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PubMed1987

[Peristomal pyoderma gangrenosum in a patient with ulcero-hemorrhagic rectocolitis].

Cutaneous manifestations of chronic ulcerative colitis are numerous and present in 20 p. 100 of the patients. The case of a 49-year old man with peristomal pyoderma gangrenosum (PG) is presented. In November, 1983, one year after the onset of chronic ulcerative colitis, the patient underwent total colectomy. The formation of an ileal reservoir resulted in a pelvic abscess which necessitated right lower ileostomy. Because of severe ulcerations around the stoma, the ileostomy was transferred to the left lower abdomen. Similar inflammatory ulcerations developed, and the diagnosis of pyoderma gangrenosum was made. The patient responded very well to dapsone combined with prednisone for only 6 months. The possibility of PG being an autoimmune condition is discussed, as well as the differential diagnosis. The several therapeutic approaches are summarized. The peristomal localization of PG in this patient suffering from chronic ulcerative colitis seems to be rather unique. No other case has been reported so far, to our knowledge.

Administration, Topical↗
PubMed1987

[Rectocolic tuberculosis. Radiological aspects apropos of 14 cases].

During 11 years, 14 cases of tuberculosis of the colon are radiographied. The clinical findings are not specific and the association with evolutive pulmonary tuberculosis is infrequent (28%). The radiological features are described: ulcerations (4 cases), ulcerations and hypertrophic features (3 cases) and hypertrophic features (7 cases). The involving sites are caecum and ileocecum in 6 cases, ascending colon in 3 cases, transverse colon in 2 cases, descending colon in 2 cases and recto-sigmoid in 2 cases. The differential diagnosis are segmental Crohn colitis and colonic carcinoma. Endoscopic examination with biopsy is a help to the diagnosis, but in 5 cases, it will be deficient. The diagnosis of colonic tuberculosis is setting only by surgical resections in 6 cases (43%) and 4 patients have been treated by medical treatment with success. No relapse appears in operated patients.

Adult↗
PubMedDate not supplied

[Cutaneous symptoms of ulcero-haemorragic rectocolitis and of Crohn's disease (author's transl)].

The association between ulcerative colitis, Crohn's disease and various abnormalities of the skin is reviewed. Erythema nodosum and pyoderma gangrenosum are the most specific external manifestations and thereby the ones of greatest diagnostic value. Erythema multiforme is probably a manifestation of drug hypersensitivity. Many other dermatosis have been observed in association with these gastrointestinal disorders. However, these associations are not statistically significant. A specific "aphtous colitis" may be observed in the course of Behçet's disease.

Colitis, Ulcerative↗