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At least 433 records · Page 24Linked to original sources
PubMed2001

The effect of wearing a back belt on spine kinematics during asymmetric lifting of large and small boxes.

STUDY DESIGN: A crossover design was used to evaluate kinematic measurements collected with an infrared-based motion measurement system. OBJECTIVES: To evaluate belt effects on spine kinematics during asymmetric lifting of large and small boxes and to test for carryover effects between trials from belts. SUMMARY OF BACKGROUND DATA: Conflicting evidence in the literature exists regarding whether belts are beneficial or detrimental to manual material handlers. Studies have not examined belt effects when lifting different sized boxes, nor carryover effects from belts. METHODS: Twenty-eight subjects with manual-handling experience (17 male and 11 female) were randomly assigned to lift either a large or small box (weighing 9.4 kg), from a sagittally symmetric origin at pallet height to a 79 cm height, 60 degrees to the right. Spine flexion, lateral bending and twisting, hip and knee flexion, and angular velocity measurements of the torso with respect to the pelvis were collected for each of three lifting periods, 50 lifts each at 3 lifts per minute, with 18-minute breaks between periods. RESULTS: Belts significantly reduced maximum spine flexion, spine flexion and extension angular velocities, and torso left lateral bending angular velocity, and increased hip and knee flexion, regardless of box size. When lifting large boxes, belts significantly reduced torso right lateral bending and torso left twisting. No significant differential carryover effects were detected from belts. CONCLUSIONS: Subjects with belts lifted more slowly and used more of a squat-lift technique, regardless of box size. Belts reduced more torso motions while lifting large boxes.

Adolescent↗
PubMed1997

The effects of inhomogeneities and anisotropies on electrocardiographic fields: a 3-D finite-element study.

The aim of this study was to quantify the effects of selected inhomogeneities and anisotropies on computed electric potential fields associated with the electrocardiographic forward problem. The model construction was based on the Utah Torso model and included geometry for major anatomical structures such as subcutaneous fat, skeletal muscle, and lungs, as well as for epicardial fatpads, major arteries and veins, and the sternum, ribs, spine, and clavicles. Measured epicardial potentials served as the electrical source for solutions to the electrocardiographic forward problems computed using the finite element method (FEM). The geometry of the torso model for each simulation was constant, but different combinations of conductivities were assigned to individual organs or tissues. Comparisons of different conductivity combinations followed one of two basic schemes: 1) a homogeneous torso served as the reference against which we compared simulations with a single organ or tissue and assigned its nominal conductivity, or 2) a fully inhomogeneous torso served as the reference and we removed the effect of individual organs or tissues by assigning it the homogeneous conductivity value. When single inhomogeneities were added to an otherwise homogeneous isotropic model, anisotropic skeletal muscle (at a 15:1 anisotropy ratio) and the right and left lung had larger average effects (12.8, 12.7, and 12.1% relative error (RE), respectively) than the other inhomogeneities tested. Our results for removing single inhomogeneities show that the subcutaneous fat, the anisotropic skeletal muscle (with the degree of anisotropy equal to 7:1), and the lungs have larger average impacts on the body surface potential distributions than other elements of the model (with values of 14.9, 12.6, and 11.7% RE, respectively). The results also show that the size of the effect depended strongly on the distribution of epicardial potentials. The results of this study suggest that accurate representation of tissue inhomogeneity has a significant effect on the accuracy of the forward solution, with regions near the torso surface playing a larger role, in general, than those near the heart.

Anisotropy↗
PubMed1995

Beam hardening errors in post-processing dual energy quantitative computed tomography.

A computer simulation study was performed to assess the errors due to x-ray beam hardening in the fat and bone estimates of a post-processing dual-energy quantitative computed tomography technique. The "central" calibration method was employed in which calibration standards are inserted within a torso phantom of a size similar to that of the "patient." Although beam hardening errors are reduced with this method, they still occur as a result of mismatches between the torso phantom and patient body sizes. Two mismatch situations were investigated. In one, a single torso phantom was used for all subject sizes (i.e., one-size-fits-all). In the other, closest matches were made from a set of three different sized torso phantoms (small, medium, and large). In all cases, the compositions of the calibration standards that were inserted into the torso phantoms consisted of bone, fat (glycerol trioleate), and an average fat-free red marrow. Fifteen patient sizes were simulated ranging from 20 to 34 cm in diameter. There were 21 patients of each size. The vertebrae in these subjects contained known amounts of bone mixed in marrows of composition determined from chemical analyses of cadaver marrow samples. Vertebrae consisting of mixtures of the calibration standard materials were also studied. The computed effective x-ray beam energies at the vertebra location for the various subject sizes ranged from 54.3 to 56.4 keV at 80 kVp and from 74.4 to 78.8 keV at 140 kVp.(ABSTRACT TRUNCATED AT 250 WORDS)

Adipose Tissue↗
PubMed2005

Modified electrode placement must be recorded when performing 12-lead electrocardiograms.

BACKGROUND: Local observation has suggested that placing limb leads on the torso when recording the standard 12-lead resting electrocardiogram (ECG) has become commonplace. This non-standard modification has the important advantages of ease and speed of application, and in an emergency may be applied with minimal undressing. Limb movement artefact is also reduced. It is believed that ECGs obtained with torso electrodes are interchangeable with standard ECGs and any minor electrocardiographic variations do not affect diagnostic interpretation. STUDY DESIGN: The study compared 12-lead ECGs in 100 patients during routine electrocardiography, one being taken in the approved way and one taken with modified limb electrodes. RESULTS: It was found that the use of torso leads produced important amplitude and waveform changes associated with a more vertical and rightward shift of the QRS frontal axis, particularly in those with abnormal standard ECGs. Such changes generated important ECG abnormalities in 36% of patients with normal standard ECGs, suggesting "heart disease of electrocardiographic origin". In those with abnormal standard ECGs, moving the limb leads to the torso made eight possible myocardial infarcts appear and five inferior infarcts disappeared. Twelve others developed clinically important T wave or QRS frontal axis changes. CONCLUSIONS: It is vital that ECGs should be acquired in the standard way unless there are particular reasons for not doing so, and that any modification of electrode placement must be reported on the ECG itself. Marking the ECG "torso-positioned limb leads" or "non-standard" should alert the clinician to its limitations for clinical or investigative purposes, as any lead adaptation may modify the tracing and could result in misinterpretation.

Adult↗
PubMed1984

Heat exchange during upper- and lower-body exercise.

This study examined evaporative and dry heat exchange during upper- and lower-body exercise. Four male subjects performed arm-crank or cycle exercise at the same O2 uptake level (approximately 1.6 l/min) in an environment facilitating dry heat exchange [radiative and convective (R + C)] [ambient temperature (Ta) = 18 degrees C, dew-point temperature (Tdp) = 14 degrees C] and an environment facilitating evaporative heat loss (Esk) (Ta = 35 degrees C, Tdp = 14 degrees C). (R + C) was determined from the torso with a net radiometer and from the limbs with heat flow discs, whereas Esk was determined from the torso and limbs by ventilated dew-point sensors. In both environments neither esophageal temperature nor mean skin temperature were different between exercise types (P greater than 0.05). Torso (R + C) was significantly (P less than 0.05) greater during arm-crank than during cycle exercise in both environments. Torso Esk, as well as arm (R + C), and arm Esk were not different (P greater than 0.05) between exercise types in each environment. Leg (R + C) was greater (P less than 0.05) during cycle than during arm-crank exercise in the 18 degrees C environment, whereas leg Esk was greater (P less than 0.05) during cycle than during arm-crank exercise in the 35 degrees C environment. These data indicate that to compensate for greater torso sensible heat loss during upper body exercise lower body exercise elicits additional (R + C) or Esk from the legs. The avenue for this compensatory sensible and insensible heat loss depends upon the differential heat transfer coefficients which influence tissue conductivity and mass transfer.

Adult↗
PubMed2006

A convenient scheme for coupling a finite element curvilinear mesh to a finite element voxel mesh: application to the heart.

BACKGROUND: In some cases, it may be necessary to combine distinct finite element meshes into a single system. The present work describes a scheme for coupling a finite element mesh, which may have curvilinear elements, to a voxel based finite element mesh. METHODS: The method is described with reference to a sample problem that involves combining a heart, which is defined by a curvilinear mesh, with a voxel based torso mesh. The method involves the creation of a temporary (scaffolding) mesh that couples the outer surface of the heart mesh to a voxel based torso mesh. The inner surface of the scaffolding mesh is the outer heart surface, and the outer surface of the scaffolding mesh is defined by the nodes in the torso mesh that are nearest (but outside of) the heart. The finite element stiffness matrix for the scaffolding mesh is then computed. This stiffness matrix includes extraneous nodes that are then removed, leaving a coupling matrix that couples the original outer heart surface nodes to adjacent nodes in the torso voxel mesh. Finally, a complete system matrix is assembled from the pre-existing heart stiffness matrix, the heart/torso coupling matrix, and the torso stiffness matrix. RESULTS: Realistic body surface electrocardiograms were generated. In a test involving a dipole embedded in a spherical shell, relative error of the scheme rapidly converged to slightly over 4%, although convergence thereafter was relatively slow. CONCLUSION: The described method produces reasonably accurate results and may be best suited for problems where computational speed and convenience have a higher priority than very high levels of accuracy.

Algorithms↗
PubMed2003

Isoflurane action in spinal cord indirectly depresses cortical activity associated with electrical stimulation of the reticular formation.

UNLABELLED: Anesthetics act in the spinal cord to ablate both movement and the ascending transmission of nociceptive information. We investigated whether a spinal cord action of isoflurane affected cortical activity as determined by the electroencephalogram desynchronization that occurs after electrical stimulation of the midbrain reticular formation (MRF). Six goats were anesthetized with isoflurane, and neck dissections were performed to permit differential isoflurane delivery to the head and torso. The electroencephalogram was recorded before, during, and after focal electrical stimulation (0.05, 0.1, 0.2, 0.3, and 0.4 mA) in the MRF; in each animal, the brain isoflurane was maintained constant ( approximately 1%). When the torso isoflurane was 0.3% +/- 0.1%, the spectral edge frequency after MRF electrical stimulation (15.3 +/- 1.7 Hz, averaged across all stimulus currents) was more than the spectral edge frequency when the torso isoflurane was 1.2% +/- 0.2% (12.9 +/- 1.0 Hz, averaged across all stimulus currents; P < 0.05). Bispectral index values were similarly affected: 60 +/- 6 when torso isoflurane was low versus 53 +/- 7 at high torso isoflurane (P < 0.05). These results suggest that a spinal depressant action of isoflurane on ascending somatosensory transmission can modulate reticulo-thalamocortical arousal mechanisms, hence possibly reducing anesthetic requirements for unconsciousness and amnesia. IMPLICATIONS: Isoflurane action in the spinal cord indirectly reduces the cortical activity associated with electrical stimulation of the reticular formation, an effect that might contribute to anesthetic-induced amnesia and unconsciousness.

Anesthetics, Inhalation↗
PubMed2005

Carbon dioxide depresses the F wave by a central, not peripheral, mechanism during isoflurane anesthesia.

Carbon dioxide (CO(2)) has anesthetic properties and has been reported to depress the F wave of the evoked electromyogram; the F wave is thought to reflect motoneuron excitability. Anesthetics such as isoflurane also depress the F wave. Because CO(2) can depress muscle contractile function, as well as spinal cord neurons, it is unclear whether CO(2) depresses the F wave via a central or peripheral mechanism. We anesthetized rabbits with isoflurane (1.4%) and prepared for hindlimb bypass (with a membrane oxygenator) whereby the partial pressures of CO(2) in the hindlimb muscle and torso could be independently adjusted. The F wave was recorded from the hindlimb plantar muscles when the CO(2) was normal to the hindlimb and torso, and when it was increased (to approximately 90 mm Hg) in the hindlimb, the torso, or both. Increasing the CO(2) to just the hindlimb had no significant effect on the F-wave amplitude, but increasing the CO(2) to the torso depressed the F wave to 52% +/- 32% of control; adding CO(2) to the hindlimb during torso hypercarbia did not result in any additional depression of the F wave. CO(2) depressed the F wave via a central, not peripheral, mechanism, although the precise mechanism is unknown.

Anesthesia, Inhalation↗
PubMed2006

An electromyographic analysis of commercial and common abdominal exercises: implications for rehabilitation and training.

STUDY DESIGN: A repeated-measures, counterbalanced design. OBJECTIVES: To test the effectiveness of 7 commercial abdominal machines (Ab Slide, Ab Twister, Ab Rocker, Ab Roller, Ab Doer, Torso Track, SAM) and 2 common abdominal exercises (crunch, bent-knee sit-up) on activating abdominal and extraneous (nonabdominal) musculature. BACKGROUND: Numerous abdominal machine exercises are believed to be effective in activating abdominal musculature and minimizing low back stress, but there are minimal data to substantiate these claims. Many of these exercises also activate nonabdominal musculature, which may or may not be beneficial. METHODS AND MEASURES: A convenience sample of 14 subjects performed 5 repetitions for each exercise. Electromyographic (EMG) data were recorded for upper and lower rectus abdominis, external and internal oblique, pectoralis major, triceps brachii, latissimus dorsi, lumbar paraspinals, and rectus femoris, and then normalized by maximum muscle contractions. RESULTS: Upper and lower rectus abdominis EMG activities were greatest for the Ab Slide, Torso Track, crunch, and Ab Roller, while external and internal oblique EMG activities were greatest for the Ab Slide, Torso Track, crunch, and bent-knee sit-up. Pectoralis major, triceps brachii, and latissimus dorsi EMG activities were greatest for the Ab Slide and Torso Track. Lumbar paraspinal EMG activities were greatest for the Ab Doer, while rectus femoris EMG activities were greatest for the bent-knee sit-up, SAM, Ab Twister, Ab Rocker, and Ab Doer. CONCLUSIONS: The Ab Slide and Torso Track were the most effective exercises in activating abdominal and upper extremity muscles while minimizing low back and rectus femoris (hip flexion) activity. The Ab Doer, Ab Twister, Ab Rocker, SAM, and bent-knee sit-up may be problematic for individuals with low back pathologies due to relatively high rectus femoris activity.

Abdominal Muscles↗
PubMed2000

Isoflurane depresses electroencephalographic and medial thalamic responses to noxious stimulation via an indirect spinal action.

UNLABELLED: Anesthetics such as isoflurane act in the spinal cord to suppress movement in response to noxious stimulation. Spinal anesthesia decreases hypnotic/sedative requirements, possibly by decreasing afferent transmission of stimuli. We hypothesized that isoflurane action in the spinal cord would similarly depress the ascending transmission of noxious input to the thalamus and cerebral cortex. In six isoflurane-anesthetized goats, we measured electroencephalographic (EEG) and thalamic single-unit responses to a clamp applied to the forelimb. Cranial bypass permitted differential isoflurane delivery to the torso and cranial circulations. When the cranial-torso isoflurane combination was 1.3% +/- 0.2%-1.0% +/- 0.4% the noxious stimulus did not evoke significant changes in the EEG or thalamic activity: 389 (153-544) to 581 (172-726) impulses/min, (median, 25th-75th percentile range, P: > 0.05). When the cranial-torso isoflurane combination was 1.3% +/- 0.2%-0.3% +/- 0.2%, noxious stimulation increased thalamic activity: 804 (366-1162) to 1124 (766-1865) impulses/min (P: < 0.05), and the EEG "desynchronized": total EEG power decreased from 25 +/- 20 microV(2) to 12 +/- 8 microV(2) (P: < 0.05). When the cranial-torso isoflurane was 1.7% +/- 0.1%-0.3% +/- 0.2%, the noxious stimulus did not significantly affect thalamic: 576 (187-738) to 1031 (340-1442) impulses/min (P: > 0.05), or EEG activity. The indirect torso effect of isoflurane on evoked EEG total power (12.6 +/- 2.7 microV(2)/vol%, mean +/- SE) was quantitatively similar to the direct cranial effect (17.7 +/- 3.0 microV(2)/vol%; P: > 0.05). These data suggest that isoflurane acts in the spinal cord to blunt the transmission of noxious inputs to the thalamus and cerebral cortex, and thus might indirectly contribute to anesthetic endpoints such as amnesia and unconsciousness. IMPLICATIONS: Isoflurane action in the spinal cord diminished the transmission of noxious input to the brain. Because memory and consciousness are likely dependent on the "arousal" state of the brain, this indirect action of isoflurane could contribute to anesthetic-induced amnesia and unconsciousness.

Anesthetics, Inhalation↗
PubMed1986

Q-wave infarction: pathophysiology of body surface potential map and ventriculographic patterns in anterior and inferior groups.

To define and relate the body surface electrocardiographic and left ventricular wall motion patterns in the acute phase of Q-wave infarction, we recorded 120-lead body surface potential maps and radionuclear angiograms in 29 patients on the fifth day of their first infarction. By standard 12-lead electrocardiographic criteria, 17 patients were designated as anterior infarction and 12 as inferior infarction. Body surface map infarct patterns in the anterior group were characterized primarily by abnormal Q-wave, negative Q-zone and positive ST-segment integral patterns over the anterior torso and little reciprocal change. The maps of the inferior patient group were characterized primarily by depolarization and repolarization infarct patterns over the inferior torso and marked reciprocal changes in all integral patterns over the anterior torso. Both groups displayed infarct patterns over a common area of the right anterior-inferior torso. In the anterior group depolarization minima and repolarization maxima were clustered in a small precordial area; in the inferior group the same extrema were widely scattered over the inferior torso, both anteriorly and posteriorly. Segmental left ventricular wall motion analysis revealed that the 3 most commonly and most severely involved segments were the same in both infarct groups--apical, infero-apical and antero-lateral. Basal septum and antero-basal segmental dysfunction were exclusive to the anterior group; postero-lateral and infero-basal involvement, to the inferior group.(ABSTRACT TRUNCATED AT 250 WORDS)

Action Potentials↗
PubMed1998

A modified crash brace position for aircraft passengers.

BACKGROUND: In 1989, a Boeing 737-400 aircraft crashed at Kegworth, near Nottingham, England. The survivors suffered a large number of pelvic and lower limb injuries, and approximately one-third of the passengers died. Subsequent research has suggested that the "brace-for-impact" position that passengers are advised to adopt prior to a crash landing might be modified in order to reduce the incidence of such injuries. The aim of this research was to evaluate biomechanically such a modified crash brace position. HYPOTHESIS: A modified brace position would help to prevent injuries to some passengers in the event of an impact aircraft accident. METHODS: Impact testing on forward-facing seats was performed at the Royal Air Force Institute of Aviation Medicine, Farnborough, England. Aircraft seats, mounted on a sled, were propelled down a track to impact at -16 Gx. A test dummy was used as the experimental model. Four dummy positions were investigated: a) upper torso braced forward and lower legs inclined slightly rearward of the vertical; b) upper torso braced forward and lower legs inclined forward; c) upper torso upright and lower legs inclined slightly rearward of the vertical; and d) upper torso upright and lower legs inclined forward. The impact pulses used were based on Federal Aviation Administration guidelines. Transducers located in the head, spine, and lower limbs of the dummy recorded the forces to which each body segment was exposed during the impact. These forces were compared for each brace position. RESULTS: Impact testing revealed that the risk of a head injury as defined by the head injury criterion was greater in the upright position than in the braced forward position. The risk of injury to the lower limbs was dependent in part on the flailing behavior of the limbs. Flailing did not occur when the dummy was placed in a braced, legs-back position. CONCLUSIONS: A modified brace position would involve passengers sitting with the upper torso inclined forward so that the passenger's head rested against the structure in front, if possible. The legs would be positioned with the feet resting on the floor in a position slightly behind the knee. The position differs from those previously recommended in that the feet are positioned behind the knee. This study suggests that such a position would reduce the potential for head and lower limb injury in some passengers, given that only a single seat type and single size of occupant have been evaluated. Standardization to such a position would improve passenger understanding and compliance. Such a recommendation should not obscure the fact that an occupant seated in a forward-facing aircraft seat, restrained only by a lap belt, is exposed to considerable forces during an impact accident. Such forces are capable of producing injuries in the femur, pelvis, and lumbar spine.

Accidents, Aviation↗
PubMed1996

The effect of water leakage on the results obtained from human and thermal manikin tests of immersion protective clothing.

The effect of both the volume and location of water leakage on the protection provided by an uninsulated immersion suit was investigated using human subjects and, in corresponding experiments, an immersion thermal manikin. Three volumes of "leakage" to the torso (200, 500 and 1000 ml) were examined, as were two conditions in which no leakage was simulated and one condition in which a 500-ml leak to the limbs was simulated. All leakages were introduced in a standardised way before immersion. The measurements of clothing insulation obtained, both from the manikin and the humans, were in general agreement. The human experimentation provided some support for a 200-ml limit to water leakage in tests of immersion suits. Rectal and aural temperatures remained significantly (P < 0.05) higher when a 500-ml leak was applied to the limbs rather than the torso; this was primarily due to greater heat flow through and from the torso (back) during the immersions with torso wetting. The physiological responses and anthropometric characteristics which determine this response are not present in manikins; the implications of this for the application and design of immersion thermal manikins, as well as the protection of those at risk of immersion in cold water, are discussed. It is concluded that using immersion thermal manikins to provide a single overall measure of clothing insulation will not necessarily distinguish between suits which provide quite different levels of protection for humans.

Body Temperature↗
PubMed1985

Fitness changes of Naval women following aerobic based programs featuring calisthenic or circuit weight training exercises.

Two research investigations were undertaken to determine the effects of experimental aerobic/circuit weight training (A/CWT) and standard Navy aerobic/calisthenic (A/CAL) training on fitness parameters. Study I Subjects were 22 female officer and enlisted personnel aged 24 to 34 years (mean = 28.2). The women followed a 10-week A/CWT program working at an intensity of 60% of determined one repetition maximum (1RM). These women showed significant (p less than 0.05) improvements in dynamic muscular strength, muscular endurance, and stamina. Only upper torso static strength was unaffected by training. Study II Participants were 115 female recruits aged 17 to 34 years (mean = 20.4). They were randomly assigned to one of three training groups: 1) aerobic/calisthenic training (A/CAL) (N = 58); 2) aerobic/circuit weight training at 40% (A/CWT-40) of maximum strength determined for a single repetition (1RM) of the lifting exercises (N = 26); and 3) aerobic/circuit weight training at 70% (A/CWT-70) of determined 1RM (N = 30). Results showed that standard recruit A/CAL training did not significantly (p less than 0.05) enhance upper torso dynamic strength (except the lat-pulldown test) or stamina. A/CWT-70 elicited significantly (p less than 0.05) higher gains in several tests of upper torso strength than A/CAL or A/CWT-40. These results suggest that A/CWT offers a way to develop the required upper torso strength of Navy women.

Adult↗
PubMed2000

Propofol directly depresses lumbar dorsal horn neuronal responses to noxious stimulation in goats.

PURPOSE: We tested the hypothesis that propofol, acting in the brain, would either enhance, or have no effect, on lumbar dorsal horn neuronal responses to a noxious mechanical stimulus applied to the hindlimb. We recorded the response of lumbar dorsal horn neurons during differential delivery of propofol to the brain and torso of goats. METHODS: Goats were anesthetized with isoflurane and neck dissections performed which permitted cranial bypass. A laminectomy was made to allow microelectrode recording of lumbar dorsal horn neuronal activity. Isoflurane was maintained at 0.8+/-0.1% to both head and torso throughout the study. During cranial bypass propofol was separately administered to the torso (1 mg x kg(-1), n = 7; 3.75 mg x kg(-1), n = 8) or cranial (0.04 mg x kg(-1), n = 7; 0.14 mg kg(-1), n = 8) circulations. RESULTS: Propofol administered to the torso depressed dorsal horn neuronal responses to noxious stimulation: low dose: 500+/-243 to 174+/-240 impulses x min(-1) at one minute post-injection, P<0.001; high dose: 478+/-204 to 91+/-138 impulses x min(-1) at one minute post-injection, P<0.05). Propofol administered to the cranial circulation had no effect: low dose: 315+/-150 to 410+/-272 impulses x min(-1), P>0.05; high dose: 462+/-261 to 371+/-196 impulses x min(-1), P>0.05. CONCLUSIONS: These data indicate that propofol has a direct depressant effect on dorsal horn neuronal responses to noxious stimulation, with little or no indirect supraspinal effect.

Analysis of Variance↗
PubMed1982

Evaluation of normal variations in S-T segment patterns by body surface isopotential mapping: S-T segment elevation in absence of heart disease.

S-T segment elevation is commonly observed in the electrocardiogram of normal persons. To study the possible origins of such patterns, 45 normal volunteers were examined. Electrocardiographic potentials were registered from 150 torso electrodes and processed to construct isopotential maps at 2 ms intervals throughout the QRS-T interval. The maximal potentials recorded from any of the 150 electrodes were 198 +/- 76.4 and 272.1 +/- 84.2 microV at instants 40 and 80 ms into the S-T segment, respectively. Maximal voltages recorded by the six standard precordial V leads at these respective time points were 109.7 +/- 57.0 and 163.6 +/- 66.9 microV. Torso maximal potentials were significantly stronger than were those sensed by V leads; the two were significantly correlated but predictability was limited. The duration of overlap between the onset of ventricular recovery and the end of the excitation was determined from isopotential maps and ranged rom 4 to 16 ms. There was no significant correlation (p greater than 0.05) between these values and either torso or V lead potentials at either 40 or 80 ms into S-T segment. These data suggest that (1) standard precordial leads do not accurately predict maximal torso potentials during the S-T segment, and (2) the degree of overlap between repolarization and depolarization is not a major determinant of precordial voltage. Hence, the rationale for use of the term "early repolarization" to describe this clinical condition is not substantiated.

Adolescent↗
PubMed1988

The adjuvant role of two cycles of MOPP and low-dose lung irradiation in stage IA through IIB Hodgkin's disease: preliminary results.

Fifty-eight laparotomy-staged I and II patients with upper torso presentations of Hodgkin's disease and 8 patients with lymphangiogram-staged lower torso disease were treated with radiotherapy alone or with 2 cycles of MOPP and radiotherapy. Patients with upper torso disease with either no mediastinal or only small mediastinal disease without hilar involvement and with no "B" symptoms were treated with mantle radiotherapy alone. Patients with large mediastinal masses or hilar disease were treated with 2 cycles of MOPP followed by definitive mantle irradiation and low dose lung irradiation. Those for whom "B" symptoms were the only adverse prognostic feature received 2 cycles of MOPP and mantle radiotherapy. Patients with lower torso disease were treated with radiotherapy alone if the disease was limited to the pelvis. Those with more extensive disease received 2 cycles of MOPP prior to radiotherapy. The 4-year survival for all 66 patients was 97%. The corresponding disease-free and freedom from second relapse figures were 77% and 92%. Survival for the patients with unfavorable presentations who received 2 cycles of MOPP and radiotherapy was 100%. It was 92% for the group with favorable presentations who were treated with radiotherapy only.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed2006

Lateral impact injuries with side airbag deployments--a descriptive study.

The present study was designed to provide descriptive data on side impact injuries in vehicles equipped with side airbags using the United States National Automotive Sampling System (NASS). The database was queried with the constraint that all vehicles must adhere to the Federal Motor Vehicle Safety Standards FMVSS 214, injured occupants be in the front outboard seats with no rollovers or ejections, and side impacts airbags be deployed in lateral crashes. Out of the 7812 crashes in the 1997-2004 weighted NASS files, AIS > or = 2 level injuries occurred to 5071 occupants. There were 3828 cases of torso-only airbags, 955 cases of torso-head bag combination, and 288 inflatable tubular structure/curtain systems. Side airbags were not attributed to be the cause of head or chest injury to any occupant at this level of severity. The predominance of torso-only airbags followed by torso-head airbag combination reflected vehicle model years and changing technology. Head and chest injuries were coupled for the vast majority of occupants with injuries to more than one body region. Comparing literature data for side impacts without side airbag deployments, the presence of a side airbag decreased AIS=2 head, chest, and extremity injuries when examining raw data incidence rates. Although this is the first study to adopt strict inclusion-exclusion criteria for side crashes with side airbag deployments, future studies are needed to assess side airbag efficacy using datasets such as matched-pair occupants in side impacts.

Abdominal Injuries↗