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Pathological validation of auscultation of the elderly heart.

Systolic murmurs present in 129 geriatric patients followed to post-mortem were assessed as mitral or aortic in origin by simple clinical assessment alone. Post-mortem examination contradicted clinical findings in only 2% of cases. Mitral valve pathology, mostly post-inflammatory scarring or mucoid degeneration, was present in 50% of the cases with murmurs. There was a significant correlation between the presence of murmurs, particularly mitral murmurs, and congestive cardiac failure, and there was also a significant correlation with age. A tendency for aortic systolic murmurs to be associated with a higher mean systolic blood pressure was not significant and there was no significant association between systolic murmurs and ischaemic heart disease.

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Rapidly developing pseudohypertension after renal transplantation diagnosed by non-auscultated blood pressure measurement.

Pseudohypertension has been reported in elderly, diabetic and uraemic patients. A variety of diagnostic methods have been used, generally with poor results with the exception of arterial catheterisation. We report a case of pseudohypertension that developed in the year following a renal transplant and was diagnosed by the use of oscillometric and photoplethysmographic blood pressure measurement.

Auscultation↗

Auscultation of cervical and ocular bruits in extracranial carotid occlusive disease: a clinical and angiographic study.

The clinical and angiographic features of cervical and ocular bruits were correlated in 50 consecutive patients with severe extracranial internal carotid artery occlusive disease. Cervical bruits, generally localized to the carotid bifurcation, were highly associated (P = 0.004) with "tight" (residual lumen less than or equal to 2 mm) internal carotid artery stenosis, but significantly less often with a widely patent or occluded internal carotid artery. Angiographic features of a "slow-flow" state through a patent, but "tight" stenosis were identified as the apparent explanation for the absence of bruit in some patients. A unilateral ocular bruit contralateral to the side of internal carotid artery occlusion occurred in 9 of 10 patients, more often than an associated cervical bruit, and was interpreted as a sign of augmentation flow.

Arterial Occlusive Diseases↗

Clinical utility of chest auscultation in common pulmonary diseases.

In this investigation we applied the techniques of lung sound mapping and time-expanded wave-form analysis to four common diseases that involve the lung: interstitial pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF), and pneumonia (Pn). Twenty subjects were studied in each group. We also studied 15 subjects without evidence of lung disease. Differences in timing, character, and location were observed, which allowed separation among these groups. Multiple logistic regression models were created and tested by the bootstrap method. Regression models correctly classified 68 and 79% of subjects. Area under the receiver operating curve ranged from 0.96 for IPF and CHF to 0.80 for COPD. We conclude that auscultatory differences exist among common pulmonary conditions and that statistical models based on auscultatory data perform well in predicting diagnostic categories.

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