatal clostridial sepsis after spontaneous abortion.
BACKGROUND: Although obstetric mortality due to complications of Clostridium perfringens infection is rare at present, we report a case of fatal clostridial sepsis secondary to a septic spontaneous abortion. CASE: A woman at 6-8 weeks' gestation presented with vaginal bleeding and abdominal pain. Although afebrile, the patient was hypotensive, tachycardic, and tachypneic. Physical examination was remarkable for a 10-weeks'-gestation-size uterus, mild pelvic tenderness, a closed cervix without signs of trauma, and moderate vaginal bleeding. Laboratory studies were consistent with infection, hemolysis, and coagulopathy. Sonography demonstrated echolucencies consistent with gas formation in the endometrial cavity. Despite fluid resuscitation, transfusions, antibiotic therapy, and a dilation and curettage, persistent vaginal bleeding required an emergency hysterectomy. Hypotension ensued, and despite aggressive resuscitation attempts, the patient died. CONCLUSION: Rare cases of fatal sepsis secondary to pelvic infection with Clostridium perfringens continue to occur. Hemolysis, anuria, coagulopathy, and characteristic sonographic findings should heighten suspicion of this potentially fatal infection.
[Protective effect of placental lysozyme on experimental infections in mice induced by Clostridium tetani, Staphylococcus aureus and Diplococcus pneumoniae].
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Bacterial food poisoning: what to do if prevention fails.
The numerous etiologies of food poisoning make assessment of this disease a cultural, bacteriologic, chemical, gastronomic, and epidemiologic research project. Cautious investigation and study of etiologic possibilities are most stimulating intellectual exercises and obviously benefit the patient. Often, a case of food poisoning necessitates interaction with the local health department in search of the causative agent before other people are afflicted. A thorough knowledge of this field is essential to provide reasonable care to the millions "poisoned" by food annually.
[Infection of surgical wounds with Clostridium].
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Treatment of anaerobic infections.
The anaerobic syndromes of gas gangrene and tetanus are due to systemic intoxications that develop following infection with clostridia at some site of trauma. Classically, these conditions developed as complications of accidental trauma, the spore-forming anaerobes being derived from the inanimate environment. While tetanus remains typically an exogenously derived disease, gas gangrene more frequently presents as an endogenously derived complication of elective surgery. Their treatment is briefly discussed, including the role of antimicrobial therapy. During the last decade there has been an increasing awareness of the importance of non-sporing anaerobes as a major cause of serious endogenously derived infections in man. They are not only a common cause of postoperative infection following appendicectomy, and acute and elective colorectal and gynaecological surgery, but they also cause a wide variety of infections at other sites, usually secondary to some preexisting pathology. In the management of these infections, surgical drainage of pus, when present, is of first importance. Systemic antimicrobial therapy, directed against the anaerobes is dramatically effective both in the management of established infections, and in their prevention in patients known to be at risk.
Studies on the relationship between intestinal flora and cecal coccidiosis in chicken.
The bacteriological and histopathological changes in the ceca of young chickens after being infected with sporulated oocysts of Eimeria tenella were investigated. Lactobacilli and bifidobacteria showed remarkable decrease in number on the 5th day after infection, when shizont and gametocyate came to appear, and destruction of mucosa along with severe haemorrhaging was noticed. Other predominant bacteria like bacteroidaceae, catenabacteria and peptostreptococci showed only moderate and temporal decrease in number during the infection. Clostridium perfringens prolifereated after the 5th day post infection following the decline of lactobacilli and bifidobacteria. Proliferation of clostridia was so intense that the number was almost million times greater than that of the uninfected chicken at its peak on the 7th day after infection. Enterobacteria also showed a moderate but persistent increase in number. Most bacteria came to the normal population on the 10th day after infection. As for lactobacilli, bifidobacteria, clostridia and enterobacteria, the disturbances were still noticeable on the 17th day after injection. Antagonism between proliferated bacteria (clostridia and enterobacteria) and lactic acid bacteria (lactobacilli and bifidobacteria) whose intensity is suppose to be related to the cecal mucosa is suggested during cecal coccidiosis in chickens.
Enterotoxaemia of sheep: Clostridium welchii type D in the alimentary tract of normal animals.
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Infective endocarditis due to Clostridium sordellii.
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Anaerobic infections of the female genital tract.
Anaerobic bacterial organisms are a frequent cause of female genital tract infections. There has been a lack of appreciation of the significant role anaerobes play in obstetric and gynecologic infections. Utilization of newer appropriate anaerobic culture techniques has shown the importance of these organisms as pathogens in serious infections of the genital tract. Many species of anaerobic bacteria appear to be part of the normal microflora of the lower genital tract in female subjects. Similar organisms are frequently isolated from pelvic infections. Bacteroides, anaerobic cocci, and Clostridia are the most commonly isolated anaerobes associated with clinical infections. The clinician must recognize the presence of anaerobic infections, utilize proper anaerobic culture methods, and institute appropriate antibiotic and/or surgical therapy.
CLOSTRIDIAL INFECTIONS WITH SPECIAL REFERENCE TO CLOSTRIDIUM PERFRINGENS.
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Infective endocarditis due to Clostridium histolyticum.
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Mycotic right coronary artery aneurysm: CT and MR diagnosis.
A clostridial mycotic aneurysm of the right coronary artery was diagnosed by the use of multiple imaging modalities including gated magnetic resonance imaging. Percutaneous drainage was performed as a palliative measure in hope of avoiding repeat sternotomy.
Effect of cyclophosphamide on experimental infection of mice against Clostridium chauvoei.
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