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A resource range invariance rule for optimal offspring size predicts patterns of variability in parental phenotypes.

Previous analysis of the rules regarding how much more a female should invest in a litter of size C rather than producing a litter with one more offspring revealed an invariance relationship between litter size and the range of resources per offspring in any litter size. The rule is that the range of resources per offspring should be inversely proportional to litter size. Here we present a modification of this rule that relates litter size to the total resources devoted to reproduction at that litter size. The result is that the range of resources devoted to reproduction should be the same for all litter sizes. When parental phenotypes covary linearly with resources devoted to reproduction, then those traits should also show equal ranges within each litter size category (except for litters of one). We tested this prediction by examining the range in body size (=total length) of female mosquito fish (Gambusia hubbsi) at different litter sizes. Because resources devoted to reproduction may take many forms (e.g., nest defense), this prediction may have broad applicability.

Animals↗

Perceived stress and coping resource availability as predictors of life satisfaction in young, middle-aged, and older adults.

Global satisfaction with life across three age groups (18 to 40 years, 41 to 65 years, and 66 years and above) was investigated. Multiple regressions were computed to examine the separate and joint effects of perceived stress and coping resource availability upon life satisfaction across the three age groups (N = 189). Age differences in perceived stress, coping resource availability, and life satisfaction, were also investigated. Results of this cross-sectional investigation indicated that self-appraisal measures of perceived stress and coping resource effectiveness served as moderate predictors of global life satisfaction, and that for the total sample the combined effects of perceived stress and coping resource effectiveness were better predictors of life satisfaction than either variable considered separately. Perceived stress was found to be a better predictor of life satisfaction for younger adults, and coping resource effectiveness was a better predictor of satisfaction with life for middle-aged and older adults. Significant age differences in life satisfaction, perceived stress, and coping resources were also found. The assessment of perceived stress and coping has important implications for life satisfaction among all age groups, and has particular significance to older adults. By identifying age differences in variables associated with satisfaction with life, more effective efforts can be made to promote physical and psychological well-being in late adulthood.

Adaptation, Psychological↗

An overview of technological resources used in rehabilitation research with people with severe/profound and multiple disabilities.

PURPOSE: This paper provides an outline of technological resources used in rehabilitation research with persons with severe/profound and multiple disabilities, and discusses the practicality of such resources. METHOD: Research articles published during the last 8 years (1993-2000) are considered. With regard to each of the technological resources used in the articles (i.e. microswitches, speech output devices, computer-aided instruction systems, audio recording systems, orientation systems, mobile robot, and SIBIS), accessibility, cost and implementation issues are examined. RESULTS AND CONCLUSIONS: Some technological resources are easily accessible and affordable (i.e. microswitches, speech output devices, audio-recording systems and SIBIS). Other resources are still at the prototype level (i.e. computer-aided instruction systems, orientation systems and robot) and are much more complex and costly. In spite of this, the latter resources might still have an important role in daily contexts.

Communication Devices for People with Disabilities↗

A search tool based on 'encapsulated' MeSH thesaurus to retrieve quality health resources on the internet.

In the year 2001, the Internet has become a major source of health information for the health professional and the Netizen. The objective of Doc' CISMeF (D'C) was to create a powerful generic search tool based on a structured information model which 'encapsulates' the MeSH thesaurus to index and retrieve quality health resources on the Internet. To index resources, D'C uses four sections in its information model: 'meta-term', keyword, subheading, and resource type. Two search options are available: simple and advanced. The simple search requires the end-user to input a single term or expression. If this term belongs to the D'C information structure model, it will be exploded. If not, a full-text search is performed. In the advanced search, complex searches are possible combining Boolean operators with meta-terms, keywords, subheadings and resource types. D'C uses two standard tools for organising information: the MeSH thesaurus and the Dublin Core metadata format. Resources included in D'C are described according to the following elements: title, author or creator, subject and keywords, description, publishers, date, resource type, format, identifier, and language.

Abstracting and Indexing↗

Stoichiometrically explicit competition between grazers: species replacement, coexistence, and priority effects along resource supply gradients.

Assuming key trade-offs among interactors, several models (resource ratio, keystone predation, intraguild predation) predict changes in species composition over resource supply gradients. Ecological stoichiometry could also predict compositional shifts of grazers over gradients of nutrient and light supply through a mechanism involving (mis)matches between elemental body composition of grazers and plants. This hypothesis is explored here using a suite of two-grazer, one-plant models that incorporate three key components: plant production depends on light and nutrients, nutrient content of plants can vary, and homeostatic grazers can be carbon or nutrient limited. The results from this suite closely resemble the classical resource ratio model describing plant competition for two resources. Here, the models predict shifts of grazer composition along resource supply gradients if species trade off competitive abilities for plant carbon and nutrients. Given this trade-off, superior nutrient competitors should dominate low nutrient environments, and superior carbon competitors should dominate high nutrient environments. At intermediate nutrient supply, species can coexist at a stable equilibrium, or alternative stable states emerge, depending on how grazers impact their resources. These results depend on food web architecture, however. For instance, predators can alter or reduce possibilities for stoichiometry-mediated coexistence of grazers.

Animals↗

A critical review of twenty years' use of the resource-ratio theory.

A model of species interactions based on their use of shared resources was proposed in 1972 by Robert MacArthur and later expanded in an article (1980) and a book (1982) by David Tilman. This "resource-ratio theory" has been used to make a number of testable predictions about competition and community patterns. We reviewed 1,333 papers that cite Tilman's two publications to determine whether predictions of the resource-ratio theory have been adequately tested and to summarize their general conclusions. Most of the citations do not directly test the theory: only 26 studies provide well-designed tests of one or more predictions, resulting in 42 individual tests of predictions. Most of these tests were conducted in the laboratory or experimental microcosms and used primary producers in freshwater systems. Overall, the predictions of the resource-ratio theory were supported 75% of the time. One of the primary predictions of the model, that species dominance varies with the ratio of resource availabilities, was supported by 13 of 16 tests, but most other predictions have been insufficiently tested. We suggest that more experimental work in a variety of natural systems is seriously needed, especially studies designed to test predictions related to resource supply and consumption rates.

Animals↗

Effects of resource heterogeneity on nitrogen translocation within clonal fragments of Sasa palmata: an isotopic (15N) assessment.

BACKGROUND AND AIMS: Clonal fragments of the rhizomatous dwarf bamboo Sasa palmata, which widely predominates in temperate regions of Japan, were grown under heterogeneous resource conditions such as gap understories or nutrient-patchy grassland. Clonal fragments develop multiple ramets with long rhizomes and appear to be physiologically integrated by the translocation of assimilates. The glasshouse experiment reported here was designed to clarify the mechanisms of physiological integration of nitrogen more precisely. METHODS: To assess how resource conditions influence the amount of nitrogen translocation, and which organ acts as the strongest sink, two experiments were conducted that traced movement of 15N label between interconnected pairs of ramets to compare homogeneous and heterogeneous light and soil nitrogen conditions. KEY RESULTS: The amount of 15N translocated to leaves was between 9% and 11% greater in high-N and high-light ramets in the heterogeneous compared with homogeneous treatments. Under heterogeneous soil nitrogen conditions, translocation increased from individual ramets in resource-rich patches to ramets in resource-poor patches, while the reverse was true under heterogeneous light environments, reflecting differences in the positions of leaves that act as the strongest sinks. Neither the mass increments nor the total mass of clonal fragments was significantly affected by heterogeneity of either light or nutrients, possibly because the experimental period was too short for differences to manifest themselves. CONCLUSIONS: This study clearly demonstrated that nitrogen is readily translocated between ramets, particularly under heterogeneous resource conditions. The translocation patterns were governed by functional 'division of labour' mechanisms that resulted in net nitrogen movement from understory sites to gaps, thereby enhancing the carbon acquisition of the whole fragment. Thus, physiological integration may provide benefits for S. palmata when it is growing under heterogeneous conditions in which there are deficits of certain environmental resources.

Data Interpretation, Statistical↗

Men's self-assessed personal health resources: approaching patients' strong points in general practice.

OBJECTIVE: To explore resource-oriented, gender-sensitive approaches in general practice by identifying what men perceive to be their personal health resources. METHODS: A key question was developed to invite men to tell their GPs about personal health resources during ordinary visits. The answers of 39 consecutive male patients (aged 19-84 years) visiting two female GPs were audio taped and analysed, qualitatively inspired by Giorgi's phenomenological approach, supported by theories on salutogenesis, patient-centredness and gender perspectives. The main outcome measures were personal qualities and strategies considered by men to be their health resources. RESULTS: Men considered that the following were personal health resources: optimism, good self-esteem, job satisfaction, ability to cope with stress at work, leisure activities and relaxation with friends producing energy, and fitness and lifestyle activities. CONCLUSION: A key question can give a doctor access to men's thoughts about their strong points. Self-assessed personal health resources can be identified and mobilized by the GP and support a salutogenic approach, which contrasts with the tendency of contemporary medical practice to focus on risk. Asking people about their own ideas may reveal that coping patterns are more complex than reflected in prevailing research.

Adaptation, Psychological↗

An approach to estimating human resource requirements to achieve the Millennium Development Goals.

In the context of the Millennium Development Goals, human resources represent the most critical constraint in achieving the targets. Therefore, it is important for health planners and decision-makers to identify what are the human resources required to meet those targets. Planning the human resources for health is a complex process. It needs to consider both the technical aspects related to estimating the number, skills and distribution of health personnel for meeting population health needs, and the political implications, values and choices that health policy- and decision-makers need to make within given resources limitations. After presenting an overview of the various methods for planning human resources for health, with their advantages and limitations, this paper proposes a methodological approach to estimating the requirements of human resources to achieve the goals set forth by the Millennium Declaration. The method builds on the service-target approach and functional job analysis.

Global Health↗

A full review of online education resources available on antifungal stewardship.

BACKGROUND AND OBJECTIVES: Antifungal resistance represents an increasing global threat, driven by the rising burden of fungal disease. Antifungal stewardship (AFS) is a critical component of broader antimicrobial resistance (AMR) efforts, but education in this area remains less established than antibacterial stewardship initiatives. The scope and characteristics of the current landscape of online AFS resources have not yet been systematically described. To identify and evaluate online educational resources focused on fungal disease management and AFS, and assess their accessibility, format, educational design and implementation focus. METHODS: A structured search of internet search engines, distribution platforms and organizational websites was conducted to identify English-language web-based resources related to fungal disease management and stewardship. Resources were evaluated using predefined criteria including access model, format, length, educational design, interactivity and AFS content. An overall educational value score (1-10) was assigned. RESULTS: Twenty-three educational resources were identified. Most were delivered as online unfacilitated courses (11, 48%) and were short (<4&#x2005;h) (12, 52%). Most focused on guidelines and syndromic management (18, 78%) and targeted doctors and/or nurses/midwives (22, 96%). Limited interactivity was reported in nine (39%) courses. Five courses (22%) had either a substantial or comprehensive focus on AFS. CONCLUSIONS: Online AFS educational resources are available and support awareness and knowledge development. However, they remain relatively few in number. Greater emphasis on implementation-focused learning, behaviour change components and broader global representation may enhance their impact.

Journal Article↗

Psychological resources protect health: 5-year survival and immune function among HIV-infected women from four US cities.

OBJECTIVE: Guided by Cognitive Adaptation Theory, the aim was to determine whether psychological resources (positive affect, positive expectancy regarding health outcomes, finding meaning in challenging circumstances) protect against HIV-related mortality and decline in CD4 lymphocyte counts among women with HIV. DESIGN: The HIV Epidemiologic Research Study, a longitudinal prospective cohort study, with semi-annual interview, physical examination and laboratory assays. METHODS: A total of 773 HIV-seropositive women aged 16 to 55 years were recruited from four academic medical centers in Baltimore, Maryland; Bronx, New York; Providence, Rhode Island; and Detroit, Michigan. Semi-annually for up to 5 years, the women were interviewed, underwent physical examination, medical record abstraction, and venipuncture. Primary outcomes for these analyses included HIV-related mortality and CD4 cell count slope decline over 5 years. RESULTS: Psychological resources were inversely associated with HIV-related mortality and time to death, beyond the effects of potential confounding variables such as clinical status (e.g., HIV viral load, symptoms, antiretroviral therapy), sociodemographic characteristics (e.g. age, race), and depression at study entry (P < 0.05). Psychological resources also were inversely associated with CD4+ cell count decline (P < 0.01), serving as a possible mechanism linking resources to mortality. CONCLUSIONS: Psychological resources may protect against HIV-related mortality and immune system decline. Findings have implications for understanding individual variability in HIV disease progression. Moreover, because psychological resources are potentially amenable to change, results can be applied to clinical interventions aimed at improving the health of women with HIV.

Adult↗

Resource use for total and supracervical hysterectomies: results of a randomized trial.

OBJECTIVE: Hysterectomy is the most common major surgical procedure performed in the United States for nonobstetric reasons. Although most hysterectomies include removal of the cervix, the rate of supracervical procedures has increased in recent years. To provide evidence about the outcomes of both types of hysterectomy, we conducted a randomized clinical trial of total (TAH) or supracervical (SCH) hysterectomy (the "TOSH" trial). We report here an analysis of 24-month resource use by patients in this trial. METHODS: A randomized controlled trial was performed at 3 clinical centers to compare resources used by 120 patients who received a total or supracervical abdominal hysterectomy. Service use during a 24-month follow-up period was identified from medical and billing records and patient reports. Each service used was assigned a relative value, which was then converted into 2002 U.S. dollars. RESULTS: Overall resource use was similar in the 2 study groups in the first 12 months after randomization (TAH 5,870 US dollars; SCH 6,018 US dollars; 95% confidence interval for difference -960 US dollars, 1,255 US dollars; P <.79) and for the full 24 months (TAH 6,448 US dollars; SCH 7,479 US dollars; 95% confidence interval for difference -533 US dollars, 2,616 US dollars; P <.20). In exploratory multivariable analyses, resource use was significantly associated with baseline body mass index greater than or equal to 35 kg/m(2) (8,440 US dollars versus 6,398 US dollars, P =.02) and heavy bleeding (7,550 US dollars versus 5,368 US dollars, P =.02). CONCLUSION: We conclude that the use of medical care resources over a 24-month period is comparable for total and supracervical hysterectomy. The association of a woman's weight and bleeding pattern with subsequent resource use requires further investigation.

Adult↗

Lifetime reproductive success and density-dependent, multi-variable resource selection.

Individuals are predicted to maximize lifetime reproductive success (LRS) through selective use of resources; however, a wide range of ecological and social processes may prevent individuals from always using the highest-quality resources available. Resource selection functions (RSFs) estimate the relative amount of time an individual spends using a resource as a function of the proportional availability of that resource. We quantified the association between LRS and coefficients of individual-based RSFs describing lifetime resource selection for 267 female red deer (Cervus elaphus) of the Isle of Rum, Scotland, from 1970 to 2001. LRS was significantly related to first- and second-order effects of selection for Agrostis/Festuca grassland and proximity to the sea coast (quality of forage within Agrostis/Festuca grassland was highest nearest the coast (ratio of short:long grassland)). The benefits of selecting for quality in Agrostis/Festuca grassland, however, traded-off with increases in LRS gained by avoiding conspecific density. LRS was inversely associated with local density, which was highest along the coast, and reproductive benefits of selecting Agrostis/Festuca grassland diminished with increasing density. We discuss the relevance of these results to our understanding of the spatial distribution of red deer abundance, and potential applications of our approach to evolutionary and applied ecology.

Agrostis↗

The importance of the ontogenetic niche in resource-associated divergence: evidence from a generalist grasshopper.

Geographic variation in resource use can produce locally adapted populations that exhibit genetic and phenotypic divergence. In the bird-winged grasshopper (Schistocerca emarginata = [lineata]), we investigate whether genetic data exist in accordance with geographic variation in resource (host) use and coloration. In Texas, juvenile grasshoppers feed almost exclusively on one of two host plants, Rubus trivialis (Rosaceae) or Ptelea trifoliata (Rutaceae), whereas adults of both forms are dietary generalists and consume many plants from unrelated families. Along with differences in juvenile feeding, differences in a density-dependent color polyphenism are concordant with genetic (mitochondrial DNA) variation among eight populations of the bird-winged grasshopper. Forms feeding on R. trivialis and those feeding on P. trifoliata represent monophyletic lineages according to phylogenetic analysis and maximum-likelihood tests of two alternative phylogeographic hypotheses for geographic variation in host use. Character-state optimization of host-plant acceptability on a phylogeny containing S. emarginata and outgroup taxa indicates that populations consuming R. trivialis gave rise to populations consuming P. trifoliata. Juvenile grasshoppers that consume P. trifoliata acquire deterrence against predation, suggesting that enemy-free space facilitated this host shift. In extant populations, adaptations stemming from alternative resource use during ontogeny present possible barriers to gene exchange. This study represents the first demonstration of resource-associated divergence in an otherwise generalist insect that exhibits temporal variation in resource use, characterized as developmental changes in host specialization. Our findings suggest that exploitation of different resources may have unexplored significance for generalist species that compartmentalize specialization to particular life stages.

Amino Acid Sequence↗

Breast cancer in limited-resource countries: health care systems and public policy.

As the largest cancer killer of women around the globe, breast cancer adversely impacts countries at all levels of economic development. Despite major advances in the early detection, diagnosis, and treatment of breast cancer, health care ministries face multitiered challenges to create and support health care programs that can improve breast cancer outcomes. In addition to the financial and organizational problems inherent in any health care system, breast health programs are hindered by a lack of recognition of cancer as a public health priority, trained health care personnel shortages and migration, public and health care provider educational deficits, and social barriers that impede patient entry into early detection and cancer treatment programs. No perfect health care system exists, even in the wealthiest countries. Based on inevitable economic and practical constraints, all health care systems are compelled to make trade-offs among four factors: access to care, scope of service, quality of care, and cost containment. Given these trade-offs, guidelines can define stratified approaches by which economically realistic incremental improvements can be sequentially implemented within the context of resource constraints to improve breast health care. Disease-specific "vertical" programs warrant "horizontal" integration with existing health care systems in limited-resource countries. The Breast Health Global Initiative (BHGI) Health Care Systems and Public Policy Panel defined a stratified framework outlining recommended breast health care interventions for each of four incremental levels of resources (basic, limited, enhanced, and maximal). Reallocation of existing resources and integration of a breast health care program with existing programs and infrastructure can potentially improve outcomes in a cost-sensitive manner. This adaptable framework can be used as a tool by policymakers for program planning and research design to make best use of available resources to improve breast health care in a given limited-resource setting.

Breast Neoplasms↗

Pupillary responses index cognitive resource limitations.

Cognitive task-evoked pupillary responses reliably index information-processing loads. However, previous studies have reported inconsistent findings regarding the nature of the pupillary response when processing demands approach or exceed available processing resources. This condition was examined in 22 normal undergraduates by using pupillometric recordings during a digit span recall task, with 5 (low load), 9 (moderate load), and 13 (excessive load) digits per string. Pupillary responses increased systematically with increased processing load (to-be-recalled digits) until the limit of available resources (memory capacity of 7 +/- 2 digits), when they reached asymptote and then declined with resource overload (> 9 digits). These findings suggest that pupillary responses increase systematically with increased processing demands that are below resource limits, change little during active processing at or near resource limits, and begin to decline when processing demands exceed available resources.

Adult↗

The UK's SMARTAL Project: St MARTin's College health students Access to Learning resources whilst on placement.

BACKGROUND: St Martin's College pre-registration health students spend up to half their course on periods of placement, during which times they need to be able to access learning resources. The project aimed to replicate the Health and Education Northumbria Students Access to Learning resources (HENSAL) project. OBJECTIVE: To look at patterns of use and access to learning resources for health students on placement. METHODS: Questionnaires were distributed to students who had recently returned from a placement. Five Practice Placement Facilitators were interviewed to gain their views. RESULTS: There was a 60% return rate (n = 268) for the questionnaire. Most students thought access to learning resources was important yet these were not always available and varied according to placement type. Students still made regular use of the College library while they were on placement but had some difficulties. Students used electronic resources, tending to access them from home. CONCLUSIONS: The results indicated that there were issues which needed to be addressed by the College's Faculty of Health and Social Care, Library and IT services, the local NHS Trust libraries and the local Strategic Health Authority to improve access to and use of learning resources. The findings proved to be very similar to those of the HENSAL project.

Health Occupations↗

How dentists cope with their job demands and stay engaged: the moderating role of job resources.

This study focuses on job demands, job resources, and work engagement among 1,919 Finnish dentists employed in the public sector. Based on the Job Demands - Resources model, it was first predicted that the inverse relationship between job demands (e.g. workload, physical environment) and work engagement would be weaker when dentists had many resources (e.g. variability in the required professional skills, peer contacts). Second, using the Conservation of Resources theory it was hypothesized that job resources are most beneficial in maintaining work engagement under conditions of high job demands. The data were based on a postal questionnaire with a response rate of 71%. The dentists were split into two random groups in order to cross-validate the results. A set of hierarchical regression analyses resulted in 17 out of 40 significant interactions (40%). Four out of 20 possible interaction effects could be cross-validated showing, for example, that variability in professional skills mitigated the negative effect of qualitative workload on work engagement and, in addition, boosted work engagement when the qualitative workload was high. The main conclusion is that job resources are useful in coping with the high demands in dentistry and help dentists to stay engaged.

Adaptation, Psychological↗