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Assessment of Internet-based tele-medicine in Africa (the RAFT project).

The objectives of this paper on the Réseau Afrique Francophone de Télémédecine (RAFT) project are the evaluation of feasibility, potential, problems and risks of an Internet-based tele-medicine network in developing countries of Africa. The RAFT project was started in Western African countries 5 years ago and has now extended to other regions of Africa as well (i.e. Madagascar, Rwanda). A project for the development of a national tele-medicine network in Mali was initiated in 2001, extended to Mauritania in 2002 and to Morocco in 2003. By 2006, a total of nine countries are connected. The entire technical infrastructure is based on Internet technologies for medical distance learning and tele-consultations. The results are a tele-medicine network that has been in productive use for over 5 years and has enabled various collaboration channels, including North-to-South (from Europe to Africa), South-to-South (within Africa), and South-to-North (from Africa to Europe) distance learning and tele-consultations, plus many personal exchanges between the participating hospitals and Universities. It has also unveiled a set of potential problems: (a) the limited importance of North-to-South collaborations when there are major differences in the available resources or the socio-cultural contexts between the collaborating parties; (b) the risk of an induced digital divide if the periphery of the health system in developing countries is not involved in the development of the network; and (c) the need for the development of local medical content management skills. Particularly point (c) is improved through the collaboration between the various countries as professionals from the medical and the computer science field are sharing courses and resources. Personal exchanges between partners in the project are frequent, and several persons received an education at one of the partner Universities. As conclusion, we can say that the identified risks have to be taken into account when designing large-scale tele-medicine projects in developing countries. These problems can be mitigated by fostering South-South collaboration channels, by the use of satellite-based Internet connectivity in remote areas, the appreciation of local knowledge and its publication on-line. The availability of such an infrastructure also facilitates the development of other projects, courses, and local content creation.

Africa↗

Treatment of persistent pruritus ani in a combined colorectal and dermatological clinic.

BACKGROUND: Pruritus ani is a common and socially embarrassing condition which is often poorly managed. It is often classified as idiopathic where the symptoms are usually transitory or secondary when a more persistent itch is experienced. The aim of this study was to establish the cause of pruritus ani in a group of patients referred to a combined colorectal and dermatological clinic, and to determine the most appropriate treatment. METHODS: Forty consecutive patients with pruritus ani were referred over a 6-month period from either the general practitioner or another hospital consultant to a combined colorectal and dermatological clinic. They were assessed by history, completion of a general health questionnaire, full examination of the skin, digital rectal examination, proctoscopy, sigmoidoscopy and patch testing. Patients were treated according to clinical findings at assessment. RESULTS: Thirty-four patients had a recognizable dermatosis, three had superficial perianal fissuring and three had a normal perineum; two required surgical intervention. Eighteen patients had a positive reaction when patch tested. All patients have shown an improvement or complete resolution of symptoms with treatment. CONCLUSION: This series has shown that the majority of patients presenting with pruritus ani have a dermatosis as the underlying cause of their symptoms and that many of them have developed contact sensitivities to the various topical medications used. These findings suggest that referral to a dermatologist in the first instance may be more appropriate.

Adolescent↗

Fundus imaging and the telemedical management of diabetes.

Diabetes is the major preventable form of blindness among people of working age in the Western world, despite the improvements in laser photocoagulation treatments. It is known that regular glycaemic control and annual retinal screening of people with diabetes can reduce its incidence. Effective treatment needs to be available but also screening methods which are simple to perform and cost-effective should be implemented. It will be important in future to integrate digital images of the fundus into the health records of diabetic patients. Screening programmes for the detection of diabetic retinopathy aided by image-processing software for processing fundus images will save manpower and increase quality. Before this can happen, we need more clinical studies of store-and-forward techniques, so that they can be standardized and their effectiveness established against that of traditional analogue screening.

Diabetic Retinopathy↗

Telemedicine in Western Africa: lessons learned from a pilot project in Mali, perspectives and recommendations.

OBJECTIVE: to evaluate the feasibility, potential and risks of an internet-based telemedicine network in developing countries of Western Africa. METHODS: a project for the development of a national telemedicine network in Mali was initiated in 2001, using internet-based technologies for distance learning and teleconsultations. RESULTS: the telemedicine network has been in productive use for 12 months and has enabled various collaboration channels, including North-South, South-South, and South-North distance learning and teleconsultations. It also unveiled a set of potential problems: a) limited pertinence of North-South collaborations when there are major differences in available resources or socio-cultural contexts between the collaborating parties; b) risk of induced digital divide if the periphery of the health system is not involved in the development of the network, and c) need for the development of local medical contents management skills. CONCLUSION: the identified risks must be taken into account when designing large-scale telemedicine projects in developing countries and can be mitigated by the fostering of South-South collaboration channels, the use of satellite-based internet connectivity in remote areas, and the valorization of local knowledge and its publication on-line.

Africa, Western↗

Measurement of fatigue following 18 msw dry chamber dives breathing air or enriched air nitrox.

Many divers report less fatigue following diving breathing oxygen rich N2-O2 mixtures compared with breathing air. In this double blinded, randomized controlled study 11 divers breathed either air or Enriched Air Nitrox 36% (oxygen 36%, nitrogen 64%) during an 18 msw (281 kPa(a)) dry chamber dive for a bottom time of 40 minutes. Two periods of exercise were performed during the dive. Divers were assessed before and after each dive using the Multidimensional Fatigue Inventory-20, a visual analogue scale, Digit Span Tests, Stroop Tests, and Divers Health Survey (DHS). Diving to 18m produced no measurable difference in fatigue, attention levels, ability to concentrate or DHS scores, following dives using either breathing gas.

Adult↗

Environmental tobacco smoke and lung cancer in nonsmoking women. A multicenter study.

OBJECTIVE: To determine the relative risk (RR) of lung cancer in lifetime never smokers associated with environmental tobacco smoke (ETS) exposure. DESIGN: Multicenter population-based case-control study. SETTING: Five metropolitan areas in the United States: Atlanta, Ga, Houston, Tex, Los Angeles, Calif, New Orleans, La, and the San Francisco Bay Area, Calif. PATIENTS OR OTHER PARTICIPANTS: Female lifetime never smokers: 653 cases with histologically confirmed lung cancer and 1253 controls selected by random digit dialing and random sampling from the Health Care Financing Administration files for women aged 65 years and older. MAIN OUTCOME MEASURE: The RR of lung cancer, estimated by adjusted odds ratio (OR) with 95% confidence interval (CI), associated with ETS exposure. RESULTS: Tobacco use by spouse(s) was associated with a 30% excess risk of lung cancer: all types of primary lung carcinoma (adjusted OR = 1.29; P < .05), pulmonary adenocarcinoma (adjusted OR = 1.28; P < .05), and other primary carcinomas of the lung (adjusted OR = 1.37; P = .18). An increasing RR of lung cancer was observed with increasing pack-years of spousal ETS exposure (trend P = .03), such that an 80% excess risk of lung cancer was observed for subjects with 80 or more pack-years of exposure from a spouse (adjusted OR = 1.79; 95% CI = 0.99 to 3.25). The excess risk of lung cancer among women ever exposed to ETS during adult life in the household was 24%; in the workplace, 39%; and in social settings, 50%. When these sources were considered jointly, an increasing risk of lung cancer with increasing duration of exposure was observed (trend P = .001). At the highest level of exposure, there was a 75% increased risk. No significant association was found between exposure during childhood to household ETS exposure from mother, father, or other household members; however, women who were exposed during childhood had higher RRs associated with adult-life ETS exposures than women with no childhood exposure. At the highest level of adult smoke-years of exposure, the ORs for women with and without childhood exposures were 3.25 (95% CI, 2.42 to 7.46) and 1.77 (95% CI, 0.98 to 3.19), respectively. CONCLUSION: Exposure to ETS during adult life increases risk of lung cancer in lifetime nonsmokers.

Aged↗

Clinical data exchange standards and vocabularies for messages.

Motivation for the creation of electronic data interchange (message) standards is discussed. The ISO Open Systems Interface model is described. Clinical information models, message syntax and structure, and the need for a standardized coded vocabulary are explained. The HIPAA legislation and subsequent HHS transaction recommendations are reviewed. The history and mission statements of six of the most popular message development organizations (MDOs) are summarized, and the data exchange standards developed by these organizations are listed. The organizations described include Health Level Seven (HL7), American Standards for Testing and Materials (ASTM) E31, Digital Image Communication in Medicine (DICOM), European Committee for Standardization (Comité Européen de Normalisation), Technical Committee for Health Informatics (CEN/TC 251), the National Council for Prescription Drug Programs (NCPDP), and Accredited Standards Committee X12 Insurance Subcommittee (X12N). The locations of Internet web sites for the six organizations are provided as resources for further information.

Computer Communication Networks↗

[Psychological impact of the new digital media].

This review article starts from the hypothesis that the new digital media's impact on people's mental health, which in professional and private everyday life has become increasingly frequent and intense, is widely underestimated. The disturbances associated with media exposure, which have been already described and examined, are presented and discussed, while classifying them in three groups of disorders, namely dissocial, dissociative and impulse control disorders. In a second step, psychotherapeutic and psychiatric applications of the digital media are presented, especially, psychometric and neuropsychological testing, distribution of information and behavioral therapeutic tools. The positive and negative effects of the internet and cyberspace are applied to the multicausal understanding of the genesis and therapy of mental disturbances. Against this background, the opinion is held, that the paradigmatic medialization of the world has to be taken seriously and actively approached as a psycho-ecological factor with psychosocial, psychopathogenic and also neuroplastic effects. Therefore, also a psychiatric approach is needed to establish both research on media-associated disorders including their therapy and the development of quality standards in the therapeutic use of the Internet and Cyberspace.

Antisocial Personality Disorder↗

Physician extenders: who is using them?

BACKGROUND: Nurse practitioners and physician assistants (physician extenders) are playing an increased role in medical care. The purpose of this research was to determine the proportion of adults who have received health care from physician extenders. METHODS: This study used the subject population of the 1990 Kentucky Health Survey, a probability survey of all households in Kentucky. Study personnel contacted subjects using random digit telephone dialing. Subjects were then interviewed to ascertain whether subjects had received health care from physician extenders and whether they were satisfied with that care. RESULTS: Of 687 participating subjects, 25% had received care from physician extenders during the previous two years, primarily for minor problems and routine checkups. More than 90% of these subjects reported satisfaction with the care they received. Users of physician extenders did not differ from nonusers with respect to income, education, insurance status, self-assessment of health status, or rural versus urban location. Men used physician extenders more frequently than women. CONCLUSIONS: A substantial proportion of the population has used physician extenders. Patient satisfaction with physician extenders is high. Use of physician extenders may be an effective strategy for improving delivery of primary care.

Adult↗

Global reach and sustained engagement of a structured digital education program in medical mycology: an observational analysis of the 2025 ESCMID-EFISG webinar series.

OBJECTIVES: Evaluate the 2025 European Society of Clinical Microbiology and Infectious Diseases-European Fungal Infection Study Group webinar series to assess digital education as a scalable, equitable model for global professional development in medical mycology. METHODS: This observational study analyzed Zoom metadata across 17 webinars (January-December 2025). Metrics included registration, unique viewers, peak concurrent views, attendance rate, and duration. RESULTS: The series recorded 4631 registrations and 1372 unique participants. Median live attendance was 199 (interquartile range [IQR] 138-269), with a 39.3% attendance rate (IQR 33.7-47.5%) and peak concurrent viewership of 165 (IQR 106-229). Median session duration was 108 minutes. Webinars engaged a median of 60 countries (range 26-89) simultaneously, spanning 128 countries globally. Faculty comprised 67 unique experts from 23 countries with balanced gender representation (52.8% men, 47.2% women), of whom 16.4% (n = 11/67) were affiliated with institutions in low- and middle-income countries. CONCLUSION: Structured digital programs achieve wide global reach and sustained engagement. Strong participation in long-form sessions supports implementing Continuing Medical Education accreditation and unrestricted on-demand access to enhance global health equity.

Antimicrobial resistance↗

Image processing for enhanced observer agreement in the evaluation of periapical bone changes.

AIM: The aim of the present study was to evaluate the effect of root canal treatment on periapical lesions by conventional and subtracted digital radiographic images of clinical cases. METHODOLOGY: Eleven patients who exhibited clinical or radiological signs of periapical pathology received root canal treatment. Periapical radiographs were obtained immediately postoperatively and recall radiographs at intervals of 3, 6, 9 and 12 months postoperatively were obtained. Identical exposure geometry was maintained. From the standardized radiographs digitized images were produced. Four experienced practitioners interpreted the radiographs and the digitized images. They assessed 59 pairs of images projected at random using a slide projector. On the left side, there was a reference image with no lesion, and on the right an image either with or without a lesion. Each reader was asked to rate each pair of images on a three-point scale: yes, absolutely sure that gain or loss was present; uncertain, if there was gain or loss; no, absolutely sure that no gain or loss was present. There was no time limit for each decision. Inter- and intra-examiner agreement was analyzed using the kappa-statistic for the diagnosis of periapical bone density changes in the periapical region at the different time points either in conventional pairs of radiographs or using digital subtraction images. RESULTS: The inter-examiner agreement (P < 0.001) and the intra-examiner agreement (P = 0.02) when digital pictures where evaluated were significantly higher than with conventional radiographs. CONCLUSIONS: A highly significantly better observer agreement was achieved by digital subtraction radiography during the evaluation of the outcome of root canal treatment on periapical lesions.

Adult↗

Can we talk? Importance of random-digit-dial surveys for injury prevention research.

Prevention research in public health requires quality data. In injury prevention research, "official" data sources, such as medical or law enforcement data, often do not possess the required depth or completeness. Self-reported data can fill this gap. Such data allow us to understand knowledge, attitudes, exposures, and behaviors associated with injury risk. Self-reported data are also needed to understand outcomes that are often missing from official sources, such as victimization by an intimate partner that is not reported because of concerns about legal consequences and less severe injuries from suicide attempts that go untreated. Data on risk and protective factors and specific types of violence exposures can often only be obtained by directly asking those affected. In addition, "official" data sources are rarely representative. Random-digit-dialing (RDD) surveys are a method of obtaining representative self-reported data. The RDD approach is relatively cost effective, handles non-English-speaking households with relative ease, and possesses a well-developed theory for constructing sample weights. However, there are significant challenges to using RDD surveys. These include declining participation rates; possible self-selection bias, since potential respondents can choose to opt out of the survey; and, with sensitive topics such as intimate partner violence, the need to anticipate potential risks for participants. This theme issue provides suggestions for how we can improve the design and implementation of RDD surveys in a manner that is both practical and ethical.

Behavioral Risk Factor Surveillance System↗

Digital doctors.

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Attitude of Health Personnel↗