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Results for “Autobiography”

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At least 469 records · Page 26Linked to original sources
PubMed1989

Concepts and models for DNA repair: from Escherichia coli to mammalian cells.

Much of our early understanding of the mechanisms of excision-repair and its roles in maintaining genome integrity and cellular viability was derived from studies with bacteria. In fact, the discoveries of damage excision and repair replication were made in ultraviolet (UV)-irradiated Escherichia coli. Recent advances in recombinant DNA technology have helped to further our understanding of the manner in which mammalian cells deal with damage in their complex genomes. These include the discovery that expressed genes may be preferentially repaired and, furthermore, that the transcribed DNA strand, for some types of damage, is selectively repaired within an active gene. The latter finding has now been documented in E. coli as well, so it is likely that it is of widespread importance as a mechanism to ensure the expression of active genes in otherwise damaged cells. It is certain that studies with bacterial systems as models will continue to have an important impact on the development of the field of mammalian DNA repair.

Animals↗
PubMed2001

Hippocampal complex and retrieval of recent and very remote autobiographical memories: evidence from functional magnetic resonance imaging in neurologically intact people.

It has been argued that the role of the hippocampus in memory is time-limited: during a period of memory consolidation, other brain regions such as the neocortex are said to acquire the ability to support memory retention and retrieval on their own. An alternative view is that retention and retrieval of memory for autobiographical episodes depend on the hippocampal complex, regardless of the age of the memory. We examined the participation of the hippocampal complex in a functional magnetic resonance imaging (fMRI) study in which participants were asked to recollect autobiographical events that occurred either within the last 4 years or more than 20 years ago. We found equivalent levels of hippocampal activation in both conditions in all participants (N = 10). In addition, activation in neocortical regions did not differ as a function of the age of the memory, even though most of the recent memories recalled were less than 2 years old and the remote memories more than 35 years old. The results support the notion that the hippocampal complex participates in retention and recovery of even very old autobiographical memories, and place boundary conditions on theories of memory consolidation.

Autobiographies as Topic↗
PubMed2004

One form of self-analysis.

Beginning with Freud, psychoanalysts have discovered media through which they may achieve a self-analytic experience (for example, by use of dreams, fantasies, reveries, memories, and even visual images). Each of these media is a kind of "fiction" created by the analyst that provides an imaginative space where he or she may gain access to unconscious life. The author demonstrates how a generative self-analytic experience may be accomplished through the medium of psychoanalytic writing: a fictional autobiographical form of writing through which a self-analytic experience is created that has much in common with the analytic experience created by the analyst and analysand.

Autobiographies as Topic↗
PubMed2006

Clinician to frontline soldier: a look at the roles and challenges of army clinical psychologists in Iraq.

Psychologists have a long and respected history of service during wartime that dates back to World War I. From the early days of scientific personnel selection, clinical psychologists have made a number of wartime contributions. Today, Army clinical psychologists serving in Iraq are providing behavioral health services as both clinicians and prevention specialists in order to meet the psychological and emotional needs of service members abroad. They are also performing as Army officers and soldiers contributing to the success of military operations as a whole. The authors, two clinical psychologists and Army officers currently deployed to Iraq, provide a small glimpse into the clinical and personal opportunities and challenges faced by wartime Army clinical psychologists.

Autobiographies as Topic↗
PubMed1989

Freeze-fracture: a personal history.

The sequence of events leading to the development of freeze-fracture replication is described. Subsequent developments discussed include complementary replicas, replica interpretation with stereo micrograph and reversal negatives, replica reinforcement, and control of resistance evaporation.

Botany↗
PubMed2004

Cheiron's origins: personal recollections and a photograph.

When the Cheiron Society convened at the University of New Hampshire for its thirty-fifth annual meeting in June 2003, members were returning to the site where the proposal to establish a new scholarly organization to promote research in the history of the behavioral and social sciences originated in the summer of 1968. I was witness to Cheiron's birthing and have been closely involved in its evolution over the years, and so was asked to comment on the circumstances that produced what has become a vibrant source of stimulation and support for those of us interested in the field. (For other published accounts of the Institute and Cheiron's founding see Brozek, Watson, & Ross, 1969, 1970; Goodman, 1979, 1982; Watson, 1972, 1975; and Weyant, 1968.)

History, 20th Century↗
PubMed2004

Michael J. Fox and his Parkinson's disease.

Michael J. Fox was a popular and successful film and television comic actor who developed Parkinson's disease at the age of 29 years. His recently published book, Lucky Man, structured around the story of his Parkinson's disease, is an amusing, briskly paced yet introspective memoir that covers the first 40 years of his life. Although quite anecdotal, it contains interesting observations on the preclinical phase of the disorder, evolution of motor fluctuations, and tactics for pharmacological treatment.

Adult↗
PubMed2002

What have I learned from single-fiber electromyography?

The author recounts the lessons taught by single-fiber electromyography that reached him through the medium of low-frequency attenuation and a small concentric needle electrode. He concludes that it is difficult to imagine practicing electromyography today without the benefits that have flowed from the work of Erik Stålberg and his colleagues.

Electromyography↗