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Results for “Hyperpigmentation”

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A computer controlled scanner for the laser treatment of vascular lesions and hyperpigmentation.

A computer controlled scanner has been used with a copper vapour laser for the treatment of vascular lesions and hyperpigmented lesions. The computer controls the position and speed of travel of the laser spot during treatment. The illumination time is adjustable with a minimum of 1 ms. The light from the laser is scanned over the lesion so that the lesion is 'painted in' in a raster-like scan of arbitrary shape and produces a series of parallel lines 0.6 mm apart.

Computers↗

Hyperpigmentation associated with oral minocycline.

Two patient receiving minocycline developed blue-black pigmentation on the legs. Biopsies from the pigmented areas demonstrated granules containing iron, a pigment with staining properties similar to melanin, and a third pigment which may be a degradation product of minocycline. Electron microscopy showed that some, but not all the granules were membrane-bound and they were situated mainly within macrophages. Analytical electron microscopy showed that the granules contained iron, sulphur, chlorine and, in one case, calcium.

Adult↗