[Fractures of the femur treated with nailing. Comparison of cases operated on in the periods 1946-1959 and 1960-1965. II. Follow-up of about 100 cases treated during the second period].
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A wide variety of agents has been demonstrated to be capable of affecting the fetus in utero. Certain generalizations can be made concerning these teratogens. Two of the most important of these principles are the specificity of the agent and the time during gestation of the exposure. Although noticeable adverse effects are structural malformations, there are numerous functional malformations, such as lower intelligence and poor reproductive outcome, that may follow exposure to these agents. There is some evidence that future behavior may be affected by in utero teratogen exposure; however, this field has been infrequently investigated and no firm conclusions can be drawn.
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