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At least 433 records · Page 24Linked to original sources
PubMed2004

Decreasing motion artifacts in calcium-dependent fluorescence transients from the perfused mouse heart using frequency filtering.

A strategy has been developed for the removal of motion artifact and noise in calcium-dependent fluorescence transients from the perfused mouse heart using frequency filtering. An analytical model indicates that the spectral removal of motion artifacts is independent of the phase shift of the motion waveform in the frequency domain, and thus to the time shift (or delay) of motion in the time domain. This is based on the "shift theorem" of Fourier analysis, which avoids erroneous correction of motion artifact when using the motion signal obtained using reflectance from the heart. Several major steps are adopted to implement this model for elimination of motion as well as detection noise from the fluorescence transient signals from the calcium-sensitive probe Rhod-2. These include (1) extracting the fluorescence calcium transient signal from the raw data by using power spectrum density (PSD) in the frequency domain by subtracting the motion recorded using the reflectance of excitation light, (2) digitally filtering out the random noise using multiple bandpass filters centralized at harmonic frequencies of the transients, and (3) extracting high frequency noise with a Gaussian Kernel filter method. The processed signal of transients acquired with excessive motion artifact is comparable to transients acquired with minimal motion obtained by immobilizing the heart against the detection window, demonstrating the usefulness of this technique.

Animals↗
PubMedDate not supplied

Reduction of respiratory motion artifacts in transverse relaxation rate (R2) images of the liver.

An empirical motion artifact suppression technique has been developed to reduce the respiratory motion artifacts in axial single spin-echo magnetic resonance (MR) images of the liver post-acquisition. The correction scheme is based on the observation that the dominant motion artifacts within abdominal MR images are ghosts that follow the profile and signal intensity of high signal intensity boundaries, such as those for the subcutaneous fat along the anterior abdominal wall. The technique is applied to the reduction of respiratory motion artifacts in a spin echo image series of the liver of an iron-loaded patient and of a manganese chloride phantom subject to respiratory motion. Subsequent improvements to transverse relaxation rate (R2) image analysis are then demonstrated on the motion-corrected spin echo images, illustrating the utility of the technique for application in the R2 image-based measurement and mapping of liver iron concentration.

Artifacts↗
PubMed2004

Factor analysis in both spatial and temporal domains of color blooming artifacts in ultrasound investigations utilizing contrast agents.

Color blooming artifacts can cause misinterpretations of normal and pathological structures during color Doppler flow imaging with ultrasound contrast agents (USCAs). These artifacts are characterized in both the spatial and temporal domains: in the spatial domain, artifacts result from wave propagation and the ultrasound system; and in the temporal domain, the color blooming time (CBT) is used to denote the duration of artifacts. In our experiments, CBT decreased from 86.7 to 46.8 s when the transmitting pressure was decreased from 370 to 180 kPa. From this, we conclude that an adaptive mechanical index can significantly shorten the CBT, which may in turn prolong the optimal viewing time during in vivo ultrasound investigations utilizing USCAs.

Artifacts↗
PubMed2005

Human movement analysis using stereophotogrammetry. Part 3. Soft tissue artifact assessment and compensation.

When using optoelectronic stereophotogrammetry, skin deformation and displacement causes marker movement with respect to the underlying bone. This movement represents an artifact, which affects the estimation of the skeletal system kinematics, and is regarded as the most critical source of error in human movement analysis. A comprehensive review of the state-of-the-art for assessment, minimization and compensation of the soft tissue artifact (STA) is provided. It has been shown that STA is greater than the instrumental error associated with stereophotogrammetry, has a frequency content similar to the actual bone movement, is task dependent and not reproducible among subjects and, of lower limb segments, is greatest at the thigh. It has been shown that in in vivo experiments only motion about the flexion/extension axis of the hip, knees and ankles can be determined reliably. Motion about other axes at those joints should be regarded with much more caution as this artifact produces spurious effects with magnitudes comparable to the amount of motion actually occurring in those joints. Techniques designed to minimize the contribution of and compensate for the effects of this artifact can be divided up into those which model the skin surface and those which include joint motion constraints. Despite the numerous solutions proposed, the objective of reliable estimation of 3D skeletal system kinematics using skin markers has not yet been satisfactorily achieved and greatly limits the contribution of human movement analysis to clinical practice and biomechanical research. For STA to be compensated for effectively, it is here suggested that either its subject-specific pattern is assessed by ad hoc exercises or it is characterized from a large series of measurements on different subject populations. Alternatively, inclusion of joint constraints into a more general STA minimization approach may provide an acceptable solution.

Adipose Tissue↗
PubMed2006

Reducing metal artifacts in cone-beam CT images by preprocessing projection data.

PURPOSE: Computed tomography (CT) streak artifacts caused by metallic implants remain a challenge for the automatic processing of image data. The impact of metal artifacts in the soft-tissue region is magnified in cone-beam CT (CBCT), because the soft-tissue contrast is usually lower in CBCT images. The goal of this study was to develop an effective offline processing technique to minimize the effect. METHODS AND MATERIALS: The geometry calibration cue of the CBCT system was used to track the position of the metal object in projection views. The three-dimensional (3D) representation of the object can be established from only two user-selected viewing angles. The position of the shadowed region in other views can be tracked by projecting the 3D coordinates of the object. Automatic image segmentation was used followed by a Laplacian diffusion method to replace the pixels inside the metal object with the boundary pixels. The modified projection data were then used to reconstruct a new CBCT image. The procedure was tested in phantoms, prostate cancer patients with implanted gold markers and metal prosthesis, and a head-and-neck patient with dental amalgam in the teeth. RESULTS: Both phantom and patient studies demonstrated that the procedure was able to minimize the metal artifacts. Soft-tissue visibility was improved near or away from the metal object. The processing time was 1-2 s per projection. CONCLUSION: We have implemented an effective metal artifact-suppressing algorithm to improve the quality of CBCT images.

Algorithms↗
PubMed2006

Stone artifacts and hominins in island Southeast Asia: new insights from Flores, eastern Indonesia.

This study reexamines the current understanding of Pleistocene stone-artifact assemblages in island Southeast Asia. A differentiation has long been made between assemblages of large-sized "core tools" and assemblages of small-sized "flake tools." "Core tool" assemblages are often argued to be the handiwork of early hominin species such as Homo erectus, while small-sized "flake tool" assemblages have been attributed to Homo sapiens. We argue that this traditional Southeast Asian perspective on stone tools assumes that the artifacts recovered from a site reflect a complete technological sequence. Our analyses of Pleistocene-age artifact assemblages from Flores, Indonesia, demonstrate that large pebble-based cores and small flake-based cores are aspects of one reduction sequence. We propose that the Flores pattern applies across island Southeast Asia: large-sized "core tool" assemblages are in fact a missing element of the small-sized flake-based reduction sequences found in many Pleistocene caves and rock-shelters. We conclude by discussing the implications of this for associating stone-artifact assemblages with hominin species in island Southeast Asia.

Animals↗
PubMed2005

Correction of concomitant gradient artifacts in experimental microtesla MRI.

Magnetic resonance imaging (MRI) suffers from artifacts caused by concomitant gradients when the product of the magnetic field gradient and the dimension of the sample becomes comparable to the static magnetic field. To investigate and correct for these artifacts at very low magnetic fields, we have acquired MR images of a 165-mm phantom in a 66-microT field using gradients up to 350 microT/m. We prepolarize the protons in a field of about 100 mT, apply a spin-echo pulse sequence, and detect the precessing spins using a superconducting gradiometer coupled to a superconducting quantum interference device (SQUID). Distortion and blurring are readily apparent at the edges of the images; by comparing the experimental images to computer simulations, we show that concomitant gradients cause these artifacts. We develop a non-perturbative, post-acquisition phase correction algorithm that eliminates the effects of concomitant gradients in both the simulated and the experimental images. This algorithm assumes that the switching time of the phase-encoding gradient is long compared to the spin precession period. In a second technique, we demonstrate that raising the precession field during phase encoding can also eliminate blurring caused by concomitant phase-encoding gradients; this technique enables one to correct concomitant gradient artifacts even when the detector has a restricted bandwidth that sets an upper limit on the precession frequency. In particular, the combination of phase correction and precession field cycling should allow one to add MRI capabilities to existing 300-channel SQUID systems used to detect neuronal currents in the brain because frequency encoding could be performed within the 1-2 kHz bandwidth of the readout system.

Algorithms↗
PubMed2006

Recursive artifact windowed-single tone extraction method (RAW-STEM) as periodic noise filter for electrophysiological signals with interfering transients.

The single tone extraction method (STEM) is a well developed algorithm for estimating the frequency, amplitude, and phase of one periodic signal or a single tone in complex temporal signals. This method is useful in neuroscience research since it provides an efficient simple means to remove line frequency noise present in many types of signal measurements. However, the method encounters problems when the signal contains transients such as a stimulus artifact which distort the estimation of power line parameters. Here we report a modification of STEM that overcomes this limitation. In this new method we call recursive artifact windowed (RAW)-STEM, the line frequency noise is removed for each single epoch by estimating the three parameters (frequency, amplitude and phase) of each line frequency after windowing the time period containing an interfering transient and iteratively applying the STEM. In a simulation study we evaluated its performance for electrophysiological data with a stimulus artifact and demonstrated advantages of the RAW-STEM over the classic STEM. The RAW-STEM is able to efficiently extract the 60 Hz parameter, requiring less than five iterations, with a precision of 0.007-2% depending on the parameters. It does not suffer from the problem of ringing following the stimulus artifact or distortion of electrophysiological signals. It is fast enough to be used for single trial analyses in electrophysiological studies. The RAW-STEM may be widely useful for the removal of periodic noise since it can be applied even when there are multiple interfering transients in the recording.

Algorithms↗
PubMed2006

The influence of computed tomography motion artifacts on computer-assisted surgery.

PURPOSE: Motion artifacts can significantly deteriorate the precision of a computer-assisted surgical intervention because they destroy the isometric representation of tomographic pictures. In the context of a study, the influence of typical motion artifacts on the precision of markerless laser registration in image-guided oral and maxillofacial surgery was analyzed, and quality factors for evaluation of the isometry of a computed tomography (CT) dataset were determined. PATIENTS AND METHODS: Twenty patients underwent markerless registration, the precision being determined by means of intraoral evaluation markers. Then the 20 CT datasets were used for simulation of a typical motion artifact. The precision of the overlay of the dataset was checked again on the navigation workstation, in absence of the patient. The navigation system used was the Surgical Segment Navigator SSN++ (University of Heidelberg, Heidelberg, Germany). RESULTS: The motion artifacts reduced the average patient registration from 1 to 4 mm. Quality factors for the isometry of a CT dataset were: the volume enclosed between the soft tissue mantles of the preoperative CT dataset and the intraoperative laser scan dataset, as well as the orientation of the normal vectors on the 3-dimensional reconstruction of the CT dataset. CONCLUSION: The isometry of a CT dataset should always be checked before performance of a computer assisted surgical intervention because anisometric datasets result in inaccurate patient registration and navigation.

Artifacts↗
PubMed2005

Susceptibility-matched envelope for the correction of EPI artifacts.

Fast gradient echo sequences, such as echo planer imaging (EPI) and spiral imaging, are vulnerable to artifacts resulting from B(0) inhomogeneities. A major contribution to these artifacts is the susceptibility variation across the head, which is most severe in regions adjacent to air-tissue interfaces, such as the mouth, nasal sinuses, ears and the cortex. Susceptibility artifacts can cause geometrical distortions in the image as well as loss of signal due to T(2)* dephasing. The extent of these artifacts increases with the main field, thus compromising the signal-to-noise ratio (SNR) benefit gained in higher fields. In the current work, inhomogeneity caused by susceptibility variations at the external boundary of the human body has been corrected by surrounding the organs with a liquid without hydrogen atoms and whose susceptibility is similar to that of the imaged organ. EPI experiments were conducted on head-sized phantom, human brain, hand and legs. This method causes minimal patient inconvenience and no interference with any function of the scanner, thus yielding a simple and efficient solution for the correction of B(0) variation.

Artifacts↗
PubMed2006

An independent component analysis-based approach on ballistocardiogram artifact removing.

Interest about simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) data acquisition has rapidly increased during the last years because of the possibility that the combined method offers to join temporal and spatial resolution, providing in this way a powerful tool to investigate spontaneous and evoked brain activities. However, several intrinsic features of MRI scanning become sources of artifacts on EEG data. Noise sources of a highly predictable nature such as those related to the pulse MRI sequence and those determined by magnetic gradient switching during scanning do not represent a major problem and can be easily removed. On the contrary, the ballistocardiogram (BCG) artifact, a large signal visible on all EEG traces and related to cardiac activity inside the magnetic field, is determined by sources that are not fully stereotyped and causing important limitations in the use of artifact-removing strategies. Recently, it has been proposed to use independent component analysis (ICA) to remove BCG artifact from EEG signals. ICA is a statistical algorithm that allows blind separation of statistically independent sources when the only available information is represented by their linear combination. An important drawback with most ICA algorithms is that they exhibit a stochastic behavior: each run yields slightly different results such that the reliability of the estimated sources is difficult to assess. In this preliminary report, we present a method based on running the FastICA algorithm many times with slightly different initial conditions. Clustering structure in the signal space of the obtained components provides us with a new way to assess the reliability of the estimated sources.

Adult↗
PubMed2006

Doppler artifacts and pitfalls.

With increasing technologic advances in ultrasound, its applications have continued to grow for the detection of pathology and physiology. To avoid misinterpretation of results, however, the Doppler US practitioner must understand the factors that produce a Doppler signal, whether vascular, motion, or artifact. Color or power Doppler artifacts can be verified by their atypical spectral waveform. Some artifacts, such as aliasing (for rapid detection of stenoses or arteriovenous fistulae) and the twinkle artifact (for identification of renal calculi and verification of other stones or crystals), are extremely useful diagnostically. Careful attention to the technical parameters of frequency, gain, filter and scale is required to correctly identify vascular patency or thrombosis, especially in slow-flowing vessels.

Artifacts↗
PubMed2005

Image artifact in dental cone-beam CT.

PURPOSE: The purpose of this study was to investigate the appearance and possible cause of an artifact seen in limited-volume cone-beam CT imaging. METHODS: A water-filled plastic cylinder was used as a phantom of the head. A test object was constructed as a bone-equivalent phantom to be imaged. The test object was variously positioned at the center of the phantom and near its margins. CT images of the test object were acquired using a 3DX Accuitomo system. RESULTS: In slice images with the test object positioned near the margin of the phantom, arch-shaped defects or deformities were observed on the side of the object. There was a negative correlation between the artifact and the CT value of the object. The artifact was larger in images scanned with a higher voltage. CONCLUSION: The probability that this artifact is caused by halation from the image intensifier (II) system is suggested.

Artifacts↗
PubMed1996

Instrument- and computer-related problems and artifacts in nuclear medicine.

Advances in gamma-camera design over the last 5 to 10 years have improved all aspects of image quality, particularly for tomographic imaging. As system complexity increases, it becomes more important that both the technologist and physician be able to recognize the various types of artifacts that can occur in gamma-camera systems and their potential impact on clinical studies. A thorough evaluation of the system at installation and a comprehensive quality control program will detect most problems that can occur. The most sensitive indicator of gamma-camera performance is uniformity. Because this measurement is performed on a daily basis, it is the principle tool in evaluating the status of the gamma-camera. Most artifacts related to the integrity of the detector head, computer system, and hard copy device can be detected on the uniformity image. For tomographic imaging, a quantitative determination of uniformity is needed to ensure that the system will not introduce ring artifacts into the patient data. Unlike planar imaging, the complex nature of tomographic imaging requires additional checks on system performance to ensure that other components of the system, such as the collimator, gantry, and imaging table, are not a source of artifact in the reconstructed image data. Failure of a system component can occur at any time and may be subtle and difficult to recognize in modern systems. In such an environment it becomes imperative that any unexpected finding in a clinical study be questioned with respect to a possible malfunction of some aspect of data acquisition and analysis.

Artifacts↗
PubMed2003

Camera artifacts producing the false impression of growth of choroidal melanocytic lesions.

PURPOSE: To report a camera artifact that masks portions of pigmented lesions while preserving overlying retinal details. DESIGN: Case report. METHODS: Cases collected from the authors' clinical practice were identified during review of fundus photos. An attempt was made to reproduce the artifact in a normal eye. RESULTS: Three cases were identified that demonstrated this artifact. CONCLUSION: Off-axis color photos can produce a reddish artifact that may blend imperceptibly with the surrounding retinal appearance and filter visualization of melanocytic pigment. This can mask a portion of a pigmented lesion and later may create a false impression of a larger lesion.

Aged↗
PubMed2002

Real-time multi-channel stimulus artifact suppression by local curve fitting.

We describe an algorithm for suppression of stimulation artifacts in extracellular micro-electrode array (MEA) recordings. A model of the artifact based on locally fitted cubic polynomials is subtracted from the recording, yielding a flat baseline amenable to spike detection by voltage thresholding. The algorithm, SALPA, reduces the period after stimulation during which action potentials cannot be detected by an order of magnitude, to less than 2 ms. Our implementation is fast enough to process 60-channel data sampled at 25 kHz in real-time on an inexpensive desktop PC. It performs well on a wide range of artifact shapes without re-tuning any parameters, because it accounts for amplifier saturation explicitly and uses a statistic to verify successful artifact suppression immediately after the amplifiers become operational. We demonstrate the algorithm's effectiveness on recordings from dense monolayer cultures of cortical neurons obtained from rat embryos. SALPA opens up a previously inaccessible window for studying transient neural oscillations and precisely timed dynamics in short-latency responses to electric stimulation.

Action Potentials↗
PubMed2001

In vitro simulation and quantification of temporal jitter artifacts in ECG-gated dynamic three-dimensional echocardiography.

The image quality of dynamic 3-D echocardiography is limited by temporal jitter artifacts that result from the asynchronous acquisition of video frames with the cardiac cycle. This paper analyzes the source and extent of these artifacts using in vitro studies. Dynamic 3-D images of a myocardial motion phantom were reconstructed and analyzed for eight cardiac motion patterns. The extent of temporal jitter artifacts was quantified, first, from the images by computing temporal jitter maps and, second, predicted from the motion waveforms. Temporal jitter appeared as a pattern of streak artifacts converging at the axis of rotation of the imaging plane, for the rotational scanning approach used in our study. The results of the experimental analysis techniques were compared with the waveform analysis using linear regression analysis. The least squares line showed good correlation between the data (r > 0.9) and its deviation from the line of identity was calculated to be <9%.

Artifacts↗
PubMed1998

Artifacts in intravascular ultrasound imaging during coronary artery stent implantation.

Intravascular ultrasound imaging is able to provide direct images of the stent meshwork. However, a paradoxical question remains unanswered: Why is it not possible to correct or prevent implantation defects by ultrasound-guided implantation? We postulate that these discrepancies are due to image artifacts. We performed an in vitro experiment allowing detection, physical characterization, and computerized simulations of the various aspects of these artifacts. The width of the echo of a strut is variable, dependent on its distance from the transducer. The stent strut echo orientation is variable, and depends on the position of the transducer inside the stent. The stent contour image depends on the position of the transducer. In conclusion, knowledge of these stent intravascular ultrasound image artifacts enabled us to discriminate accurately between artifacts and real stent implantation defects, and are indispensable for accurate qualitative and quantitative analyses of stents.

Arteries↗