Establishing trimester- and ethnic group-related reference ranges for fructosamine and HbA1c in non-diabetic pregnant women.
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Measurement of glycated proteins, especially haemoglobins, is now a routine procedure for monitoring previous glycaemic control in diabetic patients in the developed world. Until recently, however, the assays were sophisticated and costly and, therefore, were only rarely used in developing countries. With easier and cheaper tests now available, the measurement of glycaemic control could be also introduced into regional hospitals in developing countries. This paper reviews feasible methods for clinical laboratories with limited resources. Recent experiences from African countries are included.
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GH and FA are useful monitors in the care of diabetic patients. For most situations, GH is the preferred test and should be routinely monitored. FA should be reserved for exceptional situations in which blood glucose control over one to two weeks must be assessed or in patients with a hemoglobinopathy. Patients with diabetes should be advised of their present GH level and the preferred goal.
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