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At least 433 records · Page 24Linked to original sources
PubMed1997

Plasticity of arterial vasculature during simulated weightlessness and its possible role in the genesis of postflight orthostatic intolerance.

Even after several decades of extensive research, the basic mechanism of postflight cardiovascular dysfunction has not yet been fully elucidated. It is now well recognized that multiple mechanisms might account for the frequent occurrence of significant postflight orthostatic intolerance. It has been found that all tissues adapt their design when exposed to sustained alteration in local activity and/or stress. The most obvious example is the musculo-skeletal system, structure and function of which might be severely affected during microgravity exposure. In an attempt to elucidate whether structure and function of cardiac and vascular smooth muscle might be affected by simulated by microgravity, a serial work was started several years ago. In this paper, we present our more recent findings on plasticity of arterial vasculature and its innervation state during and after simulated microgravity and its time course.

Adaptation, Physiological↗
PubMed1977

Effects of weightlessness, space orientation and light on geotropism and the formation of fruit bodies in higher fungi.

The effect of flight factors on the growth and development of the fruit bodies of the higher fungus Polyporus brumalis is investigated under the conditions of an experiment on the earth satellite Cosmos 690. Fungi were grown on the earth under conditions of simulated flight and transit; fungi were also grown in the laboratory at a temperature similar to that in flight, at various orientations and under various illuminations. Polyporus brumalis grows well on wort; it forms fruit bodies on long pedicles (up to 25 cm) and possesses a strongly marked negative geotropism. Investigations have shown that the formation of hymenium and pileus is induced by definite time exposures to light. In darkness the formation of fruit bodies takes place, but without formation of hymenium and pileus, and the rate of growth is greater than in light. The strong negative geotropism remains in fruit bodies when developed in darkness and with test-tubes in a vertical position. When the test-tube orientation is changed the pedicles change direction in darkness as well as in light. In maintaining their negative geotropism the fruit bodies bend with changes of space orientation. In the absence of gravity a disorientation of fruit bodies takes place, and the pedicles are strongly twisted into a spiral or into a ball. A flattened type of fruit body can also occur. Such a picture of growth and formation was not observed in control samples. Thus, there is a strong dependence of the formation of the fruit body of Polyporus brumalis on space orientation, gravity and light.

Gravitropism↗