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PubMedDate not supplied

Pasteurella anatipestifer-like bacteria associated with respiratory disease in pigeons.

Two cases of respiratory disease in pigeons are described. The first case involved pneumonia and tracheitis, and the second case involved tracheitis. In both cases, unusual gram-negative, non-fermenting, short rod-shaped bacteria were recovered along with other microorganisms. The bacteria produced small, glistening, gray colonies on blood agar, did not grow on MacConkey agar, were unreactive on several biochemical tests, and resembled Pasteurella anatipestifer. Neither pigeon isolate was distinguished from P. anatipestifer by biochemical tests. However, there were morphologic and growth differences between the pigeon isolates and P. anatipestifer. Furthermore, unlike P. anatipestifer, both pigeon isolates were sensitive to aminoglycoside antibiotics and to polymyxin B. Finally, neither isolate was agglutinated by antisera to 15 serotypes of P. anatipestifer. Diagnosticians, especially those who seldom encounter P. anatipestifer, might have difficulty distinguishing the pigeon isolates from P. anatipestifer because of their close resemblance.

Animals↗
PubMed1977

Naturally occurring respiratory disease in a kennel caused by Bordetella bronchiseptica.

The role of Bordetella bronchiseptica as a primary pathogen in nautrally occurring respiratory disease of dogs has been in question since its original isolation in 1911. A study to determine the incidence of B. bronchiseptica in a closed breeding kennel has revealed that the frequency of such isolations is closely associated with mild respiratory disease characterized by a moist, sometimes productive, cough. Infection with B. bronchiseptica usually occurred shortly after weaning and produced illness which lasted for one to two weeks. The organisms, however, continued to be shed for two to three months, and important factor in maintaining the infection in this kennel. Adult dogs sampled at frequent intervals did not harbor B. bronchiseptica in spite of their almost constant exposure to heavily infected pups; immunity to reinfection, therefore, appeared to develop. The involvement of several known canine respiratory viral agents was excluded by virus isolation and serological techniques. It therefore was concluded that B. bronchiseptica was the primary cause of respiratory disease in this large breeding kennel.

Animals↗
PubMed2006

Preventing paediatric admissions for respiratory disease: a qualitative analysis of the views of health care professionals.

RATIONALE: The number of emergency paediatric admissions is increasing each year. The reasons for this are unclear but may include increasing demand from parents, changes in GP working patterns, and an increase in unnecessary admissions. Respiratory disease is the commonest diagnostic category for emergency admission in childhood. AIMS: To generate hypotheses for reduction in unnecessary admissions for respiratory disease by qualitative analysis of the views of health care professionals, to determine the proportion of preventable admissions as perceived by clinicians, and to assess the modified Paediatric Appropriateness Evaluation Protocol against clinicians judgements of appropriateness of admission. DESIGN: Eight health care professionals analysed clinical data from primary and secondary care for 94 cases that were admitted to an emergency assessment unit and received a hospital discharge diagnosis of respiratory disease. They assessed whether each admission was appropriate, whether it was preventable, and how it might have been prevented. RESULTS: A total of 31% of cases admitted to the assessment unit (29/94) were classified as preventable by the majority of professionals assessing the case. Provision of additional support, monitoring, and observation in the community was cited as a means of prevention in 33/94 cases. There was poor agreement between the modified PAEP and clinicians' assessments of appropriateness of admission (kappa 0.1). CONCLUSIONS: If the agreed views of these experienced doctors and nurses are correct, provision of additional services in the community could be an important means of preventing emergency admissions for respiratory disease. This hypothesis should be tested by further research including the views of families. The study provides further evidence that the modified PAEP may not be valid for use in UK practice. If inappropriate admission rates are to be used to measure effectiveness of services we need to develop an objective measure of appropriateness valid for use in the UK.

Adolescent↗
PubMed1986

Respiratory disease in animal house workers.

A cross-sectional survey was made to determine the prevalence of respiratory disorders, and the association between symptoms and workplace exposure, in 90 animal-house workers (AHW) and 100 controls (C) without occupational exposure to laboratory animals. Each subject provided a detailed history and serum for radioimmunoassays, and underwent: physical examination, skin testing with common inhalant and animal-derived antigens, and pulmonary function studies. Both groups were comparable with respect to age, sex, smoking habits, and atopy. Rhinitis occurred with similar frequency in each group. However, a more frequent occurrence of asthma (p less than 0.05, non-specific infectious respiratory disease (p less than 0.005), and impaired pulmonary functions (p less than 0.001) was found among AHW. An atopic background was a predisposing factor for the development of laboratory-animal-related respiratory symptoms. These findings imply an increased vulnerability to respiratory disease related to workplace exposure to laboratory animals in atopic individuals.

Adult↗
PubMedDate not supplied

[Respiratory diseases in poultry caused by viruses--occurrence and diagnosis (author's transl)].

The highly intensive conditions, that economic necessity has forced upon the poultry industry, have resulted in strongly changed environmental conditions and management which combined with the use of a constantly increasing number of live vaccines has highly complicated clearing up the etiology in diseased flocks. This is true not least as far as respiratory diseases concerns, which thereby often run an atypical course. A review, however, not complete, is given of the occurrence and diagnostic procedures in respiratory diseases caused by viruses, the greatest importance attached to infections caused by adeno- and infectious bronchitis virus.

Animals↗
PubMed1980

[Vaccination of cattle against respiratory disease caused by virus infection (author's transl)].

Studies on the epizootiology of respiratory viruses in herds of cattle showed that infection by bovine respiratory syncytial (BRS) virus was a major cause of bovine respiratory disease in calves. Moreover, of IBR virus infection associated with respiratory symptoms were observed in the Netherlands since the Spring of 1974. Outbreaks of IBR virus infections occur throughout the Netherlands today. Initially, outbreaks ran a course marked by the typical symptoms of haemorhagic rhinitis, observed particularly in cows. Today, IBR virus infections have become enzootic on several farms, the majority of infections in young cattle being accompanied by respiratory symptoms that are identified as being due to IBR virus infection. Other virus infections that may cause respiratory disease, parainfluenza virus 3, adeno viruses and bovine virus diarrhoea (BVD) virus, were found to be enzootic in most herds in the Netherlands. However, there is no definite correlation between the occurrence of these infections and clinical symptoms. The use of vaccines against these virus infections is not advisable in the present situation. A vaccine against BRS virus infections is commerically available. Immunization by this vaccine against the pulmonary symptoms of BRS virus infection should be verified by a field trial. Unvaccinated control groups of calves should be included. In the experience of the present author, the immunity produced by this vaccine cannot prevent infection by the field strain of BRS virus. Postvaccination reactions were observed within seven days after vaccination with this vaccine in some cases. These were attributable to non-cytopathogenic strains of BVD virus, contaminating some batches of this commerical vaccine.

Animals↗
PubMed1990

Long-term exposure to cement dust and later hospitalization due to respiratory disease.

The relationship between exposure to cement dust in a Portland cement factory and later hospitalization due to respiratory disease and in particular chronic obstructive lung disease (COLD) was examined in a cohort initially examined in 1974. A total of 546 men with different lengths of employment in the cement factory were compared with 857 randomly sampled men of the same age from the same geographical area. Information on hospitalization was obtained from a nationwide register administered by the Danish National Board of Health. During a 9-year, 8-month period, 7.8% of the total population studied had been admitted to hospital at least once because of respiratory disease and 4.3% had been admitted because of COLD. Cement workers had no increased rates of hospitalization when compared with other blue collar workers from the random sample or the whole random sample. A vague tendency towards increasing rates of hospitalization due to COLD with increasing duration of exposure to cement dust up to 30 years was found. Given at least one hospitalization, exposure to cement dust was not related to the accumulated number of days in hospital in the observation period. We conclude that long-term exposure to cement dust does not lead to higher morbidity of severe respiratory disease than other types of blue collar work.

Aged↗
PubMed2006

Association between air pollution and general practitioner visits for respiratory diseases in Hong Kong.

BACKGROUND: Few studies have explored the relation between air pollution and general practitioner (GP) consultations in Asia. Clinic attendance data from a network of GPs were studied, and the relationship between daily GP consultations for upper respiratory tract infections (URTI) and non-URTI respiratory diseases and daily air pollutant concentrations measured in their respective districts was examined. METHODS: A time series study was performed in 2000-2002 using data on daily patient consultations in 13 GP clinics distributed over eight districts. A Poisson regression model was constructed using the generalised additive model approach for each GP clinic, and associations with daily numbers of first visits for URTI were sought for daily concentrations of the following air pollutants: SO(2), NO(2), O(3), PM(10,) and PM(2.5). A summary relative risk of first visits to the GP for URTI per unit increase in concentration for each air pollutant was derived using a random effect model. First visits for non-URTI respiratory diseases were analysed in three GP clinics. RESULTS: Significant associations were observed between first visits for URTI and an increase in the concentrations of NO(2), O(3), PM(10), and PM(2.5). The excess risk was highest for NO(2) (3.0%), followed by O(3) (2.5%), PM(2.5) (2.1%), and PM(10) (2.0%). Similar associations with these air pollutants were found for non-URTI respiratory diseases. CONCLUSIONS: These results provide further evidence that air pollution contributes to GP visits for URTI and non-URTI respiratory diseases in the community.

Air Pollution↗
PubMed1998

Body height and weight and respiratory diseases in skeletal Class II/1 orthodontic patients.

The aims of this study were to determine if there is an increased incidence of respiratory diseases in patients with Angle Class II/1 skeletal intermaxillary relationship in comparison to eugnathic patients and if there is a difference of body height and weight between them. The sample consisted of 60 eugnathic subjects and 88 subjects with Class II/1. Girls were examined at an age of 6, 7, 8, 10, 13 and 14 and boys at an age of 7, 8, 9, 11, 14 and 15. All subjects underwent an orthodontic and medical examination in these time intervals. Data about their respiratory diseases as well as those about their height and weight were taken from their medical files in school dispensaries and were statistically analyzed. No statistically significant differences with regard to the frequency of respiratory diseases were found between eugnathic subjects and those with Class II/1. In almost all investigated time intervals subjects with Class II/1 were statistically significantly higher than the eugnathic subjects, but only in the 8-years old male group with Class II/1 the subjects were heavier than others. The results of this study suggest that patients with Class II/1 either have a faster growth pattern or belong to an asthenic constitution type.

Adolescent↗
PubMed1991

Absence and labour turnover in a foundry attributable to respiratory disease.

A survey of foundry workers was undertaken to assess the effect of respiratory disease on both absence in the year prior to the survey and labour turnover since a cross-sectional study of respiratory morbidity five years previously. The presence of a wheeze, but not an objective disturbance of airway function, was predictive of absence. Those with respiratory illness, detected in the survey five years previously, were no more likely to have left the foundry than those without such illness. Limited job opportunities may discourage moulders with respiratory disease from leaving the foundry. Absence was not related to cigarette smoking, the presence of bronchial hyperreactivity, or a positive skin test to common allergens. In view of the small number of subjects in this study, studies of larger work populations should be undertaken to further assess the effect of subjective and objective indices of respiratory morbidity on absence and labour turnover.

Absenteeism↗
PubMed2004

Efficacy of danofloxacin in the treatment of respiratory disease in European cattle.

The efficacy of an injectable formulation of danofloxacin (180 mg/ml) in the treatment of naturally occurring bovine respiratory disease was evaluated in field studies on farms in France, Ireland and the United Kingdom. Cattle aged one week to 15 months with clinical respiratory disease were randomly allocated to treatment with 6 mg/kg danofloxacin or 10 mg/kg tilmicosin, administered by a single subcutaneous injection on day 0. A second injection of danofloxacin was administered on day 2, only if predefined clinical criteria were met. Mannheimia haemolytica, Pasteurella multocida and Haemophilus somnus were isolated from pretreatment nasopharyngeal swabs taken on all the farms. After the treatment, there was a more rapid improvement in the clinical response of the 178 animals treated with danofloxacin by day 2 (P < 0.01) than in the 90 treated with tilmicosin. For both treatments, there were similar significant (P < 0.001) reductions in the mean rectal temperature and severity of clinical signs of abnormal respiration and depression, on days 4 and 10 compared with day 0; 78.1 per cent of the animals treated with danofloxacin and 78.5 per cent of those treated with tilmicosin completed the studies. Danofloxacin 18 per cent was clinically safe and as effective as tilmicosin in the treatment of bovine respiratory disease.

Animals↗
PubMed2002

Management of childhood diseases during the Byzantine period: III-- respiratory diseases of childhood.

Evidence on herbal, veterinary and chemical substances used in various forms for respiratory problems of childhood such as acute otitis, acute tonsillitis and parotitis was investigated in the Byzantine medical treatizes, from the 4th to the 15th century ad. The problem of asthma in childhood was well known during the Byzantine period. Despite the existent Hippocratic tradition, the physicians of the times developed their own methods of treatment. The texts of Antyllus, Orivasios from Pergamos, Aetius of Amida, Alexander of Tralles, Paulus Aeginitis, Theophanis Nonnos and others, strongly suggest influences from ancient Greek and Roman medicine, but at the same time indicate an original medical thought.

Asthma↗
PubMed1973

Use of excess mortality from respiratory diseases in the study of influenza.

Since 1970, WHO has conducted a collaborative study on the use of "excess mortality" from respiratory diseases (that is, the number of deaths actually recorded in excess of the number expected on the basis of past seasonal experience) in order to assess in 13 different countries the severity of influenza epidemics. The use of computer-produced seasonal expected and actual curves permits quick visual assessment of influenza activity in any one country, as well as comparisons between different countries. The study demonstrates that an excess in the observed over the expected number of total deaths does not necessarily indicate an excess in deaths from influenza, and it is therefore limited, at least for the present time, to deaths from respiratory disease. It provides a week-to-week record of deaths from acute respiratory disease in countries where weekly returns are available and a retrospective analysis of the disease pattern in the collaborating countries. This study will be continued for a number of years and, apart from its value to the individual countries, should provide useful comparisons between countries with different climates.

Asia↗
PubMed1998

Civilian outbreak of adenovirus acute respiratory disease--South Dakota, 1997.

Adenoviruses are human pathogens that commonly infect the respiratory and gastrointestinal tracts. Adenovirus infections are endemic, particularly among children, but also may cause epidemics of pharyngoconjunctival fever, keratoconjunctivitis, gastroenteritis, and acute respiratory disease (ARD) among military trainees. Outbreaks of ARD among adults in the civilian sector are rare. In March 1997, an outbreak of acute respiratory disease (ARD) caused by adenovirus serotype 11 occurred among students at a job training facility in South Dakota. This report summarizes the epidemiologic and clinical features of this outbreak and discusses the change in availability of adenovirus vaccines for military use.

Acute Disease↗
PubMed2006

[Differences in small area prevalence of respiratory diseases in children: challenges of an investigation initiated by parents].

OBJECTIVE: The aim of our study was to assess the prevalence of respiratory diseases in children living in a rural area in Bavaria in a systematic and standardised way to clarify whether a disease cluster exists. Reports from a parents' initiative claiming an increase of diseased children and assuming an association with air pollution due to nearby industrial sources and heavy traffic were the reason for the study. METHODS: Parents of all children living in small towns specified by the parents' initiative as affected region (central area) and parents of those children aged 6-7 or 13-14 years living in adjacent areas (control area) were asked to complete a written questionnaire. In bivariate analysis, differences in prevalences between the central area and the control area were assessed by the chi (2) test. In multivariate analysis, confounder-adjusted odds ratios with 95 % confidence intervals were calculated by logistic regression. In addition, generalized linear mixed models were used to control for potential clusters in families. RESULTS: The response rate was rather low (total 46 %, central area 53 %, control area 34 %). The study population comprised 121 girls and 141 boys. There was a pattern of increased prevalences of cough, wheeze and respiratory diseases caused by infections in children living in the central area compared to the control area. However, statistical significance was rarely observed. No systematic differences were observed for the prevalence of allergic rhinitis and atopic dermatitis. Selection bias due to varying response rates in the central versus the control area and information bias introduced by the preceding intensive public discussion could not be excluded. The comparison of prevalences detected in the small area with published data from other epidemiological studies in Germany did not indicate a systematically increased prevalence of respiratory symptoms or physician-diagnosed respiratory diseases in children from the whole area as well as in children from the central area only. CONCLUSION: This study exemplifies the challenges of small area investigations initiated by the residential community to clarify an assumed disease cluster caused by environmental pollution. The prior comparison of small area prevalence data with results of other epidemiological studies aids the decision making as to whether a detailed study with comprehensive assessment of individual exposure is justifiable.

Adolescent↗
PubMedDate not supplied

The respiratory disease questionnaire: use of a self-administered version.

A re-designed and simplified respiratory disease questionnaire was self-completed by 245 coke oven workers who previously were interviewed using the Standardized Medical Research Council/National Heart and Lung Institute form. The self-completion survey yielded significantly greater numbers of positive responses to various questions; nearly twice as many men were classified as having chronic bronchitis based on responses to the self-administered questionnaire. The severity of symptoms correlated with various factors such as the worker's smoking history; family history of lung disease, and job history. We suggest that, when compared with an interview using the British Medical Research Council/National Heart and Lung Institute respiratory disease questionnaire, a simplified, self-completion form may serve as a less expensive, more sensitive, and equally uniform and selective epidemiological tool. Self-completion forms deserve the attention and study previously afforded the interview process.

Adult↗