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PubMed1976

[Effect of climatic exposure and physical activity on plasma cortisol levels and urinary 17-hydroxycorticosteroid excretion in patients with hypertension].

Decrease in arterial pressure, mainly manifested in the first 5-10 days, was established in 111 patients with hypertension disease in functional and initial organic stage in the conditions of moderately high mountain (1870 m above sea level) after 25/20 days of complex climatic treatment including: active motor regimen, sun-air exposure and Pevzner diet No 10. Simultaneously the excretion of 17-hydroxicorticosteroids was increased in daily urine. Suprarenal cortex stimulation is best manifested after the first week and is kept till the end of the treatment. Cortisol plasma level was elevated in 42.7 per cent of the patients with hypertension disease with initial values under 15 mkg/100 ml plasma after three hours moderately severe physical activity, carried out in physiological thermal conditions and was decreased with 25.9 per cent with initial levels over 20 mkg/100 ml plasma. Parallely, 17-hydroxicoricosteroids secretion in urine was decreased as well as the systolic and diastolic arterial pressure.

17-Hydroxycorticosteroids↗