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PubMed1985

Swine dysentery in a sow herd. I. Clinical manifestation and elimination of the disease with a combination of lincomycin and spectinomycin.

An acute outbreak of swine dysentery (Doyle) on a farrowing farm is described. Besides clinical signs of enteritis a general loss of condition was seen throughout the herd. This resulted in a decreased fertility and breeding performance among sows and an increase in piglet mortality. Several dehydrated sows aborted. The outbreak was stopped by oral treatment with lincomycin/spectinomycin 1:1. In the course of the treatment all animals and buildings were washed and disinfected. The use of pharmacotherapeutics in treating swine dysentery is discussed with emphasis on the involuntary induction of carriers.

Animals↗
PubMed1986

Resistance of Mycoplasma pneumoniae to macrolides, lincomycin and streptogramin B.

Of four strains of Mycoplasma pneumoniae, highly resistant to erythromycin and related antibiotics, three were homogeneously resistant, but the fourth showed heterogeneous resistance, with only 1% of the cells manifesting this property. Stable, homogeneous resistance was generated in this strain in the presence of erythromycin, whereas the heterogeneous resistance was lost spontaneously on passage in the absence of antibiotics, or on treatment with acridine orange. The mechanism of induction of stable resistance appears to be different from that seen in Staphylococcus aureus.

Acridine Orange↗