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PubMed1963

Diagnosis of oral oral lesions.

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Glossitis↗

PubMed1991

Histoquantitative study of inflamed tongue mucosa.

A quantitative, semiautomatic analysis of histologic features of the specific inflammatory changes occurring on the dorsum of human tongue was made for 37 tongues. Well-documented histologic differences between clinically normal appearing tongue (control), atrophic, geographic and fissured tongue were shown quantitatively. The epithelium of atrophic tongue was thinner compared to the controls. Reduction of the thickness was due to the shortened or totally missing rete pegs. Epithelium of geographic and fissured tongue showed irregular rete pegs. In fissured tongue heavy inflammation seemed to shorten the rete pegs. In atrophic tongue the connective tissue was thicker compared to the controls. This could be due to mild, chronic inflammation causing loose connective tissue described in atrophic tongue. Muscle cells of geographic tongue appeared to be as in the controls, whereas in atrophic and fissured tongue the uppermost muscle cells were small and separated compared to the controls.

Adult↗

PubMed1964

NICOTINIC ACID ANALOGS: EFFECTS ON RESPONSE OF CHICK EMBRYOS AND HENS TO ORGANOPHOSPHATE TOXICANTS.

Embryonic abnormalities are known to be induced in chick embryos when they are injected with certain organophosphate insecticides prior to incubation. The marked teratogenic effects of Bidrin [3-(dimethoxyphosphinyloxy) N, N-dimethyl-cis-crotonamide] can be alleviated by many analogs of nicotinamide and nicotinamide adenine dinucleotide. Successive hydroxylation and N-dealkylation of Bidrin in the egg are not greatly altered by injection of nicotinamide. The delayed neurotoxicity in adult hens after administering tri-o-cresyl phosphate is also partially relieved by administering certain nicotinamide analogs.

Abnormalities, Drug-Induced↗

PubMed1963