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[Biochemistry of neonatal cord blood following intrapartum glucose and oxytocin infusion].

The effect of intrapartum glucose and oxytocin infusion on the biochemical values of umbilical cord blood including Na, K, Cl, Ca, P, glucose, BUN and osmolality was studied in 246 newborns. The newborns were divided into 4 groups: Group 1 consisted of 162 babies whose mothers did not receive any intravenous infusion. Group 2. 53 babies, Group 3. 16 babies and Group 4.15 babies whose mothers received infusion of oxytocin in glucose (5U/L). The total amounts of infusion were less than 500 ml in Group 2. 500ml in Group 3. 500-1,000 ml in Group 4. Group 3 were delivered with forceps. In comparison with Group 1, the serum K+ in Group 2 and Cl- values in Group 4 were lower while the glucose values were higher in Groups 2, 3 and 4 (highest in Group 3). The other values were not significantly different.

Blood Glucose↗

Diurnal variation in admission to hospital of women in labour.

In women having spontaneous labour or premature rupture of the membranes there is a marked diurnal variation in times of admission to hospital. Analysis of 4755 nulliparous women with single pregnancies in cephalic presentation at term, indicated that they presented in labour or with premature rupture of the membranes nearly twice as frequently during the night as during the evening. The peak hours for delivery were late morning and afternoon. The authors discuss previously published reports of similar findings and of a diurnal variation in maternal hormone levels in humans and experimental animals. The potential clinical importance of this phenomenon is considered.

Circadian Rhythm↗

[Active management of labor in Dublin: what is it 15 years later?].

Every obstetrician, in his readings, must have come across a report of article by K. O'Driscoll, and could not remain indifferent (surprise, incredulity, even anger...) in front of astonishing results: 5% of caesarean sections, 5 to 6% of forceps deliveries, combined with a recruiting worthy of any large university center and creditable neonatal results which are accurately analysed. In view of the difficulty and understanding of the basis of "active management of labor", advocated by this team and described as the main reason of its success, the author tried to understand, while staying in this department, the highlights of its daily obstetrical practice. In this detailed report of the activities of this irish obstetrical team, the author wanted to put the results back in their context and broadly outline the organization of this department and the management of labor, in order to evaluate the significance of the figures reported in numerous international publications and too often not easy to analyse for uninformed readers.

Anesthesia, Obstetrical↗

A labor readiness index (Bishop score) for rhesus monkeys.

A scoring system is presented for quantitative evaluation of labor readiness in macaque monkeys. Cervical position, length, softness and dilation are rated along with fetal head position for a total score of 13. The system is based on experience in evaluating readiness of multiparous rhesus monkeys for labor induction. Guidelines for the examination for use of the score are described.

Animals↗

Interval from rupture of the membranes to delivery and neonatal respiratory adaptation.

The influence of the time interval from rupture of the membranes to delivery on neonatal respiratory adaptation was analysed in a prospective study of all infants born in Göteborg, Sweden in one year. The correlation between the incidence of respiratory disorders and the rupture-delivery interval was analysed in all preterm infants (less than or equal to 36 weeks, n = 240) and in all term infants born by caesarean section (n = 452). A uniform pattern was found for all preterm infants, irrespective of mode of delivery, and for the term infants born by caesarean section. The curve was 'U-shaped' with higher incidence of respiratory diseases in infants born immediately after rupture of the membranes than in those born 3-36 h after membrane rupture. The incidence increased again in infants born greater than 36 h after membrane rupture. The same pattern was found for all kinds of respiratory diseases including idiopathic respiratory distress syndrome. Therefore, there seems to be no advantage in postponing delivery greater than 36 h after rupture of the membranes.

Cesarean Section↗