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At least 469 records · Page 26Linked to original sources
PubMed2006

A modular approach to anion binding podands: adaptability in design and synthesis leads to adaptability in properties.

Progress in the development of a modular approach towards flexible anion-binding and sensing systems is reviewed within the context of related developments in conformationally flexible anion- and salt-binding hosts. The transferability of concepts and structural features across chemically distinct systems is emphasised along with the use of modular components in polymer and gel-phase systems.

Journal Article↗
PubMed1986

The relationship between traditional and innovative sex-role adaptations and innovative sex-role adaptations and sexual satisfaction among a homogeneous sample of middle-aged Caucasian women.

This paper examines sexual experiences and satisfaction among a homogeneous sample of middle-aged, middle and upper socioeconomic status, Caucasian women. The hypothesis that women who occupy more traditional social roles on the traditional-innovative continuum would have greater sexual satisfaction is rejected. Relationships among a variety of indicators of sexual satisfaction and position on the innovative-traditional continuum indicated lack of consistent directionality or strong associations. Voluntary association memberships serendipitously emerged as a relatively strong indicator of social activities related to sexual satisfaction.

Employment↗
PubMed2006

Comparing adaptive and non-adaptive algorithms for cancer early detection with novel biomarkers.

It may be possible to reduce cancer mortality by monitoring the concentrations of serum biomarkers over time in men and women to detect their cancer early, when it is most curable. The simplest approach to using a biomarker for screening is to sequentially use fixed thresholds as a means to determine an abnormal test (e.g., PSA exceeding 4 mg/ml, CA 125 exceeding 30 U/ml). Alternatives to the simplest single threshold (ST) rules include more sophisticated algorithms that make use of screening history that accumulates over time and determines abnormal tests using individualized reference ranges. Although in principle longitudinal algorithms should out perform fixed threshold rules, the actual benefit gained will depend on behavior of the biomarker, the screening algorithm, and the screening frequency. Little information has been available to help predict when conditions should compel the adoption of the more sophisticated algorithms and when conditions suggest the simpler algorithms should suffice, or indeed be preferred. In this manuscript we evaluate the conditions under which one should expect great benefit, and when one should not expect benefit, by comparing the ability of simple and complex algorithms to detect cancer early under a variety of biomarker behaviors and screening frequencies.

Algorithms↗