Krypton 85 inhalation tests versus oxygen saturation studies for detection of left-to-right circulatory shunts.
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A new technique consisting of continuous intraarterial infusion of the ultra-short-lived 81mKr for the study of blood flow in patients with severe peripheral vascular disease is described. With the gamma camera high resolution images and typical time activity curves, reflecting local regional blood flow in the feet, could be obtained under resting conditions during reactive hyperemia and administration of vasodilating drugs. Preliminary promising results of Ketanserin, a new selective serotonin antagonist, in patients with impending gangrene and ulcerations are discussed.
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A recovery-purification system for radioactive Kr was constructed by enclosing an 85Kr testing apparatus with an airtight vessel. Experiments were carried out to examine the recovery rate of leakage Kr and the purity of Kr recovered with the system. The concentration of the leakage Kr in the airtight vessel was decreased to a detection limit of 0.3 ppm by the system. The recovery rate corresponded to 99.976%. The concentration of the Kr recovered was over 99.9908%. It shows that almost 100% of the radioactive Kr leaked out into the airtight vessel could be recovered and the He content in the Kr recovered could be reduced to less than 100 ppm.
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