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At least 433 records · Page 24Linked to original sources
PubMed1982

Chondrogenesis in repair of articular cartilage defects by free periosteal grafts in rabbits.

The origin of the cartilaginous tissue in articular defects after periosteal grafting was studied histologically in 6-month-old rabbits. The grafts were taken from the tibia and transplanted to artificial defects in the femoral articular cartilage. An isolating Nuclepore filter, hindering the penetration of cells, was placed between the graft and the cancellous bone, in order to trace the origin of the proliferating cells. The histological results revealed that the cartilage tissue which proliferated in the defect originated from the periosteal graft and not from the subchondral bone. The effect of the depth of the defect was studied by making a superficial and deep part in the defect. Cartilage tissue was found in both parts of the defect, though there was less in the more superficial defect.

Animals↗
PubMed1983

Osteochondrogenesis of free periosteal grafts in the rabbit iliac crest.

The influence of the bone marrow, cortical bone and apophyseal cartilage of the iliac crest on osteochondrogenesis from free autogenous periosteal grafts was studied histologically in 8-week-old rabbits. Tibial periosteum was transplanted around the iliac crest, from which the periosteum had been removed from the inner side, periosteum and cortical bone in an area on the outer side and perichondrium from the apophyseal cartilage. Most bone formation occurred in the area with periosteum in contact with the bone marrow of the cancellous bone. By means of an isolating Nucleopore filter, it was revealed that the most vigorous of this bone formation originated from the periosteal graft. Further, it was noted that in the series with the Nucleopore filter, bone formation was slower than in the series without the filter, suggesting some inductive factors. No bone formation occurred in the apophyseal area.

Animals↗
PubMed1985

Glued periosteal grafts in the knee.

Periosteal grafting was performed in 4 patients with osteochondritis dissecans of the medial femoral condyle and 1 patient with osteonecrosis of the lateral femoral condyle following prednisone therapy. The lesions were drilled out deep into the cancellous bone. The periosteal graft was taken from the medial facet of the tibia and fixed to the excavated bony defect by the tissue glue Fibrinkleber Human Immuno (Tisseel). The patients were followed clinically, by arthroscopic examination and by radiography at 3, 6, and 12 months. After 1 year the borderline between the new and surrounding cartilage was hardly visible.

Adolescent↗
PubMed1990

Indomethacin influences Moloney's sarcoma and associated periosteal osteogenesis in the mouse.

The effect of indomethacin on periosteal osteogenesis mediated by the Moloney sarcoma virus was studied using a mouse model. In the indomethacin-treated animals, the development of sarcoma was inhibited, as evaluated by the tumor incidence, tumor size, and maximal tumor duration. Periosteal osteogenesis mediated by this sarcoma was lower than in saline-treated control mice.

Animals↗
PubMed1995

Periosteal response to transient ischemia. Histological studies on the rat tibia.

Complete arrest of blood flow was induced for 4.5 hours in the left hindlimb of Wistar rats by a tourniquet applied proximally to the thigh. Histologically the periost of the tibial bone after 3 days showed marked hypertrophy and hyperplasia of the periosteal cells with an osteogen differentiation. This response is similar to the initial formation of external callus during fracture healing. Transient ischemia may be an important factor in initiating fracture healing.

Animals↗
PubMed1996

Periosteal insulin-like growth factor I and bone formation. Changes during tibial lengthening in rabbits.

We investigated changes in periosteal insulin-like growth factor I (IGF-I) during tibial lengthening. In 37 rabbits, an osteotomy of the right middle tibia was made and fixed by a unilateral external fixator. The rabbits were randomized into 6 groups: the tibiae were distracted at 0.5 mm/day up to 4 weeks and the animals killed after 2 weeks, 4 weeks or 6 weeks, for each period there was a control group with no distraction. Periosteal IGF-I was measured by radioimmunoassay and bone formation was quantified by CT scanning. During bone lengthening, CT showed moderate bone formation, while IGF-I was increased. When lengthening was stopped, IGF-I returned to a basal level, and CT scanning showed considerable bone formation. Our study suggests that IGF-I plays a role in an early stage of bone formation.

Animals↗
PubMed1997

Severe hindlimb ischemia causes periosteal proliferation in the rat tibia.

In this rat study, we found tibial periosteal hyperplasia and hypertrophy, and appositional new bone formation 3 days after transient hindlimb ischemia. This response was positively correlated to the extent of muscle necrosis, which was increased either by raising the environmental temperature during ischemia or by prolonging the period of ischemia. By changing the temperature from 21 degrees C to 34 degrees C, the area periost in percent of the total tibial area was increased from 5 to 17, and by changing the duration of ischemia from 3 to 5 hours, it increased from 8 to 18.

Animals↗
PubMed2004

Periosteal chondroma of the fifth toe--a case report.

A case of a periosteal chondroma arising in the fifth toe is reported. A 19-year-old man presented a palpable mass of his left fifth toe with pain for 2 years. Plain radiographs showed mild irregularity of the cortical bone of the fifth proximal phalanx. Magnetic resonance imaging revealed a tumour attached to the fifth proximal phalanx with low signal intensity on T1-weighted images and high signal intensity on T2-weighted images without intramedullary extension. The tumour was enhanced heterogeneously after intravenous injection of gadolinium diethylene triamine penta-acetic (GD-DTPA). The tumour was removed, together with the covering periosteum. It was diagnosed as periosteal chondroma histologically.

Adult↗
PubMedDate not supplied

Spiculated periosteal reaction in metastatic disease resembling osteosarcoma.

Sixteen cases of metastatic bone deposits presenting with sunburst spiculated periosteal reaction are presented. The most common origin was from prostatic carcinoma followed by neuroblastoma. A moderate soft tissue mass component was seen in 70% of the cases. The possible pathophysiologic reasons for this type of periosteal reaction are presented. The differential diagnosis is outlined.

Adenocarcinoma↗
PubMed1986

Periosteal chondroma with atypical behavior in a 9-year-old black female: case report.

Periosteal chondroma is an uncommon benign cartilaginous tumor of bone reported most often in children and young adults but is as of yet unreported in a black child. This is a case of periosteal chondroma in a 9-year-old black female with unusual findings of short duration of symptoms; large size; suspicious x-ray appearance and; aggressive behavior. The lesion was histologically benign and has not recurred six years post curettage.

Bone Neoplasms↗
PubMed2000

Long-term results of periosteal transplantation in osteochondritis dissecans of the knee.

Between 1986 and 1991, a total of 18 patients (11 men and 7 women) with osteochondritis dissecans of the knee were treated with periosteal transplantation. Median patient age was 19 years (range: 16-45 years). Eight patients were reoperated up to 8 years postoperatively, due to reduced range of motion, synovitis, or formation of an exostosis in the transplanted area. Of 14 patients who were available for follow-up after 8 years (range: 5-10), 2 were completely pain free. Six patients had reduced range of motion, knee instability, or quadriceps muscle atrophy. The number of reoperations and the presence of continued knee pain in most patients does not justify the extensive procedure of periosteal transplantation.

Adolescent↗
PubMed1999

A tarsal strip-periosteal flap technique for lateral canthal fixation.

Lateral canthal fixation is widely used. This article sought to determine if a periosteal flap used routinely in conjunction with a tarsal strip provides lasting lateral canthal fixation. This consecutive clinical series from two ambulatory surgery centers followed 79 patients who underwent 141 lateral canthal fixation procedures. Outcome was measured by the position of the lateral canthus. Correct positioning of the lateral canthus was achieved in 78 of 79 patients representing 139 of 141 procedures (98%). The failed case was a patient with floppy eyelid syndrome in whom the sutures tore through the tarsal strips. The tarsal strip-periosteal flap technique is a successful, technically direct method of lateral canthal fixation. It is promoted as an enhancement of the tarsal strip technique, and is especially helpful in patients with prominent eyes.

Aged↗
PubMed1992

[Periosteal and endosteal blood supply of the human fibula and its clinical importance].

The angioarchitecture of the human fibula was investigated by anatomical dissection. The main artery of the periosteal and endosteal blood supply is the arteria fibularis. The proximal part of the facies lateralis is additionally nourished by a well-built branch of the arteria tibialis anterior. The periosteal branches of the arteria fibularis are most voluminous on the dorsal side in the middle of the fibula. Small plates take care of these branches. For an additional revascularization the well-built branch of the arteria tibialis anterior is proposed. The best anatomical region for a vascularized fibular transfer is at an average of 20% up to 75% of the fibular length.

Aged↗
PubMedDate not supplied

DNA ploidy alterations detected during dedifferentiation of periosteal chondrosarcoma.

DNA ploidy of a case with dedifferentiated periosteal chondrosarcoma was analyzed by DNA cytofluorometry. The diagnosis of primary periosteal chondrosarcoma was made on the basis of the radiographic and histological findings. At 4 years after marginal resection, the tumor recurred locally and metastasized to various organs. The patient died of disease 2 years later. Histologically, there were two components, chondrosarcoma and malignant fibrous histiocytoma, in the recurrent and metastatic tumors. DNA ploidy analysis of multiple samples revealed that the primary lesion was composed of many diploid cells with some tetraploid and octaploid cells, whereas in the dedifferentiated area, there were many aneuploid cells which were not recognized in any area of the primary tumors. This case illustrated that DNA ploidy alteration of euploidy to aneuploidy is closely correlated with the process of dedifferentiation in chondrosarcoma.

Adult↗
PubMed1975

Stimulation of bone growth by periosteal stripping. A clinical study.

Periosteal stripping in the long lower limb bones of thirty children with shortening after poliomyelitis was performed. All have been followed up for five years. A relative increase in length attributable to the periosteal stripping procedure was seen in the majority. The conclusions are that this simple procedure is indicated in minor degrees of limb inequality in growing children, but that the haphazare response precludes any accurate estimation of the final outcome of such a procedure.

Adolescent↗
PubMed2002

[Periosteal Ewing's sarcoma].

Periosteal Ewing's sarcoma is a histologically typical Ewing's sarcoma arising in the periosteum with no involvement of the medullary canal or cancellous bone. We describe four cases in our experience and review the literature, recalling the usual computed tomography diagnostic criteria and the therapeutic consequences. Prognosis of periosteal Ewing's sarcoma is generally better than for ordinary Ewing's sarcoma. In order to avoid inoculating the canal, the operator must strictly avoid perforating the cortical during the biopsy. At surgical resection, cortical resection can be partial maintaining a continuous diaphysis; this should be examined as a possibility for young patients in order to avoid the problems encountered with massive reconstruction followed by chemotherapy.

Adolescent↗
PubMed1999

[Study of the bone formation and osteogenesis after transplantation of human periosteal mesenchymal stem cells].

OBJECTIVE: To study the bone formation and osteogenesis after transplantation of human periosteal mesenchymal stem cells(PMSC). METHODS: Suspension of PMSC which obtained from cell culture of periosteal segments in vitro were injected into the backs of nude mice subcutaneously, and the fracture site of neck of femur in old person. RESULTS: Subdermal nodules were observed by naked eyes after 11 days of transplantation. 4 weeks later, their anatomic diameter reached 2-7 mm(averaged 3.6 mm). It was proved that the subdermal nodules were trabecular ball trapped with fibrous tissue. The nodules were investigated by human special apoB gene with PCR, and the test of anti-human-tissue precipitin reaction(AHTPR). The results of PCR and AHTPR were positive reaction. There were no subdermal nodules formed in the sites of injection of frozen-melted PMSC or culture medium. The new callus in the sites of fracture were tested by PCR test, and two kinds of apoB gene products were detected. CONCLUSION: The results indicated that the implanted PMSC could form new bone directly in nude mice, and the cells of donor and recipient all could form new bone.

Animals↗
PubMed2002

[Repair of cartilage defect of knee joints with free periosteal autograft].

OBJECTIVE: To investigate the clinical application of periosteal autograft in repair of cartilage defect caused by osteoarthritis of knee. METHODS: From 1996 to 1999, 36 knees of cartilage defect of knee joint in 28 cases were treated. In the operation, the cracked degenerative cartilage was removed before free periosteum from tibia was transplanted to repair the defect, and the meniscuses in 8 kness of the 36 knees were reconstructed. After operation, early continuous passive movement was adopted for 4 weeks, and 8 knees with reconstruction of the meniscus were immobilized by plaster splint for 7 days after operation and before passive movement. All of the cases were followed up for 1 to 4 years before clinical evaluation in symptoms, signs and radiological findings. RESULTS: The general satisfactory rate was 86.1%, in which the function was excellent in 22 knees and good in 9 knees. CONCLUSION: The periosteal autograft is a good choice for repairing cartilage defect due to osteoarthritis, with a satisfactory outcome in the short term.

Cartilage, Articular↗