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[Surgical treatment of otosclerosis].

The purpose of the study was evaluation of the surgical treatment of otosclerosis by the method of small and large window. On the basis of four conversation frequencies hearing improvement was assessed in 44 ears after operation. Closure of cochlear reserve to 10 dB was obtained in 70.5% of cases. The mean hearing improvement was 29 dB. The best results were obtained with stapedotomy (small window method), particularly at 4 kHz frequencies.

Audiometry, Pure-Tone↗

Very far-advanced otosclerosis.

The term very far-advanced otosclerosis is proposed to indicate otosclerotic patients with both bone and air conduction thresholds nonmeasurable on a standard clinical audiometer (blank audiogram). Three of these patients have undergone stapedotomy with satisfactory results. This confirms that cochlear implantation is not the best treatment for all profoundly deaf patients at least with implants available today. Some of the patients with a blank audiogram are better off with exploratory tympanotomy and stapedotomy.

Adult↗

[Interleukin-1 beta and TNF alpha in serum of patients with otosclerosis].

Levels of interleukin-1 beta and tumor necrosis factor--alfa were determined using immunoradiometric method in the serum of patients who have gone surgical treatment due to otosclerosis. Values of both cytokines were higher in the serum of patients as compared with the control group. As regards TNF-alfa these differences were statistically significant.

Humans↗

[Otosclerosis--diagnosis and therapy].

Otosclerosis (synonym: otospongiosis) is a focal or diffuse spongifying disease of the bony labyrinth. So far pathogenesis is unknown, some recent investigations assume a paramyxovirus infection. But there are no doubts about hereditary and genetic factors, females are twice often affected as males with a maximum incidence between 20 and 40 years. If the disease invades the oval window niche it causes fixation of the stapes with conducting hearing loss. In some cases otospongiosis is associated with and presumably causes cochlear degeneration alone with sensoneurale hearing impairment of varying degree. The surgical technique is now well developed and the operative treatment enables in over 90% a closure of the air-bone gap by using stapes pistons. The medical therapy in cases of sensoneural hearing loss with sodium fluoride is still controversially discussed.

Adult↗

[Surgery of otosclerosis. Retrospective study and review of the literature].

Between 1990 and 1996 we have operated 134 patients with otosclerosis. 91 were female and 43 male with 42 years average. We report a retrospective study and collect a string of clinical preoperative variables analysing the kind of surgery performed with the findings and most relevant technical difficulties, complications and hearing improvement obtained just after the operation and one month later. Stapedectomy or stapedotomy have given good results in our serie with significant hearing recuperation on more than 90% of the cases well selected and operated by first time.

Adult↗

Neuroplasticity of auditory cortex after stape surgery for otosclerosis: a magnetoencephalographic study.

Aim of the present study was to investigate the tonotopic reorganization of the primary auditory cortex in otosclerotic patients following functional stapedioplasty. Characteristics of auditory cortex activation have been evaluated in a series of 10 otosclerotic patients before and after surgery. In these patients, a magnetoencephalographic recording of evoked magnetic fields has been performed by means of tone-burst monoaural stimulation with frequency octaves between 250 and 2000 Hz. Brain topography of cortex response generators (wave N100m) in patients with otosclerosis has been compared with that observed in a control group of 10 healthy subjects: changes before and after surgery have also been correlated with the functional result as far as concerns improvement in hearing. A significant reduction has been observed in the cortical tonotopic extension in response to the acoustic stimulus in patients "pre-surgery" in comparison with controls: after surgery, tonotopic mapping showed an increase, dimensions becoming comparable to those in control subjects. This increase in size was found to be significantly correlated with duration of the post-operative period. Data emerging from the present study suggest that the cortical auditory areas in man are involved in a "plastic" functional reorganization following changes in the receptor or peripheral deprivation. Reduction in the cortical tonotopic mapping resulting from prolonged lowering of auditory "input" is modified by reorganization of the cortex after the recovery of auditory function: this process occurs over a period of a few weeks.

Adult↗

Survival and evolution of vein grafts in otosclerosis surgery: structural and ultrastructural evidence.

The annular ligament of the stapes footplate measures 0.2 mm2 and contains elastic fibers that restrict perilymphatic movement to a molecular level. This resistance of the annular ligament prevents excessive movement of labyrinthine fluids that are potentially hazardous to the membranous and cellular structures of the inner ear. However, if the resistance of the annular ligament is overcome, then inner ear damage can occur. The vein graft, as used in our technique for otosclerosis surgery, occupies a space of 0.2 mm2 between the edge of the stapedotomy hole and the piston and has nearly the same compliance and resistance as the annular ligament of the stapes footplate. The vein graft becomes integrated with the middle-ear mucosa. It develops a rich and active blood supply and the smooth muscle cells and elastic fibers remain, although the latter show some modification of ultrastructural pattern. The graft becomes overlaid by the middle-ear epithelium. Even samples of vein graft that have been present for many years retain surviving elastic fibers, including those that have become fibrotic. In time, the number of elastic fibers increases as a result of the activity of fibroblasts, which build a poorly colored collagen.

Adult↗

Psychosocial aspects of acquired hearing impairment in the patients with otosclerosis.

UNLABELLED: Currently available evidence reveals comparatively few studies of the psychological and social effects of acquired hearing impairment, in spite of the fact that clinicians have for a long time been aware of a connection between acquired hearing impairment and mental disorders. The existing data indicate that psychological disorders are significantly more frequent in a population with hearing impairment than in the average population and are accompanied by disharmony in interpersonal and social relations. AIM: Establishing the presence and the type of mental disorders in patients with hearing impairment due to otosclerosis, before and 6 months after corrective surgery, as well as finding the role of adaptation style (personal adjustment) and facing strategy (communication strategies) as mediating variables between the acquired hearing impairment and observed psychical changes. METHODOLOGY: in 60 subjects, potential candidates for stapedectomy, MMPI-201 has been applied before and after surgery, in order to evaluate the mental state. For assessments of personal adjustment to the impairment and communication strategies, a communication personal profile has been applied preoperatively. RESULTS: more psychiatric disorders are present in the preoperative group compared to the general population and the postoperative group. These disorders are of exclusively a neurotic nature; the most frequent are depressive, anxious depressive and anxious reactions. A connection was found between adaptation style and facing strategies whether in the presence or absence of psychological disorders. CONCLUSION: the findings indicate a need for professional psychiatric-psychological support as a part of a rehabilitation program designed to reduce psychological difficulties, i.e. to help individuals to become adapted to the acoustic environment and to prevent or at least minimize the negative consequences of hearing impairment by efficient communication strategies.

Adaptation, Psychological↗

[Dehiscence of the anterior semicircular canal and otosclerosis: a case report].

UNLABELLED: The dehiscence of the anterior semicircular canal is a new clinical entity, it is necessary to consider this when a gusher occurs during stapedial surgery. CASE REPORT: We report a rare case of dehiscence of the anterior canal associated with otosclerosis. This was revealed by a gusher during the initial stapedectomy. At 3 months, an obliteration of the dehiscence was necessary by middle cranial fossa approach (persistant vestibular symptoms), seven months later. Revision stapedial surgery resulted in complete closure of the air-bone-gap. CONCLUSION: High resolution CT scans of the temporal bone are the key to diagnosis. It is necessary to appreciate this pathology with advances in canal and vestibular surgery.

Early Diagnosis↗

0.4 mm stapedotomy: a consistent technique for otosclerosis.

With the decline in the number of patients requiring stapes surgery for otosclerosis, there has been increasing concern over the ability of Otololaryngologists to perform these procedures. An approach must be easily learned, consistent and applicable to all operative situations. The technique of stapedotomy utilizing a 0.4-mm diameter fenestra, with placement of the prosthesis prior to removal of the stapes superstructure offers a consistent approach with low potential for morbidity. Fifty-six consecutive procedures of stapedotomy utilizing this approach were performed. Eighty-seven percent of cases had closure of the air-bone gap to within 10 dB, with 96 percent of the patients closing with 20 dB. There were no cases of perilymphatic fistula, sensorineural hearing loss or other otologic complications. This technique has proven reliable, while minimizing vestibular trauma.

Cochlear Implants↗

Cochlear otosclerosis presenting in children: a case report.

A case of cochlear otospongiosis in a 14-year-old is reviewed. The patient, who had a strong family history of otosclerosis corrected with stapes surgery, presented with a mild-to-moderate predominantly neurosensory hearing loss and absent stapes reflexes. A CT scan demonstrated changes characteristic of otospongiosis. The relevant literature was reviewed and fluorides as a possible therapy discussed.

Adolescent↗

[Subcophosis and otosclerosis. Medical and surgical treatment].

The spiral ligament of the stria vascularis is nearly always damaged by otosclerotic foci when the patient is nearly totally deaf because of otosclerosis. Vascular drugs are to be prescribed in such a case, besides the Sodium Fluoride treatment. The Sodium Fluoride is, according to us, the best treatment to arrest the progression of the otosclerotic disease. Sodium fluoride will destroy the proteolytic enzymes damaging the inner ear membranes and the hair of the Corti hair cells.

Audiometry↗

[Stapedectomy and a piston in otosclerosis].

At the Otolaryngological Clinic, Faculty Hospital Bratislava since 1971 to 1987 673 microsurgical operations on the stapes were made in patients with otosclerosis, incl. 73 using the method of stapedotomy and interposition of a teflon piston. The method was very successful. Hearing improved in 91.7% of the patients. In no instance marked deterioration of hearing or deafness developed. The surgical operation is associated with a smaller risk of damage to the inner ear. Patients tolerate stapedotomy well and the results are better than after stapedoplasties according to Schuknecht. The decibel gain is more even and at higher frequencies more marked than after stapedectomy. When the piston is used, greater precision and manual skill of the surgeon is essential, as compared with stapedectomy.

Adolescent↗

CO2 laser for otosclerosis: safe energy parameters.

Safe energy parameters for each Sharplan CO2 laser model (734, 1040, 1100A) were established in the laboratory. Ultrasensitive pyroelectric detectors analyzed the precise energy package delivered to the operative field with each of these power setting. Subsequently, 0.6-mm stapedotomy and stapedectomy revisions were performed under simulated operating room conditions while measuring temperature changes in the vestibule with a thermocouple. Table I illustrates safe energy settings for each of the Sharplan CO2 models tested. These power settings produced no more than 0.3 degrees C temperature rise in the vestibule during stapedotomy, and no more than 0.5 degrees C during stapedectomy revision. Following these guidelines, the CO2 laser was then employed to perform stapedotomy and stapedectomy revisions in otosclerosis patients. In over 200 consecutive operations performed under local anesthesia with the CO2 laser, no patient became dizzy intraoperatively while the CO2 laser was applied to the stapes footplate or the oval window neomembrane, confirming the lack of significant caloric effect to the inner ear at these energy settings. More importantly, no patient has yet experienced significant sensorineural hearing loss in the speech range.

Carbon Dioxide↗

[Tarflen-metal prosthesis in the surgical treatment of otosclerosis].

The authors described the prosthesis for otosclerosis surgery. It is made by plastic material connected with the tantalum+ or platinum wire. The mode of prosthesis adaptation and taking into the place was described. The prosthesis was devised and produced by Instytut Przemysłu Tworzyw i Farb Gliwice (Poland).

Humans↗

Fluoride therapy for otosclerosis.

From the extensive morphological studies performed, otosclerosis appears to be ubiquitous, and in many instances subclinical. Despite reports of the efficacy of fluoride for this condition, at present its use should be regarded as experimental.

Fluorides↗

Vertigo in postoperative follow-up of otosclerosis.

Causes of vertigo after otosclerosis surgery were studied postoperatively and in long-term follow-up examinations. Pressure and mobility changes in the posterior labyrinth fluids, enzymatic process, and decrease in blood supply at the time of operation appear to be the major causes. Methods of detection, avoiding, and managing vertigo are presented.

Follow-Up Studies↗

[Sound injuries after surgery of otosclerosis].

Surgery for otosclerosis means that the sound protection due to the fixation of the footplate does not exist anymore. As the Corti hair cells have been fragilized by proteolytic enzymes, it is absolutely necessary to reconstruct the sound mechanism in order to maintain the vibration of the perilymph absolutely within acoustical physiologic limit of movement. The means to realize this reconstruction are presented in this paper, as well as the results.

Hearing Loss, Noise-Induced↗