Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “STING”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 451 records · Page 25Linked to original sources
PubMed2002

Anaphylaxis due to Red Imported Fire Ant sting.

The invasive Red Imported Fire Ant (Solenopsis invicta Buren) is well established at two locations in the Brisbane area, and we report a patient with anaphylaxis after a sting. The potential for anaphylactic events in Australia due to S. invicta will be greater than for native ants because of its unusual venom, its habit of forming supercolonies in grassy areas, and its aggressive group territorial defence, which can result in multiple stings.

Anaphylaxis↗
PubMed2002

[Structural characteristics of nematocyst stinging threads from the parasitic cnidarian Polypodium hydriforme].

The structure of discharged nematocyst stinging threads present in free-living individuals of Polypodium hydriforme was studied by scanning and transmission electron microscopy. Not all cnidae of P. hydriforme proved to be atrichous isorhizas (as previously was accepted), but only one of the five nematocyst categories studied. A unique feature of P. hydriforme nematocysts was revealed: their stinging threads possess two strands of spines, rather than 5 or 3, as in Narcomedusae and other Cnidarians, respectively. This fact supplements the evidence in favour of P. hydriforme being a rather isolated branche in the phylogenetic tree of Cnidaria.

Animals↗
PubMed2003

[Up to allergy specialists' consideration: did Pharaoh Menes die of a wasp sting?].

Several allergologists interested in allergies to wasp venom, pass a seemingly probable information that the first Egyptian pharaoh, Menes, was allergic to the venom of stinging insects, and died of an insect sting while on a long journey, somewhere in the area of present-day Great Britain. A relief decorating the pharaoh's sarcophagus and the tomb's walls is to prove the historicity of this event. The whole story is a typical hoax. Insufficient historical sources do not confirm the thesis that Menes visited Europe. The tomb which is considered to be his burial site, contained no sarcophagus, reliefs or paintings. The above-mentioned relief is a contemporary illustration which should raise suspicions even of a layman who looked at it carefully. It is interesting why so many respectable scientists believe the hoax and quote it without previous verification.

Animals↗
PubMed2004

F-actin and beta-tubulin localization in the myxospore stinging apparatus of Myxobolus pseudodispar Gorbunova, 1936 (Myxozoa, Myxosporea).

To understand the discharge mechanism of Myxozoan polar capsule (cnida) it is necessary to verify the role of major cytoskeletal proteins in the process. With this aim F-actin and beta-tubulin localization in spores of myxosporean developmental phase (in myxospores) of Myxobolus pseudodispar Gorbunova, 1936 has been studied under confocal scanning laser microscope using phalloidin fluorescent staining of F-actin and indirect anti-beta-tubulin immunostaining. F-actin has been detected in walls of the stinging tube invaginated into the polar capsule of myxospore. The fact suggests the contractile proteins involvement in the process of myxozoan polar capsule extrusion. In addition, the cytoplasm of amoeboid sporoplasm inside the spore cavity is stained by phalloidin. A polar cap with strong beta-tubulin immunoreacton is observed at the front pole of fully mature myxospore above the outlets of the polar capsule discharge channels. The role of the beta-tubulin cap is supposed to be similar to that of the cnidarian cnidocil made of microtubules. The weaker beta-tubulin immunoreactivity has been found in stinging tubes, in polar capsule walls as well as in the suture line of spore walls and in the cytoplasm of amoeboid sporoplasm. The involvement of cytoskeletal proteins in the process of polar capsule extrusion is discussed. A hypothesis on the myxozoan polar capsule discharge mechanism is suggested. The mechanism of myxozoan cnida discharge is compared with that of cnidaria.

Actins↗
PubMedDate not supplied

Evaluating the efficiency of a combination of Pygeum africanum and stinging nettle (Urtica dioica) extracts in treating benign prostatic hyperplasia (BPH): double-blind, randomized, placebo controlled trial.

OBJECTIVES: In spite of its historical use, published data about phytotherapic products is characterized by the absence of well conducted studies, leading to conflictive and indefinite results about efficiency and safety of theses drugs. In that sense, we have analyzed the results of a combination of Pygeum africanum and stinging nettle (Urtica dioica) extracts in patients with benign prostatic hyperplasia (BPH), based in a double-blind, randomized, placebo-controlled protocol. MATERIALS AND METHODS: We have selected, according to inclusion and exclusion criteria, only patients with >or=50 years, presenting urinary symptoms assessed by the International Prostatic Symptoms Score (IPSS), with minimum score of 12, and Quality of Life (QoL) index of at least 3 points, rectal examination consistent with BPH, and maximum urinary flow rate (Q(max)) between 5 and 15 mL/s. Phytotherapic and placebo groups were formed by 27 and 22 patients, respectively. The major variables analyzed during the study were IPSS variation, Q(max), and side effects. Reduction of >or=30% and >or=50% in IPSS were the parameters used to define a clinically significant response (CSR). We have also analyzed >or=30% and >or=50% Q(max) increases. RESULTS: After six months of treatment we did not observe significant differences in clinical improvement potential between the phytotherapic combination and placebo groups. Percent IPSS drop of 21.6% in the phytotherapic group was similar to 19.7% obtained in the placebo group (p=0.928). Neither we observed any difference (p=0.530) for QoL improvement between phytotherapic (9.26%) and placebo (5.98%) groups. The alterations of Q(max) followed the trend line observed in clinical data, with no significant difference (p=0.463) in Q(max) increasing percent between phytotherapic (17.2%) and placebo (13.3%) groups. The CSR evaluation of clinical and urodynamic data was also similar between the groups. CONCLUSION: The combination of 25mg Pygeum africanum and 300mg stinging nettle extracts produced clinical and urodynamic effects similar to placebo in a group of HBP patients.

Journal Article↗
PubMed2005

[Bee sting of the cornea--a case report].

Published reports on bee stings of the cornea are rare, especially when it occurs in the winter season. have the potential for causing serious ophthalmologic problems. The venom in the sting can produce toxic and immunologic reactions. The result is acute ocular inflammation, which is usually confined to the anterior segment of the eye. The aim of our work is to present a 84-year-old man who was stung by a bee on the left cornea, while taking care of a swarm of bees. The main symptoms were pain, oedema of eyelids, conjunctival injection, keratitis and iritis. The sing was present in the cornea. After the removal of retained stinger and pharmacological treatment we observed rapid improvement.

Aged↗
PubMed1992

[The STING procedure: subureteral teflon application in vesico-ureteral reflux].

Apart from open surgical correction of vesicoureteral reflux an endoscopic technique exists in which teflon paste is injected under the refluxing ureteral orifice; this is known as the STING procedure. We describe this technique, which if necessary may be repeated. The results in our patients are comparable with results from literature, with 21/23 (91%) of the ureters without reflux after treatment. The advantages and disadvantages of this technique are discussed. The good results, the short hospital stay, and the minimal perioperative morbidity favour the STING procedure when compared with the open surgical technique, and make it applicable as a good alternative to open surgical technique.

Adolescent↗
PubMed1989

Medical grand rounds. West Virginia University Health Sciences Center. Bites and stings. Part 1. Spiders.

Most animals can bite or sting. In narrowing the kingdom down to those that harm humans, the field still is vast. It would be interesting to explore the rich variety of pathology produced in us by moray eels, lionfish, sea urchins, jellyfish, sting rays, fire ants, kissing bugs, flies, lice, mosquitoes, ticks, mites, fleas, puss caterpillars, centipedes, snakes, dogs and cats, camels, and myriad other creatures including homo sapiens (not a trivial biter)--but for this grand rounds, the topic will simply be spiders (Part 1), bees and vespid (Part 2). Vespids are the wasps, yellow jackets and hornets.

Animals↗
PubMed2026

VHL synthetic lethality screens uncover CBF-β as a negative regulator of STING.

Clear cell renal cell carcinoma (ccRCC) represents the most common form of kidney cancer and is typified by biallelic inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene. Here, we undertake genome-wide CRISPR/Cas9 screening to reveal synthetic lethal interactors of VHL, and uncover that loss of Core Binding Factor β (CBF-β) causes cell death in VHL-null ccRCC cell lines and impairs tumour establishment and growth in vivo. This synthetic relationship is independent of the elevated activity of hypoxia inducible factors (HIFs) in VHL-null cells, but does involve the RUNX transcription factors that are known binding partners of CBF-β. Mechanistically, CBF-β loss leads to upregulation of type I interferon signalling, and we uncover a direct inhibitory role for CBF-β at the STING locus controlling Interferon Stimulated Gene expression. Targeting CBF-β in kidney cancer both selectively induces tumour cell lethality and promotes activation of type I interferon signalling.

Humans↗
PubMed1993

Peripheral neuropathies after arthropod stings not due to Lyme disease: a report of five cases and review of the literature.

Five patients developed neurologic symptoms a few hours to 2 months after being stung by a non-hooking arthropod with immediate cutaneous reaction. The patients had no clinical or serologic evidence for Lyme borreliosis and rickettsial disease. Clinical and electrophysiologic findings were consistent with a mixed axonal and demyelinating mononeuropathy, a monomelic multiple mononeuropathy, a mononeuropathy multiplex, a radiculoneuritis, and a distal symmetric polyneuropathy. Muscle and nerve biopsies showed lymphoplasmacytic small-vessel vasculitis in all patients, and wallerian degeneration in three. These patients, and 17 others from the literature, indicate a spectrum of peripheral neuropathies occurring after insect and spider stings.

Adolescent↗
PubMed1998

Survival after massive (>2000) Africanized honeybee stings.

We report the clinical case of a man who survived a massive attack of Africanized bees (>2000 bee stings). The man experienced anaphylactic shock and multisystem organ failure (neurologic, hepatic, renal, and hematologic failure). He was treated with administration of dopamine hydrochloride, antihistaminic agents, corticosteroids, fluid and electrolyte replenishment, peritoneal dialysis, and plasmapheresis. No sequelae have been observed during follow-up.

Adult↗
PubMed1986

[Deaths following wasp stings].

Two cases of death have been reported following a wasp sting. In both cases an anaphylactic reaction after sensitization can be assumed (positive RAST result). In one case an expert witness report was required because of questions concerning insurance law (accident at work?) in addition to the cause of death. The stinger of the wasp was examined from the zoological aspect and is compared with that of the honeybee and hornet.

Accidents, Occupational↗
PubMed1975

Genetic study of the aggressiveness of two subspecies of Apis mellifera in Brazil. IV. Number of stings in the gloves of the observer.

Data are analyzed on an aspect of aggressiveness in workers from colonies of Africanized bees (Apis mellifera adansonii), Italian bees (Apis mellifera ligustica), their F1 hybrids, and backcrosses of the F1 to the parental stocks (Rothenbuhler method). The segregation values (3:1) in the backcrosses to the Africanized stock and nonsegregation in the backcrosses to the Italian stock suggest the existence of two pairs of genes (F1/F1; F2/F2 IN THE Italian bees and f1/f1; f2/f2 in the Africanized bees) which control a character defined of the number of stings in the gloves of the observer.

Aggression↗
PubMed1988

Myocardial damage after a scorpion sting: long-term echocardiographic follow-up.

A seven-year-old girl, stung by a scorpion, was hospitalized in a confused state with signs of myocarditis and pulmonary edema. In spite of clinical improvement within 24 h, 14 serial echocardiograms and electrocardiograms performed during a four-month period showed severe changes. There have been no previously published reports of echocardiographic studies showing myocardial changes after a scorpion sting.

Animals↗
PubMed2003

[Death after bee-sting].

A ten-year-old girl collapsed on the street with the signs of acute anaphylaxis. Cardiopulmonary resuscitation was unsuccessful. At the autopsy a thorn-like object was found sticking in the tongue and was later identified as the stinger of a honey bee. Witnesses reported that the girl had drunk some ice tea from a box and then had complained about pains in the mouth. Postmortem blood tests revealed increased total IgE level as well as increased levels of specific IgE against bee and wasp poisons. Cause of death was a bronchospasm caused by an allergic reaction due to a sting of a honey bee.

Age Factors↗
PubMed2002

[The tick stings! Observations on a misnomer]].

Dermatology enjoys a unique distinction of visualizing its subject matter and should attain complete unity between a dermatologic term and the clinical concept therewith expressed. Clear and definite terminology seems indispensable. Unfortunately wrong designations sanctioned by daily use are incorporated in official nomenclature. How parasitology tells us that a tick stings and that a "tick bite" is a misnomer is detailed in this article.

Animals↗
PubMed2005

Acute renal failure following multiple wasp stings.

We report the cases of two patients who developed acute renal failure following multiple wasp stings. Both patients required dialysis and recovered within 4 weeks. The kidney biopsy from one patient showed acute tubular necrosis with interstitial nephritis. One patient had complete recovery of renal function on follow-up, while the other was lost to follow-up.

Acute Kidney Injury↗