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Results for “Ophthalmodynamometry”

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At least 451 records · Page 25Linked to original sources

Variability of Doppler ophthalmic pressure index with occlusive carotid artery disease.

To evaluate day-to-day variability of Doppler ophthalmic pressure index by means of the ophthalmomanometry-Doppler technique, bilateral ophthalmic artery pressure and indirect systemic blood pressure determinations were repeated within 1 month in 40 patients with clinically stable occlusive carotid disease. No difference in Doppler ophthalmic pressure and calculated pressure index between both days could be demonstrated. The standard deviation of differences in ophthalmic pressure index between first and second day measurements was 0.04. Correlation between bilateral ophthalmic pressure index measurements on both days was high (r = 0.93, n = 80). It is concluded that individual Doppler ophthalmic pressure index must change at least 0.08 before it can be considered significant. In 37 patients with occlusive carotid artery disease (greater than 60% diameter reduction) undergoing 38 endarterectomies, Doppler ophthalmic pressure index was evaluated before and after surgery. Mean +/- SD ipsilateral Doppler ophthalmic pressure index increased from 0.59 +/- 0.07 to 0.71 +/- 0.05 (p less than 0.001) after endarterectomy. In 12 patients with significant bilateral occlusive carotid disease, mean +/- SD contralateral Doppler ophthalmic pressure index increased from 0.54 +/- 0.05 to 0.61 +/- 0.06 (p less than 0.02), whereas contralateral pressure index in patients with unilateral disease showed no change (0.71 vs 0.71) after ipsilateral endarterectomy. These results indicate that carotid endarterectomy not only normalizes ipsilateral Doppler ophthalmic pressure index but also improves contralateral Doppler ophthalmic pressure index provided significant bilateral occlusive carotid disease is present.

Adult↗

Differential effect of ischemia/reperfusion on pigmented and albino rabbit retina.

The purpose of the study was to compare the retinal sensitivity of pigmented and albino rabbits to ischemia/reperfusion-induced electroretinogram (ERG) alterations and optic nerve morphological changes. High intraocular pressure (HIOP) was induced by applying a suction-cup on the eye and a depression with an ophthalmodynamometer. HIOP was maintained for lengths of time (30-75 min). Flash ERGs were recorded in dark-adapted animals for ischemia and 2 h reperfusion periods. Two weeks later, histological examination of the retinas and optic nerves was done. Albino rabbits submitted to 45 min HIOP failed to recover b-wave ERG amplitude after 2 h reperfusion, whereas pigmented animals presented a total ERG recovery even if ischemia was maintained as long as 75 min. Intravenous treatment of albino animals with Lazaroid U74389G led to significant ERG recovery at reperfusion. Histological studies show that pigmented rabbit optic nerves suffered less damage than the albino ones. These results emphasize the role of the pigmentary status of the animals in the retinal sensitivity to ischemia. Neuroprotection afforded by the antioxidant U74389G suggests that ocular pigments could also protect the retinal functional integrity through a free radical scavenging activity.

Albinism, Ocular↗

Measurement of dynamic stereoacuity and global stereopsis.

Quantification of global stereopsis in addition to stereoacuity has been achieved by using dynamic random dot test patterns generated by inexpensive computer controlled integrated electronics. A pilot study revealed marked differences between the responses of a variety of clinically defective and normal subjects.

Adolescent↗