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[Systemic disease caused by the fungus Aspergillus fumigatus in immunocompromised patients].

The authors describe an invasive pulmonary Aspergillus infection in three immunocompromised patients (1x plasmacytoma, 1x autoimmune thrombocytopenia, 1x asthma bronchiale) and draw attention to the possible occurrence of this disease also in subjects without serious neutropenia. The common risk factor in all three patients was corticoid treatment. In immunocompromised patients only early adequate and sufficiently long antimycotic treatment gives hope that the infection will be controlled.

Aged↗

[Clinical variants in the course of a fungal disease caused by a fungus in the genus Paecilomyces].

The data are available on 23 cases of eosinophil-type leukemoid reaction to infection with Paecilomyces fungi treated in 1980-1987. The clinical course presented with high fever on the onset followed by the subfebrile temperature later, symptoms of upper respiratory tract catarrh, enlargement of peripheral lymph nodes, involvement of other organs, 78-84% eosinophilia, leukocytosis at the onset. Upon establishment of accurate diagnosis by specific laboratory tests, the etiopathogenetic treatment was administered. The response was achieved in 94% of the patients.

Adolescent↗

Cutaneous phaeohyphomycosis caused by Alternaria longipes in an immunosuppressed patient.

Alternaria longipes was reported as the agent of a cutaneous infection in a patient with a neoplastic disease. The fungus has not been reported previously as causing disease in humans. It was distinguished by its rather small conidia with smooth or slightly verruculose walls and a pale brown beak which rarely extended into a secondary conidiophore. In vitro inhibitory activities of amphotericin B, ketoconazole, itraconazole, and miconazole were shown.

Alternaria↗