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Results for “CAT SCRATCH DISEASE”

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At least 469 records · Page 26Linked to original sources
PubMed1995

Uncomplicated cat-scratch disease: findings at CT, MR imaging, and radiography.

PURPOSE: To describe the epidemiologic, clinical, and imaging features of cat-scratch disease (CSD) to facilitate prompt recognition and noninvasive diagnosis of this condition. MATERIALS AND METHODS: Eight otherwise healthy patients with pet cats presented with the subacute onset of epitrochlear, axillary, or groin masses. All underwent cross-sectional imaging with computed tomography (CT) (n = 1) or magnetic resonance (MR) imaging (n = 7). Five patients underwent radiography of the elbow. RESULTS: In all patients, MR imaging and CT showed a poorly defined soft-tissue mass with extensive surrounding edema in an efferent lymphatic distribution. Radiography revealed only soft-tissue edema in two patients and an ill-defined soft-tissue mass with soft-tissue edema in three patients. Six patients underwent biopsy; the findings of all pathologic specimens supported the diagnosis of CSD. No patients underwent serologic evaluation. All patients were asymptomatic within 4 weeks of beginning antibiotic therapy. CONCLUSION: CSD should be considered in all patients with upper extremity or head and neck adenopathy and a history of cat exposure. Although generally not required for diagnosis, cross-sectional imaging will reveal a mass with surrounding edema in an area of lymphatic drainage.

Adolescent↗
PubMed1999

Ocular manifestations of cat-scratch disease.

Bartonella henselae has only recently been isolated, characterized, and found to be the principal cause of cat-scratch disease (CSD). The availability of specific serologic investigations has allowed the recognition of a spectrum of ocular CSD syndromes that previously were ill defined and considered idiopathic. The primary inoculation complex causing regional lymphadenopathy is represented in the eye by Parinaud's oculoglandular syndrome; B. henselae is the most common cause. Leber's neuroretinitis has been identified for 80 years, and new data suggest that it is commonly a manifestation of CSD; the extent of the association remains to be determined. CSD optic neuritis is also described. The vitreoretinal manifestations include anterior uveitis, vitritis, pars planitis, focal retinal vasculitis, a characteristic retinal white spot syndrome, Bartonella retinitis, branch retinal arteriolar or venular occlusions, focal choroiditis, serous retinal detachments, and peripapillary angiomatous lesions. The pattern of ocular disease in AIDS-associated B. henselae infections is poorly delineated; unusual manifestations include conjunctival and retinal bacillary angiomatosis. The benefit of antimicrobial therapy for CSD in immunocompetent individuals has been difficult to establish, partly because most infections are self limited. Empirically, azithromycin, ciprofloxacin, rifampin, parenteral gentamicin, or trimethoprim-sulfamethoxazole provide the best therapeutic choices to minimize damage to the eye.

Anti-Bacterial Agents↗
PubMed1979

Cerebral arteritis in cat-scratch disease.

Acute right hemiplegia and transient expressive aphasia occurred in a 7-year-old girl a few days after nonspecific constitutional symptoms and the appearance of a large right submandibular lymph node. Biopsy of this node and lack of other evident cause suggested a diagnosis of cat-scratch disease. Carotid arteriography showed a localized arteritis of the supraclinoid part of the left internal carotid artery and the left middle cerebral artery, involving also some lenticulostriate vessels. Computerized tomography demonstrated infarction in the left internal capsule. The size of this infarct and the angiographic abnormalities improved 6 weeks after onset, and coincided with clinical recovery. Cat-scratch disease may have caused the localized arteritis.

Arteritis↗
PubMed2004

First isolation of Bartonella henselae type I from a cat-scratch disease patient in Japan and its molecular analysis.

We isolated Bartonella henselae from an inguinal lymph node of a 36-year-old male patient with cat-scratch disease. The patient had many areas of erythema on his body, swelling of the left inguinal lymph nodes with pain and slight fever. The diagnosis was made on the basis of polymerase chain reaction for B. henselae DNA from the lymph node biopsies and blood sample, and isolation of the organism, histology of the lymph node and serology with an indirect immunofluorescent antibody test. We also analyzed the genome profiles for five strains of 90 isolates from the lymph node by pulsed-field gel electrophoresis after Not I endonuclease digestion. We found two different genomic profiles. These results suggest that the patient had been either co-infected or re-infected with two genetically different strains of B. henselae.

Adult↗